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1. 发明申请

US20050203416A1 Extended, ultrasound real time 2D imaging probe for insertion into the body 审中-公开
标题翻译：扩展，超声实时2D成像探头插入体内
公开(公告)号：US20050203416A1
公开(公告)日：2005-09-15
申请号：US11077521
申请日：2005-03-10
申请人： Bjorn Angelsen , Tonni Johansen
发明人： Bjorn Angelsen , Tonni Johansen
IPC分类号： A61B8/12 , A61B8/14 , G10K11/35
CPC分类号： A61B8/12 , A61B8/4483 , G10K11/355
摘要： An ultrasound probe with a distal probe tip that can be inserted into the body for real time 2D ultrasound imaging from said probe tip, where said 2D image can be both in the forwards direction from the probe tip and at an angle to the probe tip. The ultrasound beam is generated with one of a single element transducer, and an annular array transducer, and scanned laterally through mechanically movement of the array. The mechanical movement is either achieved by rotation of the array via a flexible wire, or through wobbling of the array, for example through hydraulic actuation. The probe can be made flexible or stiff, where the flexible embodiment is particularly interesting for catheter imaging in the heart and vessels, and the stiff embodiment has applications in minimal invasive surgery and other procedures. The probe design allows for low cost manufacturing which allows factory sterilized probes to be disposed after use.
摘要翻译：具有远端探针末端的超声探头，其可以插入到身体中，用于从所述探针尖端进行实时2D超声成像，其中所述2D图像可以在从探针尖端向前的方向上并且与探针尖端成一定角度。超声波束由单个元件换能器和环形阵列换能器中的一个产生，并且通过阵列的机械移动横向扫描。机械运动可以通过阵列经由柔性线的旋转，或者通过阵列的摆动来实现，例如通过液压致动来实现。探针可以制成柔性或刚性，其中柔性实施例对于心脏和血管中的导管成像特别有趣，并且刚性实施例具有最小侵入性外科手术和其它手术中的应用。探头设计允许低成本制造，使得在使用后可以将工厂消毒的探针放置。

2. 发明申请

US20050194865A1 High frequency ultrasound transducers based on ceramic films 有权
标题翻译：基于陶瓷膜的高频超声换能器
公开(公告)号：US20050194865A1
公开(公告)日：2005-09-08
申请号：US11074990
申请日：2005-03-08
申请人： Bjorn Angelsen , Tonni Johansen , Helge Kristiansen
发明人： Bjorn Angelsen , Tonni Johansen , Helge Kristiansen
IPC分类号： B06B1/06 , H02N2/00
CPC分类号： B06B1/0692 , H01L2224/16225 , H01L2224/48091 , H01L2224/73253 , H01L2224/73265 , H01L2924/00014
摘要： A design and a manufacturing method of ultrasound transducers based on films of ferro-electric ceramic material is presented, the transducers being particularly useful for operating at frequencies above 10 MHz. The manufacturing technique can involve tape-casting of the ceramic films, deposition of the ceramic films onto a substrate with thick film printing, sol-gel, or other deposition techniques, where manufacturing methods for load matching layers and composite ceramic layers are described. The designs also involve acoustic load matching layers that provide particularly wide bandwidth of the transducers, and also multi-band operation of the transducers. The basic designs can be used for elements in a transducer array, that provides the frequency characteristics of the single element transducers, for array steering of the focus and possibly also direction of a pulsed ultrasound beam at high frequencies and multi-band frequencies.
摘要翻译：提出了一种基于铁电陶瓷材料薄膜的超声换能器的设计和制造方法，该换能器对于在10MHz以上的频率下工作特别有用。制造技术可以涉及陶瓷膜的流延，用厚膜印刷，溶胶 - 凝胶或其他沉积技术将陶瓷膜沉积到基底上，其中描述了负载匹配层和复合陶瓷层的制造方法。这些设计还涉及提供特别宽的传感器带宽的声学负载匹配层，以及换能器的多频带操作。基本设计可用于传感器阵列中的元件，其提供单个元件换能器的频率特性，用于在高频和多频带频率下的聚焦的阵列转向以及可能的脉冲超声波束的方向。

