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1. 发明授权

US4898698A Method of casting a porous membrane of polymeric material 失效
标题翻译：浇铸聚合物材料多孔膜的方法
公开(公告)号：US4898698A
公开(公告)日：1990-02-06
申请号：US281021
申请日：1988-12-07
申请人： Thomas A. Tweedle , Oleh Kutowy , Andre Tremblay
发明人： Thomas A. Tweedle , Oleh Kutowy , Andre Tremblay
IPC分类号： B01D67/00 , B29C41/12 , B29C67/20
CPC分类号： B29C67/202 , B01D67/0011 , B01D67/0013 , B01D67/0016 , B01D2325/20 , B29C41/12
摘要： A method of casting porous membranes of polymeric material is provided wherein the membrane has at least one of the following: a more homogeneous active skin layer for separation purposes with a lower molecular weight cut off, a more homogeneous active skin layer with a sharper molecular weight cut off curve, a relatively thinner active skin layer with a relatively greater flux for a given separation of a substance from a solution thereof, and relatively fewer imperfections through the active skin layer. The method comprises casting a layer of a casting solution on to a support, to provide a cast layer of the casting solution thereon with an exposed skin, then progressively submerging the cast layer in a gelation liquid at a relative velocity of at least 15 cm/second, whereby the exposed skin is gently scrubbed with gelation liquid to continuously remove outwardly diffusing solvent therefrom and dissipate exothermic heat, thus causing gelation of at least a stable, more homogeneous active skin layer, with build-up of a solvent boundary layer between the exposed surface of the layer and the gelation liquid minimized.
摘要翻译：提供了一种浇注聚合材料的多孔膜的方法，其中该膜具有以下至少一种：用于分离目的的更均匀的活性表层，较低分子量的切断，更均匀的分子量更高的活性表层截断曲线，相对较薄的活性表层，具有相对较大的通量，用于给定的物质与其溶液的分离，以及相对较少的通过活性表层的缺陷。该方法包括将一层浇铸溶液浇铸到载体上，以在其上提供具有暴露皮肤的浇铸溶液的浇铸层，然后以至少15cm / s的相对速度将流延层逐渐浸入凝胶液中，第二，由此暴露的皮肤用凝胶液缓缓地洗涤，以从外部向外扩散溶剂并消散放热，从而引起至少一个稳定的，更均匀的活性皮肤层的凝胶化，同时在溶剂界面层之间形成暴露的表面和凝胶液最小化。

2. 发明申请

US20060241054A1 Growth hormone-releasing peptides in the treatment of prevention of atherosclerosis and hypercholesterolemia 失效
标题翻译：生长激素释放肽在预防动脉粥样硬化和高胆固醇血症中的应用
公开(公告)号：US20060241054A1
公开(公告)日：2006-10-26
申请号：US10525266
申请日：2003-08-23
申请人： Huy Ong , Sylvie Marleau , Andre Tremblay
发明人： Huy Ong , Sylvie Marleau , Andre Tremblay
IPC分类号： A61K38/08
CPC分类号： A61K38/27 , A61K38/25
摘要： According to the invention there is provided a method of treatment or prophylaxis of atherosclerosis, hypercholesterolemia or a cardiovascular disease associated with atherosclerosis, which method comprises administration of one or more Growth Hormone Releasing Peptides (GHRPs) to a patient in need of such treatment or prophylaxis. There are also provided methods of reducing blood plasma cholesterol levels, as well as methods of modulating the expression of the scavenger receptor CD36 and genes involved in cellular cholesterol efflux.
摘要翻译：根据本发明，提供了治疗或预防动脉粥样硬化，高胆固醇血症或与动脉粥样硬化相关的心血管疾病的方法，该方法包括向需要这种治疗或预防的患者施用一种或多种生长激素释放肽（GHRP）。还提供了降低血浆胆固醇水平的方法，以及调节清道夫受体CD36的表达和参与细胞胆固醇流出的基因的方法。

3. 发明申请

US20050279052A1 Carton orientation system 审中-公开
标题翻译：纸箱定向系统
公开(公告)号：US20050279052A1
公开(公告)日：2005-12-22
申请号：US11080564
申请日：2005-03-16
申请人： Andre Tremblay
发明人： Andre Tremblay
IPC分类号： B65B21/00 , B65B35/56
CPC分类号： B65B43/42 , B65B21/242 , B65G23/00
摘要： There is provided a system for re-orienting erected cartons having an opening through which primary containers, such as bottles or cans, in a “unit” are to be inserted. The erected cartons are adapted to rotate to make the opening accessible to bottle loading equipment only in a manner which ensures that the geometry of the opening is not deformed from that of the originally erected carton.
摘要翻译：提供了一种用于重新定向具有开口的竖立纸箱的系统，通过该开口插入“单位”中的主要容器，例如瓶或罐。竖立的纸箱适于旋转以使得瓶装载设备可接近的开口仅以确保开口的几何形状不会与原始竖立的纸箱的几何形状变形的方式。

4. 发明申请

US20090088725A1 ACCESSORY SLEEVE FOR A MEDICAL DEVICE 审中-公开
标题翻译：医疗器械附件套
公开(公告)号：US20090088725A1
公开(公告)日：2009-04-02
申请号：US11862264
申请日：2007-09-27
申请人： Olivier BATAILLE , Andre TREMBLAY , Stuart KOZLICK
发明人： Olivier BATAILLE , Andre TREMBLAY , Stuart KOZLICK
IPC分类号： A61M25/01 , A61M25/10
CPC分类号： A61M25/0662 , A61M2025/0681 , A61M2025/1013 , A61M2025/1081
摘要： The present invention provides a medical system including a protective sleeve for a medical device having a distal end positionable in a blood vessel, the protective sleeve including a body defining a passage therethrough and a vent in fluid communication with the passage, where at least a portion of the distal end of the medical device is positionable within the passage. An introducer device may be included having a sheath, where the sheath defines a first passage for receiving a portion of the catheter. In addition, the sleeve may be releasably engageable with the introducer device for subsequent insertion of the medical device into the introducer device.
摘要翻译：本发明提供了一种医疗系统，其包括用于医疗装置的保护套筒，其具有可在血管中定位的远端，所述保护套筒包括限定穿过其中的通道的本体和与所述通道流体连通的通气口，其中至少一部分的医疗装置的远端位于通道内。可以包括具有护套的导引器装置，其中护套限定用于接收导管的一部分的第一通道。此外，套筒可以可释放地与导引器装置接合，以便随后将医疗装置插入导引器装置。

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