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1. 发明申请

US20110073119A1 NEGATIVE PRESSURE ORAL APPARATUS 有权
标题翻译：负压口腔器具
公开(公告)号：US20110073119A1
公开(公告)日：2011-03-31
申请号：US12891398
申请日：2010-09-27
申请人： Chung-Chu CHEN , Ching SHANG , Marina SIROTA , Zhen YAO
发明人： Chung-Chu CHEN , Ching SHANG , Marina SIROTA , Zhen YAO
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61C17/04 , A61F5/56 , A61M1/0023 , A61M1/0066 , A61M16/0488 , A61M39/08
摘要： This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patentcy of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere. The negative pressure will also pull the soft palate into contact with the rear surface of the tongue to create a seal that prevents the air from entering the oral cavity through the nasal airway.
摘要翻译：本发明提供一种能够通过将迷你口腔界面施加负压口腔来缓解或治愈打鼾和阻塞性睡眠呼吸暂停的口腔装置和方法。迷你口腔界面在接口和嘴或牙齿之间产生牢固的连接，并防止接口脱落。口腔界面还提供上唇和下唇（或牙齿）之间的固定，并防止睡眠期间患者口腔的打开。负压将舌头拉向上腭，并将软腭向前拉。通过向前移动舌头和软腭，保持咽部附近上呼吸道的专利权，以防止睡眠呼吸紊乱。负压会将嘴唇向内拉，以闭合嘴巴，防止空气从大气进入口腔。负压也会使软腭与舌头的后表面接触，以产生防止空气通过鼻气道进入口腔的密封。

2. 发明授权

US07741505B2 Bisbiphenylacylphosphine oxide and preparation method therefore 有权
标题翻译：二苯基酰基氧化膦及其制备方法
公开(公告)号：US07741505B2
公开(公告)日：2010-06-22
申请号：US12141354
申请日：2008-06-18
申请人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
发明人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
IPC分类号： C07F9/02
CPC分类号： C07F9/657172
摘要： A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
摘要翻译：提供式（I）的双联苯酰基氧化膦及其制备方法。 -Ar-的配方是通过使用2-苯基苯酚制备10-氯-9,10-二氢-9-氧杂-10-磷杂菲（CDOP），然后酯化合成6-甲氧基 - （6H） - - 二苯并[c，e] [1,2]氧杂 - 磷杂（MDOP）。接下来，加入酰氯化合物进行Arbuzov反应以合成双联苯基酰基氧化膦。将CDOP水解成9,10-二氢-9-氧杂-10-磷杂蒽-10-氧化物（DOPO），然后DOPO与芳基醛反应形成仲醇。因此，通过使用仲醇在氧化下制备双联苯基酰基氧化膦。此外，在偶联反应中，DOPO通过使用路易斯酸作为催化剂与酰基氯化合物反应以制备双联苯基酰基氧化膦。

3. 发明申请

US20080287701A1 BISBIPHENYLACYLPHOSPHINE OXIDE AND PREPARATION METHOD THEREFORE 有权
标题翻译：二苯基乙基氧化膦及其制备方法
公开(公告)号：US20080287701A1
公开(公告)日：2008-11-20
申请号：US12141380
申请日：2008-06-18
申请人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
发明人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
IPC分类号： C07F9/6571
CPC分类号： C07F9/657172
摘要： A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
摘要翻译：提供式（I）的双联苯酰基氧化膦及其制备方法。 -Ar-的配方是通过使用2-苯基苯酚制备10-氯-9,10-二氢-9-氧杂-10-磷杂菲（CDOP），然后酯化合成6-甲氧基 - （6H） - 二苯并[c，e] [1,2]氧杂 - 磷杂（MDOP）。接下来，加入酰氯化合物进行Arbuzov反应以合成双联苯基酰基氧化膦。将CDOP水解成9,10-二氢-9-氧杂-10-磷杂蒽-10-氧化物（DOPO），然后DOPO与芳基醛反应形成仲醇。因此，通过使用仲醇在氧化下制备双联苯基酰基氧化膦。此外，在偶联反应中，DOPO通过使用路易斯酸作为催化剂与酰基氯化合物反应以制备双联苯基酰基氧化膦。

