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1. 发明申请

US20170128600A1 METHOD FOR IMPROVING HEALTH OUTCOMES 审中-公开
公开(公告)号：US20170128600A1
公开(公告)日：2017-05-11
申请号：US15187484
申请日：2016-06-20
申请人： Avadim Technologies, Inc.
发明人： Stephen T. WOODY
IPC分类号： A61L2/00 , A61Q17/00 , A61Q19/10 , A61K8/19 , A61K8/97
CPC分类号： A61L2/0035 , A61B10/007 , A61K8/19 , A61K8/97 , A61L2/0088 , A61N5/10 , A61N2005/1098 , A61Q17/005 , A61Q19/10
摘要： Method of using an antiseptic and pH modulating solution provides improved health outcomes in part by decolonizing surfaces, animate and inanimate, and improving tissue function and stress response, particularly the barrier properties and antimicrobial properties of tissues, especially skin and muscles, whether damaged or intact and at risk of damage. The method includes initial application followed by continued topical application on a periodic basis until the damaged area is restored or the risk of injury has passed, followed by continued maintenance application for a period of time thereafter. The method of using the solution is believed to restore and improve the functioning of tissues that naturally interrupt pathogenic mechanisms of disease in addition to providing antimicrobial support. The method can be adapted to improve a plurality of health or consumer care outcomes, from preventing or substantially reducing rates of hospital acquired infections to improving muscle performance and recovery, among others.

2. 发明申请

US20180344972A1 METHOD FOR DECOLONIZING MAMMALIAN SKIN 审中-公开
公开(公告)号：US20180344972A1
公开(公告)日：2018-12-06
申请号：US16054017
申请日：2018-08-03
申请人： AVADIM TECHNOLOGIES, INC.
发明人： Stephen T. Woody
IPC分类号： A61M25/00 , A61L2/00
CPC分类号： A61M25/0017 , A61L2/0088 , A61M2025/0019 , A61M2025/0056 , A61M2210/14 , A61M2210/16
摘要： A method for insertion, maintenance, and removal of urethral catheters in mammals including humans includes steps for preventing or reducing the incidence of catheter associated urinary tract infections. In addition to sterile procedures currently practiced or as may be practiced in the future in connection with catheter use, the method includes the steps of applying an antiseptic, zwitterionic, and acidic skincare solution capable of preserving the stratum corneum to the perineum, meatus, and contiguous mucosa surrounding the insertion site before insertion, after insertion, periodically during the period of indwelling, in connection with any incidence of incontinence, and, optionally, before and after removal of the catheter. Application of the solution optionally is continued after catheter removal on a periodic basis until the threat of an infection associated with catheter use has passed, typically at least about five (5) to seven (7) days and up to thirty (30) days. The solution pH is desirably from about 4.4 to 5.5.

3. 发明申请

US20160184220A1 Method for the Prevention and Treatment of Acne 审中-公开
标题翻译：预防和治疗痤疮的方法
公开(公告)号：US20160184220A1
公开(公告)日：2016-06-30
申请号：US14946299
申请日：2015-11-19
申请人： Avadim Technologies, Inc.
发明人： Stephen T. Woody
IPC分类号： A61K9/00 , A61K9/08 , A61K38/02
CPC分类号： A61K9/0014 , A61K8/19 , A61K8/42 , A61K8/64 , A61K9/08 , A61K38/02 , A61K2800/28 , A61K2800/884 , A61Q19/00 , A61Q19/10
摘要： A system for treating and preventing multiple forms of acne includes applying a solution to the skin to assist maintaining the skin's natural acidic mantle of 4.0 to 6.5, preserve moisture transport properties, and maintain specialized lipid content, allowing the skin to function normally, and assisting the skin to heal wounds caused by acne and associated bacterial infections. The method steps include one or more of the following: applying the formulation with surfactants incorporated therein to the skin as a cleanser, rinsing with water; applying the solution, with or without surfactants, and allowing the solution to air dry; repeating the applications and allowing them to air dry throughout the day; and repeating the cleansing and rinsing steps and applying the solution and allowing to air dry before retiring. One or more of the method steps may be repeated on a continual basis, typically daily, for an extended period of time.
摘要翻译：用于治疗和预防多种形式的痤疮的系统包括将溶液施用于皮肤以辅助维持皮肤的天然酸性衣物4.0至6.5，保持水分输送性能，并保持专门的脂质含量，使肌肤正常运作，并协助皮肤由痤疮和相关细菌感染引起的伤口愈合。方法步骤包括以下一个或多个步骤：将其中掺有表面活性剂的制剂施用于作为清洁剂的皮肤，用水冲洗; 施用溶液，有或没有表面活性剂，并使溶液风干; 重复申请，让他们全天候风干; 并重复清洁和漂洗步骤并施加溶液并使其在退火之前风干。一个或多个方法步骤可以连续重复，通常每天重复一段时间。

