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1. 发明授权

US09113796B2 Method and device for adjusting the visualization of volume data of an object 有权
标题翻译：用于调整物体的体数据的可视化的方法和装置
公开(公告)号：US09113796B2
公开(公告)日：2015-08-25
申请号：US13487227
申请日：2012-06-03
申请人： Klaus Engel , Anna Jerebko
发明人： Klaus Engel , Anna Jerebko
IPC分类号： G06K9/00 , A61B6/02 , G06T15/08 , A61B6/03 , A61B6/00 , A61B8/08 , A61B8/13 , A61B8/00
CPC分类号： A61B6/025 , A61B6/03 , A61B6/037 , A61B6/4441 , A61B6/463 , A61B6/466 , A61B6/469 , A61B6/502 , A61B6/5217 , A61B6/5223 , A61B8/0825 , A61B8/13 , A61B8/463 , G06T15/08
摘要： An adjustment of the visualization of volume data of an object as an image with regard to diagnostically relevant medical information relating to the environment of a region under investigation is provided. In the process, at least one slice region is specified in accordance with slice information within the volume data. A first mapping of a value range of the volume data is used for visualizing the at least one slice region on a display. A second mapping different from the first mapping is used for visualizing a region bordering on the at least one slice region on the display.
摘要翻译：提供了关于与正在调查的区域的环境有关的诊断上相关的医学信息作为图像的对象的体数据的可视化的调整。在该过程中，根据卷数据内的切片信息指定至少一个切片区域。卷数据的值范围的第一映射用于可视化显示器上的至少一个片区域。使用与第一映射不同的第二映射来可视化与显示器上的至少一个片区域邻接的区域。

2. 发明授权

US08705690B2 Imaging method with improved display of a tissue region, imaging device, and computer program product 有权
标题翻译：具有改进的组织区域显示，成像装置和计算机程序产品的成像方法
公开(公告)号：US08705690B2
公开(公告)日：2014-04-22
申请号：US13358081
申请日：2012-01-25
申请人： Anna Jerebko , Klaus Engel
发明人： Anna Jerebko , Klaus Engel
IPC分类号： A61B6/04
CPC分类号： A61B6/025 , A61B6/0414 , A61B6/4452 , A61B6/463 , A61B6/469 , A61B6/502 , A61B6/5223 , G06T11/006 , G06T19/00 , G06T2219/028
摘要： An imaging method with an improved display of a tissue region generates a first visualization and a second visualization from projection recordings that were recorded at different angles. A radiologist is enabled to mark a region in the first visualization, which region is displayed by way of the second visualization.
摘要翻译：具有改进的组织区域显示的成像方法从以不同角度记录的投影记录产生第一可视化和第二可视化。放射科医生能够标记第一可视化中的区域，该区域通过第二可视化显示。

3. 发明授权

US08594407B2 Plane-by-plane iterative reconstruction for digital breast tomosynthesis 有权
标题翻译：用于数字乳房断层合成的平面迭代重建
公开(公告)号：US08594407B2
公开(公告)日：2013-11-26
申请号：US13365451
申请日：2012-02-03
申请人： Anna Jerebko , Koen Michielsen , Johan Nuyts
发明人： Anna Jerebko , Koen Michielsen , Johan Nuyts
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T11/006 , G06T2211/424 , G06T2211/436
摘要： A method for digitally reconstructing a 3-dimensional tomosynthesis image by iterative reconstruction, a reconstructor, and a computer program product method are capable of plane-by-plane iterative reconstruction for digital breast tomosynthesis. The reconstruction process is based on a grouped coordinate ascent algorithm where the volume is split into a plurality of patches, wherein all patches are parallel to a surface of a detector. Splitting the volume allows implementing a modified model for image acquisition where the physical movement of the x-ray source is taken into account because each of the patches is updated separately and sequentially. In addition the splitting allows an efficient implementation on a graphical processing unit by reducing memory requirements.
摘要翻译：通过迭代重建数字重建三维断层合成图像的方法，重建器和计算机程序产品方法能够进行数字乳房层析合成的平面迭代重建。重建过程基于分组的坐标上升算法，其中体积被分成多个斑块，其中所有斑块平行于检测器的表面。拆分音量允许实现用于图像采集的修改模型，其中考虑x射线源的物理移动，因为每个补丁被单独和顺序地更新。此外，拆分允许通过减少内存要求在图形处理单元上有效地实现。

