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1. 发明申请

US20130211534A1 PROSTHESIS 审中-公开
公开(公告)号：US20130211534A1
公开(公告)日：2013-08-15
申请号：US13695091
申请日：2011-04-28
申请人： Andrew Clive Taylor
发明人： Andrew Clive Taylor
IPC分类号： A61F2/34
CPC分类号： A61F2/34 , A61F2/30771 , A61F2/3094 , A61F2002/30161 , A61F2002/30306 , A61F2002/30841 , A61F2002/30957 , A61F2002/3412
摘要： A prosthesis comprising a plastics body and a plurality of barbed stakes extending from a bone-facing surface of said body; said stakes being sized and located to provide fixation on impaction
摘要翻译：一种假体，其包括塑料体和从所述主体的面向骨的表面延伸的多个有刺的桩; 所述赌注的大小和位置是为了提供冲击的固定

2. 发明授权

US08372155B2 Acetabular cup prosthesis and method of forming the prosthesis 有权
标题翻译：髋臼假体和假体的形成方法
公开(公告)号：US08372155B2
公开(公告)日：2013-02-12
申请号：US12572039
申请日：2009-10-01
申请人： Michael Antony Tuke , Andrew Clive Taylor
发明人： Michael Antony Tuke , Andrew Clive Taylor
IPC分类号： A61F2/32
CPC分类号： A61F2/34 , A61F2/0095 , A61F2002/30077 , A61F2002/30718 , A61F2002/3419 , A61F2002/3446 , A61F2210/0066 , A61F2310/00011 , B23P11/02 , B23P11/025 , Y10T29/49826 , Y10T29/49863 , Y10T29/49865 , Y10T29/49945
摘要： An acetabular cup prosthesis comprising an acetabular cup having a rim and comprising a metal band applied around the outer circumference of the acetabular cup prosthesis and adjacent to said rim.
摘要翻译：一种髋臼杯假体，其包括具有边缘的髋臼杯，并且包括围绕所述髋臼杯假体的外周并且邻近所述边缘施加的金属带。

3. 发明申请

US20120150310A1 PROSTHESIS 有权
公开(公告)号：US20120150310A1
公开(公告)日：2012-06-14
申请号：US13378593
申请日：2010-06-18
申请人： Andrew Clive Taylor , Michael Anthony Tuke , Jonathan Robert Thomas Jeffers
发明人： Andrew Clive Taylor , Michael Anthony Tuke , Jonathan Robert Thomas Jeffers
IPC分类号： A61F2/34
CPC分类号： A61F2/34 , A61F2/0095 , A61F2/4609 , A61F2002/30077 , A61F2002/30561 , A61F2002/30718 , A61F2002/3419 , A61F2002/3446 , A61F2002/465 , A61F2002/4681 , A61F2210/0066 , A61F2310/00179 , H01L33/501 , H01L33/508 , H01L2933/0041 , H05B33/10 , H05B33/145
摘要： An acetabular cup prosthesis having a rim and comprising a metal band applied around the outer circumference of the acetabular cup prosthesis and adjacent to said rim, said cup prosthesis additionally comprising one or more flanges extending from the metal band and being configured such that in use the or each flange connects the prosthesis to an impaction cup.
摘要翻译： 1.一种髋臼杯假体，其具有边缘并且包括围绕所述髋臼杯假体的外周并且邻近所述边缘施加的金属带，所述杯假体还包括从所述金属带延伸的一个或多个凸缘，并且被配置为使得在使用中或每个凸缘将假体连接到冲击杯。

4. 发明申请

US20090248170A1 PROSTHESIS 审中-公开
公开(公告)号：US20090248170A1
公开(公告)日：2009-10-01
申请号：US12394639
申请日：2009-02-27
申请人： Michael Antony Tuke , Andrew Clive Taylor
发明人： Michael Antony Tuke , Andrew Clive Taylor
IPC分类号： A61F2/36 , A61F2/28 , B29C39/22
CPC分类号： A61F2/3603 , A61B17/175 , A61F2/30771 , A61F2/3094 , A61F2002/30215 , A61F2002/30245 , A61F2002/30841 , A61F2002/30878 , A61F2002/3093 , A61F2002/30957 , A61F2230/0067 , A61F2230/0071 , A61F2310/00796 , A61F2310/0097
摘要： In a prosthesis and method for manufacturing the same, the prosthesis has an outer articulating surface and an inner bone-contacting surface. The inner surface of the prosthesis has at least one osteo-integration zone with one or more surface formations integrally cast with the wall of the prosthesis. In some instances the prosthesis may be a femoral head prosthesis. To manufacture the prosthesis, a mold is prepared and the prosthesis is cast to include the surface formations.
摘要翻译：在用于制造其的假体及其方法中，假体具有外关节表面和内骨接触表面。假体的内表面具有至少一个骨整合区，其中一个或多个表面形成物与假体的壁一体地铸造。在一些情况下，假体可以是股骨头假体。为了制造假体，制备模具并且假体被铸造以包括表面形成。

