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1. 发明授权

US10342614B2 Triaxial antenna for microwave tissue ablation 有权
公开(公告)号：US10342614B2
公开(公告)日：2019-07-09
申请号：US13563050
申请日：2012-07-31
申请人： Daniel W. van der Weide
发明人： Daniel W. van der Weide
IPC分类号： A61B18/18 , A61B18/00
摘要： An improved antenna for microwave ablation uses a triaxial design which reduces reflected energy allowing higher power ablation and/or a smaller diameter feeder line to the antenna.

2. 发明授权

US08672932B2 Center fed dipole for use with tissue ablation systems, devices and methods 有权
标题翻译：用于组织消融系统，装置和方法的中心馈入偶极子
公开(公告)号：US08672932B2
公开(公告)日：2014-03-18
申请号：US11728457
申请日：2007-03-26
申请人： Daniel W. van der Weide , Fred T. Lee, Jr. , Paul F. Laeseke , Christopher L. Brace
发明人： Daniel W. van der Weide , Fred T. Lee, Jr. , Paul F. Laeseke , Christopher L. Brace
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1477 , A61B18/1815 , A61B2018/183
摘要： The present invention relates to systems and devices for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In particular, the present invention relates to systems and devices for the delivery of energy employing a center fed dipole component. In certain embodiments, methods are provided for treating a tissue region (e.g., a tumor) through application of energy with the systems and devices of the present invention.
摘要翻译：本发明涉及用于将各种应用的能量递送到组织的系统和装置，包括医疗程序（例如，组织消融，切除，烧灼，血管血栓形成，心律失常和心律失常的治疗，电外科，组织收获等）。）。特别地，本发明涉及用于使用中心馈送偶极子部件传送能量的系统和装置。在某些实施方案中，提供了通过与本发明的系统和装置一起施加能量来治疗组织区域（例如肿瘤）的方法。

3. 发明授权

US07691298B2 Plastic cantilevers for force microscopy 有权
标题翻译：用于力显微镜的塑料悬臂
公开(公告)号：US07691298B2
公开(公告)日：2010-04-06
申请号：US11041886
申请日：2005-01-21
申请人： Daniel W. van der Weide , Charles A. Paulson , Andrew G. Stevens
发明人： Daniel W. van der Weide , Charles A. Paulson , Andrew G. Stevens
IPC分类号： B29C67/00
CPC分类号： B29C33/3878 , B29C37/0003 , G01Q60/54 , G01Q70/14
摘要： A method disclosed for producing polymer-based cantilevers for use in atomic force microscopy in a batch process. The method includes forming a mold in a mold material, for example PDMS, using a master cantilever, removing the master cantilever from the mold material to reveal a mold cavity, filling the mold cavity with plastic, for example polystyrene, to form a plastic cantilever in the mold, and removing the plastic cantilever from the mold, for example using adhesive tape or flexing the mold. At least one surface of the plastic cantilever can be coated with a reflective metal, such as gold. The plastic cantilever can be functionalized for use in magnetic force microscopy by attaching a probe tip formed of magnetic metal, for example a 10 μm nickel sphere.
摘要翻译：公开了用于在分批工艺中用于原子力显微镜的聚合物基悬臂的方法。该方法包括使用主悬臂在模具材料（例如PDMS）中形成模具，从模具材料移除主悬臂以露出模具腔，用塑料（例如聚苯乙烯）填充模腔，以形成塑料悬臂在模具中，并且从模具中移除塑料悬臂，例如使用胶带或使模具弯曲。塑料悬臂的至少一个表面可以涂覆有诸如金的反射金属。塑料悬臂可以通过安装由磁性金属形成的探针尖端（例如10μm的镍球）来实现磁力显微镜的功能化。

4. 发明申请

US20150199602A1 RADIO-FREQUENCY IDENTIFICATION TAGS 有权
标题翻译：无线电频率识别标签
公开(公告)号：US20150199602A1
公开(公告)日：2015-07-16
申请号：US14593833
申请日：2015-01-09
申请人： Daniel W. van der Weide , Marcos Martinez
发明人： Daniel W. van der Weide , Marcos Martinez
IPC分类号： G06K19/077 , G06K7/10
CPC分类号： G06K7/10366 , G06K19/0672
摘要： The present invention relates to radio-frequency identification (RFID) tags that produce a unique radar signature by passive reflection of an electromagnetic signal. In particular, provided herein are frequency-, phase-, and/or amplitude-shift encoded RFID tags, and methods of use and manufacture thereof.
摘要翻译：本发明涉及通过电磁信号的被动反射产生独特的雷达特征的射频识别（RFID）标签。特别地，本文提供了频移，相位和/或幅移码编码的RFID标签及其使用和制造方法。