4. 发明申请

US20130202168A1 PLANE-BY-PLANE ITERATIVE RECONSTRUCTION FOR DIGITAL BREAST TOMOSYNTHESIS 有权
标题翻译：用于数字乳腺TOMOSYNTHESIS的PLANE-BY-PLANE ITERATIVE REPONSTRUCTION
公开(公告)号：US20130202168A1
公开(公告)日：2013-08-08
申请号：US13365451
申请日：2012-02-03
申请人： ANNA JEREBKO , KOEN MICHIELSEN , JOHAN NUYTS
发明人： ANNA JEREBKO , KOEN MICHIELSEN , JOHAN NUYTS
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/424 , G06T2211/436
摘要： A method for digitally reconstructing a 3-dimensional tomosynthesis image by iterative reconstruction, a reconstructor, and a computer program product method are capable of plane-by-plane iterative reconstruction for digital breast tomosynthesis. The reconstruction process is based on a grouped coordinate ascent algorithm where the volume is split into a plurality of patches, wherein all patches are parallel to a surface of a detector. Splitting the volume allows implementing a modified model for image acquisition where the physical movement of the x-ray source is taken into account because each of the patches is updated separately and sequentially. In addition the splitting allows an efficient implementation on a graphical processing unit by reducing memory requirements.
摘要翻译：通过迭代重建数字重建三维断层合成图像的方法，重建器和计算机程序产品方法能够进行数字乳房层析合成的平面迭代重建。重建过程基于分组的坐标上升算法，其中体积被分成多个斑块，其中所有斑块平行于检测器的表面。拆分音量允许实现用于图像采集的修改模型，其中考虑x射线源的物理移动，因为每个补丁被单独和顺序地更新。此外，拆分允许通过减少内存要求在图形处理单元上有效地实现。

5. 发明申请

US20120257714A1 X-RAY METHOD AND X-RAY SYSTEM FOR MERGING X-RAY IMAGES AND DETERMINING THREE-DIMENSIONAL VOLUME DATA 有权
标题翻译：用于合并X射线图像和确定三维体积数据的X射线方法和X射线系统
公开(公告)号：US20120257714A1
公开(公告)日：2012-10-11
申请号：US13442086
申请日：2012-04-09
申请人： Rainer GRAUMANN , Anna JEREBKO
发明人： Rainer GRAUMANN , Anna JEREBKO
IPC分类号： A61B6/03
CPC分类号： A61B6/5241 , A61B6/025 , A61B6/4441 , A61B6/5205
摘要： Three-dimensional image information is generated of a body part that is larger than the visual field of an X-ray machine. An X-ray source and an X-ray detector are disposed at a first position such that the X-ray source and the X-ray detector can record a first projection image of at least a first section of a body part. Then the first projection image is recorded. The X-ray source and the X-ray detector are next disposed at a second position such that the X-ray source and the X-ray detector can record a second projection image of at least a second section of the body part. The second section partially overlaps the first section. The first and second projection images are merged to form a projected image. A three-dimensional volume of the body part is reconstructed from the plurality of projection images.
摘要翻译：生成比X射线机的视场大的身体部位的三维图像信息。 X射线源和X射线检测器设置在第一位置，使得X射线源和X射线检测器可以记录身体部分的至少第一部分的第一投影图像。然后记录第一投影图像。接下来，X射线源和X射线检测器设置在第二位置，使得X射线源和X射线检测器可以记录身体部分的至少第二部分的第二投影图像。第二部分与第一部分重叠。第一和第二投影图像被合并以形成投影图像。从多个投影图像重建身体部位的三维体积。

