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1. 发明申请

US20030109868A1 Medical instrument positioning tool and method 审中-公开
公开(公告)号：US20030109868A1
公开(公告)日：2003-06-12
申请号：US10301975
申请日：2002-11-21
申请人： AFX, INC.
发明人： Sing Fatt Chin , Dany Berube , Dinesh I. Mody , Nancy Norris
IPC分类号： A61B018/14
CPC分类号： A61B18/1492 , A61B18/02 , A61B18/18 , A61B18/1815 , A61B2017/00243 , A61B2018/00375 , A61B2018/00839 , A61B2018/0212 , A61B2018/1407 , A61B2018/1497
摘要： A system and method for positioning a medical instrument at a desired biological target tissue site is provided. The system includes an elongated sheath having a deflectable distal end configured to deflect or otherwise position at least a portion of a medical instrument during a surgical procedure allowing for the placement of the deflected portion adjacent or proximate to a predetermined target tissue surface. The positioning system may be incorporated into the medical instrument. The medical instrument may be an ablation system.

2. 发明申请

US20020111613A1 Monopole tip for ablation catheter and methods for using same 失效
标题翻译：用于消融导管的单极尖端及其使用方法
公开(公告)号：US20020111613A1
公开(公告)日：2002-08-15
申请号：US09904156
申请日：2001-07-31
申请人： AFx, Inc.
发明人： Dany Berube
IPC分类号： A61B018/04
CPC分类号： A61B18/1492
摘要： An ablation catheter apparatus with a monopole antenna that is arranged to provide a relatively uniform electric field and a method for using such an ablation catheter apparatus are disclosed. According to one aspect of the present invention, an ablation catheter includes an elongated flexible tubular member that is adapted to be inserted into the body of a patient, and a transmission line that is disposed within the tubular member. The transmission line has a distal end and a proximal end which is arranged to be connected to an electromagnetic energy source. The catheter also includes a monopole antenna with tip section and a body section that includes a distal end and a proximal end. The tip section and the body section are arranged to produce a relatively uniform electric field around the monopole antenna which is sufficiently strong to cause tissue ablation. The proximal end of the body section of the monopole antenna is arranged to be electrically coupled to the transmission line.
摘要翻译：公开了一种具有设置成提供相对均匀电场的单极天线的消融导管装置和使用这种消融导管装置的方法。根据本发明的一个方面，消融导管包括适于插入患者体内的细长柔性管状构件和设置在管状构件内的传输线。传输线具有远端和近端，其被布置成连接到电磁能源。导管还包括具有尖端部分的单极天线和包括远端和近端的主体部分。尖端部分和主体部分布置成在单极天线周围产生相当均匀的电场，该电场足够强以引起组织消融。单极天线的主体部分的近端被布置成电耦合到传输线。

3. 发明申请

US20040106937A1 Clamp accessory and method for an ablation instrument 审中-公开
标题翻译：夹具附件和消融仪器的方法
公开(公告)号：US20040106937A1
公开(公告)日：2004-06-03
申请号：US10602372
申请日：2003-06-23
申请人： AFx, Inc.
发明人： Dany Berube , Ketan Shroff , Pierre-Antoine Chapelon
IPC分类号： A61B017/08
CPC分类号： A61B17/122 , A61B18/14 , A61B2017/00026 , A61B2017/2944
摘要： An apparatus and method is provided as an accessory to an ablation device or instrument. The accessory includes a first and second jaw members adapted to work with an existing ablation device during ablation of biological tissue. The first jaw member includes a partial lumen adapted to accept and hold an ablation device therein. The accessory further includes a clamping means operably attached to the jaw members to facilitate placement and retention of target tissue therebetween. The accessory may incorporate a transmurality assessment system to determined whether the ablation is complete. The transmurality system may actively or passively obtain tissue characteristics indicating transmurality. These transmurality systems may includes two or more electrodes which each measure at least one of conduction time, conduction distance, conduction velocity, phase angle, and impedance through at least a portion of the targeted tissue to determine the transmurality of the ablation lesion.
摘要翻译：作为消融装置或器械的附件提供了一种装置和方法。附件包括适于在消融生物组织期间与现有消融装置一起工作的第一和第二钳口构件。第一钳口构件包括适于在其中接受和保持消融装置的部分内腔。附件还包括可操作地附接到钳口构件的夹紧装置，以便于在其间放置和保持目标组织。附件可以包括透视度评估系统以确定消融是否完成。透壁系统可以主动地或被动地获得指示透壁性的组织特征。这些透壁系统可以包括两个或更多个电极，每个电极通过目标组织的至少一部分测量导电时间，导电距离，传导速度，相位角和阻抗中的至少一个，以确定消融损伤的透壁性。

