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1. 发明授权

US10639028B2 Endoscopic suture loop anchors and methods 有权
公开(公告)号：US10639028B2
公开(公告)日：2020-05-05
申请号：US15336024
申请日：2016-10-27
申请人： Apollo Endosurgery, Inc.
发明人： John Mims , Charles Dean , Nicole Pinto , Mitchell Gilkey , Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B17/04 , A61B17/062 , A61B17/06 , A61B17/29 , A61F5/00 , A61B17/00
CPC分类号： A61B17/0469 , A61B17/0482 , A61B17/0485 , A61B17/0487 , A61B17/0625 , A61B17/06061 , A61B17/06109 , A61B17/06166 , A61B17/29 , A61F5/0089 , A61B2017/00004 , A61B2017/00296 , A61B2017/00818 , A61B2017/0417 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/06176
摘要： A suture needle system includes a first needle and at least one second needle. Each of the first and second needles preferably has a common needle body construct. The first needle includes an elongate suture having a length sufficient to extend at least the length of an instrument channel of an endoscope. The second needle includes an opening formed by a loop of suture at which the second needle can be advanced over the elongate suture. In use, the first needle is secured to a first tissue location using an endoscopic suturing system. A second needle is advanced at its opening over the elongate suture and secured to a second tissue location. Additional second needles may be advanced over the elongate suture to respective tissue locations. The elongate suture is pulled taut, drawing the second needles into proximity, and secured.

2. 发明申请

US20190008669A1 ANCHORED NON-PIERCING DUODENAL SLEEVE AND DELIVERY SYSTEMS 审中-公开
公开(公告)号：US20190008669A1
公开(公告)日：2019-01-10
申请号：US16126326
申请日：2018-09-10
申请人： Apollo Endosurgery, Inc.
发明人： Mitchell H. Babkes , Zachary P. Dominguez , Christopher S. Mudd
IPC分类号： A61F5/00
摘要： An intragastric implant for obesity treatment is disclosed. The device delays digestion by providing a duodenal sleeve, and may also slows gastric emptying by limiting flow through the pyloric sphincter. The implant includes an elongated axially-compressible duodenal sleeve having a non-tissue-piercing anchor on a proximal end sized to lodge within the duodenal bulb. The anchor may have oppositely-directed anchoring flanges to resists migration in both directions. The sleeve may also have barbed ribs to resist proximal movement back up into the stomach. A method of implant includes collapsing/compressing the device and transorally advancing it through the esophagus to be deployed within the duodenum. A dissolvable jacket may constrain the implant for delivery and naturally dissolve upon implant. Removal of the implant may occur in the reverse.

3. 发明授权

US10111771B2 Bariatric device and method for weight loss 有权
公开(公告)号：US10111771B2
公开(公告)日：2018-10-30
申请号：US14792936
申请日：2015-07-07
申请人： Apollo Endosurgery, Inc.
发明人： Janel Birk , Daniel Dongelmans
IPC分类号： A61F5/00 , A61F2/04
摘要： A bariatric device 10 for use in inducing weight loss, comprising a cardiac element 12, a pyloric element 26, and a connecting element 25 between the two other elements, wherein the connecting element 25 provides structure between the cardiac 12 and pyloric 26 elements, keeping them largely in place and at least intermittently touching and applying pressure to the stomach's cardiac, adjacent fundic and pyloric regions, respectively, which produces a satiety signal to the user, giving the recipient a feeling of fullness and reducing his or her hunger feelings. Alternatively, the cardiac 12 and pyloric 26 elements may be symmetrical, so that the device can orient itself either way in the stomach and still achieve the weight loss function. Alternatively, the cardiac 12 and/or pyloric 26 elements may have a restriction element to slow gastric filling or emptying, to produce a satiety signal. In any of the embodiments, the bariatric device may be made from multiple sizes or adjustable, either manually, automatically or remotely, to optimally size and/or position the device to produce the desired satiety signals and weight loss.

4. 发明申请

US20150272761A1 Intragastric Balloon for Treating Obesity 有权
标题翻译：用于治疗肥胖的胃内气囊
公开(公告)号：US20150272761A1
公开(公告)日：2015-10-01
申请号：US14433752
申请日：2013-10-03
申请人： APOLLO ENDOSURGERY, INC.
发明人： Justin J. Schwab , Zachary P. Dominguez , Joseph S. Raven , Mitchell H. Babkes , Christopher S. Mudd , Tiago Bertolote
IPC分类号： A61F5/00
CPC分类号： A61F5/003 , A61F5/0033 , A61F5/0036
摘要： A transorally implanted intragastric balloon or treating obesity and for weight control including a variable size balloon with one or interconnected regions acting to exert a pressure on the stomach, to provide a stomach volume occupying effect, and/or to anchor the balloon within the stomach.
摘要翻译：经胃内植入的胃内球囊或治疗肥胖症并且用于体重控制，包括具有一个或互连的区域的可变大小的球囊，其作用于对胃施加压力，以提供胃体积占据效果，和/或将囊固定在胃内。

