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1. 发明授权

US08138172B2 8-oxoadenine derivatives acting as modulators of TLR7 失效
标题翻译：作为TLR7调节剂的8-氧代腺嘌呤衍生物
公开(公告)号：US08138172B2
公开(公告)日：2012-03-20
申请号：US12305801
申请日：2007-07-03
申请人： Anthony Cook , Tom McInally , Stephen Thom , Hiroki Wada
发明人： Anthony Cook , Tom McInally , Stephen Thom , Hiroki Wada
IPC分类号： C07D473/18 , A61K31/522 , C07D473/40 , A61P11/06 , A61P37/08 , A61P31/04 , A61P31/08 , A61P31/20
CPC分类号： C07D473/18
摘要： The present invention provides 8-oxoadenine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The 8-oxoadenine derivatives act as modulators of Toll-like Receptor (TLR) 7 and thus may be used in the treatment of asthma, hepatitis, allergic diseases, viral and bacterial infection as well as cancer.
摘要翻译：本发明提供8-氧代腺嘌呤衍生物，其制备方法，含有它们的药物组合物及其在治疗中的用途。 8-氧代腺嘌呤衍生物作为Toll样受体（TLR）7的调节剂，因此可用于治疗哮喘，肝炎，过敏性疾病，病毒和细菌感染以及癌症。

2. 发明授权

US08009591B2 Automatic overlapping areas that flood routing information 有权
标题翻译：自动重叠区域，洪泛路由信息
公开(公告)号：US08009591B2
公开(公告)日：2011-08-30
申请号：US11565608
申请日：2006-11-30
申请人： Alvaro Retana , Russell White , David Anthony Cook , Yi Yang , Madhavi Chandra
发明人： Alvaro Retana , Russell White , David Anthony Cook , Yi Yang , Madhavi Chandra
IPC分类号： H04L12/28
CPC分类号： H04L12/66
摘要： In one embodiment, a method includes receiving on a first communication link at a local router all routing information at a certain level of detail for each router of multiple routers communicating in a first flooding domain. A measure of distance is determined from a particular router in the first flooding domain to the local router. It is determined whether the measure of distance exceeds a threshold. If the measure of distance exceeds the threshold, then summary routing information with less than the certain level of detail is determined for the particular router. Also, certain routing information is sent over a different second communication link at the local router. The certain routing information includes the summary information for the particular router, and all routing information at the certain level of detail for a subset of routers communicating in the first flooding domain, which subset excludes the particular router.
摘要翻译：在一个实施例中，一种方法包括在本地路由器的第一通信链路上以在第一泛洪域中通信的多个路由器的每个路由器的一定详细级别接收所有路由信息。从第一个洪泛域中的特定路由器到本地路由器确定距离的度量。确定距离测量是否超过阈值。如果距离测量值超过阈值，则确定特定路由器具有小于特定级别细节的汇总路由信息。而且，通过本地路由器上的不同的第二通信链路发送某些路由信息。某些路由信息包括特定路由器的摘要信息，以及在第一洪泛域中通信的路由子集的特定级别的所有路由信息，该子集排除特定路由器。

3. 发明申请

US20070079793A1 System and method for avoiding loss of prime in a diesel engine fuel system 审中-公开
标题翻译：用于避免柴油机燃料系统中的燃料损失的系统和方法
公开(公告)号：US20070079793A1
公开(公告)日：2007-04-12
申请号：US11244923
申请日：2005-10-06
申请人： Anthony Cook , James Bradley , Rodney Klinger
发明人： Anthony Cook , James Bradley , Rodney Klinger
IPC分类号： F02M37/08
CPC分类号： F02D17/04 , F02M37/10
摘要： A system and method for avoiding loss of prime in a primed fuel system of a diesel engine (10) that propels a motor vehicle. With the engine running, a control system (14) shuts down the engine when a fuel level sender (20) indicates an incipient risk of the fuel system losing its prime due to insufficient fuel in the tank (16). In one embodiment, the engine cannot be re-started until more fuel is added to the tank. Another feature allows engine re-starting and limited running after a shut-down by first turning the ignition switch (48) to OFF.
摘要翻译：一种用于避免驱动机动车辆的柴油发动机（10）的底漆燃料系统中的原料损失的系统和方法。当发动机运转时，当燃料油位传感器（20）由于油箱（16）中的燃料不足而指示燃料系统失去原油的初期风险时，控制系统（14）关闭发动机。在一个实施例中，直到更多的燃料被添加到罐中才能重新启动发动机。另一个功能是通过首先将点火开关（48）转到OFF（关闭），允许发动机重新启动并关闭后限制运行。

4. 发明申请

US20060264444A1 Substituted indole derivatives for pharmaceutical compositions for treating respiratory diseases 失效
标题翻译：用于治疗呼吸系统疾病的药物组合物的取代吲哚衍生物
公开(公告)号：US20060264444A1
公开(公告)日：2006-11-23
申请号：US10568889
申请日：2004-08-16
申请人： Roger Bonnert , Anthony Cook , Timothy Luker , Rukhsana Mohammed , Stephen Thom
发明人： Roger Bonnert , Anthony Cook , Timothy Luker , Rukhsana Mohammed , Stephen Thom
IPC分类号： A61K31/497 , A61K31/404 , C07D403/02 , C07D209/36
CPC分类号： C07D209/36
摘要： The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders.
摘要翻译：本发明涉及可用作治疗呼吸系统疾病的药物化合物的式（I）的取代的吲哚。