5. 发明申请

US20130231750A1 PROSTHESIS 有权
公开(公告)号：US20130231750A1
公开(公告)日：2013-09-05
申请号：US13576582
申请日：2011-02-03
申请人： Andrew Clive Taylor
发明人： Andrew Clive Taylor
IPC分类号： A61F2/34 , A61F2/28
CPC分类号： A61F2/34 , A61F2/28 , A61F2/30942 , A61F2/30965 , A61F2002/30028 , A61F2002/30062 , A61F2002/30324 , A61F2002/30594 , A61F2002/30733 , A61F2002/3092 , A61F2002/3097 , A61F2002/30971 , A61F2002/3487 , A61F2310/00796 , A61L27/18 , A61L27/54 , A61L27/56 , A61L2300/112 , A61L2300/608 , B29C45/16 , B29K2071/00 , B29K2511/06 , B29K2995/004 , B29L2009/00 , B29L2031/7532 , B33Y80/00 , C08L71/00
摘要： A prosthesis comprising: an inner layer (4) formed from a polyaryletherketone; a first outer layer (2a) adjacent to said inner layer formed from a porous polyaryletherketone, at least some of said pores having located therein material to promote osteointegration; and a second outer layer (2b) adjacent to said first outer layer formed from a porous polyaryletherketone, a portion of said pores being free of material to promote osteointegration. The invention also relates to a method of manufacture of the prosthesis. In an alternative arrangement, the prosthesis comprises: an inner layer formed from a polyaryletherketone; a first outer layer adjacent to said inner layer formed from a porous polyaryletherketone, at least some of said pores having located therein material to promote osteointegration having a crystallinity of from about 60% to about 90%; and a second outer layer adjacent to said first outer layer formed from a porous polyaryletherketone, at least a portion of said pores having located therein material to promote osteointegration having a crystallinity of less than about 50%.
摘要翻译：一种假体，包括：由聚芳醚酮形成的内层（4）邻近由多孔聚芳醚酮形成的所述内层的第一外层（2a），所述孔中的至少一些位于其中以促进骨整合的材料; 和邻近由多孔聚芳醚酮形成的所述第一外层的第二外层（2b），所述孔的一部分不含促进骨整合的材料。本发明还涉及一种制造假体的方法。在替代布置中，假体包括：由聚芳醚酮形成的内层; 与由所述多孔聚芳醚酮酮形成的所述内层相邻的第一外层，所述孔中的至少一些位于其中以促进结晶度为约60％至约90％的骨整合材料; 以及邻近由多孔聚芳醚酮形成的所述第一外层的第二外层，所述孔的至少一部分位于其中以促进结晶度小于约50％的骨整合。

6. 发明申请

US20100267064A1 METHODS FOR QUANTITATIVE TARGET DETECTION AND RELATED DEVICES AND SYSTEMS 有权
标题翻译：量化目标检测方法及相关设备和系统
公开(公告)号：US20100267064A1
公开(公告)日：2010-10-21
申请号：US12717402
申请日：2010-03-04
申请人： Emil P. Kartalov , Axel Scherer , Clive Taylor
发明人： Emil P. Kartalov , Axel Scherer , Clive Taylor
IPC分类号： G01N33/53 , G01N33/00 , C12M1/34 , G01N30/96
CPC分类号： G01N33/5306 , B01L3/502738 , B01L2300/0816 , B01L2300/0864 , B01L2300/088 , B01L2300/0883 , B01L2400/0475
摘要： Described herein is a method for detection of a target in a sample and related devices and systems.
摘要翻译：这里描述了用于检测样品中的目标物和相关装置和系统的方法。

7. 发明申请

US20090248168A1 PROSTHESIS 审中-公开
公开(公告)号：US20090248168A1
公开(公告)日：2009-10-01
申请号：US12394686
申请日：2009-02-27
申请人： Michael Antony Tuke , Andrew Clive Taylor
发明人： Michael Antony Tuke , Andrew Clive Taylor
IPC分类号： A61F2/34
CPC分类号： A61F2/34 , A61F2002/302 , A61F2002/30332 , A61F2002/30433 , A61F2002/30449 , A61F2002/305 , A61F2002/30563 , A61F2002/30581 , A61F2002/30583 , A61F2002/30612 , A61F2002/30695 , A61F2002/3448 , A61F2002/481 , A61F2210/0085 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2220/005 , A61F2230/0065 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00203 , A61F2310/00239 , A61F2310/00293 , A61F2310/00317
摘要： An acetabular cup prosthesis having a shell component, a liner component located within the shell component and a filling means located in a space between the shell component and the liner component.
摘要翻译：髋臼杯假体，其具有外壳部件，位于外壳部件内的衬垫部件和位于外壳部件和衬垫部件之间的空间中的填充装置。