5. 发明申请

US20150190166A1 Methods and Systems for Submucosal Implantation of a Device for Diagnosis and Treatment of a Body 审中-公开
标题翻译：用于身体诊断和治疗的装置的粘膜下植入的方法和系统
公开(公告)号：US20150190166A1
公开(公告)日：2015-07-09
申请号：US14590390
申请日：2015-01-06
申请人： Apollo Endosurgery, Inc.
发明人： Vladimir Mitelberg , Donald K. Jones , Brett E. Naglreiter , Dennis L. McWilliams
IPC分类号： A61B17/32 , A61N1/372 , A61B17/068 , A61N1/36 , A61B17/34
CPC分类号： A61B17/320016 , A61B17/068 , A61B17/3468 , A61B17/3478 , A61B17/3496 , A61B2017/00269 , A61B2017/00818 , A61B2017/2937 , A61B2017/320048 , A61B2017/320056 , A61F2002/30668 , A61F2250/0001 , A61M25/0084 , A61M25/10 , A61N1/0509 , A61N1/36007 , A61N1/37217
摘要： Instruments, systems and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument and a submucosal tunneling instrument, a submucosal dissection instrument, and a mucosal resection device. Systems include a combination of one or more of such instruments with or without injectable agents. Embodiments of various methods for performing the procedures are also provided. In accordance with one aspect there is provided a submucosal implant device for diagnosing and treating disorders of the body. The submucosal implant device may take the form of a gastric stimulator in which signals are supplied to the muscular wall of a mammal to treat motility disorders. In accordance with yet another aspect there is provided a method for performing a submucosal medical procedure to deploy a submucosal implant device in the digestive tract of a mammal.
摘要翻译：提供了仪器，系统和方法，用于使用内窥镜检查在消化道的期望区域中进行粘膜下的医学过程。仪器包括安全通道针注射器械和粘膜下隧道仪器，粘膜下剥离仪器和粘膜切除装置。系统包括具有或不具有可注射剂的一种或多种这样的仪器的组合。还提供了用于执行该过程的各种方法的实施例。根据一个方面，提供了一种用于诊断和治疗身体疾病的粘膜下植入装置。粘膜下植入装置可以采取胃刺激剂的形式，其中向哺乳动物的肌肉壁提供信号以治疗运动障碍。根据另一方面，提供了一种用于执行粘膜下部医疗程序以在哺乳动物的消化道中部署粘膜下植入装置的方法。

6. 发明申请

US20150150702A1 Releasably-Securable One-Piece Adjustable Gastric Band 审中-公开
标题翻译：可拆卸式一体式可调节胃带
公开(公告)号：US20150150702A1
公开(公告)日：2015-06-04
申请号：US14557778
申请日：2014-12-02
申请人： Apollo Endosurgery, Inc.
发明人： Janel A. Birk
IPC分类号： A61F5/00
CPC分类号： A61F5/0066 , A61B17/1327 , A61B17/135 , A61F5/003 , A61F5/0056
摘要： A releasably-securable gastric band having a tail end and a head end for receiving the tail end is disclosed. The gastric band also includes a releasable locking structure means that releasably secures the head and tail ends together. The tail end may include a tooth and the head end may include a notch for engaging the tooth. Upon insertion of the tail end into the head end, the tooth mates with the notch and releasably locks the tail end in the head end. The releasably-securable gastric band includes a release tab. When force is applied to the release tab in a direction perpendicular to a central axis of the gastric band, the tooth is disengaged from the notch to allow the gastric band to be released.
摘要翻译：公开了具有尾端和用于接收尾端的头端的可释放地固定的胃带。胃带还包括可释放的锁定结构装置，其将头端和尾端可释放地固定在一起。尾端可以包括齿，并且头端可以包括用于接合牙齿的凹口。当将尾端插入头端时，牙齿与凹口配合并将尾端可释放地锁定在头端。可释放地安全的胃带包括释放片。当沿垂直于胃束带的中心轴线的方向将力施加到释放片时，牙齿与凹口脱离接合以允许胃带释放。

