专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4082744A 4-Benzazonine derivatives and process for preparation thereof 失效
标题翻译： 4-苯并噻吩衍生物及其制备方法
公开(公告)号：US4082744A
公开(公告)日：1978-04-04
申请号：US707276
申请日：1976-07-21
申请人： Masao Ikeda , Shigeo Miyamoto , Thutomu Nozawa , Akira Kurobe , Osamu Futsukaichi
发明人： Masao Ikeda , Shigeo Miyamoto , Thutomu Nozawa , Akira Kurobe , Osamu Futsukaichi
IPC分类号： C07D223/14 , C07D225/06 , C07D225/08
CPC分类号： C07D223/14 , C07D225/06 , Y10S514/849
摘要： Novel 4-benzazonine derivatives and their salts, and processes for the preparation thereof are disclosed. These 4-benzazonine derivatives are represented by the following general formula: ##STR1## wherein R stands for --H, --OH or a lower alkoxy group such as --OCH.sub.3, R.sub.1 designates --H or a lower alkyl group such as --CH.sub.3 and --CH.sub.2 CH.sub.3, R.sub.2 indicates --H or a lower alkyl group such as --CH.sub.3, R.sub.3 stands for --H, a linear or branched, saturated or unsaturated alkyl group having 1 to 4 carbon atoms, a mono- or di-hydroxy lower alkyl group such as --CH.sub.2 OH and ##STR2## a saturated cyclic hydrocarbon group having 3 to 6 carbon atoms or a substituted or unsubstituted aromatic hydrocarbon group having 6 to 8 carbon atoms, and R.sub.4 designates --H, --OH or .dbd. 0. These compounds have medicinal effects, especially therapeutic activities on the central nervous system, such as analgesic, antitussive and sedative activities.

2. 发明授权

US4008219A 4-Benzazonine derivatives and process for preparation thereof 失效
标题翻译： 4-苯并氮杂衍生物及其制备方法
公开(公告)号：US4008219A
公开(公告)日：1977-02-15
申请号：US467520
申请日：1974-05-06
申请人： Masao Ikeda , Shigeo Miyamoto , Thutomu Nozawa , Akira Kurobe , Osamu Futsukaichi
发明人： Masao Ikeda , Shigeo Miyamoto , Thutomu Nozawa , Akira Kurobe , Osamu Futsukaichi
IPC分类号： C07D223/14 , C07D225/06
CPC分类号： C07D223/14 , C07D225/06
摘要： Novel 4-Benzazonine derivatives and their salts, and processes for the preparation thereof are disclosed. These 4-benzazonine derivatives are represented by the following general formula: ##STR1## wherein R stands for --H, --OH or a lower alkoxy group such as --OCH.sub.3, R.sub.1 designates --H or a lower alkyl group such as --CH.sub.3 and --CH.sub.2 CH.sub.3, R.sub.2 indicates --H or a lower alkyl group such as --CH.sub.3, R.sub.3 stands for --H, a linear or branched, saturated or unsaturated alkyl group having 1 to 4 carbon atoms, a mono- or di-hydroxy lower alkyl group such as --CH.sub.2 OH and ##STR2## a saturated cyclic hydrocarbon group having 3 to 6 carbon atoms or a substituted or unsubstituted aromatic hydrocarbon group having 6 to 8 carbon atoms, and R.sub.4 designates --H, --OH or = O. These compounds have medicinal effects, especially therapeutic activities on the central nervous system, such as analgesic, antitussive and sedative activities.
摘要翻译：公开了新的4-苯并氮杂衍生物及其盐，以及其制备方法。这些4-苯并氮杂衍生物由以下通式表示：其中R代表-H，-OH或低级烷氧基，例如-OCH 3，R 1表示-H或低级烷基如-CH 3和 - CH 2 CH 3，R 2表示-H或低级烷基如-CH 3，R 3表示-H，直链或支链，饱和或不饱和的具有1至4个碳原子的烷基，一或二羟基低级烷基如作为-CH 2 OH和具有3〜6个碳原子的饱和环状烃基或具有6〜8个碳原子的取代或未取代的芳香族烃基，R4表示-H，-OH或= O.这些化合物具有药效特别是中枢神经系统的治疗活动，如止痛，镇咳和镇静活动。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式