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1. 发明授权

US08308928B2 Thrombosis filter with cover layer 有权
标题翻译：具有覆盖层的血栓滤过
公开(公告)号：US08308928B2
公开(公告)日：2012-11-13
申请号：US12438635
申请日：2007-08-24
申请人： Eckhard Quandt , Christiane Zamponi , Clemens Schmutz
发明人： Eckhard Quandt , Christiane Zamponi , Clemens Schmutz
IPC分类号： C25D1/00 , A61L33/00 , B29C37/02
CPC分类号： A61L31/022 , A61F2/01 , A61F2002/018 , A61F2230/005 , A61F2230/008 , A61L31/088 , A61L31/14
摘要： A method is provided for applying a cover layer (9) to a net structure (4) to be used for medical purposes, in particular a thrombosis filter. The net structure (4) is applied to a planar substrate (1) that covers openings (5) of the net structure on one side, wherein the openings (5) across the uncovered side are filled with a sacrificial material (7), in particular copper. The net structure (4) is lifted from the substrate (1). A cover layer (9) is deposited on the surface previously covered by the substrate, and the sacrificial material (7) is removed.
摘要翻译：提供了一种将覆盖层（9）施加到用于医疗目的的网状结构（4）的方法，特别是血栓形成过滤器。网结构（4）被施加到覆盖一侧的网状结构的开口（5）的平面基板（1），其中穿过未覆盖侧的开口（5）填充有牺牲材料（7），其中特殊的铜。网结构（4）从衬底（1）提起。覆盖层（9）沉积在由衬底预先覆盖的表面上，并去除牺牲材料（7）。

2. 发明申请

US20090127226A1 PROCESS FOR PRODUCING SELF-SUPPORTING TITANIUM AND NICKEL LAYERS 审中-公开
标题翻译：生产自支撑钛和镍层的方法
公开(公告)号：US20090127226A1
公开(公告)日：2009-05-21
申请号：US11912278
申请日：2006-04-24
申请人： Eckhard Quandt , Holger Rumpf , Christiane Zamponi
发明人： Eckhard Quandt , Holger Rumpf , Christiane Zamponi
IPC分类号： B44C1/22 , A61F2/82 , A61B17/58 , A61F2/01
CPC分类号： C23C14/0005 , A61F2/0077 , A61F2/01 , A61F2/82 , A61F2210/0014 , A61F2240/001 , A61F2310/00407 , A61F2310/00461 , A61L27/306 , A61L2400/16 , C23C14/165 , C23F1/26 , C23F1/28
摘要： A process for producing a self-supporting layer made of a titanium and nickel alloy with superelastic and/or shape memory properties has the following steps: a substrate entirely or at least mainly made of silicon is provided, a layer of said alloy is applied to a surface of the substrate, the substrate with the desired form is cut out of a wafer or formed by a wafer with the desired form; at least some zones of the lateral surfaces of the substrate adjoining the zones of the surface of the substrate which receive the layer are subjected to an etching process; a layer of said alloy is applied to the surface of the substrate; and the substrate is removed from the applied layer. Also disclosed is a substrate suitable for carrying out the process and an object, in particular an implant, comprising at least one layer produced by this process.
摘要翻译：制造具有超弹性和/或形状记忆特性的由钛和镍合金制成的自支撑层的方法具有以下步骤：提供完全或至少主要由硅制成的基底，将所述合金层施加到衬底的表面，具有所需形式的衬底从晶片切割或由具有所需形式的晶片形成; 基板邻接接触层的基板的表面的区域的侧表面的至少一些区域进行蚀刻处理; 将所述合金层施加到基板的表面; 并且从所施加的层去除衬底。还公开了适用于实施该方法的基材，以及包含至少一个通过该方法生产的层的物体，特别是植入物。

