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1. 发明申请

US20120116434A1 Scissors Assembly 有权
标题翻译：剪刀装配
公开(公告)号：US20120116434A1
公开(公告)日：2012-05-10
申请号：US13299467
申请日：2011-11-18
申请人： Charles R. Slater
发明人： Charles R. Slater
IPC分类号： A61B17/3201
CPC分类号： A61B17/320016 , A61B17/3201
摘要： An endoscopic scissor instrument includes an elongate hollow member, an actuator that moves axially through the hollow member, and first and second scissor blades with respective cutting surfaces. At least one of the scissor blades is rotatably coupled to the hollow member adjacent its distal end. At least one of the scissor blades includes a base supporting a resilient leaf-spring portion that includes a respective cutting edge. The resilient leaf-spring portion extends from the base in a cantilevered arrangement and generates a spring force acting on the respective cutting edge such that in a loaded state there is an automatic preload force imparted between the cutting edges of the scissor blades to maintain a consistent and continuous mating force between the two opposed sharpened cutting edges preferably over the complete range of rotational movement of the scissor blades.
摘要翻译：内窥镜剪刀器具包括细长的中空构件，轴向移动穿过中空构件的致动器以及具有相应切割表面的第一和第二剪刀片。至少一个剪刀叶片可靠地连接到中空构件的远端。至少一个剪刀片包括支撑包括相应切割刃的弹性片弹簧部分的底座。弹性片弹簧部分从基部以悬臂布置的方式延伸并产生作用在相应切削刃上的弹簧力，使得在加载状态下，在剪刀叶片的切割刃之间施加自动预加载力以保持一致并且两个相对的锋利切削刃之间的连续配合力优选地在剪刀叶片的完全旋转运动范围内。

2. 发明授权

US07985200B2 Apparatus for delivering an intravascular drug 有权
标题翻译：用于输送血管内药物的装置
公开(公告)号：US07985200B2
公开(公告)日：2011-07-26
申请号：US11381372
申请日：2006-05-03
申请人： Banning G. Lary , Leonard Pinchuk , Saul Gottlieb , Charles R. Slater
发明人： Banning G. Lary , Leonard Pinchuk , Saul Gottlieb , Charles R. Slater
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61B17/320725 , A61B2017/22038 , A61B2017/22067 , A61B2017/22082 , A61M25/1011 , A61M2025/0004 , A61M2025/0175 , A61M2025/105 , A61M2025/1052 , A61M2025/1068
摘要： A preferred apparatus for delivering an intravascular drug such as a sclerosing agent (or a microfoam sclerosing agent) to a varicose vein includes a catheter having three concentric tubes. The innermost tube has a guide wire lumen and an inflation lumen. The distal end of the innermost tube has an integral inflatable occlusion balloon in fluid communication with the inflation lumen. The intermediate tube has a lumen through which the innermost tube extends. The distal end of the intermediate tube has a self-expanding balloon with a plurality of fluid pores in fluid communication with the intermediate tube lumen. The outer tube has a lumen through which the intermediate tube extends. Sclerosing agent is dispensed through the intermediate tube to pores located at the distal end of the intermediate tube or in the self-expanding balloon. Veins are sclerosed as the self-expanding balloon is pulled through and ultimately out of the vein.
摘要翻译：用于将诸如硬化剂（或微泡硬化剂）的血管内药物递送到静脉曲张的优选装置包括具有三个同心管的导管。最内管具有导丝管腔和充气腔。最内管的远端具有与膨胀腔流体连通的整体充气闭塞球囊。中间管具有内管，最内管延伸通过该内腔。中间管的远端具有自膨胀气囊，其具有与中间管腔流体连通的多个流体孔。外管具有中空管延伸通过的内腔。硬化剂通过中间管分配到位于中间管的远端或自膨胀气囊中的孔。静脉由于自膨胀的气囊被拉过并最终脱离静脉，因此是硬化的。