3. 发明申请

US20050119572A1 Probe for 3-dimensional scanning and focusing of an ultrasound beam 失效
标题翻译：探测三维扫描和聚焦超声波束
公开(公告)号：US20050119572A1
公开(公告)日：2005-06-02
申请号：US10963464
申请日：2004-10-12
申请人： Bjorn Angelsen , Tonni Johansen
发明人： Bjorn Angelsen , Tonni Johansen
IPC分类号： A61B8/12 , A61B8/14 , A61B8/00
CPC分类号： A61B8/12 , A61B8/14 , A61B8/4461 , A61B8/4488 , A61B8/483 , G01S15/894 , G01S15/8993
摘要： An ultrasound probe for three-dimensional scanning and focusing of an ultrasound beam in both an azimuth direction and an elevation direction normal to the azimuth direction. The probe is composed of an ultrasound transducer array which has a linear division of the elements in the azimuth direction for electronic steering of the beam direction and focus in the azimuth direction. The array elements have a coarse division in the elevation direction for electronic steering of the focus in the elevation direction, and possibly small angle direction steering of the beam in the elevation direction for parallel receive and/or transmit beams. Large angle direction scanning of the beam in the elevation direction is obtained by mechanical rotation of the array around an axis. The invention implies useful embodiments for insertion of the probe into the body, through mounting the array at the distal tip of an elongated device.
摘要翻译：一种用于三维扫描和超声波束在方位角方向和垂直于方位方向的仰角方向聚焦的超声波探头。该探头由超声波换能器阵列组成，该阵列具有方位角方向上的元件的线性分割，用于电子方向的光束方向和方位角方向上的焦点。阵列元件在高程方向上具有粗略划分，用于在仰角方向上进行焦点的电子转向，并且可能在垂直方向上对于并行接收和/或发射波束可能的小角度方向转向。通过围绕轴线的阵列的机械旋转获得沿垂直方向的光束的大角度方向扫描。本发明意味着通过将阵列安装在细长装置的远端处，将探针插入体内的有用实施例。

4. 发明申请

US20050182324A1 Methods of estimating ultrasound scatterer parameters in soft tissues 审中-公开
标题翻译：估计软组织超声波散射参数的方法
公开(公告)号：US20050182324A1
公开(公告)日：2005-08-18
申请号：US11030385
申请日：2005-01-06
申请人： Bjorn Angelsen , Tonni Johansen
发明人： Bjorn Angelsen , Tonni Johansen
IPC分类号： A61B8/00
CPC分类号： A61B8/481
摘要： A method for characterizing ultrasound scatterers in soft tissue, wherein scattered signals are used to eliminate the absorption attenuation of an ultrasound wave from estimated parameters and to obtain directional scattering information. The scattered signals are obtained from either multiple regions where one region is used as a reference or multiple scattering directions, creating known reference signals from the same scattering region. The method provides new ultrasound parameters for the characterization and contrast enhancement of tissue structures in ultrasound imaging, such as tumor structures, ischemia of a myocardial wall and/or plaque compositions in vascular atheroma. The method of the invention can be used with various arrangements of ultrasound transducers, particularly switched linear arrays.
摘要翻译：一种用于表征软组织中的超声波散射体的方法，其中使用散射信号来消除来自估计参数的超声波的吸收衰减并获得方向散射信息。从其中一个区域用作参考或多个散射方向的多个区域获得散射信号，从相同的散射区域产生已知的参考信号。该方法为超声成像中的组织结构的表征和对比增强提供了新的超声参数，例如肿瘤结构，心肌壁缺血和/或血管粥样斑块中的斑块组成。本发明的方法可以与超声换能器，特别是切换线性阵列的各种布置一起使用。

5. 发明申请

US20070035204A1 Dual frequency band ultrasound transducer arrays 有权
标题翻译：双频带超声波换能器阵列
公开(公告)号：US20070035204A1
公开(公告)日：2007-02-15
申请号：US11493283
申请日：2006-07-26
申请人： Bjorn Angelsen , Tonni Johansen , Rune Hansen , Svein-Erik Maasoey , Peter Nasholm
发明人： Bjorn Angelsen , Tonni Johansen , Rune Hansen , Svein-Erik Maasoey , Peter Nasholm
IPC分类号： H01L41/00 , H02N2/00
CPC分类号： B06B1/064 , G01S7/52022 , G01S15/8915 , G01S15/8952
摘要： Ultrasound probes that transmits/receives ultrasound pulses with frequencies both in a low frequency (LF) and a high frequency (HF) band, where the radiation surfaces of said HF and LF bands at least have a common region. Several solutions for transmission (and reception) of LF and HF pulses through the same radiation surface are given. The arrays and elements can be of a general type, for example linear phased or switched arrays, or annular arrays or elements with division in both azimuth and elevation direction, like a 1.5D, a 1.75D and a full 2D array. The LF and HF element division and array apertures can also be different.
摘要翻译：用于发送/接收具有低频（LF）和高频（HF）频带的频率的超声波脉冲的超声波探头，其中所述HF和LF频带的辐射表面至少具有公共区域。给出了通过相同辐射表面传输（和接收）LF和HF脉冲的几种解决方案。阵列和元件可以是一般的类型，例如线性相位或开关阵列，或者在方位角和高度方向上划分的环形阵列或元件，如1.5D，1.75D和全2D阵列。 LF和HF元件分割和阵列孔径也可以不同。

