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1. 发明授权

US06873156B2 Method and apparatus for performing neuroimaging 失效
标题翻译：用于执行神经成像的方法和装置
公开(公告)号：US06873156B2
公开(公告)日：2005-03-29
申请号：US10365952
申请日：2003-02-13
申请人： Craig F. Ferris , Jean A King , Arthur C. Allard , Reinhold Ludwig , Gene Bogdanov
发明人： Craig F. Ferris , Jean A King , Arthur C. Allard , Reinhold Ludwig , Gene Bogdanov
IPC分类号： A61B5/055 , G01R33/28 , G01V3/00
CPC分类号： G01R33/341 , A61B5/0555 , A61B5/4094 , G01R33/34007 , G01R33/34046 , G01R33/3453
摘要： The present invention relates to systems and methods of performing magnetic resonance imaging (MRI) in awake animals. The invention utilizes head and body restrainers to position an awake animal relative to a radio frequency dual coil system operating in a high field magnetic resonance imaging system to provide images of high resolution without motion artifact.
摘要翻译：本发明涉及在清醒动物中进行磁共振成像（MRI）的系统和方法。本发明利用头部和身体限制器相对于在高场磁共振成像系统中操作的射频双线圈系统来定位清醒动物，以提供高分辨率的图像而不产生运动伪像。

2. 发明授权

US06711430B1 Method and apparatus for performing neuroimaging 失效
标题翻译：用于执行神经成像的方法和装置
公开(公告)号：US06711430B1
公开(公告)日：2004-03-23
申请号：US09694087
申请日：2000-10-20
申请人： Craig F. Ferris , Jean A King , Arthur C. Allard , Reinhold Ludwig , Gene Bogdanov
发明人： Craig F. Ferris , Jean A King , Arthur C. Allard , Reinhold Ludwig , Gene Bogdanov
IPC分类号： A61B5055
CPC分类号： A61B5/0555 , A61B5/0042 , A61B2503/40
摘要： The present invention relates to systems and methods of performing magnetic resonance imaging (MRI) in awake animals. The invention utilizes head and body restrainers to position an awake animal relative to a radio frequency dual coil system operating in a high field magnetic resonance imaging system to provide images of high resolution without motion artifact.
摘要翻译：本发明涉及在清醒动物中进行磁共振成像（MRI）的系统和方法。本发明利用头部和身体限制器相对于在高场磁共振成像系统中操作的射频双线圈系统来定位清醒动物，以提供高分辨率的图像而不产生运动伪像。

3. 发明授权

US07343194B2 Method and apparatus for performing neuroimaging 失效
标题翻译：用于执行神经成像的方法和装置
公开(公告)号：US07343194B2
公开(公告)日：2008-03-11
申请号：US10409625
申请日：2003-04-08
申请人： Craig F. Ferris , Arthur C. Allard , Reinhold Ludwig , Gene Bogdanov
发明人： Craig F. Ferris , Arthur C. Allard , Reinhold Ludwig , Gene Bogdanov
IPC分类号： A61B5/05
CPC分类号： A61B5/0555
摘要： In one aspect, a restraining assembly for an awake animal within a magnetic resonance imaging (MRI) device is provided and includes a body restrainer having a first part and a second part that hold a body of the awake animal therebetween. The assembly is of a dual coil design in that it has a volume coil for generating an excitation RF signal and an RF surface coil for receiving an RF response from the animal. The assembly further includes components that serve to restrain movements of the animal, thereby eliminating motion artifacts during the MRI procedure. For example, the assembly preferably includes an adjustable hip holder that has a first section that seats against and applies a restraining force to a buttocks/hip area of the animal and a second section that is adjustably coupled to a pivoting member that is attached to the first section of the body restrainer such that the hip holder is adjustable in both a longitudinal direction along a length of the body restrainer and an up/down direction within the body restrainer between the first and second parts thereof. The pivoting member having features that permit the hip holder to be locked in a desired location so that a sufficient restraining force is applied the animal.
摘要翻译：一方面，提供了一种用于在磁共振成像（MRI）装置内的清醒动物的约束组件，并且包括具有第一部分和第二部分的身体限制器，该第一部分和第二部分将醒来动物的身体保持在其间。组件是双线圈设计，其具有用于产生激励RF信号的体积线圈和用于从动物接收RF响应的RF表面线圈。组件还包括用于抑制动物运动的组件，从而消除MRI过程期间的运动伪影。例如，组件优选地包括可调节的髋部保持器，其具有抵靠并施加约束力到动物的臀部/臀部区域的第一部分，以及可调节地联接到枢转构件的第二部分，身体限制器的第一部分，使得臀部保持器沿着身体限制器的长度在纵向方向上可调节，并且在身体限制器之间的上/下方向之间可调节其第一和第二部分之间。枢转构件具有允许臀部保持器锁定在期望位置的特征，使得动物施加足够的约束力。

4. 发明授权

US06275723B1 Method and apparatus for performing neuroimaging 失效
标题翻译：用于执行神经成像的方法和装置
公开(公告)号：US06275723B1
公开(公告)日：2001-08-14
申请号：US09169602
申请日：1998-10-09
申请人： Craig F. Ferris , Jean A. King , Arthur C. Allard
发明人： Craig F. Ferris , Jean A. King , Arthur C. Allard
IPC分类号： A61B5055
CPC分类号： A61B5/0555 , A61B5/0042
摘要： The present invention relates to a restraining assembly used in neuroimaging of animals in magnetic resonance imaging (MRI) systems. The body of the animal under study is secured within a tube with a head holder to reduce motion artifacts, particularly when the animal is awake. The tube is placed in the bore of the MRI system to conduct imaging procedures with a radio frequency coil adjacent to the animals' head.
摘要翻译：本发明涉及在磁共振成像（MRI）系统中用于动物神经成像的约束组件。正在研究的动物的身体固定在具有头部保持器的管内以减少运动伪像，特别是当动物清醒时。将管放置在MRI系统的孔中，以与动物头部相邻的射频线圈进行成像过程。

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