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1. 发明申请

US20100129515A1 FLAVOUR MODULATING SUBSTANCES 审中-公开
标题翻译：挥发性调节物质
公开(公告)号：US20100129515A1
公开(公告)日：2010-05-27
申请号：US11995336
申请日：2006-07-28
申请人： Chris Winkel , Abdelmajid Kaouas , Sylvia N. Noomen , Harry Renes
发明人： Chris Winkel , Abdelmajid Kaouas , Sylvia N. Noomen , Harry Renes
IPC分类号： A23L1/22 , A23L2/56
CPC分类号： C07C335/12 , A23L27/00 , A23L27/204 , A23L27/88
摘要： The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, tobacco products and oral care products, using a flavour modulating substance selected from the group represented by formula (I), edible salts thereof and edible esters thereof. It has been found that these substances are capable imparting highly desirable taste attributes in the products they are incorporated in. In addition said flavour modulating substances are capable of modulating and complementing, the sensory impact of other, taste imparting, substances. Thus, the present substances are advantageously applied in flavour compositions, foodstuffs, tobacco products and oral care products. Typical examples of flavour modulating substances according to the present invention include N-vanillyl urea, N-vanillyl thiourea, N-vanillyl guanidine, N-isovanillyl urea, N-(3-ethoxy-4-hydroxybenzyl) urea, N-(3,4 dimethoxybenzyl) urea, N,N′-divanillyl urea, N,N′-divanillyl thiourea, N-octyl-N′-vanillyl urea, N-octyl-N′-vanillyl thiourea, N-hexyl-N′-vanillyl urea, N-hexyl-N′-vanillyl thiourea, N-decyl-N′-vanillyl urea, N-decyl-N′-vanillyl thiourea, N-benzyl-N′-vanillyl urea, N-benzyl-N′-vanillyl thiourea, edible salts thereof and edible esters thereof.
摘要翻译：本发明的第一方面涉及使用选自式（I）所示的调味剂的物质，食用盐和其食用酯的食品，饮料，烟草制品和口腔护理产品中的风味调节剂。已经发现，这些物质能够赋予它们所掺入的产品中非常理想的味道特性。此外，所述风味调节物质能够调节和补充其它味道赋予物质的感官影响。因此，本发明的物质有利地应用于风味组合物，食品，烟草制品和口腔护理产品中。根据本发明的风味调节物质的典型实例包括N-香草基脲，N-香草基硫脲，N-香兰基胍，N-异钒酰脲，N-（3-乙氧基-4-羟基苄基）脲，N-（3， 4-二甲氧基苄基）脲，N，N'-二苯乙烯基脲，N，N'-二苯乙烯基硫脲，N-辛基-N'-香草基脲，N-辛基-N'-香草基硫脲，N-己基-N'-香草基脲，N-己基-N'-香草基硫脲，N-癸基-N'-香草基脲，N-癸基-N'-香草基硫脲，N-苄基-N'-香草基脲，N-苄基-N'-香草基硫脲，其食用盐和其食用酯。

2. 发明申请

US20120301587A1 Oxalamide Derivative As Umami Flavouring Agent 有权
标题翻译：草酰胺衍生物作为Umami调味剂
公开(公告)号：US20120301587A1
公开(公告)日：2012-11-29
申请号：US13576572
申请日：2011-02-03
申请人： Abdelmajid Kaouas , Cornelis Winkel
发明人： Abdelmajid Kaouas , Cornelis Winkel
IPC分类号： C07D213/56 , A23L1/226
CPC分类号： C07D213/40 , A23L27/2054
摘要： The compound of the formula (1) is novel and is useful in conferring umami taste on consumable compositions, such as foodstuffs and beverages.
摘要翻译：式（1）的化合物是新颖的，并且可用于赋予消费组合物如食品和饮料上的鲜味。