3. 发明申请

US20100298638A1 Endoscopic Instrument with Bi-Laterally Widened Cam-Slot at End Effector 有权
标题翻译：内窥镜仪器在双向扩张凸轮槽端面效应器
公开(公告)号：US20100298638A1
公开(公告)日：2010-11-25
申请号：US12471041
申请日：2009-05-22
申请人： Charles R. Slater
发明人： Charles R. Slater
IPC分类号： A61B1/018
CPC分类号： A61B17/295 , A61B17/3201 , A61B2017/2825 , A61B2017/2936 , A61B2017/320064
摘要： An endoscopic instrument includes a tubular member having a proximal end and a distal end, a clevis at the distal end of the tubular member, and an end effector assembly mounted on the clevis. A control member extends through the tubular member and includes a cam-pin coupled to the distal end thereof. The end effectors are controlled with a cam-pin and cam-slot arrangement, with the end effectors including the cam-slot and such cam-slot having a proximal end slot bilaterally widened to permit the cam-pin additional movement therein. When the cam-pin is retracted to move the end effectors into a closed positions and then further retracted into the bilaterally widened area, the end effectors can rotate together in the same direction to facilitate movement through a rigid bend in an endoscope.
摘要翻译：内窥镜器具包括具有近端和远端的管状构件，在管状构件的远端处的U形夹以及安装在U形夹上的端部执行器组件。控制构件延伸穿过管状构件并且包括联接到其远端的凸轮销。末端执行器用凸轮销和凸轮槽布置来控制，其中末端执行器包括凸轮槽，并且这种凸轮槽具有双向加宽的近端狭槽，以允许凸轮销在其中附加运动。当凸轮销缩回以将末端执行器移动到关闭位置并且然后进一步缩回到双边加宽区域中时，末端执行器可以沿相同方向一起旋转，以便于通过内窥镜中的刚性弯曲而移动。

4. 发明授权

US07780721B2 Stent and method for manufacturing the stent 有权
标题翻译：用于制造支架的支架和方法
公开(公告)号：US07780721B2
公开(公告)日：2010-08-24
申请号：US11216362
申请日：2005-08-31
申请人： Thomas O. Bales , Charles R. Slater , Scott L. Jahrmarkt
发明人： Thomas O. Bales , Charles R. Slater , Scott L. Jahrmarkt
IPC分类号： A61F2/06
CPC分类号： A61F2/88 , A61F2/844 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2002/0864 , A61F2002/91533 , A61F2002/91541 , A61F2002/91558 , A61F2002/91583 , A61F2002/9665 , A61F2250/0098
摘要： A stent includes a stent body having a circumference and struts disposed helically about the circumference. Each of the struts has a strut length and a ratio of a number of the struts around the circumference to the strut length is greater than 800 per inch, in particular, over 1000 per inch. A method for manufacturing a helical stent includes the steps of providing a stent body with struts disposed about the circumference thereof in turns and with bridges connecting the struts in adjacent turns. The stent body is expanded and, thereafter, some of the bridges, in particular, sacrificial bridges, are removed.
摘要翻译：支架包括具有围绕圆周螺旋设置的圆周和支柱的支架主体。每个支柱具有支柱长度，并且围绕圆周的支柱的数量与支柱长度的比率大于每英寸800个，特别是每英寸超过1000个。一种用于制造螺旋支架的方法包括以下步骤：提供支架主体，所述支架本体具有围绕其圆周设置的支柱，并且在相邻匝中连接支柱。支架主体被扩张，此后，除去一些桥，特别是牺牲桥。

5. 发明授权

US07727246B2 Methods for endoluminal treatment 有权
标题翻译：腔内治疗方法
公开(公告)号：US07727246B2
公开(公告)日：2010-06-01
申请号：US10010244
申请日：2001-12-06
申请人： Robert Sixto, Jr. , Michael Sean McBrayer , Juergen A. Kortenbach , Charles R. Slater , Kevin W. Smith
发明人： Robert Sixto, Jr. , Michael Sean McBrayer , Juergen A. Kortenbach , Charles R. Slater , Kevin W. Smith
IPC分类号： A61B17/08
CPC分类号： A61B17/122 , A61B1/00073 , A61B1/00087 , A61B1/0014 , A61B1/018 , A61B10/06 , A61B17/00234 , A61B17/0218 , A61B17/1227 , A61B17/1285 , A61B18/1445 , A61B90/50 , A61B2017/00292 , A61B2017/00296 , A61B2017/00464 , A61B2017/2936 , A61B2017/320064 , A61B2018/00577 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2090/306 , A61B2090/3614
摘要： Methods of the invention include delivering a grasper, a clip applier, and an endoscope transorally to the site of fundoplication; grasping the fundus with the grasper (or similar device, e.g. corkscrew) and pulling it into the jaws of the clip applier; closing the jaws of the clip applier over the fundus and applying a clip to the fundus.
摘要翻译：本发明的方法包括将抓持器，夹具施加器和内窥镜经皮递送至基层应用部位; 用抓紧器（或类似的装置，例如开瓶器）抓住眼底并将其拉入夹具的钳口中; 将夹子的钳口夹在眼底上，并将夹子应用于眼底。