4. 发明申请

US20160158393A1 Method for Improving Health Outcomes 审中-公开
标题翻译：改善健康成果的方法
公开(公告)号：US20160158393A1
公开(公告)日：2016-06-09
申请号：US14745091
申请日：2015-06-19
申请人： Avadim Technologies, Inc.
发明人： Stephen Thomas Woody
IPC分类号： A61L2/00 , A61M35/00 , A61B10/00 , A61N5/10
CPC分类号： A61L2/0035 , A61B10/007 , A61K8/19 , A61K8/97 , A61L2/0088 , A61N5/10 , A61N2005/1098 , A61Q17/005 , A61Q19/10
摘要： Method of using an antiseptic and pH modulating solution provides improved health outcomes in part by decolonizing surfaces, animate and inanimate, and improving tissue function and stress response, particularly the barrier properties and antimicrobial properties of tissues, especially skin and muscles, whether damaged or intact and at risk of damage. The method includes initial application followed by continued topical application on a periodic basis until the damaged area is restored or the risk of injury has passed, followed by continued maintenance application for a period of time thereafter. The method of using the solution is believed to restore and improve the functioning of tissues that naturally interrupt pathogenic mechanisms of disease in addition to providing antimicrobial support. The method can be adapted to improve a plurality of health or consumer care outcomes, from preventing or substantially reducing rates of hospital acquired infections to improving muscle performance and recovery, among others.
摘要翻译：使用防腐和pH调节溶液的方法部分地通过非殖化表面，生物和无生命的方式提供改善的健康结果，并改善组织功能和应激反应，特别是组织，特别是皮肤和肌肉的屏障性质和抗微生物性质，无论是损坏的还是完整的并有损坏的风险。该方法包括初次应用，然后定期继续局部应用，直到损伤区域恢复或损伤的风险已经过去，随后在此后的一段时间内继续进行维护应用。认为使用该溶液的方法能够恢复和改善除了提供抗微生物支持之外自然中断疾病机理的组织的功能。该方法可以适应于改善多种健康或消费者护理结果，从预防或显着降低医院获得性感染的速率以改善肌肉的表现和恢复等。

5. 发明申请

US20210244785A1 COMPOSITIONS AND METHODS FOR THE ANTISEPTIC TREATMENT OF BIOFILMS ON MAMMALIAN TISSUE 有权
公开(公告)号：US20210244785A1
公开(公告)日：2021-08-12
申请号：US16900863
申请日：2020-06-12
申请人： Avadim Technologies, Inc.
发明人： Stephen Thomas Woody
IPC分类号： A61K36/886 , A61K31/4166 , A61K47/18 , A61K47/26 , A61K47/34 , A61K47/24 , A61K47/02 , A61K47/12 , A61K47/22 , A61K47/10 , A61K9/00 , A61P31/02
摘要： Compositions and methods for providing the hybrid benefit of treating biofilms on the surface of mammalian tissue, especially biofilms that occur in association with chronic wounds and burns, and simultaneously providing an antiseptic cleansing and maintenance of the stratum corneum of the tissue and other tissue surfaces, and an opportunity for the tissue to improve by engaging its own natural barrier and immunological defense properties. The compositions and methods prevent the re-establishment of biofilms by facilitating the reduction or eradication of the pathogen producing the biofilm before the biofilm can be established.

