专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07402849B2 Parallel, individually addressable probes for nanolithography 失效
标题翻译：平行，单独寻址的纳米光刻探针
公开(公告)号：US07402849B2
公开(公告)日：2008-07-22
申请号：US11073938
申请日：2005-03-07
申请人： Chang Liu , Ming Zhang , David Andrew Bullen
发明人： Chang Liu , Ming Zhang , David Andrew Bullen
IPC分类号： H01L27/148 , H01L29/768 , H01L31/00 , H01L27/14
CPC分类号： G01R1/073 , G01N2035/1037 , G01Q80/00 , G03F7/0002 , Y10S977/857 , Y10S977/874
摘要： A microfabricated probe array for nanolithography and process for designing and fabricating the probe array. The probe array consists of individual probes that can be moved independently using thermal bimetallic actuation or electrostatic actuation methods. The probe array can be used to produce traces of diffusively transferred chemicals on the substrate with sub-1 micrometer resolution, and can function as an arrayed scanning probe microscope for subsequent reading and variation of transferred patterns.
摘要翻译：用于纳米光刻的微加工探针阵列和用于设计和制造探针阵列的工艺。探针阵列由可以使用热双金属致动或静电致动方法独立移动的各个探针组成。探针阵列可以用于在基底上产生具有亚1微米分辨率的扩散转移的化学物质的痕迹，并且可以用作扫描探针显微镜，用于随后读取和改变转印图案。

2. 发明授权

US06867443B2 Parallel, individually addressable probes for nanolithography 失效
标题翻译：平行，单独寻址的纳米光刻探针
公开(公告)号：US06867443B2
公开(公告)日：2005-03-15
申请号：US10647724
申请日：2003-08-25
申请人： Chang Liu , Ming Zhang , David Andrew Bullen
发明人： Chang Liu , Ming Zhang , David Andrew Bullen
IPC分类号： B81B3/00 , B81B7/04 , G01N35/10 , G01Q60/38 , G01Q70/16 , G01Q70/18 , G01Q80/00 , G03F7/00 , G03F7/20 , H01L21/027 , H01L27/148 , H01L29/768
CPC分类号： G01R1/073 , G01N2035/1037 , G01Q80/00 , G03F7/0002 , Y10S977/857 , Y10S977/874
摘要： A microfabricated probe array for nanolithography and process for designing and fabricating the probe array. The probe array consists of individual probes that can be moved independently using thermal bimetallic actuation or electrostatic actuation methods. The probe array can be used to produce traces of diffusively transferred chemicals on the substrate with sub-1 micrometer resolution, and can function as an arrayed scanning probe microscope for subsequent reading and variation of transferred patterns.
摘要翻译：用于纳米光刻的微加工探针阵列和用于设计和制造探针阵列的工艺。探针阵列由可以使用热双金属致动或静电致动方法独立移动的各个探针组成。探针阵列可以用于在基底上产生具有亚1微米分辨率的扩散转移的化学物质的痕迹，并且可以用作扫描探针显微镜，用于随后读取和改变转印图案。

3. 发明授权

US07247895B2 Electrostatic nanolithography probe actuation device and method 失效
标题翻译：静电纳米光刻探头致动装置及方法
公开(公告)号：US07247895B2
公开(公告)日：2007-07-24
申请号：US11377629
申请日：2006-03-16
申请人： Chang Liu , David Andrew Bullen
发明人： Chang Liu , David Andrew Bullen
IPC分类号： H01L27/148 , H01L29/768
CPC分类号： G01Q70/06 , G01Q70/16 , G01Q80/00 , G03F7/0002
摘要： Method and apparatus for selectively actuating a cantilevered probe for applying a compound to a substrate in nanolithography. A probe having a probe electrode and a substrate having a counter electrode are provided. Voltage applied to the probe electrode and/or counter electrode provides electrostatic attraction between them, moving a probe tip into sufficient proximity to the substrate to apply the patterning compound. Alternatively, a flexible cantilevered probe anchored to a holder includes a layer of conductive material forming a probe electrode. A counter electrode on the holder faces the probe electrode. The holder and probe are positioned so that a probe tip applies the compound to the substrate. The probe is disposed between the substrate and the counter electrode. An electrostatic attractive force generated between the probe electrode and the counter electrode flexes the probe and lifts the tip away from the substrate to suspend writing.
摘要翻译：用于在纳米光刻中选择性地致动用于将化合物施加到基底的悬臂探针的方法和装置。提供具有探针电极和具有对电极的基板的探针。施加到探针电极和/或对电极的电压在它们之间提供静电吸引，将探针尖端移动到足够接近衬底以施加图案化化合物。或者，固定到保持器的柔性悬臂式探针包括形成探针电极的导电材料层。保持器上的对电极面向探针电极。定位器和探针被定位成使得探针尖端将化合物施加到基底上。探针设置在基板和对置电极之间。在探针电极和对置电极之间产生的静电吸引力使探针弯曲并将尖端远离衬底提升以暂停写入。

