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1. 发明申请

US20060121006A1 Production of nutritional and therapeutic products from cultured animal cells 审中-公开
标题翻译：从培养的动物细胞生产营养和治疗产品
公开(公告)号：US20060121006A1
公开(公告)日：2006-06-08
申请号：US11224676
申请日：2005-09-12
申请人： Michael Chancellor , Brandon Minnery , David Chancellor
发明人： Michael Chancellor , Brandon Minnery , David Chancellor
IPC分类号： A61K35/14 , A61K35/12 , C12N5/06
CPC分类号： A61K35/407 , A23L33/10 , A61K35/32 , A61K35/35 , C12N5/0652
摘要： The present invention describes methods and products involving the use of cultured animal cells as ingredients in nutritional and therapeutic products. Said animal cells are preferably cultured on an industrial scale prior to their incorporation into any of a number of edible, topical, oral, or other products.
摘要翻译：本发明描述了涉及使用培养的动物细胞作为营养和治疗产品中的成分的方法和产品。所述动物细胞优选在其并入多种食用，局部，口服或其它产品中的任一种之前以工业规模培养。

2. 发明申请

US20050238625A1 Muscle-derived cells (MDCs) for promoting and enhancing nerve repair and regeneration 有权
标题翻译：用于促进和增强神经修复和再生的肌源性细胞（MDC）
公开(公告)号：US20050238625A1
公开(公告)日：2005-10-27
申请号：US10832542
申请日：2004-04-26
申请人： Michael Chancellor , Johnny Huard , Brandon Minnery
发明人： Michael Chancellor , Johnny Huard , Brandon Minnery
IPC分类号： A61K35/12 , A61K35/34 , A61P25/00 , C12N5/077 , A61K48/00 , C12N5/08
CPC分类号： C12N5/0658 , A61K35/12 , A61K35/34
摘要： The present invention describes methods involving the use of muscle derived cells (MDCs), preferably obtained from skeletal muscle, to support the innervation and repair of damaged tissues and organs, particularly associated with nerve damage or neuropathy. The invention relates to MDCs for use in methods for promoting or enhancing innervation of nerve cells, particularly in the peripheral nervous system, and their ability to contribute to the development of neuronal tissue when MDCs are introduced at or near a tissue or organ site in need of repair due to injury, damage, disease, or dysfunction. Such methods are useful for the treatment of central and peripheral nervous system disorders and to alleviate, abate, or eliminate the symptoms of neurologic or neurodegenerative diseases in animals, particularly mammals, including humans. The methods are also useful for treating both nerve and muscle tissue following injury, damage, or dysfunction to these tissue types.
摘要翻译：本发明描述了使用优选从骨骼肌获得的肌肉衍生细胞（MDC）来支持损伤的组织和器官的神经支配和修复，特别是与神经损伤或神经病有关的方法。本发明涉及用于促进或增强神经细胞神经细胞，特别是周围神经系统神经支配的方法中使用的MDC，以及当将MDCs引入到需要的组织或器官部位处或附近时有助于神经元组织发育的能力由于受伤，损伤，疾病或功能障碍引起的修复。这样的方法可用于治疗中枢和周围神经系统疾病并减轻，减轻或消除动物，特别是包括人在内的哺乳动物的神经退行性疾病或神经变性疾病的症状。这些方法对于在损伤，损伤或这些组织类型的功能障碍之后治疗神经和肌肉组织也是有用的。

3. 发明授权

US09617516B2 Muscle-derived cells (MDCs) for promoting and enhancing nerve repair and regeneration 有权
公开(公告)号：US09617516B2
公开(公告)日：2017-04-11
申请号：US10832542
申请日：2004-04-26
申请人： Michael B. Chancellor , Johnny Huard , Brandon Minnery , Chistopher C. Capelli
发明人： Michael B. Chancellor , Johnny Huard , Brandon Minnery , Chistopher C. Capelli
IPC分类号： C12N5/07 , C12N5/071 , C12N5/16 , C12N5/0789 , C12N5/077 , A61K35/34 , A61K35/12
CPC分类号： C12N5/0658 , A61K35/12 , A61K35/34
摘要： The present invention describes methods involving the use of muscle derived cells (MDCs), preferably obtained from skeletal muscle, to support the innervation and repair of damaged tissues and organs, particularly associated with nerve damage or neuropathy. The invention relates to MDCs for use in methods for promoting or enhancing innervation of nerve cells, particularly in the peripheral nervous system, and their ability to contribute to the development of neuronal tissue when MDCs are introduced at or near a tissue or organ site in need of repair due to injury, damage, disease, or dysfunction. Such methods are useful for the treatment of central and peripheral nervous system disorders and to alleviate, abate, or eliminate the symptoms of neurologic or neurodegenerative diseases in animals, particularly mammals, including humans. The methods are also useful for treating both nerve and muscle tissue following injury, damage, or dysfunction to these tissue types.

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