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1. 发明申请

US20120192134A1 User Guided Short Correction And Schematic Fix Visualization 审中-公开
标题翻译：用户引导短路校正和原理图修复可视化
公开(公告)号：US20120192134A1
公开(公告)日：2012-07-26
申请号：US13012791
申请日：2011-01-24
申请人： William Matthew Hogan , Phillip A. Brooks , Dae-Jin Kim , Kishore V. Kollu
发明人： William Matthew Hogan , Phillip A. Brooks , Dae-Jin Kim , Kishore V. Kollu
IPC分类号： G06F17/50
CPC分类号： G06F17/5081
摘要： Techniques for assisting a designer in correcting discrepancies identified in layout design data. A user interface may be provided listing identified shorts and relevant information related to those shorts. Still further, the user interface may allow a designer to selectively choose a subset of the identified shorts, and to designate or otherwise provide correction data for use to correct the shorts before performing a short isolation process on the selected shorts. Alternately or additionally a user interface may provide a designer with graphical images showing the correction that should be made by a designer to address an identified discrepancy in layout design data.
摘要翻译：协助设计师纠正布局设计数据中识别的差异的技术。可以提供用户界面列出所识别的短裤和与这些短裤相关的相关信息。此外，用户界面可以允许设计者选择性地选择识别的短裤的子集，并且在对所选择的短裤执行短隔离处理之前，指定或以其他方式提供用于校正短裤的校正数据。替代地或另外地，用户界面可以向设计者提供图形图像，其中显示了设计者应该进行的修正以解决布局设计数据中所识别的差异的校正。

2. 发明授权

US07680557B2 System for processing semiconductor substrate by using laser and method of the same 失效
标题翻译：使用激光加工半导体衬底的系统及其方法
公开(公告)号：US07680557B2
公开(公告)日：2010-03-16
申请号：US11575706
申请日：2004-09-22
申请人： Dae-Jin Kim , Je-Kil Ryu , Hyun-Jung Kim
发明人： Dae-Jin Kim , Je-Kil Ryu , Hyun-Jung Kim
IPC分类号： G06F19/00
CPC分类号： G05B19/41865 , H01L21/67294 , H01L27/10844 , Y02P90/20
摘要： The present invention provides a system for processing a semiconductor substrate using a laser beam, the system including: a storing unit storing a process control data set for a slot for loading the semiconductor substrate therein; a process controlling unit detecting identification information of the slot in which the semiconductor substrate is loaded, and reading the control data, which is set for the detected identification information, from the storing unit to control a process of the semiconductor substrate; and a substrate processing unit processing the semiconductor substrate on the basis of the read control data using the laser beam with a predetermined energy.
摘要翻译：本发明提供了一种使用激光束处理半导体衬底的系统，该系统包括：存储单元，用于存储用于将半导体衬底加载到其中的槽的过程控制数据组; 检测加载有半导体基板的槽的识别信息的处理控制单元，从存储单元读取对检测出的识别信息设定的控制数据，控制半导体基板的处理; 以及基板处理单元，其基于使用具有预定能量的激光束的读取控制数据来处理半导体基板。

3. 发明申请

US20090053246A1 IMMUNOGLOBULIN FC FRAGMENT MODIFIED BY NON-PEPTIDE POLYMER AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 有权
标题翻译：非肽聚合物修饰的免疫球蛋白FC片段和包含其的药物组合物
公开(公告)号：US20090053246A1
公开(公告)日：2009-02-26
申请号：US11910962
申请日：2005-04-28
申请人： Young Min Kim , Sung Min Bae , Dae Jin Kim , Dae Hae Song , Chang Ki Lim , Se Chang Kwon , Gwan Sun Lee
发明人： Young Min Kim , Sung Min Bae , Dae Jin Kim , Dae Hae Song , Chang Ki Lim , Se Chang Kwon , Gwan Sun Lee
IPC分类号： C07K19/00 , C07K16/00 , A61K39/44
CPC分类号： A61K47/6835 , A61K47/6811 , A61K47/6813 , C07K2317/52 , C07K2319/30
摘要： Disclosed are an Fc fragment modified by a non-peptide polymer, a pharmaceutical composition comprising the Fc fragment modified by the non-peptide polymer as a carrier, a complex of the Fc fragment and a drug via a linker and a pharmaceutical composition comprising such a complex. The Fc fragment modified by a non-peptide peptide according to the present invention lacks immunogenicity and effector functions. Due to these properties, the Fc fragment maintains the in vivo activity of a drug conjugated thereto in high levels, remarkably increases the serum half-life of the drug, and remarkably reduces the risk of inducing immune responses.
摘要翻译：公开了由非肽聚合物修饰的Fc片段，包含由作为载体的非肽聚合物修饰的Fc片段的药物组合物，Fc片段的复合物和通过接头的药物和包含这样的复杂。由本发明的非肽肽修饰的Fc片段缺乏免疫原性和效应子功能。由于这些性质，Fc片段以高水平维持与其结合的药物的体内活性，显着增加了药物的血清半衰期，并显着降低了诱导免疫应答的风险。