4. 发明申请

US20060257934A1 Cell-based assay for the quantitative high throughput screening of gamma-aminobutyric acid-induced halide transport 审中-公开
标题翻译：用于γ-氨基丁酸诱导的卤化物转运的定量高通量筛选的基于细胞的测定
公开(公告)号：US20060257934A1
公开(公告)日：2006-11-16
申请号：US11400990
申请日：2006-04-10
申请人： Svetlana Tertyshnikova , Steven Dworetzky , Andrew Bullen , Joanne Natale , Corinne Griffin , David Weaver
发明人： Svetlana Tertyshnikova , Steven Dworetzky , Andrew Bullen , Joanne Natale , Corinne Griffin , David Weaver
IPC分类号： C40B30/06
CPC分类号： G01N33/5008 , C07K14/43595 , G01N33/5041 , G01N33/6872 , G01N2500/10
摘要： The present invention is directed to a rapid, quantitative screening procedure of γ-aminobutyric acid (GABA)-mediated halide transport in cells with the use of a conventional 384-well fluorescence plate reader (FLIPR). The halide sensor is a novel yellow fluorescent protein (YFP) with mutations at positions 46/148/152 that exhibits bright fluorescence at 37° C.
摘要翻译：本发明涉及使用常规384孔荧光平板读数器（FLIPR）在γ-氨基丁酸（GABA） - 介导的细胞中的转运的快速定量筛选方法。卤化物传感器是一种新型的黄色荧光蛋白（YFP），其在46/148/152位置具有突变，在37°C显示出明亮的荧光。

5. 发明授权

US07241565B2 Liquid interface configurations for automated patch clamp recording 失效
标题翻译：用于自动膜片钳记录的液体界面配置
公开(公告)号：US07241565B2
公开(公告)日：2007-07-10
申请号：US10305828
申请日：2002-11-27
申请人： Andrew Bullen , Charles David Weaver
发明人： Andrew Bullen , Charles David Weaver
IPC分类号： C12Q1/00
CPC分类号： G01N33/48728
摘要： A method of automatically conducting patch clamp testing is provided wherein a liquid interface is utilized. The liquid interface is defined in a liquid suspension between layers of distinct densities such that cells introduced into the liquid suspension float towards the interface. Thus, the cells are locatable relative to the interface.
摘要翻译：提供了一种自动进行膜片钳测试的方法，其中使用液体界面。液体界面限定在不同密度层之间的液体悬浮液中，使得引入液体悬浮液的细胞朝向界面浮动。因此，单元可相对于界面定位。

6. 发明授权

US07182915B2 Pipette configurations and arrays thereof for measuring cellular electrical properties 有权
标题翻译：移液器配置及其阵列用于测量蜂窝电气性能
公开(公告)号：US07182915B2
公开(公告)日：2007-02-27
申请号：US10305801
申请日：2002-11-27
申请人： Andrew Bullen , Charles David Weaver
发明人： Andrew Bullen , Charles David Weaver
IPC分类号： B01L3/02 , G01N1/14
CPC分类号： G01N33/48728 , B01L3/021 , B01L2200/0668 , B01L2200/12 , B01L2300/0645 , G01N33/5005
摘要： The present application is directed to pipette configurations, arrays of the same and methods for using such pipettes and arrays to accomplish electrical measurements, including whole cell and on cell measurements. In one aspect of the present invention, a pipette includes a hollow tubular section having a distal portion and a tip portion. A bubble is formed at the tip and includes an interior chamber in communication with the hollow tubular section at an end adjacent to the bubble portion. The bubble may have a diameter greater than the diameter of an adjacent portion of the hollow tubular section. An aperture is formed between the internal chamber and an exterior surface of the bubble to accommodate seal formation. In a second aspect of the present invention, a method for forming a glass pipette of the present invention is provided which includes the following steps: (1) heating a glass tube, (2) pulling the glass tube to form a blunt tip, (3) heating the blunt tip, and (4) applying back pressure from the tube to form a bubble including an aperture from the blunt tip.
摘要翻译：本申请涉及移液器配置，相同的阵列以及使用这种移液管和阵列来完成电测量的方法，包括全细胞和细胞测量。在本发明的一个方面，移液管包括具有远侧部分和末端部分的中空管状部分。气泡形成在尖端处，并且包括在与气泡部分相邻的端部处与中空管状部分连通的内部室。气泡的直径可以大于中空管状部分的相邻部分的直径。在内部腔和气泡的外表面之间形成一个孔，以适应密封形成。在本发明的第二方面中，提供了一种本发明的玻璃移液管的形成方法，包括以下步骤：（1）加热玻璃管，（2）拉动玻璃管以形成钝头（ 3）加热钝头，（4）从管中施加背压以形成包括钝头的孔的气泡。

7. 发明授权

US06642129B2 Parallel, individually addressable probes for nanolithography 失效
标题翻译：平行，单独寻址的纳米光刻探针
公开(公告)号：US06642129B2
公开(公告)日：2003-11-04
申请号：US10008719
申请日：2001-12-07
申请人： Chang Liu , Ming Zhang , David Andrew Bullen
发明人： Chang Liu , Ming Zhang , David Andrew Bullen
IPC分类号： H01L2120
CPC分类号： G01R1/073 , G01N2035/1037 , G01Q80/00 , G03F7/0002 , Y10S977/857 , Y10S977/874
摘要： A microfabricated probe array for nanolithography and process for designing and fabricating the probe array. The probe array consists of individual probes that can be moved independently using thermal bimetallic actuation or electrostatic actuation methods. The probe array can be used to produce traces of diffusively transferred chemicals on the substrate with sub-1 micrometer resolution, and can function as an arrayed scanning probe microscope for subsequent reading and variation of transferred patterns.
摘要翻译：用于纳米光刻的微加工探针阵列和用于设计和制造探针阵列的工艺。探针阵列由可以使用热双金属致动或静电致动方法独立移动的各个探针组成。探针阵列可以用于在基底上产生具有亚1微米分辨率的扩散转移的化学物质的痕迹，并且可以用作扫描探针显微镜，用于随后读取和改变转印图案。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式