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1. 发明申请

US20050150769A1 Method of separating biocomponents contained in a liquid, a separating system and a separating unit 审中-公开
标题翻译：分离液体，分离系统和分离单元中包含的生物组分的方法
公开(公告)号：US20050150769A1
公开(公告)日：2005-07-14
申请号：US11004974
申请日：2004-12-07
申请人： Henrik Schmidt , Steffen Pryds , Carsten Faltum , Stephen Fey , Peter Larsen , Adam Rubin
发明人： Henrik Schmidt , Steffen Pryds , Carsten Faltum , Stephen Fey , Peter Larsen , Adam Rubin
IPC分类号： A61M1/00 , A61M1/02 , C07K1/28 , C07K14/195 , C07K14/415 , C07K14/47 , G01N27/447 , G01N33/559
CPC分类号： G01N27/44747 , G01N27/44773 , G01N27/44795
摘要： The invention relates to a method of separating at least two biocomponents contained in a liquid including having different pI values. The method comprising the steps of: i. providing a first separating path with at least one separating layer comprising one or more pH active components with pH active groups, ii. applying the liquid with the biocomponents to the separating coating, iii: applying a voltage over the separating path, iv. allowing at least some of the biocomponents to travel towards one of the electrodes to one or more collection stations, v. collecting the once separated biocomponents from at least one collection station. The invention also relates to a separating system for use in the method. The separation system comprises a set of separating paths, the separating system comprising 2 or more separating paths that differ from each other with respect to the pH value of the separating coating.
摘要翻译：本发明涉及一种分离包含在液体中的至少两种生物组分的方法，包括具有不同pI值。该方法包括以下步骤：i。提供具有至少一个包含一个或多个具有pH活性基团的pH活性组分的分离层的第一分离路径，ii。将液体与生物组分一起施加到分离涂层，iii：在分离路径上施加电压，iv。允许至少一些生物组分行进到一个或多个收集站的电极之一，v。从至少一个收集站收集一次分离的生物组分。本发明还涉及一种用于该方法的分离系统。分离系统包括一组分离路径，分离系统包含相对于分离涂层的pH值彼此不同的2个或更多个分离路径。

2. 发明申请

US20060096906A1 Microfluid biomolecule separation system 审中-公开
标题翻译：微流体生物分子分离系统
公开(公告)号：US20060096906A1
公开(公告)日：2006-05-11
申请号：US10531076
申请日：2003-10-13
申请人： Adam Rubin , Carsten Faltum
发明人： Adam Rubin , Carsten Faltum
IPC分类号： F02M37/22
CPC分类号： G01N27/44795 , G01N27/44773
摘要： The invention relates to a micro fluid biomolecule separation system comprising a primary separating path and one or more secondary process paths. The primary separating path being in the form of a separating coating carried on a substrate, wherein the separating coating comprises one or more separating layers, and at least one separating layer consists of or comprises one or more pH active components. The fluid biomolecule separation system comprises means for applying a voltage over the primary separating path. The secondary process paths(s) comprises one or more inlets in liquid communication with the primary separating path. The one or more inlets is placed along or extends along the primary separating path, whereby biomolecules separated along the primary path is capable of being introduced into the secondary process path(s) for being processed further.
摘要翻译：本发明涉及一种微流体生物分子分离系统，其包括主分离路径和一个或多个次要过程路径。主分离路径为载体在基底上的分离涂层形式，其中分离涂层包含一个或多个分离层，至少一个分离层由一种或多种pH活性组分组成或包含一种或多种pH活性组分。流体生物分子分离系统包括用于在主分离路径上施加电压的装置。二次加工路径包括与主分离路径液体连通的一个或多个入口。一个或多个入口沿着主分隔路径放置或沿主分隔路径延伸，由此沿着主路径分离的生物分子能够被引入二次过程路径中以进一步处理。

3. 发明申请

US20050103097A1 Sensor 审中-公开
标题翻译：传感器
公开(公告)号：US20050103097A1
公开(公告)日：2005-05-19
申请号：US10501911
申请日：2003-01-24
申请人： Carsten Faltum , Jacob Thaysen
发明人： Carsten Faltum , Jacob Thaysen
IPC分类号： B81B3/00 , B81B7/00 , B81B7/04 , G01N27/00 , G01N33/00 , G01N31/00
CPC分类号： B81B7/0006 , B81B7/04 , B81B2201/0214 , B81B2203/0109 , B82Y30/00 , G01N29/036 , G01N2291/0256
摘要： The invention relates to a sensor for detecting a substance in a liquid. The sensor comprises a pillar shaped primary substrate and a sensor unit, e.g. a cantilever connected to the primary substrate. The sensor comprises detecting means e.g. in the form of a piezoresistive element, a strain gauge, a Si or C nanotube, a capacitor or a piezoresistor, for detecting a change of stress or mass generated on a surface area of the sensor unit, and an electric communication line for applying a voltage over said detection means, wherein at least one of the wires is integrated in the pillar shaped primary substrate. The sensor in the form of a cantilever may e.g. have a two-dimensional shape selected from the group consisting of square, rectangular, triangular, pentagonal, hexagonal, leaf shaped, circular and oval periphery. The primary substrate may be connected to a secondary substrate such as an electronic chip comprising contact pads corresponding with wire exits from the primary substrate.
摘要翻译：本发明涉及一种用于检测液体中物质的传感器。该传感器包括柱形初级衬底和传感器单元，例如。连接到主基板的悬臂。传感器包括检测装置。以压敏元件，应变计，Si或C纳米管，电容器或压电电阻的形式，用于检测在传感器单元的表面区域上产生的应力或质量的变化，以及用于施加电压超过所述检测装置，其中至少一根电线集成在柱形初级衬底中。悬臂形式的传感器可以例如具有从由正方形，矩形，三角形，五边形，六边形，叶状，圆形和椭圆形周边组成的组中选择的二维形状。初级衬底可以连接到次级衬底，例如包括对应于从初级衬底的导线出口的接触焊盘的电子芯片。

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