5. 发明申请

US20060004030A1 Pyrimidine derivatives as modulators of chemokine receptor activity 失效
公开(公告)号：US20060004030A1
公开(公告)日：2006-01-05
申请号：US10525495
申请日：2003-08-20
申请人： Mark Ebden , Premji Meghani , Anthony Cook , John Steele , Lal Lashkar Cheema
发明人： Mark Ebden , Premji Meghani , Anthony Cook , John Steele , Lal Lashkar Cheema
IPC分类号： A61K31/513 , C07D43/02 , C07D239/46
CPC分类号： C07D239/56 , C07D239/60 , C07D401/04 , C07D401/12 , C07D403/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12
摘要： Compounds of formula (1), pharmaceutically acceptable salts, solvates and in vivo hydrolysable esters thereof, have activity as pharmaceuticals, in particular as modulators of chemokine receptor (especially CXCR2) activity, and may be in the treatment (therapeutic or prophylactic) of conditions/diseases in human and non-human animals which are exacerbated or caused by excessive or unregulated production of chemokines.

6. 发明申请

US20050081835A1 Internal combustion engine with pressure boosted exhaust gas recirculation 失效
公开(公告)号：US20050081835A1
公开(公告)日：2005-04-21
申请号：US10687163
申请日：2003-10-16
申请人： Gerald Larson , Anthony Cook
发明人： Gerald Larson , Anthony Cook
IPC分类号： F02B3/06 , F02B29/04 , F02D21/08 , F02D23/02 , F02D41/12 , F02M25/07
CPC分类号： F02D41/0065 , F02B3/06 , F02B29/0406 , F02D23/02 , F02D41/12 , F02M26/07 , F02M26/15 , F02M26/27 , F02M26/34 , F02M26/47 , Y02T10/144 , Y02T10/47
摘要： An exhaust gas recirculating system for a turbocharged diesel engine utilizes an electrically driven compression pump to boost exhaust gas pressure before return to the engine induction system. Exhaust gas is drawn from the exhaust system or stack some distance removed and downstream from the outlet from the exhaust turbine, compressed to overcome the intake manifold boost pressure, and returned to the intake system along an extended pipe to cool the gas. The compressor is energized from the vehicle battery during periods of demand for peak pressure demand on the engine thereby recycling recaptured energy from the battery to boost engine output. Exhaust turbine performance during periods of peak loading is also improved.

7. 外观设计

USD657525S1 Conveyor belt scraper 有权
标题翻译：输送带刮板
公开(公告)号：USD657525S1
公开(公告)日：2012-04-10
申请号：US29387317
申请日：2011-03-11
申请人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
设计人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
CPC分类号： B65G45/16

8. 发明授权

US08464858B2 Conveyor belt scraper and system for the same 失效
标题翻译：输送带刮板和系统相同
公开(公告)号：US08464858B2
公开(公告)日：2013-06-18
申请号：US13045151
申请日：2011-03-10
申请人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
发明人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
IPC分类号： B65G45/16
CPC分类号： B65G45/16
摘要： A scraper blade has a tip of hard material and a base of resilient material. The base has at least one concave surface on the front side adjacent to the base and may have an additional concave surface on the back side adjacent to the tip. When the blade is urged against a conveyor belt for removing material, a substantial vertical force created by a significant obstruction on the belt will compress the scraper blade and will cause the blade to deform and move away from the belt until the obstruction has passed. A scraper blade system includes the scraper blade and an adjustment block for holding and adjusting the scraper blade against the conveyor belt.
摘要翻译：刮刀具有硬质材料的尖端和弹性材料的基部。底座在与基座相邻的前侧上具有至少一个凹面，并且在与顶端相邻的背侧上可具有另外的凹面。当叶片被推靠在输送带上以移除材料时，由带上的明显阻塞产生的大的垂直力将压缩刮刀，并且将导致叶片变形并远离带移动直到障碍物通过。刮刀系统包括刮刀和用于将刮刀保持并调节到传送带上的调节块。

9. 外观设计

USD669243S1 Conveyor belt scraper 有权
公开(公告)号：USD669243S1
公开(公告)日：2012-10-16
申请号：US29417795
申请日：2012-04-09
申请人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
设计人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
CPC分类号： B65G45/16

10. 发明申请

US20110220461A1 Conveyor Belt Scraper And System For The Same 失效
标题翻译：输送带刮铲及系统
公开(公告)号：US20110220461A1
公开(公告)日：2011-09-15
申请号：US13045151
申请日：2011-03-10
申请人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
发明人： James B. Kirschner , Bruce T. Cleevely , R. Anthony Cook , William Thomas Bland
IPC分类号： B65G45/16
CPC分类号： B65G45/16
摘要： A scraper blade has a tip of hard material and a base of resilient material. The base has at least one concave surface on the front side adjacent to the base and may have an additional concave surface on the back side adjacent to the tip. When the blade is urged against a conveyor belt for removing material, a substantial vertical force created by a significant obstruction on the belt will compress the scraper blade and will cause the blade to deform and move away from the belt until the obstruction has passed. A scraper blade system includes the scraper blade and an adjustment block for holding and adjusting the scraper blade against the conveyor belt.
摘要翻译：刮刀具有硬质材料的尖端和弹性材料的基部。底座在与基座相邻的前侧上具有至少一个凹面，并且在与顶端相邻的背侧上可具有另外的凹面。当叶片被推靠在输送带上以移除材料时，由带上的明显阻塞产生的大的垂直力将压缩刮刀，并且将导致叶片变形并远离带移动直到障碍物通过。刮刀系统包括刮刀和用于将刮刀保持并调节到传送带上的调节块。

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