3. 发明申请

US20130199713A1 METHOD FOR PRODUCING A MEDICAL DEVICE 有权
标题翻译：生产医疗器械的方法
公开(公告)号：US20130199713A1
公开(公告)日：2013-08-08
申请号：US13695136
申请日：2011-04-28
申请人： Christiane Zamponi , Rodrigo Lima De Miranda
发明人： Christiane Zamponi , Rodrigo Lima De Miranda
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61F2240/001
摘要： A method for producing a medical device with a lattice structure, connected at least in some areas to a cover. The lattice structure is arranged on a substrate via the side to be connected to the cover, the lattice structure has the side arranged on the substrate pressed at least partially into the substrate, the lattice structure is coated with a first layer of a sacrificial material. At least some of the interstices of the lattice structure are covered by the first layer, and the first layer with the lattice structure on the side to be connected to the cover forms a substantially closed surface, the substrate is removed, making the side of the lattice structure accessible for connection to the cover. A second layer for forming the cover is applied to the side of the lattice structure previously pressed into the substrate, and the sacrificial material is removed.
摘要翻译：一种用于生产具有格子结构的医疗装置的方法，至少在一些区域连接到盖。晶格结构经由待连接到盖的一侧设置在基板上，格子结构具有被布置在基板上的至少部分地压入基板的一侧，栅格结构涂覆有第一层牺牲材料。晶格结构的至少一些间隙被第一层覆盖，并且具有连接到盖的侧面上的格子结构的第一层形成基本封闭的表面，基板被去除，使得网格结构可以连接到盖子。用于形成盖的第二层被施加到先前压入基板的格子结构的一侧，并且去除牺牲材料。

4. 发明申请

US20100009142A1 METHOD FOR THE PRODUCTION OF STRUCTURED LAYERS OF TITANIUM AND NICKEL 失效
标题翻译：生产钛和镍的结构层的方法
公开(公告)号：US20100009142A1
公开(公告)日：2010-01-14
申请号：US12306646
申请日：2007-06-27
申请人： Eckhard Quandt , Clemens Schmutz , Christiane Zamponi
发明人： Eckhard Quandt , Clemens Schmutz , Christiane Zamponi
IPC分类号： B32B3/02 , C23F1/02 , G03F7/20 , C23C14/34
CPC分类号： C23C14/0005 , A61L27/06 , A61L31/022 , B81B2201/06 , B81C99/008 , Y10T428/24917
摘要： A method for the production of a structured metal layer (7) made from an alloy composed of titanium and nickel includes the following process steps: a sacrificial layer composite (3) is provided, which comprises a second sacrificial layer (2) applied onto a first sacrificial layer (1), the first sacrificial layer (1) is subjected for the purpose of structuring to a wet-chemical etching process in such a manner that undercutting of the sacrificial layer (1) occurs, a metal layer (7) of the alloy is applied indirectly or directly to the structured sacrificial layer composite (3). The first sacrificial layer (1) is at a greater distance from the metal layer (7). The second sacrificial layer (2) facing the metal layer (7) to be deposited is subjected to a dry etching process prior to wet-chemical etching of the first sacrificial layer (1) so that the second sacrificial layer (2) is provided with a structure that corresponds to the desired structure of the metal layer (7). The invention further relates to an object, particularly a stent or an implant, which comprises at least one metal layer (7) that is produced by applying the method for the production of the structured metal layer (7).
摘要翻译：制造由钛和镍组成的合金制成的结构金属层（7）的方法包括以下工艺步骤：提供牺牲层复合材料（3），该牺牲层复合材料（3）包括第二牺牲层（2）第一牺牲层（1），第一牺牲层（1）的目的是以如下方式进行湿法化学蚀刻工艺的构造：使牺牲层（1）发生底切，金属层（7）该合金间接或直接施加到结构化牺牲层复合材料（3）上。第一牺牲层（1）距离金属层（7）更大的距离。在第一牺牲层（1）的湿化学蚀刻之前，面对要沉积的金属层（7）的第二牺牲层（2）进行干蚀刻处理，使得第二牺牲层（2）设置有对应于金属层（7）的所需结构的结构。本发明还涉及一种物体，特别是支架或植入物，其包括通过施加用于生产结构化金属层（7）的方法而产生的至少一个金属层（7）。