7. 发明申请

US20150126807A1 Dome and Screw Valves for Remotely Adjustable Gastric Banding Systems 审中-公开
标题翻译：用于远程可调胃带系统的圆顶和螺旋阀
公开(公告)号：US20150126807A1
公开(公告)日：2015-05-07
申请号：US14556754
申请日：2014-12-01
申请人： Apollo Endosurgery, Inc.
发明人： Janel A. Birk , Sean Snow , Robert E. Hoyt, JR.
IPC分类号： A61F5/00
CPC分类号： A61F5/0059 , A61F5/003 , A61F5/0056 , A61F5/0066 , Y10T137/7374 , Y10T137/87716
摘要： An implantable device controls the movement of fluid to an inflatable portion of a gastric band. The implantable device includes a body. The body has an inlet, an outlet and a valve seat positioned between the inlet and the outlet. The body defines a fluid passage from the inlet to the outlet. The implantable device also includes a diaphragm. The diaphragm has one or more edges coupled to the body. The diaphragm is made of an elastomeric material and capable of being moved between a closed position that blocks the valve seat and does not allow the fluid to move from the inlet to the outlet and an open position that does not block the valve seat and allows the fluid to move from the inlet to the outlet.
摘要翻译：可植入装置控制流体到胃带的可充气部分的运动。可植入装置包括主体。本体具有入口，出口和位于入口和出口之间的阀座。主体限定了从入口到出口的流体通道。可植入装置还包括隔膜。隔膜具有连接到身体的一个或多个边缘。隔膜由弹性体材料制成，并且能够在阻塞阀座的关闭位置之间移动并且不允许流体从入口移动到出口以及不阻塞阀座的打开位置，并允许流体从入口移动到出口。

8. 发明申请

US20130096581A1 Method of endoscopic suturing 审中-公开
标题翻译：内窥镜缝合方法
公开(公告)号：US20130096581A1
公开(公告)日：2013-04-18
申请号：US13650507
申请日：2012-10-12
申请人： Apollo Endosurgery, Inc.
发明人： J. Landon Gilkey , Brett E. Naglreiter , Peter K. Kratsch , Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61B17/04
摘要： An endoscopic suturing system and method are disclosed as are devices for use with the system and method such as a suture dispenser, a cinch device, and a tissue grasper. In one embodiment the suturing system includes a cap assembly arranged at the distal end portion of an endoscope or guide member, with the cap assembly including a rotatable needle holder. The needle holder is actuated through a transmission element extending outside the endoscope or guide member. A needle capture device may be inserted through a channel of the endoscope or guide member in order to capture a needle held in the needle holder when the needle holder is rotated so that the needle punctures tissue.
摘要翻译：公开了内窥镜缝合系统和方法，用于与系统和方法一起使用的装置，例如缝合分配器，束带装置和组织抓紧器。在一个实施例中，缝合系统包括布置在内窥镜或引导构件的远端部分处的帽组件，帽组件包括可旋转的针保持器。针保持器通过延伸到内窥镜或引导构件外部的传动元件致动。可以通过内窥镜或引导构件的通道插入针捕获装置，以便当针保持器旋转时捕获保持在针保持器中的针，使得针刺穿组织。

9. 发明授权

US11534160B2 Endoscopic needle assembly 有权
公开(公告)号：US11534160B2
公开(公告)日：2022-12-27
申请号：US14924087
申请日：2015-10-27
申请人： Apollo Endosurgery, Inc.
发明人： Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B17/062 , A61B1/00 , A61B1/018 , A61B1/04 , A61B17/04 , A61B17/06 , A61B17/068 , A61B50/13 , A61B17/00 , A61B17/064 , A61B17/29
摘要： A needle and suture assembly is provided for use with an endoscopic suturing device with a needle holder arm. The needle assembly includes a needle tip and a needle body. The needle tip has a sharp end, a capture groove, a tab groove and a plug portion positioned between the capture groove and the tab groove. The needle body has first and second ends, tip tabs, retainers for removably retaining the needle body relative to the needle holder arm, and a suture opening. The needle tip is fixed relative to the needle body by plastic deformation of the tip tabs into the tab groove. A suture extends into the suture opening of the needle body and is fixed therein.

10. 发明授权

US10932935B2 Method of implanting an intragastric balloon 有权
公开(公告)号：US10932935B2
公开(公告)日：2021-03-02
申请号：US16030098
申请日：2018-07-09
申请人： Apollo Endosurgery, Inc.
发明人： Owen Shawn Sobelman , Janel A. Birk
IPC分类号： A61F5/00 , A61M39/26 , A61M29/02 , A61M39/00
摘要： A method includes providing an inflatable implant formed of a flexible polymer material suitable for residence in the body. The implant includes a slit valve provided in its wall. The slit valve includes an elastomeric valve body with an open internal chamber being in fluid communication with a proximal opening of the valve, a concave section at its distal end, and a normally closed slit in a solid portion of the valve body connecting the concave section and the distal end of the valve body. An inflation tube having an injection tip with a distal end and an insertion stop is provided. The injection tip is inserted into the internal chamber of the slit valve until the insertion stop positively engages the proximal opening. Then, the implant with the inflation tube is delivered to a body cavity. Once delivered, fluid is introduced through the inflation tube and into the implant.

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