会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明申请
    • Composition splice variants and methods relating to cancer specific genes and proteins
    • 与癌症特异性基因和蛋白质相关的组合剪接变体和方法
    • US20060160090A1
    • 2006-07-20
    • US10553436
    • 2004-04-12
    • Robert MacinaLeah TurnerYongming SunAlbert Tam
    • Robert MacinaLeah TurnerYongming SunAlbert Tam
    • C12Q1/68G01N33/574C07H21/04C12P21/06C07K14/82C07K16/30
    • C07K14/82C12Q1/6886C12Q2600/112C12Q2600/136G01N33/57415G01N33/57419G01N33/57423G01N33/57434G01N33/57449
    • The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast, colon, lung, ovarian or prostate cancer and non-cancerous disease states in breast, colon, lung, ovarian or prostate, identifying breast, colon, lung, ovarian or prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered normal or cancerous breast, colon, lung, ovarian or prostate tissue for treatment and research.
    • 本发明涉及存在于正常和肿瘤细胞中的新鉴定的核酸分子和多肽,包括核酸和多肽的片段,变体和衍生物。 本发明还涉及本发明多肽的抗体,以及本发明多肽的激动剂和拮抗剂。 本发明还涉及含有本发明的核酸分子,多肽,抗体,激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括识别,诊断,监测,分期,成像和治疗乳腺,结肠,肺,卵巢或前列腺中的乳腺癌,结肠癌,肺癌,卵巢癌或前列腺癌和非癌性疾病状态,鉴别乳腺癌,结肠癌,肺癌,卵巢癌或卵巢癌 前列腺组织,监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗,转基因动物和细胞的产生,以及生产工程化的正常或癌性乳腺癌,结肠癌,肺癌,卵巢癌或前列腺组织用于治疗和研究。