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1. 发明申请

US20170027685A1 HYDROPHOBIC INTRAOCULAR LENS 审中-公开
标题翻译：疏水性眼内镜
公开(公告)号：US20170027685A1
公开(公告)日：2017-02-02
申请号：US15179250
申请日：2016-06-10
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Adam Reboul
IPC分类号： A61F2/16 , A61L27/16 , C08F220/30
摘要： An intraocular lens (IOL) with excellent non-glistening characteristics comprising at least one copolymer comprising: (a) one or more first monomeric subunits comprising a polymerized acrylate and/or methacrylate group, at least one side group comprising (i) an aryloxy moiety, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized acrylate or methacrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent, (b) one or more second monomeric subunits different from the first monomeric subunits comprising a polymerized acrylate and/or methacrylate group, and comprising at least one alkoxyalkyl side group, (c) one or more third monomeric subunits different from the first and second monomeric subunits, the third monomeric subunits comprising a polymerized acrylate and/or methacrylate group, and comprising at least one alkylene oxide side group, wherein the first monomeric subunit is present in a greater amount by weight than the second monomeric subunit, and the first and second monomeric subunits together comprise about 75 percent or more of the monomeric subunits composition by weight.
摘要翻译：包含至少一种共聚物的眼内透镜（IOL），其包含至少一种共聚物，所述共聚物包含：（a）一种或多种包含聚合的丙烯酸酯和/或甲基丙烯酸酯基团的第一单体亚基，至少一个侧基，其包含（i）芳氧基部分，和（ii）将芳氧基部分与聚合的丙烯酸酯或甲基丙烯酸酯基团连接的脂族碳部分，其中脂族碳部分包含至少一个羟基取代基，（b）与第一单体亚基不同的一个或多个第二单体亚基，其包含聚合的丙烯酸酯和/或甲基丙烯酸酯基团，并且包含至少一个烷氧基烷基侧基，（c）一个或多个不同于第一和第二单体亚基的第三单体亚基，第三单体亚单位包含聚合的丙烯酸酯和/或甲基丙烯酸酯基团，以及包含至少一个环氧烷侧基，其中第一单体亚单位以比th重量更大的量存在 e第二单体亚单位，第一和第二单体亚单位一起占单体重量的约75％或更多。

2. 发明授权

US08835526B2 Polymers for intraocular lenses 有权
标题翻译：眼内透镜聚合物
公开(公告)号：US08835526B2
公开(公告)日：2014-09-16
申请号：US13680755
申请日：2012-11-19
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Jose A. Ors
IPC分类号： G02B1/04 , C08F18/02 , C08F220/26 , C08F220/28 , C08F216/02 , C08L29/10 , A61F2/16 , B29D11/02 , A61L27/16 , C08F22/14 , C08F222/10
CPC分类号： A61L27/00 , A61F2/16 , A61L27/16 , A61L2430/16 , B29D11/023 , C08F22/14 , C08F220/28 , C08F222/1006 , C08F2220/281 , G02B1/041 , C08L33/14
摘要： The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.
摘要翻译：本发明提供用于制造光学部分和眼内透镜的光学部分，眼内透镜和聚合物。光学部分包括包含（a）一种或多种甲基丙烯酸烷氧基烷基酯单体和/或一种或多种掺入聚合物中的丙烯酸烷氧基烷基酯单体的聚合物; （b）一种或多种甲基丙烯酸羟烷基酯单体和/或一种或多种掺入聚合物中的丙烯酸羟烷基酯单体; 和（c）任选地，引入聚合物中的一种或多种交联剂。

3. 发明申请

US20020058724A1 Contact lens of high water content and high water balance 有权
公开(公告)号：US20020058724A1
公开(公告)日：2002-05-16
申请号：US09899043
申请日：2001-07-06
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Jose A. Ors
IPC分类号： C08K003/00
CPC分类号： G02B1/04 , C08F220/28 , C08F220/32 , G02B1/043 , Y10S525/937 , C08L33/10 , C08L33/14 , C08L39/04
摘要： A contact lens of high water content and extremely high water balance made of a homopolymer or copolymer of 2,3-dihydroxypropyl methacrylate and methods of making such contact lenses, and polymers and hydrogels useful in such contact lenses.

