专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20100241041A1 Knee Brace with Expandable Members and Method of Using the Same 有权
标题翻译：具有可扩展成员的膝盖支架及其使用方法
公开(公告)号：US20100241041A1
公开(公告)日：2010-09-23
申请号：US12668673
申请日：2008-07-18
申请人： David J. Hunter , Glenn Colaco , Dimitrije Stamenovic
发明人： David J. Hunter , Glenn Colaco , Dimitrije Stamenovic
IPC分类号： A61F5/00
CPC分类号： A61F5/0125 , A61F5/0106 , A61F5/0109 , A61F5/0123
摘要： A knee brace (300) has a body (310) supporting first, second, and third expandable members (330). When expanded, the first, second, and third expandable members are positioned on the brace body to provide a counteracting force to the adduction moment of the knee.
摘要翻译：膝盖支架（300）具有支撑第一，第二和第三可膨胀元件（330）的主体（310）。当扩张时，第一，第二和第三可扩张构件位于支架主体上，以向膝盖的内收力提供抵消力。

2. 发明授权

US4935404A Phosphorus containing peptides, pharmaceutical compositions and method of treating collagenolytic conditions 失效
标题翻译：含磷的肽，药物组合物和治疗胶原水解条件的方法
公开(公告)号：US4935404A
公开(公告)日：1990-06-19
申请号：US270085
申请日：1988-11-14
申请人： David J. Hunter , Roger E. Markwell , Robert W. Ward
发明人： David J. Hunter , Roger E. Markwell , Robert W. Ward
IPC分类号： A61K38/55 , A61K38/00 , A61P29/00 , A61P35/00 , A61P37/08 , A61P43/00 , C07F9/30 , C07F9/38 , C07F9/40 , C07F9/572 , C07K5/06
CPC分类号： C07F9/4006 , C07K5/06191 , A61K38/00
摘要： Novel compounds of the formula (I), a process for their preparation and their use as collagenase inhibitors are described: ##STR1## in which R.sub.1 is hydrogen or hydroxy; R.sub.2 is hydrogen or alkyl; R.sub.3 is C.sub.3-6 alkyl; R.sub.4 is hydrogen, alkyl, --CH.sub.2 --Z where Z is optionally substituted phenyl or heteroaryl, or R.sub.4 is a group ##STR2## where R.sub.8 is hydrogen, alkyl or --CH.sub.2 --Ph where Ph is optionally substituted phenyl, and R.sub.9 is hydrogen or alkyl; and R.sub.5 is hydrogen or alkyl.

3. 发明授权

US5212163A Compounds 失效
标题翻译：化合物
公开(公告)号：US5212163A
公开(公告)日：1993-05-18
申请号：US758356
申请日：1991-09-09
申请人： Robert W. Ward , Roger E. Markwell , David J. Hunter
发明人： Robert W. Ward , Roger E. Markwell , David J. Hunter
IPC分类号： C07F9/38 , C07F9/40 , C07F9/553 , C07F9/572 , C07K5/06 , C07K5/08
CPC分类号： C07F9/3808 , C07F9/4006 , C07F9/5532 , C07F9/5728 , C07K5/06191 , C07K5/0827
摘要： Novel compounds of formula (I) and salts, solvates and hydrates thereof, processes for their preparation and their use in the treatment of conditions in which degradation of connective tissue and other proteinaceous components of the body occurs: ##STR1## in which, R is hydrogen, C.sub.1-6 alkyl or optionally substituted benzyl; R.sub.1 is hydrogen or C.sub.1-6 alkyl; R.sub.2 is C.sub.3-6 alkyl; R.sub.3 is hydrogen, alkyl, --CH.sub.2 --Z where Z is optionally substituted phenyl or heteroaryl, or R.sub.3 is a group ##STR2## where R.sub.7 is hydrogen, alkyl or --CH.sub.2 --Ph where Ph is optionally substituted phenyl and R.sub.8 is hydrogen or alkyl; and R.sub.4 is --CH.sub.2 --(CH.sub.2).sub.n OR.sub.5 or --CH.sub.2 --(CH.sub.2).sub.n OCOR.sub.6 or --CH(R.sub.9)COR.sub.10, where n is an integer from 1 to 6; R.sub.5, R.sub.6 and R.sub.9 are hydrogen or C.sub.1-6 alkyl; and R.sub.10 is hydroxy or --O--C.sub.1-6 alkyl or --NR.sub.5 R.sub.6 (where R.sub.5 and R.sub.6 may be linked to form a heterocyclic ring; or R.sub.3 and R.sub.4 are joined together as --(CH.sub.2).sub.m -- where m is an integer from 4 to 12.
摘要翻译：式（I）的新型化合物及其盐，溶剂化物和水合物，其制备方法及其用于治疗结缔组织和身体其它蛋白质成分降解的病症发生：其中（I），R为氢，C 1-6烷基或任选取代的苄基; R1是氢或C1-6烷基; R2是C3-6烷基; R3是氢，烷基，-CH2-Z，其中Z是任选取代的苯基或杂芳基，或R3是基团，其中R7是氢，烷基或-CH2-Ph，其中Ph是任选取代的苯基，R8是氢或烷基 ; 并且R 4是-CH 2 - （CH 2）nOR 5或-CH 2 - （CH 2）nOCOR 6或-CH（R 9）COR 10，其中n是1至6的整数; R5，R6和R9是氢或C1-6烷基; 并且R 10是羟基或-O-C 1-6烷基或-NR 5 R 6（其中R 5和R 6可以连接形成杂环;或者R 3和R 4连接在一起作为 - （CH 2）m - ，其中m是4的整数到12岁