6. 发明授权

US08135189B2 System and method for organ segmentation using surface patch classification in 2D and 3D images 有权
标题翻译：在2D和3D图像中使用表面贴片分类进行器官分割的系统和方法
公开(公告)号：US08135189B2
公开(公告)日：2012-03-13
申请号：US12243327
申请日：2008-10-01
申请人： Anna Jerebko , Matthias Wolf
发明人： Anna Jerebko , Matthias Wolf
IPC分类号： G06K9/00
CPC分类号： G06T17/20 , G06T7/12 , G06T7/149 , G06T2207/10072 , G06T2207/20081 , G06T2207/20124 , G06T2207/30004
摘要： A method for segmenting organs in digitized medical images includes providing a set of segmented training images of an organ, computing a surface mesh having a plurality of mesh cells that approximates a border of the organ, extracting positive examples of all mesh cells and negative examples in the neighborhood of each mesh cell which do not belong to the organ surface, training from the positive examples and negative examples a plurality of classifiers for outputting a probability of a point being a center of a particular mesh cell, computing an active shape model using a subset of center points in the mesh cells, generating a new shape by iteratively deforming the active shape model to fit a test image, and using the classifiers to calculate a probability of each center point of the new shape being a center of a mesh cell which the classifier was trained to recognize.
摘要翻译：用于在数字化医学图像中分割器官的方法包括提供一组器官的分割训练图像，计算具有近似器官边界的多个网格细胞的表面网格，提取所有网孔细胞的阳性实例和阴性实例不属于器官表面的每个网格单元的邻域，从正面示例和负面示例中训练多个分类器，用于输出点是特定网格单元格的中心的概率，使用网格单元中的中心点的子集，通过迭代地使活动形状模型变形以拟合测试图像来生成新形状，并且使用分类器来计算新形状的每个中心点是网格单元格的中心的概率，分类器被训练认识。

7. 发明申请

US20090092301A1 System and Method for Organ Segmentation Using Surface Patch Classification in 2D and 3D Images 有权
标题翻译：使用2D和3D图像中表面贴片分类进行器官分割的系统和方法
公开(公告)号：US20090092301A1
公开(公告)日：2009-04-09
申请号：US12243327
申请日：2008-10-01
申请人： Anna Jerebko , Matthias Wolf
发明人： Anna Jerebko , Matthias Wolf
IPC分类号： G06K9/00
CPC分类号： G06T17/20 , G06T7/12 , G06T7/149 , G06T2207/10072 , G06T2207/20081 , G06T2207/20124 , G06T2207/30004
摘要： A method for segmenting organs in digitized medical images includes providing a set of segmented training images of an organ, computing a surface mesh having a plurality of mesh cells that approximates a border of the organ, extracting positive examples of all mesh cells and negative examples in the neighborhood of each mesh cell which do not belong to the organ surface, training from the positive examples and negative examples a plurality of classifiers for outputting a probability of a point being a center of a particular mesh cell, computing an active shape model using a subset of center points in the mesh cells, generating a new shape by iteratively deforming the active shape model to fit a test image, and using the classifiers to calculate a probability of each center point of the new shape being a center of a mesh cell which the classifier was trained to recognize.
摘要翻译：用于在数字化医学图像中分割器官的方法包括提供一组器官的分割训练图像，计算具有近似器官边界的多个网格细胞的表面网格，提取所有网孔细胞的阳性实例和阴性实例不属于器官表面的每个网格单元的邻域，从正面示例和负面示例中训练多个分类器，用于输出点是特定网格单元格的中心的概率，使用网格单元中的中心点的子集，通过迭代地使活动形状模型变形以拟合测试图像来生成新形状，并且使用分类器来计算新形状的每个中心点是网格单元格的中心的概率，分类器被训练认识。

