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1. 发明授权

US6092000A Method for maximizing the throughput of a multiple-step workstation in a plant 失效
标题翻译：用于最大化工厂中多步骤工作站的吞吐量的方法
公开(公告)号：US6092000A
公开(公告)日：2000-07-18
申请号：US958968
申请日：1997-10-28
申请人： Chun-Yen Kuo , Yirn-Sheng Pan , Horng-Huei Tseng
发明人： Chun-Yen Kuo , Yirn-Sheng Pan , Horng-Huei Tseng
IPC分类号： G05B19/418 , G06F19/00
CPC分类号： G05B19/41865 , G05B2219/32294 , G05B2219/45031 , Y02P90/20
摘要： A method for maximizing the throughput of a multiple-step workstation in a plant includes forming an interrecipe delay time array having rows of delay times for a plurality of lots L.sub.n with a plurality of recipes R.sub.n caused by a lot L.sub.n-1 with a recipe R.sub.n-1 for n=1 to a, and columns of delay times for a recipe LR.sub.n caused by a plurality of recipes LR.sub.n-1 for n=1 to a. An array of feasible recipe-to-recipe sequences S(n,m) is then formed having rows of feasible recipe-to-recipe sequences for the lot L.sub.n in a plurality of orders O.sub.m for m=1 to a, and columns of feasible recipe-to-recipe sequences for a plurality of lots L.sub.n in the order O.sub.m for m=1 to a. A recipe-to-recipe sequence in an order that is selected to be processed has a value of 1, and all other sequences in that order have a value of 0. Subsequently, a lot-recipe mapping array is formed that maps a recipe to be used for each lot. An objective function and a constraint function are formed, and may be typical linear programming functions. The objective function is solved subject to the constraint function using an integer programming solver to yield solution sets of recipe-to-recipe sequences having a value of 1. Finally, an optimal process of recipe-to-recipe sequences is formed from lots with minimum total delay times for orders O.sub.1 through O.sub.m.
摘要翻译：用于最大化工厂中的多步骤工作站的吞吐量的方法包括形成具有多个批次Ln的具有多个批次Ln的延迟时间行的配对间延迟时间阵列，其具有由具有配方Rn的批次Ln-1引起的多个配方Rn 对于n = 1到a，-1表示由n = 1到a的多个配方LRn-1引起的配方LRn的延迟时间列。然后形成一系列可行的配方到配方序列S（n，m），其具有针对m = 1至a的多个订单量Om中的批次Ln的可行配方到配方序列的行，以及可行的列对于m = 1到a，多个批次Ln的配方到配方序列的顺序为Om。选择要处理的顺序的配方到配方序列的值为1，并且该顺序中的所有其他序列的值为0.随后，形成批次配方映射数组，将配方映射到用于每一批。形成目标函数和约束函数，可以是典型的线性规划函数。目标函数使用整数规划求解器解决约束函数，以产生具有值为1的配方到配方序列的解集。最后，从最小的批次形成配方到配方序列的最佳过程订单O1至Om的总延迟时间。

2. 发明申请

US20100285558A1 Apparatus and Method for High-Throughput Micro-Cell Culture with Mechanical Stimulation 审中-公开
标题翻译：用于机械刺激的高通量微细胞培养的装置和方法
公开(公告)号：US20100285558A1
公开(公告)日：2010-11-11
申请号：US12437803
申请日：2009-05-08
申请人： Min-Hsien Wu , Wei-Chung Pan , Chun-Yen Kuo
发明人： Min-Hsien Wu , Wei-Chung Pan , Chun-Yen Kuo
IPC分类号： C12N13/00 , C12M1/00
CPC分类号： C12N13/00 , C12M29/10 , C12M29/14 , C12M35/04
摘要： A method for high-throughput micro-cell culture with mechanical stimulation includes providing cells on a membrane, supplying a culture medium to the cells, and vibrating the membrane by exerting and varying a fluid pressure on the membrane such that the cells are mechanically stimulated through the membrane.An apparatus for high-throughput micro-cell culture with mechanical stimulation includes a cell culture vessel and a fluid pressure supply unit. The cell culture vessel has the membrane, a culture medium chamber, and a pressure chamber. The fluid pressure supply unit is connected fluidly to the pressure chamber, and has a fluid pressure supply device and a control device. The membrane vibrates when the fluid pressure in the pressure chamber is varied. The apparatus provides mechanical stimulation to the cultured cells in a controllable manner.
摘要翻译：具有机械刺激的高通量微细胞培养的方法包括在膜上提供细胞，向细胞提供培养基，并通过施加和改变膜上的流体压力来振动膜，使得细胞通过机械刺激通过膜。用于具有机械刺激的高通量微细胞培养的装置包括细胞培养容器和流体压力供应单元。细胞培养容器具有膜，培养基室和压力室。流体压力供给单元与压力室流体连接，具有流体压力供给装置和控制装置。当压力室中的流体压力变化时，膜振动。该装置以可控的方式向培养的细胞提供机械刺激。