5. 发明授权

US06801029B2 Microwave dielectric spectroscopy method and apparatus 有权
标题翻译：微波介电光谱法和仪器
公开(公告)号：US06801029B2
公开(公告)日：2004-10-05
申请号：US10269833
申请日：2002-10-11
申请人： Daniel W. van der Weide , Kimberly M. Taylor
发明人： Daniel W. van der Weide , Kimberly M. Taylor
IPC分类号： G01S302
CPC分类号： G01N22/00
摘要： Dielectric spectroscopy is carried out by coupling non-radiated microwave energy from an antenna to a sample to detect changes in the permittivity of the sample within the antenna's near field. The frequency response of the antenna exhibits resonant frequencies in a frequency range of interest. Changes in the sample as a result of changes in environmental conditions of the sample are exhibited as changes in the antenna's resonant frequency or frequencies. The changes in the positions of the peaks with changes in environmental conditions can be correlated to changes in the condition of the sample, such as unfolding of proteins with increases in temperature of the sample.
摘要翻译：通过将来自天线的非辐射微波能量耦合到样品来进行电介质光谱，以检测天线近场内样品的介电常数的变化。天线的频率响应在感兴趣的频率范围内呈现谐振频率。作为样品的环境条件变化的结果，样品的变化表现为天线谐振频率或频率的变化。具有环境条件变化的峰位置的变化可以与样品条件的变化相关，例如随着样品温度升高蛋白质的折叠。

6. 发明授权

US06649402B2 Microfabricated microbial growth assay method and apparatus 有权
公开(公告)号：US06649402B2
公开(公告)日：2003-11-18
申请号：US09887647
申请日：2001-06-22
申请人： Daniel W. Van der Weide , Frederick R. Blattner
发明人： Daniel W. Van der Weide , Frederick R. Blattner
IPC分类号： C12M134
CPC分类号： C12M23/12 , C12M23/20 , C12M23/22 , C12M41/36
摘要： Microbial growth assays are carried out utilizing assay apparatus having a base plate with a plurality of microbial growth assay wells, each well having a liquid content of 30 &mgr;l or less. Electrodes are coupled together through the wells and electrical connectors are connected to the electrodes to allow the effect of the content of the wells to be measured by measuring the capacitance or resistance or both between the electrodes at each well, with the change in the capacitance or resistance in each well over time being correlated with the extent of growth of a bacterium introduced into the well with a growth medium. The small size of the microwells causes the growth of bacteria in the well to quickly show a change in the electrical properties of the well, particularly in the capacitance or resistance between the electrodes at each well, with growth to saturation occurring for common bacteria such as E. coli in a few hours or less. High density base plates may be tested with a large variety of substances that may have an effect on the growth of the bacteria in the well over a relatively short period of time, allowing high throughput while maintaining the accuracy of the test.

7. 发明授权

US06597010B2 Solid-state quantum dot devices and quantum computing using nanostructured logic gates 有权
公开(公告)号：US06597010B2
公开(公告)日：2003-07-22
申请号：US10093960
申请日：2002-03-08
申请人： Mark A. Eriksson , Mark G. Friesen , Robert J. Joynt , Max G. Lagally , Daniel W. van der Weide , Paul Rugheimer , Donald E. Savage
发明人： Mark A. Eriksson , Mark G. Friesen , Robert J. Joynt , Max G. Lagally , Daniel W. van der Weide , Paul Rugheimer , Donald E. Savage
IPC分类号： H01L2906
CPC分类号： G06N99/002 , B82Y10/00 , Y10S977/933
摘要： Semiconductor dot devices include a multiple layer semiconductor structure having a substrate, a back gate electrode layer, a quantum well layer, a tunnel barrier layer between the quantum well layer and the back gate, and a barrier layer above the quantum well layer. Multiple electrode gates are formed on the multi-layer semiconductor with the gates spaced from each other by a region beneath which quantum dots may be defined. Appropriate voltages applied to the electrodes allow the development and appropriate positioning of the quantum dots, allowing a large number of quantum dots be formed in a series with appropriate coupling between the dots.