8. 发明申请

US20080025592A1 System and Method for Detection of Breast Masses and Calcifications Using the Tomosynthesis Projection and Reconstructed Images 有权
标题翻译：使用Tomosynthesis Projection和重建图像检测乳腺肿块和钙化的系统和方法
公开(公告)号：US20080025592A1
公开(公告)日：2008-01-31
申请号：US11767707
申请日：2007-06-25
申请人： Anna Jerebko , Arun Krishnan , Xiang Zhou
发明人： Anna Jerebko , Arun Krishnan , Xiang Zhou
IPC分类号： G06K9/00
CPC分类号： A61B6/466 , A61B6/03 , A61B6/502 , G06T7/0012 , G06T7/97 , G06T11/005 , G06T2207/10112 , G06T2207/10116 , G06T2207/30068 , G06T2211/436
摘要： A method of detecting breast masses and calcifications in digitized images, includes providing a plurality of 2-dimensional (2D) digital X-ray projectional breast images acquired from different viewing angles, extracting candidate lesions and 2D features from said 2D projectional images, computing spicularity characteristics of said candidate lesions, including location, periodicity, and amplitude, applying learning algorithms to said candidate lesions to predict a probability of malignancy of said lesion, receiving from said learning algorithm a probability map of detections for each breast image, said detections comprising associating pixels with a probability of being associated with a malignancy, creating a synthetic 2D slice for each X-ray image wherein malignant regions are indicated by ellipses on a non-malignant background, and constructing a synthetic 3-dimensional (3D) image volume from said 2D synthetic slices.
摘要翻译：一种在数字化图像中检测乳房肿块和钙化的方法，包括提供从不同视角获取的多个二维（2D）数字X射线投射乳房图像，从所述2D投影图像中提取候选病变和2D特征，计算孢子所述候选病变的特征，包括位置，周期和幅度，将学习算法应用于所述候选病变以预测所述病变的恶性的概率，从所述学习算法接收每个乳腺图像的检测的概率图，所述检测包括关联具有与恶性肿瘤相关联的概率的像素，为每个X射线图像创建合成2D切片，其中恶性区域由非恶性背景上的椭圆表示，以及从所述非恶性背景构建合成的三维（3D）图像体积 2D合成切片。

9. 发明授权

US10028718B2 Accelerated data capture in an x-ray system 有权
公开(公告)号：US10028718B2
公开(公告)日：2018-07-24
申请号：US14958038
申请日：2015-12-03
申请人： Peter Bartl , Anna Jerebko , Tom Weidner
发明人： Peter Bartl , Anna Jerebko , Tom Weidner
IPC分类号： G06K9/00 , A61B6/03 , A61B6/00 , A61B6/02
摘要： Data of a predetermined volume portion of an object under examination is captured by an x-ray system that includes an x-ray source and a detector. The x-ray source is activated to generate x-rays that emerge from the x-ray source, radiate through the volume portion, and after radiating through, impinge on the detector. X-rays impinging on the detector are captured pixel by pixel, in order to capture the data of the predetermined volume portion. With the pixel-by-pixel capture, only a subset of all the pixels of the detector is evaluated.

10. 发明申请

US20170011534A1 GENERATING A SYNTHETIC TWO-DIMENSIONAL MAMMOGRAM 有权
标题翻译：产生合成二维MAMMOGRAM
公开(公告)号：US20170011534A1
公开(公告)日：2017-01-12
申请号：US14792259
申请日：2015-07-06
申请人： Maria Jimena Costa , Anna Jerebko , Michael Kelm , Olivier Pauly , Alexey Tsymbal
发明人： Maria Jimena Costa , Anna Jerebko , Michael Kelm , Olivier Pauly , Alexey Tsymbal
IPC分类号： G06T11/00 , G06T7/00 , G06T7/60 , A61B6/00
CPC分类号： G06T11/003 , A61B6/025 , A61B6/502 , G06T3/0031 , G06T7/0012 , G06T7/11 , G06T7/62 , G06T11/008 , G06T15/08 , G06T2207/10081 , G06T2207/10088 , G06T2207/10112 , G06T2207/10124 , G06T2207/20064 , G06T2207/30068 , G06T2207/30096 , G06T2210/41 , G06T2211/436
摘要： A method for generating a synthetic two-dimensional mammogram with enhanced contrast for structures of interest includes acquiring a three-dimensional digital breast tomosynthesis volume having a plurality of voxels. A three-dimensional relevance map that encodes for the voxels the relevance of the underlying structure for a diagnosis is generated. A synthetic two-dimensional mammogram is calculated based on the three-dimensional digital breast tomosynthesis volume and the three-dimensional relevance map.
摘要翻译：用于产生具有增强的感兴趣结构的对比度的合成二维乳房X线照片的方法包括获取具有多个体素的三维数字乳房断层合成体积。生成用于对体素进行编码的三维相关性图，用于诊断的底层结构的相关性。基于三维数字乳房体层合成量和三维相关性图计算合成二维乳房X线照片。

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