3. 发明申请

US20080199584A1 Flavour Compositions 审中-公开
标题翻译：香精组合物
公开(公告)号：US20080199584A1
公开(公告)日：2008-08-21
申请号：US12065189
申请日：2006-09-04
申请人： Abdelmajid Kaouas , Harry Renes , Chris Winkel
发明人： Abdelmajid Kaouas , Harry Renes , Chris Winkel
IPC分类号： A23L1/226
CPC分类号： A24B15/00 , A23L2/56 , A23L27/202 , A23L27/2022 , A23V2002/00
摘要： The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, pharmaceutics, tobacco products and oral care products, using a flavour modulating substance selected from the group of substances represented by formula (I) or formula (II), edible salts thereof and edible esters thereof: It has been found that these substances are capable imparting highly desirable taste attributes in the products they are incorporated in. In addition said flavour modulating substances are capable of modulating and complementing, the sensory impact of other, taste imparting, substances. Thus, the present substances are advantageously applied in flavour compositions, foodstuffs, pharmaceutics, tobacco products and oral care products. Typical examples of flavour modulating substances according to the present invention include 2-hydroxy-N-(2-hydroxy-2-methylpropyl)-propanamide, N-lactoyl 1-amino-2-propanol, N-lactoyl 2-amino-1-propanol, N-lactoyl 2-amino-2-methylpropanol, N-gluconyl 1-amino-2-methyl-2-propanol, N-gluconyl 1-amino-2-propanol, N-gluconyl 2-amino-1-propanol, N-gluconyl 2-amino-2-methylpropanol, N-(2-mercaptopropyl)lactamide, edible salts thereof and edible esters thereof.
摘要翻译：第一方面的本发明涉及使用选自式（I）或式（II）所示的物质的组中的调味物质的食品，饮料，制药，烟草制品和口腔护理产品中的风味调节剂，食用盐和它们的食用酯：已经发现，这些物质能够赋予它们所掺入的产品中高度理想的味道特性。此外，所述风味调节物质能够调节和补充其它味道赋予的感官影响，物质因此，本发明的物质有利地应用于风味组合物，食品，药物，烟草制品和口腔护理产品中。根据本发明的风味调节物质的典型实例包括2-羟基-N-（2-羟基-2-甲基丙基） - 丙酰胺，N-乳酰基-1-氨基-2-丙醇，N-乳酰基2-氨基-1- 丙醇，N-乳酰基2-氨基-2-甲基丙醇，N-葡萄糖酸1-氨基-2-甲基-2-丙醇，N-葡萄糖基1-氨基-2-丙醇，N-葡萄糖基-2-氨基-1-丙醇， N-葡萄糖基2-氨基-2-甲基丙醇，N-（2-巯基丙基）乳酰胺，其食用盐和其食用酯。

4. 发明授权

US08815321B2 Geranylamine derivatives as flavouring agents 有权
标题翻译：香叶基胺衍生物作为调味剂
公开(公告)号：US08815321B2
公开(公告)日：2014-08-26
申请号：US13202194
申请日：2010-02-16
申请人： Abdelmajid Kaouas , Harry Renes , Cornelis Winkel
发明人： Abdelmajid Kaouas , Harry Renes , Cornelis Winkel
IPC分类号： A23L1/226 , A23L2/56 , C07C235/06
CPC分类号： A23L1/226 , A23L2/56 , A23L27/20 , A23L27/202 , C07C235/06
摘要： Compounds of the formula (I) A is OH or a carbonyl group, n is 0 or 1, R is an alkyl radical having from 1 to 4 carbon atoms, in particular methyl, ethyl, n-propyl, iso-propyl, n-butyl or t-butyl; or a residue of a hydroxy carboxylic acid, in particular the residue —CH(OH)COOH, —CH(OH)CH2COOH, —CH2CH(OH)COOH or —CH(OH)CH(OH)COOH; and R′ is independently selected from H or OH.
摘要翻译：式（I）的化合物是OH或羰基，n为0或1，R为具有1至4个碳原子的烷基，特别是甲基，乙基，正丙基，异丙基，丁基或叔丁基; 或羟基羧酸的残基，特别是残基-CH（OH）COOH，-CH（OH）CH 2 COOH，-CH 2 CH（OH）COOH或-CH（OH）CH（OH）COOH; 和R'独立地选自H或OH。

5. 发明申请

US20120015089A1 Geranylamine Derivatives As Flavouring Agents 有权
标题翻译：香叶基胺衍生物作为调味剂
公开(公告)号：US20120015089A1
公开(公告)日：2012-01-19
申请号：US13202194
申请日：2010-02-16
申请人： Abdelmajid Kaouas , Harry Renes , Cornelis Winkel
发明人： Abdelmajid Kaouas , Harry Renes , Cornelis Winkel
IPC分类号： A23L1/22 , C07C233/05
CPC分类号： A23L1/226 , A23L2/56 , A23L27/20 , A23L27/202 , C07C235/06
摘要： Compounds of the formula (I) A is OH or a carbonyl group, n is 0 or 1, R is an alkyl radical having from 1 to 4 carbon atoms, in particular methyl, ethyl, n-propyl, iso-propyl, n-butyl or t-butyl; or a residue of a hydroxy carboxylic acid, in particular the residue —CH(OH)COOH, —CH(OH)CH2COOH, —CH2CH(OH)COOH or —CH(OH)CH(OH)COOH; and R′ is independently selected from H or OH.
摘要翻译：式（I）的化合物是OH或羰基，n为0或1，R为具有1至4个碳原子的烷基，特别是甲基，乙基，正丙基，异丙基，丁基或叔丁基; 或羟基羧酸的残基，特别是残基-CH（OH）COOH，-CH（OH）CH 2 COOH，-CH 2 CH（OH）COOH或-CH（OH）CH（OH）COOH; 和R'独立地选自H或OH。