8. 发明申请

US20120316551A1 Triaxial Antenna for Microwave Tissue Ablation 审中-公开
标题翻译：用于微波组织消融的三轴天线
公开(公告)号：US20120316551A1
公开(公告)日：2012-12-13
申请号：US13563050
申请日：2012-07-31
申请人： Daniel W. van der Weide
发明人： Daniel W. van der Weide
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/00023
摘要： An improved antenna for microwave ablation uses a triaxial design which reduces reflected energy allowing higher power ablation and/or a smaller diameter feeder line to the antenna.
摘要翻译：用于微波消融的改进的天线使用三轴设计，其减少反射能量，允许更高功率消融和/或更小直径的馈线到天线。

9. 发明授权

US07135917B2 Left-handed nonlinear transmission line media 有权
标题翻译：左旋非线性传输线介质
公开(公告)号：US07135917B2
公开(公告)日：2006-11-14
申请号：US10860389
申请日：2004-06-03
申请人： Alexander B. Kozyrev , Daniel W. van der Weide
发明人： Alexander B. Kozyrev , Daniel W. van der Weide
IPC分类号： H03F7/06 , H04B3/04
CPC分类号： H03F7/00
摘要： A left-handed nonlinear transmission line system has multiple nonlinear capacitors connected in series between input and output terminals and multiple inductances connected in parallel between the nonlinear capacitors and a return conductor extending between the input and output terminals. The nonlinear capacitors have a capacitance characteristic that changes with the voltage applied across the capacitors, such as a capacitance that decreases with increasing voltage. A radio frequency signal source is coupled to the input terminals and provides power at a selected drive frequency. Depending on the frequency of the drive signal with respect to the Bragg cutoff frequency of the nonlinear transmission line, the output signal may include a strong signal component at the third harmonic of the input drive signal frequency, components at higher harmonics, or components at fractional frequencies of the input drive signal frequency. Parametric generation of other signal waves that are phase matched with the signal wave produced by the input drive signal is also possible under appropriate conditions. The left-handed nonlinear transmission line system generates such output signal frequencies with high efficiency.
摘要翻译：左手非线性传输线系统具有串联连接的输入和输出端子之间的多个非线性电容器和非线性电容器之间并联的多个电感器以及在输入和输出端子之间延伸的返回导体。非线性电容器具有随着施加在电容器两端的电压而变化的电容特性，例如随着电压增加而减小的电容。射频信号源耦合到输入端并以选定的驱动频率提供功率。取决于相对于非线性传输线的布拉格截止频率的驱动信号的频率，输出信号可以包括输入驱动信号频率的三次谐波处的强信号分量，高次谐波处的分量或分数分量输入驱动信号频率的频率。与输入驱动信号产生的信号波相位匹配的其他信号波的参数生成在适当的条件下也是可能的。左手非线性传输线系统以高效率产生这种输出信号频率。

10. 发明授权

US07368305B2 High aspect ratio micromechanical probe tips and methods of fabrication 有权
标题翻译：高纵横比微机械探针尖端和制造方法
公开(公告)号：US07368305B2
公开(公告)日：2008-05-06
申请号：US11150856
申请日：2005-06-10
申请人： Daniel W. van der Weide , Yaqiang Wang
发明人： Daniel W. van der Weide , Yaqiang Wang
IPC分类号： H01L21/00
CPC分类号： G01Q60/38 , G01Q60/06 , G01Q60/22 , Y10T428/24521
摘要： A method of fabricating high aspect ratio micromechanical tips is provided. The method includes, but is not limited to, forming an etchant protective island on a surface of a silicon substrate with the silicon substrate exposed around the island; isotropically etching the silicon substrate by reactive ion etching around the protective island to partially undercut the silicon substrate beneath the protective island; anisotropically etching, by deep reactive ion etching, the silicon surrounding the island to a desired depth to define a tip shaft of the desired height supported at a base by the substrate; removing the protective island from the tip; and sharpening the top of the tip shaft to an apex. Using the method, micromechanical tips having heights greater than at least 30 μm have been obtained while maintaining the vertical sidewall necessary for both AFM and scanning near-field microwave microscopy (SNMM) profiling applications.
摘要翻译：提供制造高宽比微机械尖端的方法。该方法包括但不限于在硅衬底的表面上形成蚀刻剂保护岛，其中硅衬底暴露在岛附近; 通过围绕保护岛的反应离子蚀刻来均匀蚀刻硅衬底，以部分地削弱保护岛下方的硅衬底; 通过深反应离子蚀刻将各向异性蚀刻，围绕岛的硅到期望的深度，以限定由基底在基部处支撑的所需高度的尖端轴; 从尖端移除保护岛; 并将尖端轴的顶部锐化为顶点。使用该方法，在保持AFM和扫描近场微波显微镜（SNMM）轮廓应用所需的垂直侧壁的同时，已经获得了具有大于至少30μm的高度的微机械尖端。

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