8. 发明申请

US20090005877A1 PROSTHESIS 审中-公开
公开(公告)号：US20090005877A1
公开(公告)日：2009-01-01
申请号：US11769887
申请日：2007-06-28
申请人： Michael Antony Tuke , Andrew Clive Taylor
发明人： Michael Antony Tuke , Andrew Clive Taylor
IPC分类号： A61F2/32
CPC分类号： A61F2/34 , A61F2/0095 , A61F2/30767 , A61F2/4609 , A61F2/4637 , A61F2002/30225 , A61F2002/30405 , A61F2002/30462 , A61F2002/30612 , A61F2002/30682 , A61F2002/30718 , A61F2002/3411 , A61F2002/4681 , A61F2220/0025 , A61F2220/0075 , A61F2230/0069 , A61F2310/00011 , A61F2310/00179 , A61F2310/00203 , A61F2310/00239 , A61F2310/00317 , A61F2310/00796
摘要： A preassembled unit comprising an acetabular cup prosthesis and a cap covering the cup prosthesis, the cup comprising and outer shell and a liner located within the shell.
摘要翻译：一种预组装的单元，包括髋臼杯假体和覆盖所述杯假体的帽，所述杯包括外壳和位于所述外壳内的衬里。

9. 发明授权

US06869448B2 Prosthesis 有权
标题翻译：假体
公开(公告)号：US06869448B2
公开(公告)日：2005-03-22
申请号：US10341618
申请日：2003-01-14
申请人： Michael Anthony Tuke , Robert Michael Wozencroft , Andrew Clive Taylor
发明人： Michael Anthony Tuke , Robert Michael Wozencroft , Andrew Clive Taylor
IPC分类号： A61F2/38
CPC分类号： A61F2/389
摘要： A tibial prosthesis has a metal tray component (1) comprising a transverse member (3) with a peripheral upstanding rim (6) and a projecting stem (4). The upstanding rim (6) includes a posterior rim portion with an undercut lip forming a pair of recesses (7, 8) and an anterior rim portion with an open angled posterior surface portion (9) and a posteriorly projecting barbed portion (10). The prosthesis also includes a tibia insert (2) made of a plastics material which fits on the tibial implant (1) within the upstanding rim (6) and has on a posterior portion thereof a shaped contour (14, 15) adapted in use to fit snugly under the undercut lip and on an anterior portion thereof an anterior surface (13) having a taper angle substantially corresponding to the angle of the open angled posterior surface portion.
摘要翻译：胫骨假体具有金属托盘部件（1），其包括具有外围直立边缘（6）和突出柄（4）的横向构件（3）。直立边缘（6）包括后边缘部分，其具有形成一对凹口（7,8）的底切唇缘和具有开口角度后表面部分（9）的前边缘部分和一个向后突出的倒钩部分（10）。所述假体还包括由塑料材料制成的胫骨插入件（2），所述胫骨插入物（2）装配在所述直立边缘（6）内的所述胫骨植入物（1）上，并且在其后部具有适于使用的成形轮廓（14,15）紧贴在底切唇下方并且在其前部上具有基本上对应于开口角度后表面部分的角度的锥角的前表面（13）。

10. 发明授权

US08889416B2 Methods and devices for micro-isolation, extraction, and/or analysis of microscale components 有权
标题翻译：微量元件的微分离，提取和/或分析的方法和装置
公开(公告)号：US08889416B2
公开(公告)日：2014-11-18
申请号：US13010761
申请日：2011-01-20
申请人： Emil P. Kartalov , Darryl Shibata , Clive Taylor , Lawrence A. Wade
发明人： Emil P. Kartalov , Darryl Shibata , Clive Taylor , Lawrence A. Wade
IPC分类号： C12N5/02 , C12N5/00 , C12M1/34 , C12N13/00 , G01N33/543
CPC分类号： C12M23/16 , C12M23/12 , C12M23/22 , C12M25/04 , C12M25/14 , C12M35/02 , C12M37/04 , C12M47/04 , C12N13/00 , G01N33/54366
摘要： Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation apparatus described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation apparatus can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation apparatus can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation apparatus can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device. Also included are methods for selectively isolating cellular material using the apparatuses described herein, as are methods for biochemical analysis of individual regions of interest of cellular material using the devices described herein. Further included are methods of making masking arrays useful for the methods described herein.
摘要翻译：本文提供用于微生物细胞材料的微分离的装置和方法。所描述的微分离装置可以包括保护感兴趣区域以防止DNA破坏照明的光掩模。微型隔离装置还可以包括感光材料，该感光材料在照射之后界定存取孔，随后显影感光材料。微隔离装置还可以包括腔室微流体装置，其包括通道，其提供对感光材料中限定的孔的通路。微型隔离装置可以包括腔室微流体装置，其无感光材料中限定的通路孔，阀门通过微流体装置的通道控制气体或液体的流动。还包括使用本文所述装置选择性分离细胞材料的方法，以及使用本文所述装置的细胞材料的各个感兴趣区域的生物化学分析的方法。还包括制备用于本文所述方法的掩蔽阵列的方法。

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