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1. 发明授权

US09556860B2 Implantable infusion device having selective voltage boost circuit with charge pump circuit for generating control signals using first and second profiles 有权
标题翻译：具有带电荷泵电路的选择性升压电路的植入式输注装置，用于使用第一和第二轮廓产生控制信号
公开(公告)号：US09556860B2
公开(公告)日：2017-01-31
申请号：US13458147
申请日：2012-04-27
申请人： Charles Randall Rogers , Christopher Ambri
发明人： Charles Randall Rogers , Christopher Ambri
IPC分类号： A61M5/142 , F04B19/00 , H02M3/07 , H02M1/36
CPC分类号： F04B19/006 , A61M5/14276 , A61M5/1452 , A61M2205/18 , A61M2205/8206 , A61M2205/8212 , H02J1/14 , H02J7/345 , H02M1/36 , H02M3/07
摘要： An implantable infusion device includes a voltage boost circuit configured to selectively generate an output voltage from a first voltage provided by a battery. The voltage boost circuit includes a signal generation circuit configured to generate control signals and a charge pump circuit configured to generate the output voltage in response to the control signals. In response to a request for a predetermined voltage, the signal generation circuit generates the control signals using a first profile for a first period of time, and generates the control signals using a second profile for a second period of time subsequent to the first period. The charge pump circuit increases the output voltage to (i) an intermediate voltage less than the predetermined voltage in response to the first profile of the control signals, and (ii) the predetermined voltage in response to the second profile of the control signals.
摘要翻译：可植入输注装置包括升压电路，其被配置为从由电池提供的第一电压选择性地产生输出电压。升压电路包括被配置为产生控制信号的信号生成电路和被配置为响应于控制信号产生输出电压的电荷泵电路。响应于对预定电压的请求，信号产生电路使用第一时间段的第一配置文件产生控制信号，并且在第一时段之后的第二时间段内使用第二配置文件生成控制信号。电荷泵电路响应于控制信号的第一轮廓而将输出电压增加到（i）小于预定电压的中间电压，以及（ii）响应于控制信号的第二轮廓的预定电压。

2. 发明申请

US20130289539A1 Power Management System for a Piston-Based Implantable Infusion Pump 有权
标题翻译：基于活塞式植入式输液泵的电源管理系统
公开(公告)号：US20130289539A1
公开(公告)日：2013-10-31
申请号：US13458150
申请日：2012-04-27
申请人： Scott A. Sarkinen , Christopher Ambri , Charles Randall Rogers , Naveed Alam
发明人： Scott A. Sarkinen , Christopher Ambri , Charles Randall Rogers , Naveed Alam
IPC分类号： A61M5/142 , A61M5/145
CPC分类号： F04B19/006 , A61M5/14276 , A61M5/1452 , A61M2205/18 , A61M2205/8206 , A61M2205/8212 , H02J1/14 , H02J7/345 , H02M1/36 , H02M3/07
摘要： An implantable infusion device includes a pump, a charge storage unit, and a charging circuit configured to supply current to the charge storage unit from a battery in preparation for actuating the pump. The implantable infusion device also includes a pump actuator circuit configured to actuate the pump using energy from the charge storage unit, and a voltage boost circuit configured to provide a boosted battery voltage generated from the battery. The charging circuit is configured to supply current to the charge storage unit from the voltage boost circuit instead of directly from the battery in response to (i) a comparison of a voltage of the battery with a predetermined threshold and (ii) a comparison of a voltage of the charge storage unit with the voltage of the battery.
摘要翻译：可植入输注装置包括泵，电荷存储单元和充电电路，该充电电路被配置为从用于致动泵的准备中的电池向电荷存储单元提供电流。可植入输注装置还包括泵致动器电路，该泵致动器电路被配置为使用来自电荷存储单元的能量致动泵，以及升压电路，被配置为提供从电池产生的升压的电池电压。充电电路被配置为响应于（i）电池的电压与预定阈值的比较，而不是直接从电池的比较而从电压升压电路而不是直接从电池向电荷存储单元提供电流;以及（ii）电池存储单元的电压与电池的电压。

3. 发明申请

US20090082757A1 PRESSURE BASED REFILL STATUS MONITOR FOR IMPLANTABLE PUMPS 有权
标题翻译：基于压力的灌注状态监测器
公开(公告)号：US20090082757A1
公开(公告)日：2009-03-26
申请号：US12199536
申请日：2008-08-27
申请人： Charles Randall Rogers , Scott L. Kalpin , William J. Mitchell
发明人： Charles Randall Rogers , Scott L. Kalpin , William J. Mitchell
IPC分类号： A61M5/168
CPC分类号： A61M5/14276 , A61M5/16854 , A61M2205/3331 , A61M2205/3382 , A61M2205/3386 , A61M2209/045
摘要： The present invention includes systems and methods for detecting fluid flow into or out of a port chamber or a reservoir of an implantable medical device utilizing a pressure sensor. The system detects characteristic pressure profiles associated with fluid flowing into the medical device, out of the medical device, and also whether one or both of the port chamber or reservoir are substantially empty or substantially full. In addition, the present invention may generate a sensory cue to a clinician to indicate the fluid status.
摘要翻译：本发明包括用于检测流入或流出使用压力传感器的可植入医疗装置的端口室或储存器的流体的系统和方法。该系统检测与流入医疗装置的流体相关的特征压力分布，离开医疗装置，以及端口腔室或储存器中的一个或两个基本上是空的还是基本上满的。此外，本发明可以产生临床医生的感觉提示以指示流体状态。

