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1. 发明授权

US09107773B2 Conformable therapeutic shield for vision and pain 有权
公开(公告)号：US09107773B2
公开(公告)日：2015-08-18
申请号：US13555056
申请日：2012-07-20
申请人： Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人： Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
IPC分类号： A61F13/12 , A61F9/00 , A61F9/013 , A61F9/04 , A61L27/18 , G02C7/04 , A61F9/008
CPC分类号： G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要： A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

2. 发明授权

US07520609B2 Non-invasive measurement of tear volume systems and methods 有权
标题翻译：泪液体积系统和方法的非侵入性测量
公开(公告)号：US07520609B2
公开(公告)日：2009-04-21
申请号：US11335861
申请日：2006-01-18
申请人： Kuang-Mon Ashley Tuan
发明人： Kuang-Mon Ashley Tuan
IPC分类号： A61B3/10
CPC分类号： A61B3/107 , A61F9/00806 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088
摘要： Devices systems, and methods can measure, diagnose and/or characterize an eye of a patient, including physiologic and optical properties, such as hydration and tear volume in relation to an optical surface of the eye, including topography of a corneal surface of the eye and/or a wavefront elevation map of the eye. The system forms an image of a tear meniscus along an eyelid. The eye can be illuminated so that the meniscus appears as a dark band in the image. Tear volume can be determined by measuring a height across the tear meniscus. The tear volume can be used to determine the optical properties of the tear of the eye and to diagnose conditions of the eye. The patient can be screened for treatment of the eye with refractive surgery using a measured pupil size, hydration and topography and/or wavefront.
摘要翻译：装置系统和方法可以测量，诊断和/或表征患者的眼睛，包括生理和光学性质，例如相对于眼睛的光学表面的水合和泪液体积，包括眼睛的角膜表面的形貌和/或眼睛的波前高程图。该系统沿着眼睑形成泪液半月板的图像。可以照亮眼睛，使得半月板在图像中呈现为暗带。撕裂体积可以通过测量穿过泪液半月板的高度来确定。撕裂体积可用于确定眼睛撕裂的光学性质并诊断眼睛的状况。可以使用测量的瞳孔大小，水合和地形和/或波前来对患者进行屈光手术的眼睛治疗。

3. 发明授权

US08876287B2 Ophthalmic lenses and reduction of accommodative error 有权
标题翻译：眼镜片减少调节误差
公开(公告)号：US08876287B2
公开(公告)日：2014-11-04
申请号：US13318406
申请日：2010-05-03
申请人： Arthur Back , Kuang-mon Ashley Tuan
发明人： Arthur Back , Kuang-mon Ashley Tuan
IPC分类号： G02C7/04 , G02C7/06
CPC分类号： G02C7/041 , G02C7/042 , G02C7/06 , G02C2202/24
摘要： Ophthalmic lenses provide clear visual acuity and present a myopic defocused image to the lens wearer at both near and distant viewing distances. The present lenses are used in methods to reduce ocular accommodative error in lens wearers. Methods of manufacturing the present lenses are described.
摘要翻译：眼睛透镜提供清晰的视力，并且在近距离和远距离观察距离的同时向镜片佩戴者呈现近视散焦图像。本发明的镜片用于减少眼镜佩戴者眼睛调节误差的方法。对本发明的制造方法进行说明。

