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1. 发明授权

US10086044B2 Heparan sulphate which binds BMP2 有权
公开(公告)号：US10086044B2
公开(公告)日：2018-10-02
申请号：US13062364
申请日：2009-09-11
申请人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
发明人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC分类号： A61K31/727 , C08B37/00 , C08B37/10 , A61L27/54 , A61K38/18 , A61L27/36 , B01D15/38 , C12N5/0775 , A61K31/737 , A61K35/28 , A61L27/26 , A61L27/38 , A61K35/12
摘要： The invention relates to heparan sulphate GAGs obtained by affinity chromatography using the heparin-binding domain of BMP2. The GAGs were obtained from osteoblast extracellular matrix and from a commercially available heparan sulfate (Celsus HS).

2. 发明授权

US09344249B2 Method for a transmitter for a multi-channel communication system for sending real-time data 有权
标题翻译：用于发送实时数据的多通道通信系统的发射机的方法
公开(公告)号：US09344249B2
公开(公告)日：2016-05-17
申请号：US14110493
申请日：2012-04-05
申请人： Christian Dombrowski , James Gross
发明人： Christian Dombrowski , James Gross
IPC分类号： H04L5/00 , H04L1/08 , H04L1/00 , H04L1/04 , H04B1/74 , H04L1/06
CPC分类号： H04L5/0053 , H04B1/74 , H04L1/0009 , H04L1/04 , H04L1/0625 , H04L1/08 , H04L5/003
摘要： The invention discloses a method for sending real-time sensitive data using a transmitter for a multi channel communication system, wherein the communication system has n sub-channels, wherein n is greater than 1, wherein the sub-channels are spatially different and/or the sub-channels have different frequencies. The method has the steps of receiving information about the channel state of the n sub-channels, receiving information about the number of statistically independent sub-channels m, wherein m is less than or equal to n, and receiving data intended to be sent.
摘要翻译：本发明公开了一种使用多通道通信系统的发射机发送实时敏感数据的方法，其中通信系统具有n个子信道，其中n大于1，其中子信道在空间上不同和/或子通道具有不同的频率。该方法具有以下步骤：接收关于n个子信道的信道状态的信息，接收关于统计上独立的子信道m的数量的信息，其中m小于或等于n，并且接收要发送的数据。

3. 发明申请

US20110165132A1 Heparan Sulphate Which Binds BMP2 审中-公开
标题翻译：硫酸氢硫酸盐结合BMP2
公开(公告)号：US20110165132A1
公开(公告)日：2011-07-07
申请号：US13062364
申请日：2009-09-11
申请人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
发明人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC分类号： A61K35/32 , C07K14/00 , A61K38/18 , A61K9/00 , C12N5/02 , A61P19/08
CPC分类号： A61K38/1875 , A61K31/727 , A61K31/737 , A61K35/28 , A61K2035/124 , A61L27/26 , A61L27/365 , A61L27/3834 , A61L27/3847 , A61L27/54 , A61L2300/236 , A61L2300/252 , A61L2300/414 , A61L2430/02 , B01D15/3823 , C07K14/51 , C08B37/0003 , C08B37/0075 , C12N5/0663 , C12N2501/155 , C12N2501/90
摘要： The invention relates to heparan sulphate GAGs obtained by affinity chromatography using the heparin-binding domain of BMP2. The GAGs were obtained from osteoblast extracellular matrix and from a commercially available heparan sulfate (Celsus HS).
摘要翻译：本发明涉及通过使用BMP2的肝素结合结构域的亲和层析获得的硫酸乙酰肝素GAG。 GAG由成骨细胞细胞外基质和市售的硫酸乙酰肝素（Celsus HS）获得。

4. 发明授权

US09498494B2 Glycosaminoglycans 有权
公开(公告)号：US09498494B2
公开(公告)日：2016-11-22
申请号：US13603569
申请日：2012-09-05
申请人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
发明人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC分类号： A61K31/727 , A61K38/18 , A61L27/54 , C08B37/00 , C08B37/10 , A61L27/20 , A61K9/00
CPC分类号： A61K31/727 , A61K9/0024 , A61K35/28 , A61K38/1875 , A61L27/20 , A61L27/54 , C08B37/0075
摘要： Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.

