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    • 3. 发明授权
    • Methods, systems and devices for improving ventilation in a lung area
    • 用于改善肺部通气的方法,系统和装置
    • US07588033B2
    • 2009-09-15
    • US10870849
    • 2004-06-17
    • Anthony David Wondka
    • Anthony David Wondka
    • A61M15/00
    • A61M16/10A61M16/0009A61M16/0012A61M16/04A61M16/0404A61M16/042A61M16/0434A61M16/0445A61M16/0459A61M16/0465A61M16/0486A61M16/0672A61M2016/0021A61M2016/103A61M2205/8225A61M2209/06A61M2230/432
    • Methods, systems and devices are described for new modes of ventilation in which specific lung areas are ventilated with an indwelling trans-tracheobronchial catheter for the purpose of improving ventilation and reducing hyperinflation in that specific lung area, and for redistributing inspired air to other healthier lung areas, for treating respiratory disorders such as COPD, ARDS, SARS, CF, and TB. Trans-Tracheobronchial Segmental Ventilation (TTSV) is performed on either a naturally breathing or a mechanical ventilated patient by placing a uniquely configured indwelling catheter into a bronchus of a poorly ventilated specific lung area and providing direct ventilation to that area. The catheter can be left in place for extended periods without clinician attendance or vigilance. Ventilation includes delivery of respiratory gases, therapeutic gases or agents and evacuation of stagnant gases, mixed gases or waste fluids. Typically the catheter's distal tip is anchored without occluding the bronchus but optionally may intermittently or continuously occlude the bronchus. TTSV is optionally performed by insufflation only of the area, or by application of vacuum to the area, can include elevating or reducing the pressure in the targeted area to facilitate stagnant gas removal, or can include blocking the area to divert inspired gas to better functioning areas.
    • 描述了新的通气模式,其中特定的肺部区域通过留置的经气管支气管导管通气,目的是改善通气并减少特定肺部的恶性通气,并将启发的空气重新分配到其他更健康的肺部 区域,用于治疗呼吸系统疾病如COPD,ARDS,SARS,CF和TB。 通过将气管支气管节段通气(TTSV)通过将独特配置的留置导管置于通气不良的特定肺部区域的支气管中,并对该区域进行直接通气,在自然呼吸或机械通气患者进行。 导管可以长时间留在原位,无需临床医生出勤或警惕。 通风包括呼吸气体,治疗气体或药剂的输送以及停滞的气体,混合气体或废液的排放。 通常,导管的远侧末端被锚定而不阻塞支气管,但是可任选地间断地或连续地闭塞支气管。 TTSV任选地仅通过吹扫区域进行,或者通过向该区域施加真空,可以包括升高或降低目标区域中的压力以促进停滞的气体去除,或者可以包括阻挡该区域以将启发的气体转移到更好的功能 地区
    • 9. 发明申请
    • Methods, Systems and Devices for Desufflating a Lung Area
    • 用于解除肺部区域的方法,系统和装置
    • US20120041361A1
    • 2012-02-16
    • US13279281
    • 2011-10-23
    • Anthony David Wondka
    • Anthony David Wondka
    • A61M37/00A61M25/00
    • A61M16/0463A61M16/00A61M16/04A61M16/0434A61M16/0486A61M2016/0027A61M2230/432
    • Methods, systems and devices are described for temporarily or permanently evacuating stagnating air from a diseased lung area, typically for the purpose of treating COPD. Evacuation is accomplished by displacing the stagnant CO2-rich air with a readily diffusible gas using a trans-luminal indwelling catheter specially configured to remain anchored in the targeted area for long term treatment without supervision. Elevated positive gas pressure in the targeted area is then regulated via the catheter and a control unit to force under positive pressure effusion of the diffusible gas out of the area into neighboring areas while inhibiting infusion of other gases thus effecting a gradual gas volume decrease and deflation of the targeted area, thereby reducing volume of ineffective areas, increasing tidal volume of better areas, and improving lung mechanics.
    • 描述了方法,系统和装置,用于临时或永久地排出来自患病肺部区域的停滞空气,通常用于治疗COPD。 疏散是通过使用特别配置为保持锚定在目标区域中的经腔内留置导管用容易扩散的气体置换停滞的富含CO 2的空气来实现的,以进行长期治疗而无需监督。 然后通过导管和控制单元通过导管和控制单元调节正压气体压力,以便将可扩散气体的正压力渗出到区域外进入邻近区域,同时抑制其它气体的输注,从而实现逐渐的气体体积减小和通气 的目标区域,从而减少无效区域的数量,增加潮气量,改善肺部力量。
    • 10. 发明授权
    • Methods, systems and devices for desufflating a lung area
    • 用于去除肺部区域的方法,系统和装置
    • US08082921B2
    • 2011-12-27
    • US10831573
    • 2004-04-24
    • Anthony David Wondka
    • Anthony David Wondka
    • A61M11/00
    • A61M16/0463A61M16/00A61M16/04A61M16/0434A61M16/0486A61M2016/0027A61M2230/432
    • Methods, systems and devices are described for temporarily or permanently evacuating stagnating air from a diseased lung area, typically for the purpose of treating COPD. Evacuation is accomplished by displacing the stagnant CO2-rich air with a readily diffusible gas using a transluminal indwelling catheter specially configured to remain anchored in the targeted area for long term treatment without supervision. Appropriate elevated positive gas pressure in the targeted area is then regulated via the catheter and a pneumatic control unit to force under positive pressure effusion of the diffusible gas out of the area into neighboring areas while inhibiting infusion of other gases thus effecting a gradual gas volume decrease and deflation of the targeted area.
    • 描述了方法,系统和装置,用于临时或永久地排出来自患病肺部区域的停滞空气,通常用于治疗COPD。 疏散是通过使用专门配置为保持锚定在目标区域中的长期治疗而不进行监督的经腔留置导管用容易扩散的气体置换停滞的富CO 2空气来实现的。 然后通过导管和气动控制单元调节目标区域中适当升高的正气压,并将气体控制单元在正向压力下将可扩散气体排出区域进入邻近区域,同时抑制其他气体的输入,从而实现逐渐的气体体积减小 和通货紧缩的目标地区。