4. 发明申请

US20140028979A1 METHODS AND APPARATUS TO IDENTIFY EYE COVERINGS FOR VISION 有权
标题翻译：识别眼睛覆盖面的方法和设备
公开(公告)号：US20140028979A1
公开(公告)日：2014-01-30
申请号：US13885135
申请日：2011-10-25
申请人： Eugene De Juan ,Jr. , Yair Alster , Cary J. Reich , Ashley Tuan , Angela K. MacFarlane , Matt Clarke , Brian Levy
发明人： Eugene De Juan ,Jr. , Yair Alster , Cary J. Reich , Ashley Tuan , Angela K. MacFarlane , Matt Clarke , Brian Levy
IPC分类号： G02C7/04 , G02C7/02
CPC分类号： G02C7/047 , A61B3/0025 , A61B3/0041 , A61B3/1005 , A61B3/1015 , A61B3/107 , A61B3/18 , A61F9/00804 , A61F9/00806 , A61F9/04 , A61F2009/00859 , A61F2009/00872 , G02C7/027 , G02C7/04 , G02C7/048 , G02C7/049 , G02C2202/16
摘要： Methods and apparatus can fit coverings to treat eyes. The covering can be identified so as to provide improved flow of tear liquid under the covering. The covering can be identified based on an inner corneal curvature and an outer corneal curvature and one or more of a limbus sag height or a conjunctival sag height. The covering may form a chamber when placed on the eye to pump tear liquid under at least a portion of the covering. The covering may comprise an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The covering may comprise a material having high oxygen permeability, for example silicone, with a wettable coating disposed on at least an upper surface of the coating.
摘要翻译：方法和装置可以配合护理眼睛。可以识别覆盖物，以便在覆盖物下方提供改善的泪液流动。可以基于内部角膜曲率和外部角膜曲率以及角膜缘下垂高度或结膜下垂高度中的一个或多个来识别覆盖物。当覆盖物放置在眼睛上时，该覆盖物可以形成一个室，以在至少一部分覆盖物之下泵送泪液。覆盖物可以包括具有刚性以抵抗角膜上的运动的外部部分和与角膜接触的内部部分，并提供用于上皮再生的环境。覆盖物可以包括具有高氧渗透性的材料，例如硅树脂，其中可湿性涂层设置在涂层的至少上表面上。

5. 发明申请

US20130070200A1 Conformable Therapeutic Shield for Vision and Pain 有权
公开(公告)号：US20130070200A1
公开(公告)日：2013-03-21
申请号：US13503842
申请日：2010-10-25
申请人： Eugene de Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人： Eugene de Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
IPC分类号： A61F9/00 , G02C7/04
CPC分类号： G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要： A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

6. 发明申请

US20120176582A1 Ophthalmic Lenses And Reduction of Accommodative Error 有权
标题翻译：眼科镜片减少容纳误差
公开(公告)号：US20120176582A1
公开(公告)日：2012-07-12
申请号：US13318406
申请日：2010-05-03
申请人： Arthur Back , Kuang-mon Ashley Tuan
发明人： Arthur Back , Kuang-mon Ashley Tuan
IPC分类号： G02C7/04 , G02C7/06
CPC分类号： G02C7/041 , G02C7/042 , G02C7/06 , G02C2202/24
摘要： Ophthalmic lenses provide clear visual acuity and present a myopic defocused image to the lens wearer at both near and distant viewing distances. The present lenses are used in methods to reduce ocular accommodative error in lens wearers. Methods of manufacturing the present lenses are described.
摘要翻译：眼睛透镜提供清晰的视力，并且在近距离和远距离观察距离的同时向镜片佩戴者呈现近视散焦图像。本发明的镜片用于减少眼镜佩戴者眼睛调节误差的方法。对本发明的制造方法进行说明。

7. 发明授权

US09498385B2 Conformable therapeutic shield for vision and pain 有权
公开(公告)号：US09498385B2
公开(公告)日：2016-11-22
申请号：US13503842
申请日：2010-10-25
申请人： Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela MacFarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人： Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela MacFarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
IPC分类号： A61F13/00 , A61F13/12 , A61F9/00 , A61F9/013 , A61F9/04 , A61L27/18 , G02C7/04 , A61F9/008
CPC分类号： G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要： A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

8. 发明申请

US20120310133A1 Conformable Therapeutic Shield for Vision and Pain 审中-公开
标题翻译：适用于视力和疼痛的治疗盾
公开(公告)号：US20120310133A1
公开(公告)日：2012-12-06
申请号：US13555056
申请日：2012-07-20
申请人： Eugene De Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人： Eugene De Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
IPC分类号： A61F9/00
CPC分类号： G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要： A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
摘要翻译：适形覆盖物包括具有刚性以抵抗角膜上的运动的外部部分和与角膜接触的内部部分并提供用于上皮再生的环境。覆盖物的内部部分可以以许多方式配置，以便至少部分地符合消融的基质表面，以便矫正视力。适形的内部部分可以具有至少一些刚性，以便平滑上皮，使得上皮迅速再生并且被覆盖物引导以形成平滑的视觉层。内部部分可以包括在约1×10 -4 Pa * m 3至约5×10 -4 Pa * m 3的范围内的刚性量，以便至少部分地偏转并符合消融的角膜并使内部部分平滑的消融量在偏转时具有一定的压力。