4. 发明申请

US20030069575A1 Tissue ablation system with a sliding ablating device and method 审中-公开
标题翻译：具有滑动消融装置和方法的组织消融系统
公开(公告)号：US20030069575A1
公开(公告)日：2003-04-10
申请号：US10177840
申请日：2002-06-21
申请人： AFX, INC.
发明人： Sing Fatt Chin , Berube Dany , Dinesh I. Mody , Nancy Norris
IPC分类号： A61B018/14
CPC分类号： A61B18/1492 , A61B18/02 , A61B18/18 , A61B18/1815 , A61B2017/00243 , A61B2018/00375 , A61B2018/00839 , A61B2018/0212 , A61B2018/1407 , A61B2018/1497
摘要： A system and method for ablating a selected portion of a contact surface of biological tissue is provided. The system includes an elongated ablation sheath having a preformed shape adapted to substantially conform a predetermined surface thereof with the contact surface of the tissue. The ablation sheath defines an ablation lumen sized to slideably receive an elongated ablative device longitudinally therethrough. The ablative device includes a flexible ablation element selectively generating an ablative field sufficiently strong to cause tissue ablation. Advancement of the ablation element slideably through the ablation lumen of the ablation sheath selectively places the ablation element along the ablation path for guide ablation on the contact surface when the predetermined surface is in strategic contact therewith. The ablation lumen and the ablative device cooperate to position the ablation element proximate to the ablation sheath predetermined surface for selective ablation of the selected portion within the ablative field.
摘要翻译：提供了用于烧蚀生物组织的接触表面的选定部分的系统和方法。该系统包括具有适于基本上使其与组织的接触表面的预定表面一致的预成型形状的细长消融护套。消融套限定了消融腔，其大小可纵向滑动地容纳细长的消融装置。烧蚀装置包括柔性消融元件，其选择性地产生足够强以引起组织消融的烧蚀场。当消融元件可滑动地穿过消融鞘的消融腔时，推进消融元件选择性地将消融元件沿着烧蚀路径放置，以在预定表面与其接触时与接触表面进行引导消融。消融腔和消融装置配合以将消融元件靠近消融鞘预定表面定位，以在烧蚀区内选择性地烧蚀所选择的部分。

5. 发明申请

US20170325298A1 LIGHT BRIGHTNESS AND COLOR TEMPERATURE CONTROL UNIT 有权
公开(公告)号：US20170325298A1
公开(公告)日：2017-11-09
申请号：US15587453
申请日：2017-05-05
申请人： AFX Inc.
发明人： Gregory WEISS , Bill Solomon
IPC分类号： H05B33/08
CPC分类号： H05B33/083 , H05B33/0854 , H05B33/0863 , H05B33/0872
摘要： A light control unit that includes a housing sized and shaped as a standard electrical dimmer switch that can reside in an a standard electrical Handy Box and at least one integrated circuit that comprises a brightness dimming control adapted to reduce and increase brightness of one or more light sources, for example a series of light sources, electronically connected to the at least one integrated circuit and a correlated color temperature (CCT) control adapted to change color temperature of light emitted from the one or more light sources.