4. 发明授权

US09919487B2 Mandrel for holding an intraocular lens blank and method of making an intraocular lens using the same 有权
公开(公告)号：US09919487B2
公开(公告)日：2018-03-20
申请号：US14786836
申请日：2014-04-22
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Andrew Larson
IPC分类号： B29D11/00 , B29D11/02 , B23C3/00 , B23Q3/08
CPC分类号： B29D11/00942 , B23C3/00 , B23Q3/086 , B29D11/023
摘要： A mandrel (300) for holding an intraocular lens blank (200) during manufacturing includes an intraocular lens holding section configured to hold an intraocular lens, the intraocular lens holding section including: a central cavity (310) configured to hold a mounting material (315) such that the mounting material contacts an optic of the intraocular lens blank when the intraocular lens blank is mounted on the mandrel, and a projection (325) extending around a periphery of the central cavity, the projection having an outer wall (330) and an inner wall (335), and the projection being configured such that an outer peripheral edge of the intraocular lens blank extends up to or beyond the projection when the intraocular lens blank is mounted on the mandrel. A second mounting material (320) is deposited in the first trench (340) and then the haptic is milled using e.g. an end mill (365).

5. 发明申请

US20020027302A1 Intraocular lens 有权
标题翻译：人工晶状体
公开(公告)号：US20020027302A1
公开(公告)日：2002-03-07
申请号：US09874015
申请日：2001-06-06
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Jose A. Ors
IPC分类号： B29D011/00
CPC分类号： A61F2/16 , A61L27/16 , A61L2430/16 , C08L33/12 , G02B1/043 , Y10S623/901 , Y10S623/926 , A61L27/52 , C08L33/14
摘要： A one-piece intraocular lens formed from a copolymer of a hydrophilic monomer and an alkoxy-alkylmethacrylate. The intraocular lens is foldable so as to be insertable through a small incision in the eye.
摘要翻译：由亲水性单体和甲氧基烷基甲基丙烯酸烷基酯的共聚物形成的单件眼内透镜。眼内透镜是可折叠的，以便可以通过眼睛中的小切口插入。

6. 发明授权

US09517290B2 Polymers for intraocular lenses 有权
公开(公告)号：US09517290B2
公开(公告)日：2016-12-13
申请号：US14486962
申请日：2014-09-15
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Jose A. Ors
IPC分类号： G02B1/04 , A61L27/00 , A61F2/16 , A61L27/16 , B29D11/02 , C08F220/28 , C08F22/14 , C08F222/10
CPC分类号： A61L27/00 , A61F2/16 , A61L27/16 , A61L2430/16 , B29D11/023 , C08F22/14 , C08F220/28 , C08F222/1006 , C08F2220/281 , G02B1/041 , C08L33/14
摘要： The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.

7. 发明授权

US08854611B2 Method for determining the optic center of a lens blank 有权
标题翻译：用于确定透镜毛坯的光学中心的方法
公开(公告)号：US08854611B2
公开(公告)日：2014-10-07
申请号：US13660670
申请日：2012-10-25
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Andrew Larson , Stephen E. Brauner
IPC分类号： G01B9/00 , B24B13/005 , A61B3/00 , B24B49/12
CPC分类号： A61B3/00 , B24B13/0055 , B24B49/12
摘要： A method comprises providing a lens blank, a precision positioning device, an illumination device, and a vision system, wherein the lens blank includes at least one feature whose position is known relative to a position of an optic center of the lens blank, and wherein the vision system comprises an image sensor and a processor; mounting the lens blank on the precision positioning device; illuminating the lens blank with the illumination device; viewing the lens blank with image sensor of the vision system; determining the position of the at least one feature using the processor; and determining the position of the optic center of the lens blank based on the position of the at least one feature using the processor.
摘要翻译：一种方法包括提供透镜毛坯，精密定位装置，照明装置和视觉系统，其中透镜毛坯包括相对于透镜毛坯的光学中心的位置已知位置的至少一个特征，并且其中视觉系统包括图像传感器和处理器; 将镜头毛坯安装在精密定位装置上; 用照明装置照射镜片毛坯; 用视觉系统的图像传感器观察镜头空白; 使用所述处理器确定所述至少一个特征的位置; 以及基于使用所述处理器的所述至少一个特征的位置来确定所述透镜毛坯的所述光学中心的位置。