5. 发明授权

US09192489B2 Method for producing a medical device 有权
标题翻译：医疗器械的制造方法
公开(公告)号：US09192489B2
公开(公告)日：2015-11-24
申请号：US13695136
申请日：2011-04-28
申请人： Christiane Zamponi , Rodrigo Lima De Miranda
发明人： Christiane Zamponi , Rodrigo Lima De Miranda
IPC分类号： B29C65/48 , B29C65/52 , B32B37/10 , B32B37/12 , B32B38/10 , B32B43/00 , A61F2/82
CPC分类号： A61F2/82 , A61F2240/001
摘要： A method for producing a medical device with a lattice structure, connected at least in some areas to a cover. The lattice structure is arranged on a substrate via the side to be connected to the cover, the lattice structure has the side arranged on the substrate pressed at least partially into the substrate, the lattice structure is coated with a first layer of a sacrificial material. At least some of the interstices of the lattice structure are covered by the first layer, and the first layer with the lattice structure on the side to be connected to the cover forms a substantially closed surface, the substrate is removed, making the side of the lattice structure accessible for connection to the cover. A second layer for forming the cover is applied to the side of the lattice structure previously pressed into the substrate, and the sacrificial material is removed.
摘要翻译：一种用于生产具有格子结构的医疗装置的方法，至少在一些区域连接到盖。晶格结构经由待连接到盖的一侧设置在基板上，格子结构具有被布置在基板上的至少部分地压入基板的一侧，栅格结构涂覆有第一层牺牲材料。晶格结构的至少一些间隙被第一层覆盖，并且具有连接到盖的侧面上的格子结构的第一层形成基本封闭的表面，基板被去除，使得网格结构可以连接到盖子。用于形成盖的第二层被施加到先前压入基板的格子结构的一侧，并且去除牺牲材料。

6. 发明授权

US08758636B2 Method for producing a medical functional element comprising a selfsupporting lattice structure 有权
标题翻译：包括自支撑晶格结构的医用功能元件的制造方法
公开(公告)号：US08758636B2
公开(公告)日：2014-06-24
申请号：US13322998
申请日：2010-05-28
申请人： Eckhard Quandt , Christiane Zamponi , Rodrigo Lima De Miranda
发明人： Eckhard Quandt , Christiane Zamponi , Rodrigo Lima De Miranda
IPC分类号： C03C15/00 , B44C1/22 , H01L21/027 , H01L21/768 , H05K3/04
CPC分类号： H01L21/0271 , A61F2/82 , A61F2240/001 , A61L27/06 , A61L27/50 , H01L21/7688 , H05K3/048
摘要： A method for producing a medical functional element having a self-supporting lattice structure which has interconnected webs. The method applies a first layer to the substrate layer, the first layer is structured by an etching process, the structured first layer is under-cut of a wet chemical etching process acting on the substrate layer, the substrate layer is removed in order to form the self-supporting lattice structure, a web constructional layer is applied to the first layer. The method is distinguished by the forming the first web attachment layer which has a smaller layer thickness than the web constructional layer and is intimately bonded to the web constructional layer in such a way that the web attachment layer, together with the web constructional layer, forms the webs of the self-supporting lattice structure.
摘要翻译：一种具有互连网的具有自支撑格子结构的医用功能元件的制造方法。该方法将第一层施加到衬底层，第一层通过蚀刻工艺构成，结构化第一层被作为衬底层的湿化学蚀刻工艺进行底切，衬底层被去除以形成自支撑格子结构，将网状结构层施加到第一层。该方法的特征在于形成第一纤维网附着层，其具有比纤维网结构层更薄的层厚度，并且以这样的方式紧密地结合到幅材结构层，使得幅材附着层与纤维网结构层一起形成自支撑晶格结构的网。