6. 发明授权

US07063697B2 Bipolar endoscopic surgical scissor blades and instrument incorporating the same 失效
公开(公告)号：US07063697B2
公开(公告)日：2006-06-20
申请号：US10626599
申请日：2003-07-25
申请人： Charles R. Slater
发明人： Charles R. Slater
IPC分类号： A61B18/18
CPC分类号： A61B18/14 , A61B18/1445 , A61B18/1815 , A61B2018/00083 , A61B2018/00107 , A61B2018/00178 , A61B2018/126 , A61B2018/1412 , A61B2018/146 , A61B2018/1861
摘要： Endoscopic bipolar scissor blades are formed in a laminate assembly of an electrically conductive electrode, an electrically insulating material, and a metal shearing surface which is electrically insulated and physically spaced from the electrode by the insulating material which is disposed therebetween. In one embodiment, the electrode is a metal blade, while the insulating material is a ceramic which is fixed to the metal blade, and the metal shearing surface which also provides the cutting edge is of a metal material which is fixed to the ceramic. In a second embodiment, the insulating material is a molded ceramic blade, with the electrode and the metal shearing surface layer metalized or otherwise fixed to the ceramic blade. In a third embodiment, the electrode is metalized on a thin layer insulating material which is fixed onto a metallic blade. In a fourth embodiment, metallic shearing and electrode layers are laminated to opposite sides of a fiberglass material. In all embodiments, the metal cutting edges and surfaces are insulated from the electrodes, and no short circuit can form between the electrodes even though the cutting edges and shearing surfaces are metal.

7. 发明授权

US06796936B2 Implantable radiation therapy device having controllable radiation emission 失效
标题翻译：具有可控辐射发射的可植入放射治疗装置
公开(公告)号：US06796936B2
公开(公告)日：2004-09-28
申请号：US10281777
申请日：2002-10-28
申请人： Charles R. Slater , Scott L. Jahrmarkt , Scott T. Smith , Kevin W. Smith
发明人： Charles R. Slater , Scott L. Jahrmarkt , Scott T. Smith , Kevin W. Smith
IPC分类号： A61M3612
CPC分类号： A61N5/1027 , A61N2005/1005 , A61N2005/1024
摘要： An implantable radiation therapy device includes a biocompatible radiotranslucent outer capsule containing a radiation shielding element and a radioactive isotope at least partially shielded by the shielding element. When the device is at or below body temperature, radiation is prevented or limited from being transmitted through the outer capsule by the shielding element. When non-ambient energy is applied to the device, the shielding element and radioactive isotope are reconfigured such that an increased level of radiation is transmitted through the outer capsule and emitted by the device.
摘要翻译：可植入放射治疗装置包括生物相容的无辐射透明外胶囊，其包含至少部分被屏蔽元件屏蔽的辐射屏蔽元件和放射性同位素。当装置处于或低于体温时，防止或限制辐射通过屏蔽元件透过外胶囊。当非环境能量被施加到设备时，屏蔽元件和放射性同位素被重新配置，使得增加的辐射水平通过外部胶囊传输并被设备发射。

8. 发明授权

US06264617B1 Radial jaw biopsy forceps 失效
标题翻译：径向钳活检钳
公开(公告)号：US06264617B1
公开(公告)日：2001-07-24
申请号：US09414366
申请日：1999-10-12
申请人： Thomas O. Bales , Charles R. Slater , Kevin W. Smith
发明人： Thomas O. Bales , Charles R. Slater , Kevin W. Smith
IPC分类号： A61B1000
CPC分类号： A61B10/06 , A61B10/02 , A61B17/30 , A61B2010/0225 , A61B2017/00398 , A61B2017/2926 , A61B2017/2931 , A61B2017/2939 , A61B2018/1253 , A61B2018/1412 , A61B2018/1415 , A61B2018/1455 , A61B2018/146 , A61B2018/1861 , A61B2090/064 , A61M2025/0098
摘要： A biological forceps device for the taking of tissue samples from a body, comprising a flexible main coil attached at its distal end to a pair of homologous cast jaws. The jaws have radially arranged teeth on their distalmost end. The jaws are opened and closed by attachment to a pair of pull wires which extend through the main coil, into a handle at its proximal end. the handle has a spool which slides about a central shaft attached to the main coil. The spool is attached to the pull wires, so that movement of the spool with respect to the central shaft, effectuates a force on the proximal ends of the levered jaws, to open and close them, appropriately.
摘要翻译：一种用于从身体采集组织样本的生物镊子装置，包括在其远端处附接到一对同源颚爪的柔性主线圈。钳口在其最远端具有径向排列的齿。夹爪通过连接到延伸穿过主线圈的一对拉线打开和关闭，在其近端处于手柄中。手柄具有绕附接到主线圈的中心轴滑动的线轴。线轴被连接到拉线，使得线轴相对于中心轴的运动在适当地对杠杆钳口的近端施加力以打开和闭合它们。