4. 发明授权

US09387117B2 Negative pressure oral apparatus 有权
标题翻译：负压口服器
公开(公告)号：US09387117B2
公开(公告)日：2016-07-12
申请号：US12891398
申请日：2010-09-27
申请人： Chung-Chu Chen , Ching Shang , Marina Sirota , Zhen Yao
发明人： Chung-Chu Chen , Ching Shang , Marina Sirota , Zhen Yao
IPC分类号： A61F5/56 , A61M16/04 , A61M1/00 , A61C17/06
CPC分类号： A61F5/566 , A61C17/04 , A61F5/56 , A61M1/0023 , A61M1/0066 , A61M16/0488 , A61M39/08
摘要： This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patency of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere. The negative pressure will also pull the soft palate into contact with the rear surface of the tongue to create a seal that prevents the air from entering the oral cavity through the nasal airway.
摘要翻译：本发明提供一种能够通过将迷你口腔界面施加负压口腔来缓解或治愈打鼾和阻塞性睡眠呼吸暂停的口腔装置和方法。迷你口腔界面在接口和嘴或牙齿之间产生牢固的连接，并防止接口脱落。口腔界面还提供上唇和下唇（或牙齿）之间的固定，并防止睡眠期间患者口腔的打开。负压将舌头拉向上腭，并将软腭向前拉。通过向前移动舌头和软腭，保持咽部附近上呼吸道的通畅，防止睡眠呼吸紊乱。负压会将嘴唇向内拉，以闭合嘴巴，防止空气从大气进入口腔。负压也会使软腭与舌头的后表面接触，以产生防止空气通过鼻气道进入口腔的密封。

5. 发明授权

US08040102B2 Solar-powered LED street light 有权
标题翻译：太阳能LED路灯
公开(公告)号：US08040102B2
公开(公告)日：2011-10-18
申请号：US12360168
申请日：2009-01-27
申请人： Ching-Shang Kao , Wei-Liang Lin
发明人： Ching-Shang Kao , Wei-Liang Lin
IPC分类号： H01M10/44 , H01M10/46
CPC分类号： F21S9/035 , F21S8/086 , F21W2131/103 , F21Y2115/10 , H05B37/0263 , Y02B20/72 , Y10S136/291 , Y10S362/80
摘要： A solar-powered LED street light that can immediately report its power data. The disclosed LED street light has a solar cell, a switch power supply unit, and a power cable data communicating unit. The mains power cable of the LED street light connects to the switch power supply unit for providing it with DC power. The solar cell has a solar board, a battery and a charge controller. The charge controller can also provide the LED street light with DC power. The charge controller has a power data digital output interface for connecting with the power cable data communicating unit, outputting the power data of the solar cell to the power cable data communicating unit. Through the mains power cable, the status of solar cell of each LED lamp is monitored.
摘要翻译：太阳能LED路灯，可以立即报告其功率数据。所公开的LED路灯具有太阳能电池，开关电源单元和电力电缆数据通信单元。 LED路灯的主电源线连接到开关电源单元，为其提供直流电源。太阳能电池具有太阳能板，电池和充电控制器。充电控制器还可以为LED路灯提供直流电源。充电控制器具有用于与电力电缆数据通信单元连接的电力数据数字输出接口，将太阳能电池的电力数据输出到电力电缆数据通信单元。通过主电源线，监视每个LED灯的太阳能电池的状态。

6. 发明申请

US20090303703A1 Solar-Powered LED Street Light 有权
标题翻译：太阳能LED路灯
公开(公告)号：US20090303703A1
公开(公告)日：2009-12-10
申请号：US12360168
申请日：2009-01-27
申请人： Ching-Shang Kao , Wei-Liang Lin
发明人： Ching-Shang Kao , Wei-Liang Lin
IPC分类号： F21L4/00
CPC分类号： F21S9/035 , F21S8/086 , F21W2131/103 , F21Y2115/10 , H05B37/0263 , Y02B20/72 , Y10S136/291 , Y10S362/80
摘要： A solar-powered LED street light that can immediately report its power data. The disclosed LED street light has a solar cell, a switch power supply unit, and a power cable data communicating unit. The mains power cable of the LED street light connects to the switch power supply unit for providing it with DC power. The solar cell has a solar board, a battery and a charge controller. The charge controller can also provide the LED street light with DC power. The charge controller has a power data digital output interface for connecting with the power cable data communicating unit, outputting the power data of the solar cell to the power cable data communicating unit. Through the mains power cable, the status of solar cell of each LED lamp is monitored.
摘要翻译：太阳能LED路灯，可以立即报告其功率数据。所公开的LED路灯具有太阳能电池，开关电源单元和电力电缆数据通信单元。 LED路灯的主电源线连接到开关电源单元，为其提供直流电源。太阳能电池具有太阳能板，电池和充电控制器。充电控制器还可以为LED路灯提供直流电源。充电控制器具有用于与电力电缆数据通信单元连接的电力数据数字输出接口，将太阳能电池的电力数据输出到电力电缆数据通信单元。通过主电源线，监视每个LED灯的太阳能电池的状态。