6. 发明申请

US20030163128A1 Tissue ablation system with a sliding ablating device and method 审中-公开
标题翻译：具有滑动消融装置和方法的组织消融系统
公开(公告)号：US20030163128A1
公开(公告)日：2003-08-28
申请号：US10348256
申请日：2003-01-21
申请人： AFX, INC.
发明人： Nitin A. Patil , Manoj Akkad , Sing Fatt Chin , Dany Berube , Dinesh I. Mody , Nancy Norris
IPC分类号： A61B018/18
CPC分类号： A61B18/24 , A61B5/0538 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B2017/00243 , A61B2018/00375 , A61B2018/00577 , A61B2018/00839 , A61B2018/1407
摘要： A system and method for ablating a selected portion of a contact surface of biological tissue is provided. The system includes an elongated ablation sheath having a preformed shape adapted to substantially conform a predetermined surface thereof with the contact surface of the tissue. The elongated ablation sheath includes a non-permeable portion. The ablation sheath defines an ablation lumen sized to slideably receive an elongated ablative device longitudinally therethrough. The ablative device includes a flexible ablation element selectively generating an ablative field sufficiently strong to cause tissue ablation. Advancement of the ablation element slideably through the ablation lumen of the ablation sheath selectively places the ablation element along the ablation path for guide ablation on the contact surface when the predetermined surface is in strategic contact therewith. The ablation lumen and the ablative device cooperate to position the ablation element proximate to the ablation sheath predetermined surface for selective ablation of the selected portion within the ablative field.
摘要翻译：提供了用于烧蚀生物组织的接触表面的选定部分的系统和方法。该系统包括具有适于基本上使其与组织的接触表面的预定表面一致的预成型形状的细长消融护套。细长消融鞘包括不可渗透部分。消融套限定了消融腔，其大小可纵向滑动地容纳细长的消融装置。烧蚀装置包括柔性消融元件，其选择性地产生足够强以引起组织消融的烧蚀场。当消融元件可滑动地穿过消融鞘的消融腔时，推进消融元件选择性地将消融元件沿着烧蚀路径放置，以在预定表面与其接触时与接触表面进行引导消融。消融腔和消融装置配合以将消融元件靠近消融鞘预定表面定位，以在烧蚀区内选择性地烧蚀所选择的部分。

7. 发明申请

US20030125720A1 Ablation instrument having a flexible distal portion 失效
标题翻译：消融仪器具有柔性的远端部分
公开(公告)号：US20030125720A1
公开(公告)日：2003-07-03
申请号：US10039872
申请日：2002-01-03
申请人： AFx INC.
发明人： Robert E. Woodard , Hiep Nguyen , Dany Berube
IPC分类号： A61B017/20 , A61B018/18 , A61B017/32
CPC分类号： A61B18/1815 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/1861 , A61B2090/0454
摘要： An ablation instrument having a flexible portion at or near the distal portion of the instrument, is provided. The instrument includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal portion, comprising an ablation device, during an ablation procedure. The instrument further includes a deflectable member which cooperates with the steering system allowing for the proper placement of the ablation device adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.
摘要翻译：提供了一种在仪器的远端部分或其附近具有柔性部分的消融器械。仪器包括细长的管状构件，其具有可转向的远端，构造成在消融过程期间偏转或以其它方式指导和适当地定位包括消融装置的远侧部分的至少一部分。仪器还包括与转向系统配合的可偏转构件，允许消融装置在目标组织表面附近或邻近处适当放置。转向系统可替代地作为导管系统的一部分并入到单独的引导导管中。

