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1. 发明申请

US20080241214A1 Hydrogel-metal assembly 有权
标题翻译：水凝胶金属组件
公开(公告)号：US20080241214A1
公开(公告)日：2008-10-02
申请号：US12069186
申请日：2008-02-06
申请人： David Myung , Beinn V.O. Mulr , Curtis W. Frank
发明人： David Myung , Beinn V.O. Mulr , Curtis W. Frank
IPC分类号： A61F2/02
CPC分类号： A61L27/34 , A61L27/06 , A61L2400/18 , B32B15/04 , Y10T428/24355 , Y10T428/269 , Y10T428/31536 , Y10T428/31678
摘要： A hydrogel-metal assembly is provided. An intervening polymer network is used to bond together a water-swollen hydrogel layer and a biocompatible surface-modified metallic layer. The hydrogel layer is a water-swollen hydrogel layer of at least two interpenetrating polymers. The surface of the biocompatible surface-modified metallic layer is surface-modified with an inorganic material. The intervening polymer network has been chemically grafted to the inorganic material of the biocompatible surface-modified metallic layer through bi-functional linker molecules. The intervening polymer network is further physically or chemically cross-linked with the polymers of the water-swollen hydrogel. The hydrogel-metal assembly can be adapted to form a medical device, medical implant, an artificial implant, an orthopedic implant, or at least as part of a joint. The hydrogel-metal assembly is attractive for use as such implants or devices due to its characteristics such as, for example, low coefficient of friction, impact-absorption capacity or strength, and/or biocompatibility.
摘要翻译：提供了一种水凝胶 - 金属组件。中间聚合物网络用于将水溶胀的水凝胶层和生物相容的表面改性金属层结合在一起。水凝胶层是至少两个互穿聚合物的水溶胀水凝胶层。生物相容性表面改性金属层的表面用无机材料进行表面改性。中间聚合物网络已经通过双功能连接分子化学接枝到生物相容性表面改性金属层的无机材料上。中间聚合物网络进一步与水溶胀的水凝胶的聚合物物理或化学交联。水凝胶 - 金属组件可以适于形成医疗装置，医疗植入物，人造植入物，矫形植入物，或者至少作为关节的一部分。水凝胶 - 金属组件由于其特性例如低摩擦系数，冲击吸收能力或强度和/或生物相容性而具有吸引力用于这种植入物或装置。

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