7. 发明授权

US07825274B2 Bisbiphenylacylphosphine oxide and preparation method therefore 有权
公开(公告)号：US07825274B2
公开(公告)日：2010-11-02
申请号：US12141380
申请日：2008-06-18
申请人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
发明人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
IPC分类号： C07F9/02
CPC分类号： C07F9/657172
摘要： A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.

8. 发明申请

US20080255381A1 BISBIPHENYLACYLPHOSPHINE OXIDE AND PREPARATION METHOD THEREFORE 有权
公开(公告)号：US20080255381A1
公开(公告)日：2008-10-16
申请号：US12141354
申请日：2008-06-18
申请人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
发明人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
IPC分类号： C07F9/40
CPC分类号： C07F9/657172
摘要： A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.

9. 发明申请

US20070173659A1 Bisbiphenylacylphosphine oxide and preparation method therefore 有权
标题翻译：二苯基酰基氧化膦及其制备方法
公开(公告)号：US20070173659A1
公开(公告)日：2007-07-26
申请号：US11337441
申请日：2006-01-24
申请人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
发明人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
IPC分类号： C07F9/02
CPC分类号： C07F9/657172
摘要： A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
摘要翻译：提供式（I）的双联苯酰基氧化膦及其制备方法。 -Ar-的配方是通过使用2-苯基苯酚制备10-氯-9,10-二氢-9-氧杂-10-磷杂菲（CDOP），然后酯化合成6-甲氧基 - （6H） - 二苯并[c，e] [1,2]氧杂 - 磷杂（MDOP）。接下来，加入酰氯化合物进行Arbuzov反应以合成双联苯基酰基氧化膦。将CDOP水解成9,10-二氢-9-氧杂-10-磷杂蒽-10-氧化物（DOPO），然后DOPO与芳基醛反应形成仲醇。因此，通过使用仲醇在氧化下制备双联苯基酰基氧化膦。此外，在偶联反应中，DOPO通过使用路易斯酸作为催化剂与酰基氯化合物反应以制备双联苯基酰基氧化膦。

10. 发明授权

US07465819B2 Bisbiphenylacylphosphine oxide and preparation method therefore 有权
标题翻译：二苯基酰基氧化膦及其制备方法
公开(公告)号：US07465819B2
公开(公告)日：2008-12-16
申请号：US11337441
申请日：2006-01-24
申请人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
发明人： Wen-Chiung Su , Chang-Chih Lin , Ching-Shang Sheng
IPC分类号： C07F9/02
CPC分类号： C07F9/657172
摘要： A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
摘要翻译：提供式（I）的双联苯酰基氧化膦及其制备方法。 -Ar-的配方是通过使用2-苯基苯酚制备10-氯-9,10-二氢-9-氧杂-10-磷杂菲（CDOP），然后酯化合成6-甲氧基 - （6H） - 二苯并[c，e] [1,2]氧杂 - 磷杂（MDOP）。接下来，加入酰氯化合物进行Arbuzov反应以合成双联苯基酰基氧化膦。将CDOP水解成9,10-二氢-9-氧杂-10-磷杂蒽-10-氧化物（DOPO），然后DOPO与芳基醛反应形成仲醇。因此，通过使用仲醇在氧化下制备双联苯基酰基氧化膦。此外，在偶联反应中，DOPO通过使用路易斯酸作为催化剂与酰基氯化合物反应以制备双联苯基酰基氧化膦。

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