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    • 3. 发明授权
    • Method and apparatus for measuring osmotic pressure
    • 用于测量渗透压的方法和装置
    • US06450014B1
    • 2002-09-17
    • US09473071
    • 1999-12-28
    • David C. Boris
    • David C. Boris
    • G01N1304
    • G01N13/04G01N1/38G01N2001/4016
    • A method and apparatus are provided for the measuring osmotic pressure of a solution. A sample of a solution is placed into a sample cell above a membrane supported in the sample cell and the sample cell is sealed. Gas at an elevated pressure is introduced into the sample cell to drive a quantity of dialyzate through the membrane and into a transparent dialyzate exit tube adapted to receive the dialyzate which passes through the membrane. The elevated pressure of the gas is varied through a pressure regulator to yield a substantially stationary dialyzate meniscus in the transparent dialyzate exit tube. The pressure in the sample cell is measured by reading a pressure gauge showing the elevated pressure of the gas that yielded the substantially stationary dialyzate meniscus, the elevated pressure of the gas being substantially equivalent to the osmotic pressure of the sample.
    • 提供了用于测量溶液的渗透压的方法和装置。 将溶液样品放入支撑在样品池中的膜上方的样品池中,并将样品池密封。 将升高的压力的气体引入样品池中以通过膜驱动一定量的透析液并进入适于接收通过膜的透析液的透明透析液出口管。 通过压力调节器改变气体的升高压力,以在透明透析液出口管中产生基本上固定的透析液弯液面。 通过读取示出产生基本上固定的透析液半月板的气体的升高的压力表来测量样品池中的压力,气体的升高压力基本上等于样品的渗透压。
    • 4. 发明授权
    • Method for generating a solution with a predetermined osmotic pressure
    • 用于产生具有预定渗透压的溶液的方法
    • US06397666B1
    • 2002-06-04
    • US09473444
    • 1999-12-28
    • David C. Boris
    • David C. Boris
    • G01N1304
    • G01N13/04
    • A method is provided for determining the concentration of a solution having a predetermined osmotic pressure and/or for generating a solution with a predetermined osmotic pressure. The method is performed by placing a sample of a solution into a sample cell, the sample cell including therein a membrane supported therein; sealing the sample in the sample cell; introducing gas at a predetermined elevated pressure substantially equal to the predetermined osmotic pressure; and generating a dialyzate by allowing the solution to dialyze through the membrane until equilibrium is achieved and no more dialyzate passes through while the sample cell is maintained at the predetermined elevated pressure, the sample remaining in the sample cell having an osmotic pressure substantially equal to the predetermined elevated pressure; collecting the dialyzate of said generating step; and weighing the dialyzate of said collecting step to determine the concentration of the solution remaining in the sample cell.
    • 提供了一种用于确定具有预定渗透压的溶液的浓度和/或产生具有预定渗透压的溶液的方法。 该方法通过将溶液样品放置在样品池中来进行,样品池中包含有一个膜,该膜包含在其中; 将样品密封在样品池中; 以基本上等于预定渗透压的预定升高的压力引入气体; 并且通过使溶液透析膜直至达到平衡并且当样品池保持在预定的高压时不再透析透析液而产生透析液,残留在样品池中的样品的渗透压基本上等于 预定升高的压力; 收集所述生成步骤的透析液; 并称重所述收集步骤的透析液以确定残留在样品池中的溶液的浓度。
    • 7. 发明授权
    • Method for measuring changes in osmotic pressure
    • 测量渗透压变化的方法
    • US06267003B1
    • 2001-07-31
    • US09474151
    • 1999-12-28
    • David C. Boris
    • David C. Boris
    • G01N1304
    • G01N13/04
    • A method is provided which allows for monitoring changes in osmotic pressure of a sample as a function of time and/or temperature. This is accomplished by placing a sample of a solution at an initial temperature into the sample cell above the membrane supported in the sample cell; sealing the sample in the sample cell; introducing gas at an elevated pressure to the sample cell to generate a dialyzate by allowing a portion of the solution to dialyze through the membrane; varying the elevated pressure of the gas until equilibrium across the membrane is substantially achieved; changing the temperature of the solution over time; measuring the osmotic pressure at predetermined intervals of time; and calculating the changes in the osmotic pressure. Alternatively, the method for monitoring changes in osmotic pressure of a sample (wherein the changes are the result of a chemical reaction generated in the sample cell) can be practiced by placing a sample of a solution at an initial temperature into a sample cell above a membrane supported in the sample cell; adding reactants to the sample; sealing the sample and reactants in the sample cell; introducing gas at an elevated pressure to the sample cell to generate a dialyzate by allowing a portion of the solution to dialyze through the membrane; varying the elevated pressure of the gas until equilibrium across the membrane is substantially achieved; measuring the osmotic pressure at predetermined intervals of time; and calculating the changes in the osmotic pressure.
    • 提供了一种方法,其允许监测作为时间和/或温度的函数的样品的渗透压变化。 这是通过将溶液样品置于样品池中的膜上方的样品池中的初始温度来实现的。 将样品密封在样品池中; 将气体以升高的压力引入样品池,以通过使溶液的一部分透过膜产生透析液; 改变气体的升高的压力,直到基本达到膜的平衡; 随时间改变溶液的温度; 以预定的时间间隔测量渗透压; 并计算渗透压的变化。 或者,用于监测样品(其中变化是在样品池中产生的化学反应的结果)的渗透压变化的方法可以通过将溶液样品置于初始温度下来进行, 膜支撑在样品池中; 向样品中加入反应物; 密封样品池中的样品和反应物; 将气体以升高的压力引入样品池,以通过使溶液的一部分透过膜产生透析液; 改变气体的升高的压力,直到基本达到膜的平衡; 以预定的时间间隔测量渗透压; 并计算渗透压的变化。