专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US11046711B2 Purification of rapamycin derivatives using temperature induced phase separation 有权
公开(公告)号：US11046711B2
公开(公告)日：2021-06-29
申请号：US16806770
申请日：2020-03-02
申请人： Biosensors International Group, Ltd.
发明人： Margaret W. Kayo , Richard S. Fornicola , Ivan Kovacik , Leelakrishna Kondaveti , Aniruddh Singh
IPC分类号： C07D498/18
摘要： The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.

2. 发明申请

US20200261694A1 BI-LUMENAL TUBE CATHETER SUPPORT SYSTEM 审中-公开
公开(公告)号：US20200261694A1
公开(公告)日：2020-08-20
申请号：US16751403
申请日：2020-01-24
申请人： Biosensors International Group, Ltd.
发明人： Eric Jones , Eugene Serina , Roseann Ward , Emilio Crisolo
IPC分类号： A61M25/00 , A61M25/01 , A61M25/09 , A61M29/02
摘要： A catheter having a multilumenal tube surrounded by a slotted hypotube is provided. The catheter has a tube holder that houses the multilumenal tubing and slidably engages the hypotube, and has internal passages configured to receive one of more tubes from the multilumenal tube. The multilumenal tubing separates into one or more tubings, each comprising a lumen, such that the tubings exit the tube holder at different locations. The slotted hypotube slidably engages a key in the tube holder that prevents the multilumenal tubing from rotating relative to the tube holder and the one of more tubings that separate from the multilumenal tubing. Advantages provided by the slotted hypotube/tube holder assembly are described.

3. 发明授权

US10597406B2 Purification of rapamycin derivatives using temperature induced phase separation 有权
公开(公告)号：US10597406B2
公开(公告)日：2020-03-24
申请号：US16224140
申请日：2018-12-18
申请人： Biosensors International Group, Ltd.
发明人： Margaret W. Kayo , Richard S. Fornicola , Ivan Kovacik , Leelakrishna Kondaveti , Aniruddh Singh
IPC分类号： C07D498/18
摘要： The present invention provides methods for obtaining purified rapamycin derivatives, including purified Biolimus A9. A crystalline form of Biolimus A9 is also described.

4. 发明授权

US10576242B2 Bi-lumenal tube catheter support system 有权
公开(公告)号：US10576242B2
公开(公告)日：2020-03-03
申请号：US15578107
申请日：2016-05-27
申请人： Biosensors International Group, Ltd.
发明人： Eric Jones , Eugene Serina , Roseann Ward , Emilio Crisolo
IPC分类号： A61M25/00 , A61M25/01 , A61M25/09 , A61M29/02
摘要： A catheter having a multilumenal tube surrounded by a slotted hypotube is provided. The catheter has a tube holder that houses the multilumenal tubing and slidably engages the hypotube, and has internal passages configured to receive one of more tubes from the multilumenal tube. The multilumenal tubing separates into one or more tubings, each comprising a lumen, such that the tubings exit the tube holder at different locations. The slotted hypotube slidably engages a key in the tube holder that prevents the multilumenal tubing from rotating relative to the tube holder and the one of more tubings that separate from the multilumenal tubing. Advantages provided by the slotted hypotube/tube holder assembly are described.

5. 发明授权

US10456508B2 Drug delivery endovascular stent and method of use 有权
公开(公告)号：US10456508B2
公开(公告)日：2019-10-29
申请号：US15406475
申请日：2017-01-13
申请人： Biosensors International Group, Ltd.
发明人： Douglas R. Savage , John E. Shulze , Ronald E. Betts , Sepehr Fariabi , Shih-Horng Su
IPC分类号： A61L31/16 , A61F2/91 , A61F2/915 , A61L31/02 , A61L31/10 , A61F2/848 , A61F2/82 , A61F2/89
摘要： An improvement in drug-eluting stents, and method of their making, are disclosed. The surface of a metal stent is roughened to have a surface roughness of at least about 20 μin (0.5 μm) and a surface roughness range of between about 300-700 μin (7.5-17.5 μm). The roughened stent surface is covered with a polymer-free coating of a limus drug, to a coating thickness greater than the range of surface roughness of the roughened stent surface.