7. 发明授权

US08338311B2 Method for the production of structured layers of titanium and nickel 失效
标题翻译：用于生产钛和镍结构层的方法
公开(公告)号：US08338311B2
公开(公告)日：2012-12-25
申请号：US12306646
申请日：2007-06-27
申请人： Eckhard Quandt , Clemens Schmutz , Christiane Zamponi
发明人： Eckhard Quandt , Clemens Schmutz , Christiane Zamponi
IPC分类号： H01L21/302
CPC分类号： C23C14/0005 , A61L27/06 , A61L31/022 , B81B2201/06 , B81C99/008 , Y10T428/24917
摘要： A method for the production of a structured metal layer (7) made from an alloy composed of titanium and nickel includes the following process steps: a sacrificial layer composite (3) is provided, which comprises a second sacrificial layer (2) applied onto a first sacrificial layer (1), the first sacrificial layer (1) is subjected for the purpose of structuring to a wet-chemical etching process in such a manner that undercutting of the sacrificial layer (1) occurs, a metal layer (7) of the alloy is applied indirectly or directly to the structured sacrificial layer composite (3). The first sacrificial layer (1) is at a greater distance from the metal layer (7). The second sacrificial layer (2) facing the metal layer (7) to be deposited is subjected to a dry etching process prior to wet-chemical etching of the first sacrificial layer (1) so that the second sacrificial layer (2) is provided with a structure that corresponds to the desired structure of the metal layer (7). The invention further relates to an object, particularly a stent or an implant, which comprises at least one metal layer (7) that is produced by applying the method for the production of the structured metal layer (7).
摘要翻译：制造由钛和镍组成的合金制成的结构金属层（7）的方法包括以下工艺步骤：提供牺牲层复合材料（3），该牺牲层复合材料（3）包括第二牺牲层（2）第一牺牲层（1），第一牺牲层（1）的目的是以如下方式进行湿法化学蚀刻工艺的构造：使牺牲层（1）发生底切，金属层（7）该合金间接或直接施加到结构化牺牲层复合材料（3）上。第一牺牲层（1）距离金属层（7）更大的距离。在第一牺牲层（1）的湿化学蚀刻之前，面对要沉积的金属层（7）的第二牺牲层（2）进行干蚀刻处理，使得第二牺牲层（2）设置有对应于金属层（7）的所需结构的结构。本发明还涉及一种物体，特别是支架或植入物，其包括通过施加用于生产结构化金属层（7）的方法而产生的至少一个金属层（7）。

8. 发明申请

US20120125888A1 METHOD FOR PRODUCING A MEDICAL FUNCTIONAL ELEMENT COMPRISING A SELFSUPPORTING LATTICE STRUCTURE 有权
标题翻译：生产包含消费结构的医疗功能元件的方法
公开(公告)号：US20120125888A1
公开(公告)日：2012-05-24
申请号：US13322998
申请日：2010-05-28
申请人： Eckhard Quandt , Christiane Zamponi , Rodrigo Lima De Miranda
发明人： Eckhard Quandt , Christiane Zamponi , Rodrigo Lima De Miranda
IPC分类号： B32B37/02 , B32B38/10
CPC分类号： H01L21/0271 , A61F2/82 , A61F2240/001 , A61L27/06 , A61L27/50 , H01L21/7688 , H05K3/048
摘要： A method for producing a medical functional element having a self-supporting lattice structure which has interconnected webs. The method applies a first layer to the substrate layer, the first layer is structured by an etching process, the structured first layer is under-cut of a wet chemical etching process acting on the substrate layer, the substrate layer is removed in order to form the self-supporting lattice structure, a web constructional layer is applied to the first layer. The method is distinguished by the forming the first web attachment layer which has a smaller layer thickness than the web constructional layer and is intimately bonded to the web constructional layer in such a way that the web attachment layer, together with the web constructional layer, forms the webs of the self-supporting lattice structure.
摘要翻译：一种具有互连网的具有自支撑格子结构的医用功能元件的制造方法。该方法将第一层施加到衬底层，第一层通过蚀刻工艺构成，结构化第一层被作为衬底层的湿化学蚀刻工艺进行底切，衬底层被去除以形成自支撑格子结构，将网状结构层施加到第一层。该方法的特征在于形成第一纤维网附着层，其具有比纤维网结构层更薄的层厚度，并且以这样的方式紧密地结合到幅材结构层，使得幅材附着层与纤维网结构层一起形成自支撑晶格结构的网。