5. 发明申请

US20150071184A1 METHOD FOR A TRANSMITTER FOR A MULTI-CHANNEL COMMUNICATION SYSTEM FOR SENDING REAL-TIME DATA 有权
标题翻译：用于发送实时数据的多信道通信系统的发射机的方法
公开(公告)号：US20150071184A1
公开(公告)日：2015-03-12
申请号：US14110493
申请日：2012-04-05
申请人： Christian Dombrowski , James Gross
发明人： Christian Dombrowski , James Gross
IPC分类号： H04L5/00
CPC分类号： H04L5/0053 , H04B1/74 , H04L1/0009 , H04L1/04 , H04L1/0625 , H04L1/08 , H04L5/003
摘要： The invention relates to a method for a transmitter for a multi-channel communication system for sending real-time sensitive data D, wherein the communication system has n sub-channels, wherein n is greater than 1, wherein the sub-channels are spatially different and/or the sub-channels have different frequencies. The method comprises the steps of receiving information about the channel state of the n sub-channels, receiving information about the number of statistically independent sub-channels m, wherein m is less than or equal to n, and receiving dataD intended to be sent. When the method is performed, data D intended to be sent are divided into Ifragments and a plurality o of messages to be sent to at least one receiver are provided, wherein the number of messages o is less than or equal to the number of statistically independent sub-channels m, wherein each of the messages has at least one fragment, wherein one of the messages additionally has at least one part of a fragment, wherein at least one fragment in the plurality o of messages is contained at least r times in different messages as a fragment and/or at least as the part of the fragment, wherein r is greater than or equal to 1, and wherein r is determined on the basis of the number of statistically independent sub-channels m present and the size of the data to be sent. Then said plurality o of messages is sent, wherein each message is sent by means of a different channel of the o channels.
摘要翻译：本发明涉及一种用于发送实时敏感数据D的多信道通信系统的发射机的方法，其中通信系统具有n个子信道，其中n大于1，其中子信道在空间上不同和/或子通道具有不同的频率。该方法包括以下步骤：接收关于n个子信道的信道状态的信息，接收关于统计上独立的子信道m的数量的信息，其中m小于或等于n，并接收预期发送的数据D。当执行该方法时，要发送的数据D被划分成Ifragments，并且提供要发送给至少一个接收器的多个消息，其中消息的数量o小于或等于统计独立的数量子信道m，其中每个消息具有至少一个片段，其中所述消息中的一个附加地具有片段的至少一部分，其中所述多个消息中的至少一个片段至少包含r次的不同消息作为片段和/或至少作为片段的一部分，其中r大于或等于1，并且其中r基于当前存在的统计独立子信道的数量和所述片段的大小来确定要发送的数据然后发送所述多个消息，其中每个消息通过o个信道的不同信道发送。

6. 发明申请

US20130045249A1 Glycosaminoglycans 有权
标题翻译：糖胺聚糖
公开(公告)号：US20130045249A1
公开(公告)日：2013-02-21
申请号：US13603569
申请日：2012-09-05
申请人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
发明人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC分类号： A61K31/727 , A61P19/00 , A61K9/00 , C08B37/10 , A61K38/18
CPC分类号： A61K31/727 , A61K9/0024 , A61K35/28 , A61K38/1875 , A61L27/20 , A61L27/54 , C08B37/0075
摘要： Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.
摘要翻译：公开了硫酸肝素HS / BMP2，以及HS / BMP2在骨组织修复和再生中的应用。

7. 发明申请

US20110159071A1 Isolation and Identification of Glycosaminoglycans 审中-公开
标题翻译：糖胺聚糖的分离鉴定
公开(公告)号：US20110159071A1
公开(公告)日：2011-06-30
申请号：US13062297
申请日：2009-02-19
申请人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
发明人： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC分类号： A61F2/00 , A61K35/12 , G01N33/53 , C12N5/077 , C12N5/02 , A61P17/02 , A61P19/00 , A61P43/00 , A61K38/14 , C07K9/00 , C07H1/00
CPC分类号： A61K38/1875 , A61K31/727 , A61K31/737 , A61K35/28 , A61K2035/124 , A61L27/26 , A61L27/365 , A61L27/3834 , A61L27/3847 , A61L27/54 , A61L2300/236 , A61L2300/252 , A61L2300/414 , A61L2430/02 , B01D15/3823 , C07K14/51 , C08B37/0003 , C08B37/0075 , C12N5/0663 , C12N2501/155 , C12N2501/90
摘要： The isolation and identification of glycosaminoglycans capable of binding to proteins having a heparin-binding domain is disclosed, as well as the use of the glycosaminoglycans isolated in the growth and/or development of tissue.
摘要翻译：公开了能够结合具有肝素结合结构域的蛋白质的糖胺聚糖的分离和鉴定，以及在组织的生长和/或发育中分离的糖胺聚糖的用途。

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