6. 发明申请

US20060036176A1 Wide aperture array design with constrained outer probe dimension 有权
标题翻译：宽孔径阵列设计，具有约束的外探头尺寸
公开(公告)号：US20060036176A1
公开(公告)日：2006-02-16
申请号：US10894954
申请日：2004-07-20
申请人： Bjorn Angelsen , Tonni Johansen , Rune Hansen , Peter Naesholm
发明人： Bjorn Angelsen , Tonni Johansen , Rune Hansen , Peter Naesholm
IPC分类号： A61B8/14
CPC分类号： G01S15/894 , A61B8/12 , A61B8/4488 , B06B1/0625 , G01S15/892 , G01S15/8952 , G01S15/8993
摘要： The invention presents solutions for large apertures of an ultrasound array under given dimension constraints given by the application for the ultrasound probe, for example by an endoluminal application. The invention has applications to annular arrays for 2D and 3D imaging, and also to linear or curvilinear arrays for 2D and 3D imaging. The invention further provides large aperture of arrays for dual frequency band operation with large difference between the dual bands.
摘要翻译：本发明针对超声波探针的应用给出的给定尺寸约束，例如通过腔内应用提出了用于超声阵列的大孔径的解决方案。本发明适用于用于2D和3D成像的环形阵列，以及用于2D和3D成像的线性或曲线阵列。本发明还提供了用于双频带操作的大孔径阵列，在双频带之间具有很大差异。

7. 发明申请

US20050054929A1 Ultrasound imaging with syntheric receive aperture and wide aperture, focused transmit beam 有权
标题翻译：超声成像与syntheric接收孔径和宽孔径，聚焦发射束
公开(公告)号：US20050054929A1
公开(公告)日：2005-03-10
申请号：US10932871
申请日：2004-09-02
申请人： Bjorn Angelsen , Tonni Johansen
发明人： Bjorn Angelsen , Tonni Johansen
IPC分类号： A61B8/12 , G01S15/89 , A61B8/00
CPC分类号： A61B8/12 , A61B8/4488 , G01S7/5208 , G01S15/8922 , G01S15/8997
摘要： A method and an instrument for ultrasound imaging using an array of transducer elements which is connected to the instrument with a limited number of wires, where focusing of the transmit beam improves image signal to noise ratio above state of the art methods. This allows the use of higher ultrasound frequencies providing improved image resolution.
摘要翻译：一种用于超声成像的方法和仪器，其使用与有限数量的导线连接到仪器的换能器元件阵列，其中发射束的聚焦提高了现有技术方法的图像信噪比。这允许使用更高的超声频率来提供改进的图像分辨率。