9. 发明申请

US20100145380A1 THROMBOSIS FILTER WITH COVER LAYER 有权
标题翻译：具有覆盖层的THROMBOSIS过滤器
公开(公告)号：US20100145380A1
公开(公告)日：2010-06-10
申请号：US12438635
申请日：2007-08-24
申请人： Eckhard Quandt , Christiane Zamponi , Clemens Schmutz
发明人： Eckhard Quandt , Christiane Zamponi , Clemens Schmutz
IPC分类号： A61F2/01 , B05D1/38 , B32B37/04 , C23C14/34
CPC分类号： A61L31/022 , A61F2/01 , A61F2002/018 , A61F2230/005 , A61F2230/008 , A61L31/088 , A61L31/14
摘要： A method is provided for applying a cover layer (9) to a net structure (4) to be used for medical purposes, in particular a thrombosis filter. The net structure (4) is applied to a planar substrate (1) that covers openings (5) of the net structure on one side, wherein the openings (5) across the uncovered side are filled with a sacrificial material (7), in particular copper. The net structure (4) is lifted from the substrate (1). A cover layer (9) is deposited on the surface previously covered by the substrate, and the sacrificial material (7) is removed.
摘要翻译：提供了一种将覆盖层（9）施加到用于医疗目的的网状结构（4）的方法，特别是血栓形成过滤器。网结构（4）被施加到覆盖一侧的网状结构的开口（5）的平面基板（1），其中穿过未覆盖侧的开口（5）填充有牺牲材料（7），其中特殊的铜。网结构（4）从衬底（1）提起。覆盖层（9）沉积在由衬底预先覆盖的表面上，并去除牺牲材料（7）。

10. 发明申请

US20100049310A1 METHOD FOR COATING A STENT 审中-公开
标题翻译：涂层手段的方法
公开(公告)号：US20100049310A1
公开(公告)日：2010-02-25
申请号：US12279647
申请日：2007-02-15
申请人： Eckhard Quandt , Holger Rumpf , Christiane Zamponi , Michael Koch
发明人： Eckhard Quandt , Holger Rumpf , Christiane Zamponi , Michael Koch
IPC分类号： A61F2/06 , B05D7/00
CPC分类号： A61L27/30 , A61F2/91 , A61L31/082 , C23C30/00
摘要： Method for applying a coating layer to a tubular intraluminal implant, in particular to a vascular support (stent), where the surface of the implant is perforated by a plurality of apertures, and where the coating layer is produced by deposition of material onto the surface of the implant. The implant is first pushed onto a cylindrical holder 4, a sacrificial material, in particular copper, is then deposited onto the surface of the implant until the deposited sacrificial material almost entirely fills the apertures, the coating layer is then deposited onto the surface of the implant provided with sacrificial material, and then the cylindrical holder 4 and the sacrificial material situated in the apertures 3 are removed.
摘要翻译：将涂层施加到管状腔内植入物，特别是血管支架（支架）上的方法，其中植入物的表面被多个孔打孔，并且其中通过将材料沉积到表面上而产生涂层的植入物。首先将植入物推到圆柱形保持器4上，然后将牺牲材料，特别是铜沉积到植入物的表面上，直到沉积的牺牲材料几乎完全填充孔，然后将涂层沉积到设置有牺牲材料的植入物，然后移除位于孔3中的圆柱形保持器4和牺牲材料。

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