6. 发明授权

US09802216B2 Automated stent coating apparatus and method 有权
公开(公告)号：US09802216B2
公开(公告)日：2017-10-31
申请号：US15369498
申请日：2016-12-05
申请人： Biosensors International Group, Ltd.
发明人： Ivan Vecerina , Vinh Pham
IPC分类号： B05B12/02 , B05B12/12 , B05D1/02 , B05B13/02 , A61L31/00 , A61F2/915
CPC分类号： B05D1/02 , A61F2/915 , A61F2002/91575 , A61F2002/91583 , A61L31/00 , B05B12/02 , B05B12/122 , B05B12/126 , B05B13/0235 , B05C5/0216 , B05C11/1021 , B05C11/1023 , B05C13/025
摘要： An automated apparatus and method for coating medical devices such as an intravascular stent, are disclosed in the method, a 2-D image of a stent is processed to determine (1) paths along the stent skeletal elements by which a stent secured to a rotating support element can be traversed by a dispenser head whose relative motion with respect to the support element is along the support-element axis, such that some or all of the stent skeletal elements will be traversed (2) the relative speeds of the dispenser head and support element as the dispenser head travels along the paths, and (3), and positions of the dispenser head with respect to a centerline of the stent elements as the dispenser head travels along such paths The rotational speed of the support and relative linear speed of the dispenser are controlled to achieve the desired coating thickness and coating coverage on the upper surfaces, and optionally, the side surfaces, of the stent elements.

7. 发明申请

US20140245952A1 Automated Stent Coating Apparatus and Method 有权
标题翻译：自动支架涂布装置及方法
公开(公告)号：US20140245952A1
公开(公告)日：2014-09-04
申请号：US14042682
申请日：2013-09-30
申请人： Biosensors International Group, Ltd.
发明人： Ivan Vecerina , Vinh Pham
IPC分类号： B05B12/02 , A61L31/00
CPC分类号： B05D1/02 , A61F2/915 , A61F2002/91575 , A61F2002/91583 , A61L31/00 , B05B12/02 , B05B12/122 , B05B12/126 , B05B13/0235 , B05C5/0216 , B05C11/1021 , B05C11/1023 , B05C13/025
摘要： An automated apparatus and method for coating medical devices such as an intravascular stent, are disclosed in the method, a 2-D image of a stent is processed to determine (1) paths along the stent skeletal elements by which a stent secured to a rotating support element can be traversed by a dispenser head whose relative motion with respect to the support element is along the support-element axis, such that some or all of the stent skeletal elements will be traversed (2) the relative speeds of the dispenser head and support element as the dispenser head travels along the paths, and (3), and positions of the dispenser head with respect to a centerline of the stent elements as the dispenser head travels along such paths The rotational speed of the support and relative linear speed of the dispenser are controlled to achieve the desired coating thickness and coating coverage on the upper surfaces, and optionally, the side surfaces, of the stem elements
摘要翻译：在该方法中公开了用于涂覆诸如血管内支架的医疗装置的自动化装置和方法，处理支架的2-D图像以确定（1）沿支架骨架元件的路径，支架固定在旋转支撑元件可以通过相对于支撑元件的相对运动沿着支撑元件轴线的分配器头部移动，使得一些或全部支架骨架元件将被穿过（2）分配器头部的相对速度当分配器头沿着路径行进时的支撑元件，和（3）以及分配器头部相对于支架元件的中心线的位置，因为分配器头沿着这样的路径行进。支撑件的旋转速度和相对线速度控制分配器以在茎元件的上表面和任选的侧表面上实现期望的涂层厚度和涂层覆盖