4. 发明申请

US20080124347A1 INSULINOTROPIC PEPTIDE CONJUGATE USING CARRIER SUBSTANCE 审中-公开
标题翻译：使用载体物质联合胰岛素
公开(公告)号：US20080124347A1
公开(公告)日：2008-05-29
申请号：US11747153
申请日：2007-05-10
申请人： Young Min Kim , Dae Jin Kim , Sung Min Bae , Chang Ki Lim , Se Chang Kwon , Gwan Sun Lee , Dae Hae Song , Young Hoon Kim
发明人： Young Min Kim , Dae Jin Kim , Sung Min Bae , Chang Ki Lim , Se Chang Kwon , Gwan Sun Lee , Dae Hae Song , Young Hoon Kim
IPC分类号： A61K39/395 , C07K14/62 , A61P3/10 , A61P3/04 , A61P15/00 , A61P9/00
CPC分类号： A61K47/68 , A61K47/6811 , A61K47/6813 , A61K47/6835 , C07K14/505 , C07K14/535 , C07K14/56 , C07K14/61 , C07K16/46 , C07K19/00 , C07K2317/52 , C07K2317/732 , C07K2317/734 , C07K2319/30
摘要： The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and a carrier substance, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half-life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs.
摘要翻译：本发明涉及具有改善的功效和稳定性的体内持续时间的促胰岛素肽缀合物，其包含彼此共价连接的促胰岛素肽，非肽聚合物和载体物质及其用途。本发明的促胰岛素肽缀合物具有保持较高的体内活性，并且血液半衰期显着增加，因此可以理想地用于开发各种肽药物的长效制剂。

5. 发明授权

US5570136A HDTV receiver 失效
标题翻译： HDTV接收机
公开(公告)号：US5570136A
公开(公告)日：1996-10-29
申请号：US421438
申请日：1995-04-12
申请人： Dae Jin Kim
发明人： Dae Jin Kim
IPC分类号： H04N5/44 , H04N5/455 , H04N5/50 , H04N5/46
CPC分类号： H04N5/4446 , H04N5/455 , H04N5/50 , H04N5/4401
摘要： An HDTV receiver is disclosed including a tuning portion for selecting one of a plurality of RF signals received, and converting a selected RF signal into an intermediate frequency signal; a demodulator/FPLL for demodulating the intermediate frequency signal output from the tuning portion into a baseband signal in which the frequency and phase are locked, and outputting an AFC signal; a first local oscillator for forming a frequency signal which can be varied from a reference frequency to a specific frequency, and outputting the thus-formed frequency signal to the demodulator/FPLL; and a VSB filter for VSB-filtering the baseband signal output from the demodulator/FPLL.
摘要翻译：公开了一种HDTV接收机，其包括用于选择所接收的多个RF信号中的一个的调谐部分，并将所选择的RF信号转换为中频信号; 解调器/ FPLL，用于将从调谐部分输出的中频信号解调为频率和相位被锁定的基带信号，并输出AFC信号; 用于形成可以从参考频率到特定频率变化的频率信号的第一本地振荡器，并将由此形成的频率信号输出到解调器/ FPLL; 以及用于对从解调器/ FPLL输出的基带信号进行VSB滤波的VSB滤波器。