8. 发明申请

US20020019455A1 Contact lens of high water content and high water balance 有权
标题翻译：高含水率，高水平衡的隐形眼镜
公开(公告)号：US20020019455A1
公开(公告)日：2002-02-14
申请号：US09871737
申请日：2001-06-04
申请人： Benz Research and Development Corporation
发明人： Patrick H. Benz , Jose A. Ors
IPC分类号： C08K003/00
CPC分类号： G02B1/04 , C08F220/28 , C08F220/32 , G02B1/043 , Y10S525/937 , C08L33/10 , C08L33/14 , C08L39/04
摘要： A contact lens of high water content and extremely high water balance made of a homopolymer or copolymer of 2,3-dihydroxypropyl methacrylate and methods of making such contact lenses, and polymers and hydrogels useful in such contact lenses.
摘要翻译：由甲基丙烯酸2,3-二羟丙基丙酯的均聚物或共聚物制成的高水含量和极高水平衡的隐形眼镜，以及制造这种隐形眼镜的方法，以及可用于这种隐形眼镜的聚合物和水凝胶。

9. 发明申请

US20160101579A1 MANDREL FOR HOLDING AN INTRAOCULAR LENS BLANK AND METHOD OF MAKING AN INTRAOCULAR LENS USING THE SAME 有权
标题翻译：用于保持内窥镜镜片的人造丝及使用其制造内窥镜的方法
公开(公告)号：US20160101579A1
公开(公告)日：2016-04-14
申请号：US14786836
申请日：2014-04-22
申请人： BENZ RESEARCH AND DEVELOPMENT CORPORATION
发明人： Patrick H. BENZ , Andrew Larson
IPC分类号： B29D11/00 , B23Q3/08 , B23C3/00
CPC分类号： B29D11/00942 , B23C3/00 , B23Q3/086 , B29D11/023
摘要： A mandrel (300) for holding an intraocular lens blank (200) during manufacturing includes an intraocular lens holding section configured to hold an intraocular lens, the intraocular lens holding section including: a central cavity (310) configured to hold a mounting material (315) such that the mounting material contacts an optic of the intraocular lens blank when the intraocular lens blank is mounted on the mandrel, and a projection (325) extending around a periphery of the central cavity, the projection having an outer wall (330) and an inner wall (335), and the projection being configured such that an outer peripheral edge of the intraocular lens blank extends up to or beyond the projection when the intraocular lens blank is mounted on the mandrel. A second mounting material (320) is deposited in the first trench (340) and then the haptic is milled using e.g. an end mill (365).
摘要翻译：用于在制造过程中保持眼内透镜毛坯（200）的心轴（300）包括：眼内透镜保持部，被配置为保持眼内透镜;眼内透镜保持部，包括：中心腔（310），其构造成保持安装材料），使得当眼内透镜毛坯安装在心轴上时，安装材料接触眼内透镜毛坯的光学元件，以及围绕中心腔的周边延伸的突起（325），突起具有外壁（330）和内壁（335），并且所述突起被构造成使得当眼内透镜毛坯安装在心轴上时，眼内透镜毛坯的外周边缘向上延伸到或超过突出部。第二安装材料（320）沉积在第一沟槽（340）中，然后使用例如第二沟槽（340）铣削触觉件。立铣刀（365）。

10. 发明申请

US20150061168A1 POLYMERS FOR INTRAOCULAR LENSES 审中-公开
标题翻译：用于内窥镜的聚合物
公开(公告)号：US20150061168A1
公开(公告)日：2015-03-05
申请号：US14486962
申请日：2014-09-15
申请人： Benz Research and Development Corporation
发明人： Patrick H. BENZ , Jose A. ORS
IPC分类号： C08F220/28 , A61L27/16
CPC分类号： A61L27/00 , A61F2/16 , A61L27/16 , A61L2430/16 , B29D11/023 , C08F22/14 , C08F220/28 , C08F222/1006 , C08F2220/281 , G02B1/041 , C08L33/14
摘要： The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.
摘要翻译：本发明提供用于制造光学部分和眼内透镜的光学部分，眼内透镜和聚合物。光学部分包括包含（a）一种或多种甲基丙烯酸烷氧基烷基酯单体和/或一种或多种掺入聚合物中的丙烯酸烷氧基烷基酯单体的聚合物; （b）一种或多种甲基丙烯酸羟烷基酯单体和/或一种或多种掺入聚合物中的丙烯酸羟烷基酯单体; 和（c）任选地，引入聚合物中的一种或多种交联剂。

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