4. 发明授权

US4745115A Isoquinolines or benzisoquinoliner having antiinflammatory activity 失效
公开(公告)号：US4745115A
公开(公告)日：1988-05-17
申请号：US789105
申请日：1985-10-18
申请人： Roger E. Markwell , Stephen A. Smith , David J. Hunter
发明人： Roger E. Markwell , Stephen A. Smith , David J. Hunter
IPC分类号： A61K31/435 , A61K31/47 , A61K31/472 , A61K31/473 , A61P29/00 , A61P37/08 , C07D217/22 , C07D217/24 , C07D221/08 , C07D221/10 , C07D401/04
CPC分类号： C07D401/04 , C07D217/22 , C07D217/24 , C07D221/08 , C07D221/10
摘要： Compounds of the general formula I ##STR1## in which: R.sub.1 and R.sub.2 are independently hydrogen, C.sub.1-6 alkyl or together are a group X which is C.sub.3-6 polymethylene optionally in which one carbon atom is replaced by O, S or NR.sub.6 wherein R.sub.6 is hydrogen or C.sub.1-6 alkyl;R.sub.3 is a mono- or fused bi-cyclic heteroaromatic group having up to ten atoms in the aromatic ring(s), not more than four of which are selected from nitrogen, oxygen or sulphur, optionally C-substituted by one or more substituents selected from halogen, CF.sub.3, nitro, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, C.sub.2-7 alkanoyl or cyano; or is phenyl or naphthyl, optionally substituted by one or more substituents selected from halogen, CF.sub.3, nitro, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, C.sub.2-7 alkanoyl, carboxyl, C.sub.1-6 alkoxycarbonyl, cyano, CONR.sub.7 R.sub.8 wherein R.sub.7 and R.sub.8 are selected from hydrogen or C.sub.1-6 alkyl or together are a group X; NR.sub.9 R.sub.10 wherein R.sub.9 and R.sub.10 are selected from hydrogen, C.sub.1-6 alkyl, C.sub.2-7 alkanoyl or C.sub.1-6 alkylsulphonyl or together are a group X; SO.sub.2 NR.sub.11 R.sub.12 wherein R.sub.11 and R.sub.12 are selected from hydrogen or C.sub.1-6 alkyl or together are a group X; or S(O).sub.m R.sub.13 wherein m is 1 or 2 and R.sub.13 is C.sub.1-6 alkyl; Z is naphthyl or a mono- or fused bicyclic heteroaromatic ring having up to ten atoms in the aromatic ring(s), not more than four of which are selected from nitrogen, oxygen or sulphur or (when R.sub.3 is an optionally substituted naphthyl or heteroaromatic group as defined) Z is a phenyl ring; and Z is optionally C-substituted by one or two substituents R.sub.4 and R.sub.5 which are independently selected from C.sub.1-6 alkyl, cyano, amino, aminocarbonyl or aminocarbamoyl optionally substituted by one or two C.sub.1-6 alkyl groups or by a group X, halogen, CF.sub.3, nitro, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, C.sub.2-7 alkanoyloxy or hydroxy, or together on adjacent carbon atoms are methylenedioxy or C.sub.3-5 polymethylene,are disclosed as an active therapeutic substances for the treatment of inflammatory conditions.

5. 发明授权

US06726292B1 Full off-set two-piece fiber reinforced composite wheel using spoke or web area box sections 有权
标题翻译：使用辐条或网箱区域的全套两件式纤维增强复合轮
公开(公告)号：US06726292B1
公开(公告)日：2004-04-27
申请号：US09626810
申请日：2000-07-27
申请人： Del C Schroeder , John G Argeropoulos , Jeremy A Panasiewicz , David J Hunter , David G Speth , Suresh Nagesh
发明人： Del C Schroeder , John G Argeropoulos , Jeremy A Panasiewicz , David J Hunter , David G Speth , Suresh Nagesh
IPC分类号： B60B502
CPC分类号： B60B5/02
摘要： A two piece fiber reinforced composite wheel includes a molded inner rim portion defining an outboard engagement surface and a molded outer rim portion defining an inboard engagement surface. The inner and outer rim portions are conformed so as to interlock together and are adhesively bonded. The inner and outer rim portions engage forming a plurality of spoke sections having substantially box shaped cross sections. The spoke sections are further connected with fasteners.
摘要翻译：两片纤维增强复合轮包括限定外侧接合表面的模制内缘部分和限定内侧接合表面的模制外缘部分。内圈和外圈部分相互贴合，并且粘接在一起。内边缘部分和外边缘部分接合形成具有基本上盒形截面的多个辐条部分。轮辐部分进一步与紧固件连接。

6. 发明授权

US08333723B2 Knee brace with expandable members and method of using the same 有权
标题翻译：具有可扩展成员的膝盖支架及其使用方法
公开(公告)号：US08333723B2
公开(公告)日：2012-12-18
申请号：US12668673
申请日：2008-07-18
申请人： David J. Hunter , Glenn Colaco , Dimitrije Stamenovic
发明人： David J. Hunter , Glenn Colaco , Dimitrije Stamenovic
IPC分类号： A61F5/00
CPC分类号： A61F5/0125 , A61F5/0106 , A61F5/0109 , A61F5/0123
摘要： A knee brace (300) has a body (310) supporting first, second, and third expandable members (330). When expanded, the first, second, and third expandable members are positioned on the brace body to provide a counteracting force to the adduction moment of the knee.
摘要翻译：膝盖支架（300）具有支撑第一，第二和第三可膨胀元件（330）的主体（310）。当扩张时，第一，第二和第三可扩张构件位于支架主体上，以向膝盖的内收力提供抵消力。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式