6. 发明授权

US09944688B2 Non-peptidyl polymer-insulin multimer and method for producing the same 有权
公开(公告)号：US09944688B2
公开(公告)日：2018-04-17
申请号：US14123258
申请日：2012-06-01
申请人： Sung In Lim , Myung Hyun Jang , Dae Jin Kim , Sung Youb Jung , Se Chang Kwon
发明人： Sung In Lim , Myung Hyun Jang , Dae Jin Kim , Sung Youb Jung , Se Chang Kwon
IPC分类号： A61K47/48 , A61K38/28 , A61K47/30 , A61P3/10 , C07K14/62 , A61K47/60 , A61K47/52 , A61K47/69
CPC分类号： C07K14/62 , A61K38/28 , A61K47/52 , A61K47/60 , A61K47/6921
摘要： The present invention relates to a non-peptidyl polymer-insulin multimer comprising two or more of a non-peptidyl polymer-insulin conjugate prepared by linking a non-peptidyl polymer and insulin via a covalent bond, in which the conjugates are complexed with cobalt ion to form a multimer, a method and kit for the preparation of the multimer, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject.

7. 发明申请

US20140107023A1 NON-PEPTIDYL POLYMER-INSULIN MULTIMER AND METHOD FOR PRODUCING THE SAME 有权
标题翻译：非肽聚合物 - 胰岛素多元及其生产方法
公开(公告)号：US20140107023A1
公开(公告)日：2014-04-17
申请号：US14123258
申请日：2012-06-01
申请人： Sung In Lim , Myung Hyun Jang , Dae Jin Kim , Sung Youb Jung , Se Chang Kwon
发明人： Sung In Lim , Myung Hyun Jang , Dae Jin Kim , Sung Youb Jung , Se Chang Kwon
IPC分类号： C07K14/62
CPC分类号： C07K14/62 , A61K38/28 , A61K47/52 , A61K47/60 , A61K47/6921
摘要： The present invention relates to a non-peptidyl polymer-insulin multimer comprising two or more of a non-peptidyl polymer-insulin conjugate prepared by linking a non-peptidyl polymer and insulin via a covalent bond, in which the conjugates are complexed with cobalt ion to form a multimer, a method and kit for the preparation of the multimer, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject.
摘要翻译：本发明涉及一种非肽基聚合物 - 胰岛素多聚体，其包含通过共价键连接非肽基聚合物和胰岛素而制备的两种或多种非肽基聚合物 - 胰岛素结合物，其中缀合物与钴离子络合以形成多聚体的制备方法和试剂盒，用于预防或治疗糖尿病的药物组合物，其包含多聚体作为活性成分，以及通过向受试者施用该组合物来预防或治疗糖尿病的方法。

8. 发明申请

US20130028867A1 LONG-ACTING INTERFERON BETA FORMULATION USING IMMUNOGLOBULIN FRAGMENT 有权
标题翻译：使用免疫抑制蛋白片段的长效干扰素制剂
公开(公告)号：US20130028867A1
公开(公告)日：2013-01-31
申请号：US13638821
申请日：2011-04-04
申请人： Dae Jin Kim , Min Young Kim , Jin Sun Kim , Sung Hee Hong , Sung Youb Jung , Se Chang Kwon
发明人： Dae Jin Kim , Min Young Kim , Jin Sun Kim , Sung Hee Hong , Sung Youb Jung , Se Chang Kwon
IPC分类号： A61K38/21 , A61P25/28 , A61P37/06 , A61P35/00 , C07K14/565 , A61P31/12
CPC分类号： A61K38/215 , A61K47/68 , A61K47/6813 , A61K47/6835 , C07K14/565 , C07K19/00 , C07K2317/52 , C07K2317/732 , C07K2317/734 , C07K2319/30
摘要： The present invention relates to a long-acting interferon beta formulation having improved in vivo duration and stability, comprising an interferon beta conjugate that is prepared by covalently linking interferon beta with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting interferon beta formulation of the present invention maintains in vivo activity of interferon beta at a relatively high level and remarkably increases the serum half-life thereof, thereby being used for various diseases, for which interferon is efficacious.
摘要翻译：本发明涉及具有改善的体内持续时间和稳定性的长效型干扰素β制剂，其包含通过非肽基聚合物共价连接干扰素β与免疫球蛋白Fc区制备的干扰素β偶联物及其制备方法。本发明的长效干扰素β配方维持干扰素β的体内活性在相当高的水平，并显着提高其血清半衰期，从而被用于干扰素有效的各种疾病。

