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    • 3. 发明申请
    • Methods of preservation
    • 保存方法
    • US20130136832A1
    • 2013-05-30
    • US13065972
    • 2011-04-04
    • Anthony Joseph SawyerRichard F. Stockel
    • Anthony Joseph SawyerRichard F. Stockel
    • A23L3/3544C07C229/00C07D233/54C07D209/04A23L3/3526C07C229/26
    • A23L3/3526A23L3/3508A23L3/3544C07D209/04C07D233/54
    • This invention discloses a method of preservation of a food product comprising the step of adding 1) a first component comprising between 10 ppm and 1% of a biocidal salt of Nα—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule with an anionic counterion, and 2) a second component comprising from 10 ppm to 1% by weight an acyl monoglyceride, directly to a food product. The preferred cationic biocidal molecule comprises Nα-lauroyl-L-arginine ethyl ester (“LAE”). The invention also discloses the method of preservation of a food product using salts of a Nα—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and an anionic counterion with or without a monoglyceride of a fatty acid, whereby the packaging film is compounded with the salts and the optional monoglyceride of a fatty acid.
    • 本发明公开了一种保存食品的方法,包括以下步骤:加入1)包含10ppm至1%的Nalpha-(C1-C22)烷酰基二碱性氨基酸烷基(C1- C22)具有阴离子抗衡离子的酯阳离子杀生物分子,和2)包含10ppm至1重量%的酰基单甘油酯的第二组分,直接与食品接触。 优选的阳离子杀生物分子包括Nalpha-月桂酰-L-精氨酸乙酯(“LAE”)。 本发明还公开了使用Nalpha-(C1-C22)烷酰基二碱性氨基酸烷基(C1-C22)酯阳离子杀生物分子的盐和具有或不具有单酸甘油酯的阴离子抗衡离子的食品来保存食品的方法 脂肪酸,由此将包装膜与脂肪酸的盐和任选的甘油单体混合。
    • 4. 发明授权
    • Antimicrobial agents
    • 抗微生物剂
    • US08193244B1
    • 2012-06-05
    • US12455197
    • 2009-05-28
    • Richard F. StockelAnthony Joseph Sawyer
    • Richard F. StockelAnthony Joseph Sawyer
    • A61K31/215A61K31/24A61K8/02A01N25/00
    • A61K31/23A01N37/46A61K8/375A61K8/44A61K9/0036A61K31/223A61K2800/10A61K2800/524A61Q19/00A61K2300/00A01N37/02
    • The combination of Nα-long chain alkanoyl di basic amino acid alkyl ester salts with glycerol monofatty acid esters results in biocidal synergy and the extension of cidal activity of the di basic amino acid derivative for a variety of antimicrobial applications like oral care, wound care, dermatological care, animal care, and cosmetic applications.Nα-C8-C14-long chain alkanoyl-L-arginine alkyl (C1-C4 short chain) ester salts with glycerol monofatty acid esters (C8-C14) are very effective as antimicrobial agents for hospital use particularly as a coating for surgical drapes, covers, walls, trays, table tops, gurneys, or the like. Other uses include the treatment of HSV-1 (fever sore) and as a microbicide when using the combination of the di basic amino acid ester derivative with glycerol monofatty acid esters for preventing HIV and STD's.
    • Nα-长链烷酰基二碱性氨基酸烷基酯盐与甘油单脂肪酸酯的组合导致了杀生物的协同作用和二碱性氨基酸衍生物的杀螨活性的延长,用于各种抗微生物应用,如口腔护理,伤口护理, 皮肤病护理,动物护理和化妆品应用。 具有甘油单脂肪酸酯(C8-C14)的Nα-C8-C14-长链烷酰基-L-精氨酸烷基(C1-C4短链)酯盐作为用于医院用途的抗微生物剂是非常有效的,特别是作为外科用膜的涂层, 盖子,墙壁,托盘,桌面,轮辋等。 其他用途包括治疗HSV-1(发烧疮),并且当使用二碱性氨基酸酯衍生物与甘油单脂肪酸酯组合以预防HIV和STD时,作为杀微生物剂。