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1. 发明授权

US09039784B2 Micro-structure particles for load bearing bone growth 有权
标题翻译：用于承载骨骼生长的微结构颗粒
公开(公告)号：US09039784B2
公开(公告)日：2015-05-26
申请号：US12510582
申请日：2009-07-28
申请人： Daniel P. Nicolella , Nitin Nitin , Heather S. Hanson , Kwai S. Chan
发明人： Daniel P. Nicolella , Nitin Nitin , Heather S. Hanson , Kwai S. Chan
IPC分类号： A61F2/28 , A61F2/30 , A61L27/40 , A61L27/44 , A61L27/46 , A61L27/12 , A61L27/10 , A61L27/04
CPC分类号： A61F2/28 , A61F2/2846 , A61F2/30734 , A61F2/30907 , A61F2002/2817 , A61F2002/30062 , A61F2002/30079 , A61F2002/30235 , A61F2002/30583 , A61F2002/30588 , A61F2002/30738 , A61F2002/30919 , A61F2002/3092 , A61F2210/0004 , A61F2210/0085 , A61F2210/009 , A61F2230/0069 , A61L27/042 , A61L27/10 , A61L27/12 , A61L27/40 , A61L27/446 , A61L27/46 , A61L2400/06 , A61L2400/12
摘要： The present disclosure relates to methods of facilitating bone growth. The method may include positioning a device around at least a portion of a bone exhibiting a defect, the device capable of retaining bone segments and micro-structured particles. The method may also include applying micro-structure particles within the device to the defect, wherein each of the micro-structure particles include at least one pore therein. In addition, the method may include aligning at least a portion of the micro-structure particles and applying a polymer to the particles and solidifying the polymer.
摘要翻译：本公开涉及促进骨生长的方法。该方法可以包括围绕呈现缺陷的骨骼的至少一部分定位装置，该装置能够保留骨段和微结构的颗粒。所述方法还可以包括将所述装置内的微结构颗粒应用于所述缺陷，其中所述微结构颗粒中的每一个在其中包括至少一个孔。此外，该方法可以包括对准至少一部分微结构颗粒并将聚合物施加到颗粒上并固化聚合物。

2. 发明申请

US20110208033A1 FRACTURE RISK ASSESSMENT 有权
标题翻译：破裂风险评估
公开(公告)号：US20110208033A1
公开(公告)日：2011-08-25
申请号：US12709309
申请日：2010-02-19
申请人： Daniel P. NICOLELLA , Todd L. BREDBENNER
发明人： Daniel P. NICOLELLA , Todd L. BREDBENNER
IPC分类号： A61B5/05
CPC分类号： A61B5/103 , A61B5/4509 , A61B8/483 , A61B8/5223
摘要： The present disclosure relates to a bone fracture risk assessment method and system. The method may include generating a volumetric model corresponding to a three-dimensional image of a bone structure for each bone structure in a set of bone structures. The method may further include defining a vector of variables for each bone structure. Each variable in the vector of variables may include a three-dimensional position of one of a number of volumetric vertices and at least one parameter associated with the one volumetric vertex. The method may include generating a set of individual vectors and performing variable reduction on the set of individual vectors. The method may further include determining a discriminator based at least in part on a result of the variable reduction.
摘要翻译：本发明涉及骨折风险评估方法和系统。该方法可以包括生成对应于一组骨结构中的每个骨结构的骨结构的三维图像的体积模型。该方法还可以包括为每个骨结构定义变量的向量。变量向量中的每个变量可以包括多个体积顶点中的一个的三维位置和与一个体积顶点相关联的至少一个参数。该方法可以包括生成一组单独的向量并且在该组个体向量上执行变量减少。该方法还可以包括至少部分地基于可变减少的结果来确定鉴别器。

3. 发明申请

US20110029026A1 Micro-Structure Particles For Load Bearing Bone Growth 有权
标题翻译：微结构颗粒负载轴承骨生长
公开(公告)号：US20110029026A1
公开(公告)日：2011-02-03
申请号：US12510582
申请日：2009-07-28
申请人： Daniel P. NICOLELLA , Nitin NITIN , Heather S. HANSON , Kwai S. CHAN
发明人： Daniel P. NICOLELLA , Nitin NITIN , Heather S. HANSON , Kwai S. CHAN
IPC分类号： A61B17/58
CPC分类号： A61F2/28 , A61F2/2846 , A61F2/30734 , A61F2/30907 , A61F2002/2817 , A61F2002/30062 , A61F2002/30079 , A61F2002/30235 , A61F2002/30583 , A61F2002/30588 , A61F2002/30738 , A61F2002/30919 , A61F2002/3092 , A61F2210/0004 , A61F2210/0085 , A61F2210/009 , A61F2230/0069 , A61L27/042 , A61L27/10 , A61L27/12 , A61L27/40 , A61L27/446 , A61L27/46 , A61L2400/06 , A61L2400/12
摘要： The present disclosure relates to methods of facilitating bone growth. The method may include positioning a device around at least a portion of a bone exhibiting a defect, the device capable of retaining bone segments and micro-structured particles. The method may also include applying micro-structure particles within the device to the defect, wherein each of the micro-structure particles include at least one pore therein. In addition, the method may include aligning at least a portion of the micro-structure particles and applying a polymer to the particles and solidifying the polymer.
摘要翻译：本公开涉及促进骨生长的方法。该方法可以包括围绕呈现缺陷的骨骼的至少一部分定位装置，该装置能够保留骨段和微结构的颗粒。所述方法还可以包括将所述装置内的微结构颗粒应用于所述缺陷，其中所述微结构颗粒中的每一个在其中包括至少一个孔。此外，该方法可以包括对准至少一部分微结构颗粒并将聚合物施加到颗粒上并固化聚合物。

4. 发明授权

US08725231B2 Fracture risk assessment 有权
标题翻译：骨折风险评估
公开(公告)号：US08725231B2
公开(公告)日：2014-05-13
申请号：US12709309
申请日：2010-02-19
申请人： Daniel P. Nicolella , Todd L. Bredbenner
发明人： Daniel P. Nicolella , Todd L. Bredbenner
IPC分类号： A61B5/05
CPC分类号： A61B5/103 , A61B5/4509 , A61B8/483 , A61B8/5223
摘要： The present disclosure relates to a bone fracture risk assessment method and system. The method may include generating a volumetric model corresponding to a three-dimensional image of a bone structure for each bone structure in a set of bone structures. The method may further include defining a vector of variables for each bone structure. Each variable in the vector of variables may include a three-dimensional position of one of a number of volumetric vertices and at least one parameter associated with the one volumetric vertex. The method may include generating a set of individual vectors and performing variable reduction on the set of individual vectors. The method may further include determining a discriminator based at least in part on a result of the variable reduction.
摘要翻译：本发明涉及骨折风险评估方法和系统。该方法可以包括生成对应于一组骨结构中的每个骨结构的骨结构的三维图像的体积模型。该方法还可以包括为每个骨结构定义变量的向量。变量向量中的每个变量可以包括多个体积顶点中的一个的三维位置和与一个体积顶点相关联的至少一个参数。该方法可以包括生成一组单独的向量并且在该组个体向量上执行变量减少。该方法还可以包括至少部分地基于可变减少的结果来确定鉴别器。

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