9. 发明授权

US08282340B2 Turbo-machine having bellows unit for automatic axial thrust control 有权
标题翻译：涡轮机具有用于自动轴向推力控制的波纹管单元
公开(公告)号：US08282340B2
公开(公告)日：2012-10-09
申请号：US12493353
申请日：2009-06-29
申请人： Dae-Jin Kim , Jinhan Kim
发明人： Dae-Jin Kim , Jinhan Kim
IPC分类号： F01D3/00
CPC分类号： F01D3/04 , F05D2240/52
摘要： A turbo-machine including a volute casing, a rotating shaft, an impeller, seals, an axial thrust control member and a bellows unit. The volute casing defines therein a fluid passage. The rotating shaft is rotatably provided in the volute casing. The impeller is coupled to the rotating shaft to draw fluid using centrifugal force. The seals are provided around the front and rear ends of the impeller to prevent leakage of fluid. The axial thrust control member is installed in the volute casing behind the impeller. The bellows unit includes the piston installed in the volute casing in a shape surrounding a circumferential outer surface of the axial thrust control member; and a bellows connected with one surface of the piston, the bellows having the predetermined elasticity; and an internal space, between the piston and the volute casing, isolated from the fluid drawn behind the impeller.
摘要翻译：涡轮机包括蜗壳，旋转轴，叶轮，密封件，轴向推力控制构件和波纹管单元。蜗壳在其中限定有流体通道。旋转轴可旋转地设置在蜗壳中。叶轮联接到旋转轴以使用离心力抽取流体。密封件围绕叶轮的前端和后端设置以防止流体泄漏。轴向推力控制构件安装在叶轮后面的蜗壳中。波纹管单元包括安装在蜗壳中的活塞，其形状围绕轴向推力控制构件的周向外表面; 以及与活塞的一个表面连接的波纹管，波纹管具有预定的弹性; 以及活塞和蜗壳之间的内部空间，与从叶轮后面吸取的流体分离。

10. 发明申请

US20100329845A1 TURBO-MACHINE HAVING BELLOWS UNIT FOR AUTOMATIC AXIAL THRUST CONTROL 有权
标题翻译：涡轮机具有自动轴向控制的BELLOWS单元
公开(公告)号：US20100329845A1
公开(公告)日：2010-12-30
申请号：US12493353
申请日：2009-06-29
申请人： Dae-Jin KIM , Jinhan Kim
发明人： Dae-Jin KIM , Jinhan Kim
IPC分类号： F01D3/04
CPC分类号： F01D3/04 , F05D2240/52
摘要： The turbo-machine of the present invention includes a volute casing, a rotating shaft, an impeller, seals, an axial thrust control member and a bellows unit. The volute casing defines therein a fluid passage. The rotating shaft is rotatably provided in the volute casing. The impeller is coupled to the rotating shaft to draw fluid using centrifugal force. The seals are provided around the front and rear ends of the impeller to prevent leakage of fluid. The axial thrust control member is installed in the volute casing behind the impeller. The bellows unit includes the piston installed in the volute casing in a shape surrounding a circumferential outer surface of the axial thrust control member; and a bellows connected with one surface of the piston, the bellows having the predetermined elasticity; and an internal space, between the piston and the volute casing, isolated from the fluid drawn behind the impeller.
摘要翻译：本发明的涡轮机包括蜗壳，旋转轴，叶轮，密封件，轴向推力控制构件和波纹管单元。蜗壳在其中限定有流体通道。旋转轴可旋转地设置在蜗壳中。叶轮联接到旋转轴以使用离心力抽取流体。密封件围绕叶轮的前端和后端设置以防止流体泄漏。轴向推力控制构件安装在叶轮后面的蜗壳中。波纹管单元包括安装在蜗壳中的活塞，其形状围绕轴向推力控制构件的周向外表面; 以及与活塞的一个表面连接的波纹管，波纹管具有预定的弹性; 以及活塞和蜗壳之间的内部空间，与从叶轮后面吸取的流体分离。

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