9. 发明授权

US07866819B2 Non-invasive measurement of tear volume systems and methods 有权
标题翻译：泪液体积系统和方法的非侵入性测量
公开(公告)号：US07866819B2
公开(公告)日：2011-01-11
申请号：US12403229
申请日：2009-03-12
申请人： Kuang-Mon Ashley Tuan
发明人： Kuang-Mon Ashley Tuan
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61B3/107 , A61F9/00806 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088
摘要： Devices systems, and methods can measure, diagnose and/or characterize an eye of a patient, including physiologic and optical properties, such as hydration and tear volume in relation to an optical surface of the eye, including topography of a corneal surface of the eye and/or a wavefront elevation map of the eye. The system forms an image of a tear meniscus along an eyelid. The eye can be illuminated so that the meniscus appears as a dark band in the image. Tear volume can be determined by measuring a height across the tear meniscus. The tear volume can be used to determine the optical properties of the tear of the eye and to diagnose conditions of the eye. The patient can be screened for treatment of the eye with refractive surgery using a measured pupil size, hydration and topography and/or wavefront.
摘要翻译：装置系统和方法可以测量，诊断和/或表征患者的眼睛，包括生理和光学性质，例如相对于眼睛的光学表面的水合和泪液体积，包括眼睛的角膜表面的形貌和/或眼睛的波前高程图。该系统沿着眼睑形成泪液半月板的图像。可以照亮眼睛，使得半月板在图像中呈现为暗带。撕裂体积可以通过测量穿过泪液半月板的高度来确定。撕裂体积可用于确定眼睛撕裂的光学性质并诊断眼睛的状况。可以使用测量的瞳孔大小，水合和地形和/或波前来对患者进行屈光手术的眼睛治疗。

10. 发明授权

US09395558B2 Methods and apparatus to identify eye coverings for vision 有权
标题翻译：识别视力眼罩的方法和装置
公开(公告)号：US09395558B2
公开(公告)日：2016-07-19
申请号：US13885135
申请日：2011-10-25
申请人： Eugene de Juan, Jr. , Yair Alster , Cary J. Reich , Ashley Tuan , Angela K MacFarlane , Matt Clarke , Brian Levy
发明人： Eugene de Juan, Jr. , Yair Alster , Cary J. Reich , Ashley Tuan , Angela K MacFarlane , Matt Clarke , Brian Levy
IPC分类号： A61B3/00 , G02C7/04 , A61B3/18 , G02C7/02 , A61F9/008 , A61B3/10 , A61B3/107 , A61F9/04
CPC分类号： G02C7/047 , A61B3/0025 , A61B3/0041 , A61B3/1005 , A61B3/1015 , A61B3/107 , A61B3/18 , A61F9/00804 , A61F9/00806 , A61F9/04 , A61F2009/00859 , A61F2009/00872 , G02C7/027 , G02C7/04 , G02C7/048 , G02C7/049 , G02C2202/16
摘要： Methods and apparatus can fit coverings to treat eyes. The covering can be identified so as to provide improved flow of tear liquid under the covering. The covering can be identified based on an inner corneal curvature and an outer corneal curvature and one or more of a limbus sag height or a conjunctival sag height. The covering may form a chamber when placed on the eye to pump tear liquid under at least a portion of the covering. The covering may comprise an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The covering may comprise a material having high oxygen permeability, for example silicone, with a wettable coating disposed on at least an upper surface of the coating.
摘要翻译：方法和装置可以配合护理眼睛。可以识别覆盖物，以便在覆盖物下方提供改善的泪液流动。可以基于内部角膜曲率和外部角膜曲率以及角膜缘下垂高度或结膜下垂高度中的一个或多个来识别覆盖物。当覆盖物放置在眼睛上时，该覆盖物可以形成一个室，以在至少一部分覆盖物之下泵送泪液。覆盖物可以包括具有刚性以抵抗角膜上的运动的外部部分和与角膜接触的内部部分，并提供用于上皮再生的环境。覆盖物可以包括具有高氧渗透性的材料，例如硅树脂，其中可湿性涂层设置在涂层的至少上表面上。

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