6. 发明授权

US08816102B2 Compounds 有权
标题翻译：化合物
公开(公告)号：US08816102B2
公开(公告)日：2014-08-26
申请号：US13378257
申请日：2010-06-24
申请人： Abdelmajid Kaouas , Harry Renes , Alexander P. Tondeur , Cornelis Winkel
发明人： Abdelmajid Kaouas , Harry Renes , Alexander P. Tondeur , Cornelis Winkel
IPC分类号： C07D317/44 , A24B15/30 , A24B15/36 , A23L1/226 , C07D317/60 , C07C235/34 , C07C235/78
CPC分类号： A23L1/22671 , A23L27/204 , A23L27/2052 , C07C235/34 , C07C235/78 , C07D317/60
摘要： A method of modulating the flavor of an orally-receivable product, such as a foodstuff, beverage, dentifrice or medicine, comprising the addition thereto of a flavor-modulating proportion of at least one compound of the formula I in which X is selected from CHOH, C═O, CH2—CO and CH═C(OH), Y is selected from C1-C7 linear and branched alkyl and CH2CH2OH, Z is selected from CH3 and a moiety of the formula II in which the wavy bond represents bond linking Z to X and R1 and R2 are selected from the possibilities (i) both hydrogen; (ii) independently OH and OCH3; and (iii) R1 and R2 together with their bonds to the phenyl ring form a ring of the formula —O—CH2—O—; such that, when Z is CH3, X is C═O and Y is CH2CH2OH.
摘要翻译：一种调节口服应用产品如食品，饮料，洁齿剂或药物的风味的方法，包括向其中加入风味调节比例的至少一种式I化合物，其中X选自CHOH ，C = O，CH 2 -CO和CH = C（OH），Y选自C 1 -C 7直链和支链烷基和CH 2 CH 2 OH，Z选自CH 3和式II的部分，其中波状键表示键连接 Z至X和R1和R2选自以下可能性（i）氢; （ii）独立地是OH和OCH 3; 和（iii）R1和R2以及它们与苯环的键形成式-O-CH 2 -O-的环; 使得当Z为CH 3时，X为C = O且Y为CH 2 CH 2 OH。

7. 发明授权

US08470384B2 Oxalamide derivative as umami flavouring agent 有权
标题翻译：草酰胺衍生物作为鲜味调味剂
公开(公告)号：US08470384B2
公开(公告)日：2013-06-25
申请号：US13576572
申请日：2011-02-03
申请人： Abdelmajid Kaouas , Cornelis Winkel
发明人： Abdelmajid Kaouas , Cornelis Winkel
IPC分类号： A23L1/226 , C07D213/56
CPC分类号： C07D213/40 , A23L27/2054
摘要： The compound of the formula (1) is novel and is useful in conferring umami taste on consumable compositions, such as foodstuffs and beverages.
摘要翻译：式（1）的化合物是新颖的，并且可用于赋予消费组合物如食品和饮料上的鲜味。

8. 发明申请

US20120093742A1 Compounds 有权
标题翻译：化合物
公开(公告)号：US20120093742A1
公开(公告)日：2012-04-19
申请号：US13378257
申请日：2010-06-24
申请人： Abdelmajid Kaouas , Harry Renes , Alexander P. Tondeur , Cornelis Winkel
发明人： Abdelmajid Kaouas , Harry Renes , Alexander P. Tondeur , Cornelis Winkel
IPC分类号： A61K8/44 , C07D317/60 , A23L1/226 , C07C233/11 , A61Q11/00 , A61K8/49 , C07C233/22 , C07C233/18
CPC分类号： A23L1/22671 , A23L27/204 , A23L27/2052 , C07C235/34 , C07C235/78 , C07D317/60
摘要： A method of modulating the flavour of an orally-receivable product, such as a foodstuff, beverage, dentifrice or medicine, comprising the addition thereto of a flavour-modulating proportion of at least one compound of the formula I in which X is selected from CHOH, C═O, CH2—CO and CH═C(OH), Y is selected from C1-C7 linear and branched alkyl and CH2CH2OH, Z is selected from CH3 and a moiety of the formula II in which the wavy bond represents bond linking Z to X and R1 and R2 are selected from the possibilities (i) both hydrogen; (ii) independently OH and OCH3; and (iii) R1 and R2 together with their bonds to the phenyl ring form a ring of the formula —O—CH2—O—; such that, when Z is CH3, X is C═O and Y is CH2CH2OH.
摘要翻译：一种调节口服应用产品如食品，饮料，洁齿剂或药物的风味的方法，包括向其中加入风味调节比例的至少一种式I化合物，其中X选自CHOH ，C = O，CH 2 -CO和CH = C（OH），Y选自C 1 -C 7直链和支链烷基和CH 2 CH 2 OH，Z选自CH 3和式II的部分，其中波状键表示键连接 Z至X和R1和R2选自以下可能性（i）氢; （ii）独立地是OH和OCH 3; 和（iii）R1和R2以及它们与苯环的键形成式-O-CH 2 -O-的环; 使得当Z为CH 3时，X为C = O且Y为CH 2 CH 2 OH。

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