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    • 4. 发明授权
    • Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe
    • 使用光纤探针定量测量组织内荧光和磷光药物的方法
    • US06377842B1
    • 2002-04-23
    • US09379001
    • 1999-08-23
    • Brian William PogueGregory Charles Burke
    • Brian William PogueGregory Charles Burke
    • A61B500
    • A61B5/0059A61B5/7242A61N5/0601A61N5/062
    • A fiber optic based probe has been designed to sample the fluorescence or phosphorescence signal from animal or human tissues, such that the light intensity is not multiply scattered. This type of measurement allows a linear detection of the concentration of the luminescent compound non-invasively from the tissue. The basic principle of the fiber probe is to use fiber optics which are smaller in diameter that the average scattering length of the tissue. In order to increase the detected signal to a stronger level, multiple fibers are used by spacing them out on the surface of the tissue so that each fiber samples an isolated section of tissue. Each fiber delivers the excitation light to the tissue, and receives the emission light from the tissue. All fibers are coupled into the same detector to integrate the overall signal. Sampling of the scattered excitation signal intensity is also done to correct for changes in the scattering coefficient between tissues. This fiber bundle can be used to quantify the concentration of fluorescence or phosphorescent chemicals in vivo non-invasively. One application of this device is as a dosimetry tool, to monitor photosensitizer drug concentration within tissue for photodynamic therapy.
    • 已经设计了一种基于光纤的探针来对动物或人体组织的荧光或磷光信号进行采样,使得光强度不会被分散。 这种类型的测量允许从组织非侵入地线性检测发光化合物的浓度。 纤维探针的基本原理是使用直径较小的纤维,即组织的平均散射长度。 为了将检测到的信号增加到更强的水平,通过在组织的表面上间隔多个纤维来使用多个纤维,使得每个纤维对组织的隔离部分进行采样。 每个纤维将激发光传递到组织,并接收来自组织的发射光。 所有光纤耦合到相同的检测器中以整合信号。 散射激发信号强度的采样也用于校正组织之间散射系数的变化。 该纤维束可用于非侵入性地定量体内荧光或磷光化学品的浓度。 该装置的一个应用是作为剂量测定工具,用于监测光动力疗法组织内的光敏剂药物浓度。
    • 6. 发明申请
    • Method and System for Creating a Record for One or More Computer Security Incidents
    • 为一个或多个计算机安全事件创建记录的方法和系统
    • US20080016569A1
    • 2008-01-17
    • US11777489
    • 2007-07-13
    • John HammerRixin GeCharles BurkeCharles Hubbard
    • John HammerRixin GeCharles BurkeCharles Hubbard
    • G08B23/00
    • G06F21/554
    • A security management system can log, investigate, respond, and track computer security incidents that can occur in a networked computer system. In other words, the security management system can produce a security record of information related to the tracking of suspicious computer activity or actual computer security threats, such as denial of service attacks or other similar compromises to computers or computer networks. The security record can include, but is not limited to, date and times of computer security incidents, a name for a particular security incident, a security management system user, and a potential source of the computer security incident. The security record can be designed as a running log that saves or records all activity of a computer incident source as well as the activity of the security team responding to the computer incident source. To produce the security record, all data that relates to a computer incident and all data that relates to a computer incident response can be sent to a separate protected database, where data is protected by digital signature algorithms (DSAs).
    • 安全管理系统可以记录,调查,响应和跟踪网络计算机系统中可能发生的计算机安全事件。 换句话说,安全管理系统可以产生与跟踪可疑计算机活动或实际的计算机安全威胁有关的信息的安全记录,例如拒绝服务攻击或其他类似的损害计算机或计算机网络。 安全记录可以包括但不限于计算机安全事件的日期和时间,特定安全事件的名称,安全管理系统用户以及计算机安全事件的潜在来源。 安全记录可以设计为运行日志,可以保存或记录计算机事件源的所有活动以及响应计算机事件源的安全团队的活动。 为了产生安全记录,与计算机事件相关的所有数据和与计算机事件响应相关的所有数据都可以发送到单独的受保护的数据库,数据由数字签名算法(DSA)保护。
    • 9. 发明授权
    • Full force web severer
    • 全力网更严格
    • US06658972B1
    • 2003-12-09
    • US09339725
    • 1999-06-24
    • David Charles Burke
    • David Charles Burke
    • B26D512
    • B26F3/02B26D1/065B26D5/12Y10T83/04Y10T83/8858
    • A first given pressure is provided to a first side of an air pressure cylinder that in turn drives a cutting member under the influence of the first given pressure. A second given pressure is provided to a second side of the air pressure cylinder that is greater than the first given pressure during a non-cutting state of the air cylinder. The cutting member remains stationary as long as the second given pressure is greater than the first given pressure. To transition to a cutting state, the second given pressure is rapidly reduced to a value below the first given pressure value during a cutting state of the air pressure cylinder for moving the cutting member to cut a web.
    • 第一给定压力被提供给空气压力缸的第一侧,气压缸又在第一给定压力的影响下驱动切割构件。 在气缸的非切削状态期间,第二给定压力被提供给空气压力缸的第二侧,其大于第一给定压力。 只要第二给定压力大于第一给定压力,切割构件保持静止。 为了转变到切割状态,在用于移动切割构件以切割幅材的气压缸的切割状态期间,将第二给定压力快速降低到低于第一给定压力值的值。