3. 发明授权

US5940298A Capacity loss control method for preventative maintenance in IC plant 失效
标题翻译：集成电路预防性维护的容量损失控制方法
公开(公告)号：US5940298A
公开(公告)日：1999-08-17
申请号：US852976
申请日：1997-05-07
申请人： Yirn-Sheng Pan , Horng-Huei Tseng , Chun-Yen Kuo , Jeng-Tyan Lin
发明人： Yirn-Sheng Pan , Horng-Huei Tseng , Chun-Yen Kuo , Jeng-Tyan Lin
IPC分类号： G05B19/418 , G06Q10/06 , G06F19/00
CPC分类号： G06Q10/06 , G05B19/4184 , G06Q10/0639 , Y02P90/14 , Y02P90/20
摘要： A process is provided for operating a manufacturing plant subsequent to preventative maintenance steps. The steps of the process are the following. Provide a data processing system having memory means for data storage. Provide central processing means for (a) accessing data from the memory means, (b) receiving data from data input means and (c) supplying data to the memory means. Provide Preventive Maintenance (PM) Duration (D) data to the data processing system. Calculate the effect of a PM schedule upon the efficiency of operation of the plant. Provide a new PM schedule to improve the efficiency of operation of the plant.
摘要翻译：提供了用于在预防性维护步骤之后操作制造工厂的过程。该过程的步骤如下。提供具有用于数据存储的存储装置的数据处理系统。提供用于（a）从存储装置访问数据的中央处理装置，（b）从数据输入装置接收数据，（c）向存储装置提供数据。向数据处理系统提供预防性维护（PM）持续时间（D）数据。计算PM时间表对工厂运行效率的影响。提供新的PM计划，以提高工厂的运行效率。

4. 发明申请

US20120276622A1 APPARATUS AND METHOD FOR HIGH-THROUGHPUT MICRO-CELL CULTURE WITH MECHANICAL STIMULATION 审中-公开
标题翻译：用于机械刺激的高通量微细胞培养的装置和方法
公开(公告)号：US20120276622A1
公开(公告)日：2012-11-01
申请号：US13541743
申请日：2012-07-04
申请人： Min-Hsien Wu , Wei-Chung Pan , Chun-Yen Kuo
发明人： Min-Hsien Wu , Wei-Chung Pan , Chun-Yen Kuo
IPC分类号： C12M1/02
CPC分类号： C12N13/00 , C12M25/02 , C12M29/10 , C12M29/14 , C12M35/04
摘要： A method and apparatus for high-throughput micro-cell culture with mechanical stimulation is disclosed. In one embodiment, the apparatus includes a cell culture vessel and a fluid pressure supply unit. The cell culture vessel has a membrane, a culture medium chamber, and a pressure chamber; and the fluid pressure supply unit that has a fluid pressure supply device and a control device is connected fluidly to the pressure chamber. When the fluid pressure in the pressure chamber changes, the membrane vibrates accordingly to generate a mechanical stimulation to the cultured cells in a controllable manner. In another embodiment, the control device can be an electro-magnetic valve.
摘要翻译：公开了一种用于机械刺激的高通量微细胞培养的方法和装置。在一个实施例中，该装置包括细胞培养容器和流体压力供应单元。细胞培养容器具有膜，培养基室和压力室; 并且具有流体压力供给装置和控制装置的流体压力供给单元流体地连接到压力室。当压力室中的流体压力改变时，膜相应地振动，以可控的方式对培养的细胞产生机械刺激。在另一个实施例中，控制装置可以是电磁阀。

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