4. 发明授权

US09555188B2 Implantable infusion device having voltage boost circuit and selection circuit to alternately connect battery with charging circuit 有权
标题翻译：具有升压电路和选择电路的植入式输液装置，可以将电池与充电电路交替连接
公开(公告)号：US09555188B2
公开(公告)日：2017-01-31
申请号：US13458150
申请日：2012-04-27
申请人： Scott A. Sarkinen , Christopher Ambri , Charles Randall Rogers , Naveed Alam
发明人： Scott A. Sarkinen , Christopher Ambri , Charles Randall Rogers , Naveed Alam
IPC分类号： A61M5/142 , H02J1/14 , H02J7/34 , A61M5/145
CPC分类号： F04B19/006 , A61M5/14276 , A61M5/1452 , A61M2205/18 , A61M2205/8206 , A61M2205/8212 , H02J1/14 , H02J7/345 , H02M1/36 , H02M3/07
摘要： An implantable infusion device includes a pump, a charge storage unit, and a charging circuit configured to supply current to the charge storage unit from a battery in preparation for actuating the pump. The implantable infusion device also includes a pump actuator circuit configured to actuate the pump using energy from the charge storage unit, and a voltage boost circuit configured to provide a boosted battery voltage generated from the battery. The charging circuit is configured to supply current to the charge storage unit from the voltage boost circuit instead of directly from the battery in response to (i) a comparison of a voltage of the battery with a predetermined threshold and (ii) a comparison of a voltage of the charge storage unit with the voltage of the battery.
摘要翻译：可植入输注装置包括泵，电荷存储单元和充电电路，该充电电路被配置为从用于致动泵的准备中的电池向电荷存储单元提供电流。可植入输注装置还包括泵致动器电路，该泵致动器电路被配置为使用来自电荷存储单元的能量致动泵，以及升压电路，被配置为提供从电池产生的升压的电池电压。充电电路被配置为响应于（i）电池的电压与预定阈值的比较，而不是直接从电池的比较而从电压升压电路而不是直接从电池向电荷存储单元提供电流;以及（ii）电池存储单元的电压与电池的电压。

5. 发明申请

US20130289538A1 Charge Pump Sequencing for Minimizing In-Rush Current 有权
标题翻译：电荷泵排序最小化冲击电流
公开(公告)号：US20130289538A1
公开(公告)日：2013-10-31
申请号：US13458147
申请日：2012-04-27
申请人： Charles Randall Rogers , Christopher Ambri
发明人： Charles Randall Rogers , Christopher Ambri
IPC分类号： A61M5/142
CPC分类号： F04B19/006 , A61M5/14276 , A61M5/1452 , A61M2205/18 , A61M2205/8206 , A61M2205/8212 , H02J1/14 , H02J7/345 , H02M1/36 , H02M3/07
摘要： An implantable infusion device includes a voltage boost circuit configured to selectively generate an output voltage from a first voltage provided by a battery. The voltage boost circuit includes a signal generation circuit configured to generate control signals and a charge pump circuit configured to generate the output voltage in response to the control signals. In response to a request for a predetermined voltage, the signal generation circuit generates the control signals using a first profile for a first period of time, and generates the control signals using a second profile for a second period of time subsequent to the first period. The charge pump circuit increases the output voltage to (i) an intermediate voltage less than the predetermined voltage in response to the first profile of the control signals, and (ii) the predetermined voltage in response to the second profile of the control signals.
摘要翻译：可植入输注装置包括升压电路，其被配置为从由电池提供的第一电压选择性地产生输出电压。升压电路包括被配置为产生控制信号的信号生成电路和被配置为响应于控制信号产生输出电压的电荷泵电路。响应于对预定电压的请求，信号产生电路使用第一时间段的第一配置文件产生控制信号，并且在第一时段之后的第二时间段内使用第二配置文件生成控制信号。电荷泵电路响应于控制信号的第一轮廓而将输出电压增加到（i）小于预定电压的中间电压，以及（ii）响应于控制信号的第二轮廓的预定电压。

6. 发明授权

US08535280B2 Pressure based refill status monitor for implantable pumps 有权
标题翻译：用于植入式泵的基于压力的补充状态监测器
公开(公告)号：US08535280B2
公开(公告)日：2013-09-17
申请号：US12199536
申请日：2008-08-27
申请人： Charles Randall Rogers , Scott L. Kalpin , William J. Mitchell
发明人： Charles Randall Rogers , Scott L. Kalpin , William J. Mitchell
IPC分类号： A61M37/00
CPC分类号： A61M5/14276 , A61M5/16854 , A61M2205/3331 , A61M2205/3382 , A61M2205/3386 , A61M2209/045
摘要： The present invention includes systems and methods for detecting fluid flow into or out of a port chamber or a reservoir of an implantable medical device utilizing a pressure sensor. The system detects characteristic pressure profiles associated with fluid flowing into the medical device, out of the medical device, and also whether one or both of the port chamber or reservoir are substantially empty or substantially full. In addition, the present invention may generate a sensory cue to a clinician to indicate the fluid status.
摘要翻译：本发明包括用于检测流入或流出使用压力传感器的可植入医疗装置的端口室或储存器的流体的系统和方法。该系统检测与流入医疗装置的流体相关的特征压力分布，离开医疗装置，以及端口腔室或储存器中的一个或两个基本上是空的还是基本上满的。此外，本发明可以产生临床医生的感觉提示以指示流体状态。

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