6. 发明授权

US10071052B2 Method for the prevention and treatment of acne 有权
公开(公告)号：US10071052B2
公开(公告)日：2018-09-11
申请号：US14946299
申请日：2015-11-19
申请人： Avadim Technologies, Inc.
发明人： Stephen T. Woody
IPC分类号： A61Q19/00 , A61Q19/10 , A61K9/00 , A61K8/42 , A61K8/64 , A61K8/19 , A61K9/08 , A61K38/02 , A61P17/10
CPC分类号： A61K9/0014 , A61K8/19 , A61K8/42 , A61K8/64 , A61K9/08 , A61K38/02 , A61K2800/28 , A61K2800/884 , A61Q19/00 , A61Q19/10
摘要： A system for treating and preventing multiple forms of acne includes applying a solution to the skin to assist maintaining the skin's natural acidic mantle of 4.0 to 6.5, preserve moisture transport properties, and maintain specialized lipid content, allowing the skin to function normally, and assisting the skin to heal wounds caused by acne and associated bacterial infections. The method steps include one or more of the following: applying the formulation with surfactants incorporated therein to the skin as a cleanser, rinsing with water; applying the solution, with or without surfactants, and allowing the solution to air dry; repeating the applications and allowing them to air dry throughout the day; and repeating the cleansing and rinsing steps and applying the solution and allowing to air dry before retiring. One or more of the method steps may be repeated on a continual basis, typically daily, for an extended period of time.

7. 发明授权

US10046137B2 Method for maintenance of urethral catheters 有权
公开(公告)号：US10046137B2
公开(公告)日：2018-08-14
申请号：US14629320
申请日：2015-02-23
申请人： AVADIM TECHNOLOGIES, INC.
发明人： Stephen Thomas Woody
IPC分类号： A61M25/00 , A61L2/00
摘要： A method for insertion, maintenance, and removal of urethral catheters in mammals including humans includes steps for preventing or reducing the incidence of catheter associated urinary tract infections. In addition to sterile procedures currently practiced or as may be practiced in the future in connection with catheter use, the method includes the steps of applying an antiseptic, zwitterionic, and acidic skincare solution capable of preserving the stratum corneum to the perineum, meatus, and contiguous mucosa surrounding the insertion site before insertion, after insertion, periodically during the period of indwelling, in connection with any incidence of incontinence, and, optionally, before and after removal of the catheter. Application of the solution optionally is continued after catheter removal on a periodic basis until the threat of an infection associated with catheter use has passed, typically at least about five (5) to seven (7) days and up to thirty (30) days. The solution pH is desirably from about 4.4 to 5.5.

8. 发明申请

US20150343172A1 METHOD FOR MAINTENANCE OF URETHRAL CATHETERS 审中-公开
标题翻译： URETHRAL CATHETERS维护方法
公开(公告)号：US20150343172A1
公开(公告)日：2015-12-03
申请号：US14629320
申请日：2015-02-23
申请人： AVADIM TECHNOLOGIES, INC.
发明人： Steven Thomas Woody
IPC分类号： A61M25/00 , A61L2/00
CPC分类号： A61M25/0017 , A61L2/0088 , A61M2025/0019 , A61M2025/0056 , A61M2210/14 , A61M2210/16
摘要： A method for insertion, maintenance, and removal of urethral catheters in mammals including humans includes steps for preventing or reducing the incidence of catheter associated urinary tract infections. In addition to sterile procedures currently practiced or as may be practiced in the future in connection with catheter use, the method includes the steps of applying an antiseptic, zwitterionic, and acidic skincare solution capable of preserving the stratum corneum to the perineum, meatus, and contiguous mucosa surrounding the insertion site before insertion, after insertion, periodically during the period of indwelling, in connection with any incidence of incontinence, and, optionally, before and after removal of the catheter. Application of the solution optionally is continued after catheter removal on a periodic basis until the threat of an infection associated with catheter use has passed, typically at least about five (5) to seven (7) days and up to thirty (30) days. The solution pH is desirably from about 4.4 to 5.5.
摘要翻译：在包括人的哺乳动物中插入，维护和去除尿道导管的方法包括用于预防或减少导尿管相关尿路感染发生率的步骤。除了目前实践或将来可能与导管使用相关的无菌方法之外，该方法还包括以下步骤：将能够将角质层保留在会阴，口腔和/或部分的防腐，两性离子和酸性护肤溶液在插入期间，在留置期间周期性地，与任何失禁发生有关的插入部位周围的连续粘膜，以及任选地，在移除导管之前和之后。在导管移除周期性之后，任选地继续使用该溶液，直到与导管使用相关的感染威胁已经通过，通常至少约五（5）至七（7）天和多达三十（30）天。溶液pH优选为约4.4至5.5。

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