8. 发明申请

US20140200447A1 MULTI-DIMENSIONAL IMAGE RECONSTRUCTION 审中-公开
标题翻译：多维图像重建
公开(公告)号：US20140200447A1
公开(公告)日：2014-07-17
申请号：US14214960
申请日：2014-03-16
申请人： Biosensors International Group, Ltd.
发明人： Benny Rousso , Michael Nagler
IPC分类号： A61B6/00 , A61M5/00 , A61B19/00
CPC分类号： A61B6/481 , A61B6/4057 , A61B6/4258 , A61B6/486 , A61B6/5217 , A61B6/5241 , A61B90/39 , A61M5/007 , G01T1/161 , G01T1/166
摘要： Apparatus for radiation based imaging of a non-homogenous target area having distinguishable regions therein, comprises: an imaging unit configured to obtain radiation intensity data from a target region in the spatial dimensions and at least one other dimension, and an image four-dimension analysis unit analyzes the intensity data in the spatial dimension and said at least one other dimension in order to map the distinguishable regions. The system typically detects rates of change over time in signals from radiopharmaceuticals and uses the rates of change to identify the tissues. In a preferred embodiment, two or more radiopharmaceuticals are used, the results of one being used as a constraint on the other.
摘要翻译：用于其中具有可区分区域的非均匀目标区域的用于基于辐射的成像的装置包括：成像单元，被配置为从空间维度和至少一个其他维度中的目标区域获得辐射强度数据，以及图像四维分析单元分析空间维度中的强度数据和所述至少一个其他维度，以便映射可区分的区域。该系统通常检测来自放射性药物的信号随时间的变化率，并使用变化率来识别组织。在优选实施方案中，使用两种或更多种放射性药物，一种用于另一种放射性药物的结果。

9. 发明授权

US10548749B2 Vascular stent with a mixed configuration of connectors 有权
公开(公告)号：US10548749B2
公开(公告)日：2020-02-04
申请号：US14307723
申请日：2014-06-18
申请人： Biosensors International Group, Ltd.
发明人： Dan Wang , Koon Kiat Teu , Debashis Dutta , John Shulze
IPC分类号： A61F2/82 , A61F2/90 , A61L31/16 , A61F2/915 , A61L31/02
摘要： This invention provides for a radially expandable stent having superior strength and reduced foreshortening properties. The stents have a mixed configuration of straight and arcuate connector segments that serve to join annular segments that make up the body of the stent. Surprisingly the described mixed configuration provides superior resistance to flip deformation while maintaining desired flexibility.

10. 发明申请

US20180005388A1 SYSTEMS AND METHODS FOR MEDICAL IMAGE REGISTRATION 审中-公开
公开(公告)号：US20180005388A1
公开(公告)日：2018-01-04
申请号：US15546377
申请日：2016-01-26
申请人： BIOSENSORS INTERNATIONAL GROUP, LTD.
发明人： Yoel ZILBERSTIEN , Nathaniel ROTH
IPC分类号： G06T7/32 , G06T7/11 , G06T7/38 , G06T7/13 , A61B6/03 , A61B6/00 , G06T7/00 , G06T7/33
CPC分类号： G06T7/32 , A61B6/032 , A61B6/037 , A61B6/503 , A61B6/5211 , A61B6/5217 , A61B6/5229 , A61B6/5235 , G06T7/0014 , G06T7/11 , G06T7/13 , G06T7/33 , G06T7/344 , G06T7/38 , G06T2200/08 , G06T2200/24 , G06T2207/10016 , G06T2207/10081 , G06T2207/10084 , G06T2207/10104 , G06T2207/10108 , G06T2207/10116 , G06T2207/30048 , G06T2207/30096 , G06T2207/30104
摘要： There is provided a method for registration of intravital anatomical imaging modality image data and nuclear medicine image data of a patient's heart comprising: obtaining anatomical image data including a heart of a patient outputted by an anatomical intravital imaging modality; obtaining at least one nuclear medicine image data outputted by a nuclear medicine imaging modality, the nuclear medicine image data including the heart of the patient; identifying a segmentation of a network of vessels of the heart in the anatomical image data; identifying a contour of at least part of the heart in the nuclear medicine image data, the contour including at least one muscle wall border of the heart; correlating between the segmentation and the contour; registering the correlated segmentation and the correlated contour to form a registered image of the anatomical image data and the nuclear medicine image data; and providing the registered image for display.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式