8. 发明授权

US06461303B2 Method of detecting ultrasound contrast agent in soft tissue, and quantitating blood perfusion through regions of tissue 失效
标题翻译：检测软组织超声造影剂的方法，并通过组织区域定量血液灌注
公开(公告)号：US06461303B2
公开(公告)日：2002-10-08
申请号：US09766328
申请日：2001-01-19
申请人： Bjorn Angelsen
发明人： Bjorn Angelsen
IPC分类号： A61B814
CPC分类号： A61B8/06 , A61B8/481 , G01S7/52038 , G01S7/52039
摘要： A method for detection of ultrasound contrast agent in soft tissue according to the present invention includes utilizing an ultrasound transmit beam former and transducer array assembly for transmitting directive, focussed ultrasound pressure pulses with steerable transmit amplitude, transmit aperture, transmit focus, and transmit direction, and with temporal frequency components within a limited band B centered at a frequency f0, towards a region of soft tissue that contains ultrasound contrast agent bubbles. The transmit pulse parameters are arranged, preferably using multiple transmit pulses, so that the incident pressure pulse that is utilized for imaging of the contrast agent for a particular depth, has minimal variation over the actual image range. The non-linearly distorted, back-scattered ultrasound signal is received from both the tissue and the ultrasound contrast agent bubbles with the same ultrasound transducer assembly and the received array element signals are passed through a receiver beamformer that has a steerable spatially directive receiver sensitivity.
摘要翻译：根据本发明的用于检测软组织中的超声造影剂的方法包括利用超声波发射波束形成器和换能器阵列组件来发射具有可控发射振幅，发射孔径，发射焦点和发射方向的定向聚焦超声压力脉冲，并且以在频率f0为中心的有限频带B内的时间频率分量朝向包含超声造影剂气泡的软组织区域。优选地使用多个发射脉冲来布置发射脉冲参数，使得用于特定深度的造影剂成像的入射压力脉冲在实际图像范围上具有最小的变化。使用相同的超声换能器组件从组织和超声造影剂气泡接收非线性变形的反向散射超声信号，并且接收的阵列元件信号通过具有可导向的空间定向接收器灵敏度的接收机波束形成器。

9. 发明授权

US4893628A Dual element ultrasonic transducer probe for combined imaging of tissue structures and blood flow in real time 失效
标题翻译：双元超声波传感器探头可实时组合结构和血流成像
公开(公告)号：US4893628A
公开(公告)日：1990-01-16
申请号：US176881
申请日：1988-04-04
申请人： Bjorn Angelsen
发明人： Bjorn Angelsen
IPC分类号： G01N29/26 , A61B8/06 , G10K11/35
CPC分类号： G10K11/355
摘要： An ultrasonic probe for use in combined and time shared ultrasonic imaging of biological tissue structures together with blood velocity measurements and imaging of blood flow based on the Doppler principle, in which rapid changes of sweep movements of the probe between the respective imaging and measurement modes of operation are performed, said probe having two mechanically steerable ultrasonic beams, comprising:a linear motion electric drive motor having a stationary magnet means and a coil assembly which is linearly moveable with respect to said magnet means by the application of electric current to said coil assembly,two ultrasonic transducers for emitting respective ultrasonic beams and disposed to be pivotable around separate axes within separate angular sectors for sweeping the two ultrasonic beams within the two separate angular sectors, respectively,mechanical coupling assembly for connecting the linear drive motor to the pivotable transducer elements, converting the linear motion of the motor coil assembly into a limited rotary motion of the transducers within said angular sectors,said mechanical coupling assembly comprising at least three pulleys mounted at a distance from each other, and at least one flexible pulling element trained about and rotatably connecting said at least three pulleys with each other,said ultrasonic transducers being each rotatably connected to a separate one of the pulleys, andsaid motor coil assembly being mechanically connected to said at least one pulling element at a portion thereof lying between two pulleys of said at least three pulleys, whereby reciprocating linear movement of the coil assembly causes said angular sweeping of the transducer elements.

10. 发明申请

US20050203402A1 Digital ultrasound beam former with flexible channel and frequency range reconfiguration 审中-公开
标题翻译：数字超声波束形成器，具有灵活的通道和频率范围重新配置
公开(公告)号：US20050203402A1
公开(公告)日：2005-09-15
申请号：US11054399
申请日：2005-02-09
申请人： Bjorn Angelsen , Tonni Johansen
发明人： Bjorn Angelsen , Tonni Johansen
IPC分类号： A61B8/02 , A61B8/06 , A61B8/12 , G01S7/52 , G10K11/34
CPC分类号： G01S7/52025 , G10K11/341
摘要： A digital ultrasound beam former for ultrasound imaging, that can be configured by a control processor to process the signals from ultrasound transducer arrays with variable number of elements at variable sampling frequencies, where the lowest sampling frequency allows for the highest number of array elements. The maximal number of array elements is reduced in the inverse proportion to the sampling frequency. Parallel coupling of transmit/receive circuits for each element allow adaption of the receive Noise Figure and transmit drive capabilities to variations in the electrical impedance of the array elements.
摘要翻译：一种用于超声成像的数字超声波束成形器，其可以由控制处理器配置以处理来自具有可变采样频率的可变数量的元件的超声换能器阵列的信号，其中最低采样频率允许最大数量的阵列元件。与采样频率成反比例的数组元素的最大数量减少。每个元件的发射/接收电路的并联耦合允许接收噪声系数和发射驱动能力适应阵列元件的电阻抗的变化。

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