9. 发明授权

US06264599B1 Radioactive therapeutic seeds having fixation structure 失效
标题翻译：具有固定结构的放射性治疗种子
公开(公告)号：US06264599B1
公开(公告)日：2001-07-24
申请号：US09371194
申请日：1999-08-10
申请人： Charles R. Slater , Kevin W. Smith , Scott L. Jahrmarkt , Scott T. Smith
发明人： Charles R. Slater , Kevin W. Smith , Scott L. Jahrmarkt , Scott T. Smith
IPC分类号： A61N500
CPC分类号： A61N5/1027 , A61N2005/1023 , A61N2005/1024
摘要： Radioactive therapeutic seeds include a substantially radiotransparent cylindrical capsule provided with a radioactive isotope, a radiopaque marker, and an engagement structure adapted to engage tissue surrounding the seeds at the implant site. The engagement structure is also preferably adapted to releasably engage the inside of a delivery needle prior to implantation. The engagement structure is preferably adapted to prevent axial longitudinal movement and axial rotation of a seed about its longitudinal axis when the seed is implanted. According to a preferred embodiment of the invention, the engagement structure includes three spring elements which are biased away from the seed capsule and which provide positive fixation in the tissue, and also frictionally engage the inside of the needle.
摘要翻译：放射性治疗种子包括设置有放射性同位素，不透射线标记物和适于在植入部位接合种子周围的组织的接合结构的基本上无辐射透明的圆柱形胶囊。接合结构还优选地适于在植入之前可释放地接合输送针的内部。接合结构优选地适于在种子植入时防止种子围绕其纵向轴线的轴向纵向移动和轴向旋转。根据本发明的优选实施例，接合结构包括偏离种子囊的三个弹簧元件，并且在组织中提供正的固定，并且还摩擦地接合针的内部。

10. 发明授权

US06258064B1 Helically advanceable endoscopic needle device 有权
标题翻译：螺旋可推进内窥镜针装置
公开(公告)号：US06258064B1
公开(公告)日：2001-07-10
申请号：US09411856
申请日：1999-10-04
申请人： Kevin W. Smith , Juergen A. Kortenbach , Charles R. Slater
发明人： Kevin W. Smith , Juergen A. Kortenbach , Charles R. Slater
IPC分类号： A61M5178
CPC分类号： A61B17/3478 , A61B2017/00367 , A61B2090/034
摘要： An endoscopic needle device includes an outer sheath, an elongate shaft extending through the sheath, a needle rigidly attached to the distal end of the shaft, and a handle assembly having a housing coupled to the proximal end of the sheath and having a syringe port in fluid communication with the sheath and a knob rotatably coupled to the housing. Rotation of the knob relative to the housing causes rotation of the shaft relative to the sheath. The needle and the distal end of the sheath are mated by a threaded connection. As such, rotation of the knob relative to the housing causes precise longitudinal movement and extension of the needle relative to the distal end of the sheath. A set of intermeshing gears are provided between the knob and shaft which function to permit at most one rotation of the knob to cause complete extension and/or retraction of the needle. Furthermore, assemblies are provided with permit the shaft to accommodate movement of the needle relative to the sheath. Moreover, the position of the knob relative to the housing provides an indication of the extension of the needle. As such, the injection needle device of the invention permits controllable and calibrated rotation of the needle to within a few degrees, such that the needle device can be easily, reliably, and precisely operated to advance the needle.
摘要翻译：内窥镜针装置包括外护套，延伸穿过护套的细长轴，刚性地附接到轴的远端的针和手柄组件，其具有联接到护套的近端的壳体，并且具有注射器端口与护套的流体连通和可旋转地联接到壳体的旋钮。旋钮相对于壳体的旋转导致轴相对于护套的旋转。针和鞘的远端通过螺纹连接配合。因此，旋钮相对于壳体的旋转导致针相对于护套的远端的精确的纵向移动和延伸。一组相互啮合的齿轮设置在旋钮和轴之间，其功能是允许旋钮的至多一个旋转引起针的完全伸展和/或缩回。此外，组件被设置有允许轴以适应针相对于护套的运动。此外，旋钮相对于壳体的位置提供针的延伸的指示。因此，本发明的注射针装置允许可控和校准的针旋转到几度，使得针装置可以容易地，可靠地和精确地操作以推进针。

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