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    • 1. 发明申请
    • MULTILAYER FILMS FOR DELIVERY OF FLAVOR
    • 用于输送花瓣的多层薄膜
    • US20130101652A1
    • 2013-04-25
    • US13806535
    • 2010-06-30
    • Thomas BoydBen GuLeonora Leigh
    • Thomas BoydBen GuLeonora Leigh
    • A61K8/02A61Q11/00
    • A61K8/0233A61K8/02A61K8/731A61K8/8135A61K2800/242A61K2800/244A61Q11/00
    • An oral care composition having enhanced flavor release comprising an orally acceptable carrier containing a first flavor and a multilayer film for extended or delayed flavor release, the multilayer film including at least a center layer containing a second flavor, the center layer positioned between two outer surface layers, each surface layer including a release modulating agent, the first and second flavor being the same or different. The film is adapted to adhere to an oral cavity surface and the outer surface layers may comprise a mucoadhesive polymer, e.g. carboxy polymethylene, polycarbophil or polyvinyl pyrrolidone, and a film forming polymer, eg. hydroxypropylmethyl cellulose (HPMC). Suitable release modulating agents include HPMC and polyvinyl acetate. The carrier may be a toothpaste or mouthwash.
    • 一种具有增强的风味释放的口腔护理组合物,其包含含有第一香料的口腔可接受的载体和用于延长或延迟的香味释放的多层膜,所述多层膜至少包含含有第二香料的中心层,所述中心层位于两个外表面 层,每个表面层包括释放调节剂,第一和第二香料相同或不同。 该膜适于粘附到口腔表面,并且外表面层可以包括粘膜粘附性聚合物,例如, 羧基聚亚甲基,聚卡波非或聚乙烯吡咯烷酮,以及成膜聚合物,例如。 羟丙基甲基纤维素(HPMC)。 合适的释放调节剂包括HPMC和聚乙酸乙烯酯。 载体可以是牙膏或漱口水。
    • 6. 发明申请
    • Oral Compositions and Method for Producing Thereof
    • 口头成分及其制作方法
    • US20130266523A1
    • 2013-10-10
    • US13993719
    • 2010-12-13
    • Ben GuMahmoud Hassan
    • Ben GuMahmoud Hassan
    • A61K8/73A61Q11/00
    • A61K8/731A61K8/922A61Q11/00
    • Methods of preparing a dentifrice comprising polymer matrix film with menthol therein are disclosed. The methods comprise combining a polymer matrix film that comprises hydrophobic additives and is free of a low solubility flavorant such as menthol with a dentifrice base comprising a low solubility flavorant such as menthol and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film and establish an equilibrium of menthol concentration between the polymer matrix film and the dentifrice base. Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed.
    • 公开了制备含有薄荷醇的聚合物基质膜的洁牙剂的方法。 所述方法包括组合包含疏水性添加剂的聚合物基质膜,并且不含低溶解度食用香料如薄荷醇,其中含有低分子量调味剂如薄荷醇的洁牙剂碱,并且将含有低溶解度食用香料的洁牙剂底物保持在组合的聚合物基质膜中 足以使一定量的低溶解度食用香料从包含低溶解度香料的洁牙剂底物转移到聚合物基质膜上,并建立聚合物基质膜和洁牙剂基质之间的薄荷醇浓度的平衡。 还公开了包含低溶解性食用香料的洁牙剂底物中含有低溶解度无味剂的聚合物基质膜的产品。