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1. 发明申请

US20100063346A1 MAGNETORHEOLOGICAL FLUIDS AND THERAPEUTIC USES THEREOF 审中-公开
标题翻译：磁流体流体及其治疗用途
公开(公告)号：US20100063346A1
公开(公告)日：2010-03-11
申请号：US12300843
申请日：2007-05-17
申请人： William J. Murphy , Lisbeth A. Welniak , Cahit Evrensel , Alan Fuchs , Faramarz Gordaninejad
发明人： William J. Murphy , Lisbeth A. Welniak , Cahit Evrensel , Alan Fuchs , Faramarz Gordaninejad
IPC分类号： A61N2/00
CPC分类号： A61K33/26 , A61K38/2013 , A61K41/0052 , A61K45/06
摘要： In some embodiments, the present disclosure provides methods for stimulating a subject's immune system. Particular methods provide a tumor specific immune response by injecting a tumor with a magnetorheological fluid and applying a magnetic field to the tumor. The immune response can be used to treat disseminated tumors or metastatic cells. Further methods induce a general immune response, such as by treating a section of tissue, such as healthy tissue, with a magnetorheological fluid and applying a magnetic field to the treated tissue. The immune response can be used to treat illness or disease or to enhance the effect of a therapeutic agent. In particular examples, the disclosed methods are used to enhance the effect of immuno stimulants. Also provided are methods for causing necrosis of a cell mass, such as a tumor, by injecting a magnetorheological fluid into a section of tissue and applying a magnetic field to the tissue.
摘要翻译：在一些实施方案中，本公开提供了刺激受试者的免疫系统的方法。特定的方法通过用磁流变流体注射肿瘤并向肿瘤施加磁场来提供肿瘤特异性免疫应答。免疫应答可用于治疗弥漫性肿瘤或转移细胞。其它方法诱导一般的免疫应答，例如通过用磁流变流体处理一部分组织，例如健康组织，并向处理的组织施加磁场。免疫应答可用于治疗疾病或疾病或增强治疗剂的作用。在具体实例中，所公开的方法用于增强免疫兴奋剂的效果。还提供了通过将磁流变流体注射到组织的一部分并向组织施加磁场来引起细胞块如肿瘤的坏死的方法。

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