8. 发明申请

US20030073988A1 Microwave ablation instrument with insertion probe 失效
标题翻译：带插入式探头的微波消融仪
公开(公告)号：US20030073988A1
公开(公告)日：2003-04-17
申请号：US10159422
申请日：2002-05-29
申请人： AFx INC.
发明人： Dany Berube , Mary Elizabeth Bush
IPC分类号： A61B018/18
CPC分类号： A61B18/18 , A61B18/1815
摘要： A microwave ablation assembly and method including a relatively thin, elongated probe (21) having a proximal access end (22) and an opposite distal penetration end (23) adapted to penetrate into bio-tissue (25). The probe (21) defines an insert passage (26) extending therethrough from the access end (22) to the penetration end (23) thereof. An ablation catheter includes a coaxial transmission line (28) with an antenna device (30) coupled to a distal end of the transmission line (28) for generating an electric field sufficiently strong to cause tissue ablation. The coaxial transmission line (28) includes an inner conductor (31) and an outer conductor (32) separated by a dielectric material medium (33). A proximal end of the transmission line (28) is coupled to a microwave energy source. The antenna device (30) and the transmission line (28) each have a transverse cross-sectional dimension adapted for sliding receipt through the insert passage (26) while the elongated probe (21) is positioned in the bio-tissue (25). Such sliding advancement continues until the antenna device (30) is moved to a position beyond the penetration end (23) and further into direct contact with the bio-tissue (25).
摘要翻译：一种微波消融组件和方法，包括具有近端进入端（22）和适于穿透入生物组织（25）的相对的远端穿透端（23）的相对薄的细长探针（21）。探针（21）限定了从入口端（22）穿过其延伸到其穿透端（23）的插入通道（26）。消融导管包括具有耦合到传输线（28）的远端的天线装置（30）的同轴传输线（28），用于产生足够强的电场以引起组织消融。同轴传输线（28）包括由介电材料介质（33）分开的内部导体（31）和外部导体（32）。传输线（28）的近端耦合到微波能量源。天线装置（30）和传输线（28）各自具有适于在细长探针（21）定位在生物组织（25）中时通过插入通道（26）滑动接收的横截面尺寸。这种滑动推进继续进行，直到天线装置（30）移动到超过穿透端（23）的位置并进一步直接与生物组织（25）接触。

9. 发明申请

US20030220639A1 Apparatus and method for assessing transmuarlity of a tissue ablation 失效
标题翻译：评估组织消融的变异性的装置和方法
公开(公告)号：US20030220639A1
公开(公告)日：2003-11-27
申请号：US10369887
申请日：2003-02-19
申请人： AFX, INC.
发明人： Pierre-Antoine Chapelon , Dany Berube , Hiep Nguyen , Faouzi Kallel
IPC分类号： A61B018/04 , A61B018/18 , A61B005/05
CPC分类号： A61B18/1492 , A61B2017/00026 , A61B2017/00243 , A61B2018/00351 , A61B2018/00702 , A61B2018/00875
摘要： An instrument is provided to assess the transmurality of an ablation lesion from a first surface of a targeted biological tissue to an opposed second surface thereof. The instrument includes at least a first electrode operably attached to an ablation instrument adapted to engage a tissue first surface, and at least a second electrode adapted to engage a tissue second surface, the at least second electrode positioned generally opposed to the at least first electrode. Alternatively, the at least second electrode may be adapted to be placed within a chamber of an organ. These electrodes each measure at least one of conduction time, conduction velocity, phase angle, and impedance through at least a portion of the targeted tissue to determine the transmurality of the ablation lesion.
摘要翻译：提供了一种用于评估消融病变从目标生物组织的第一表面到其相对的第二表面的透壁性的仪器。所述仪器包括至少第一电极，其可操作地附接到适于接合组织第一表面的消融仪器，以及适于接合组织第二表面的至少第二电极，所述至少第二电极与所述至少第一电极大致相对。或者，至少第二电极可以适于放置在器官的腔室内。这些电极各自通过目标组织的至少一部分来测量传导时间，传导速度，相位角和阻抗中的至少一个，以确定消融损伤的透壁性。

10. 发明申请

US20030125730A1 Flexible device for ablation of biological tissue 失效
标题翻译：用于生物组织消融的柔性装置
公开(公告)号：US20030125730A1
公开(公告)日：2003-07-03
申请号：US10039873
申请日：2002-01-03
申请人： AFX INC.
发明人： Dany Berube , Pierre-Antoine Chapelon
IPC分类号： A61B018/04 , A61B018/18
CPC分类号： A61B18/1492 , A61B18/1815
摘要： An ablation system incorporating an enhanced deflectable distal portion, is provided. The system includes an elongated tubular member having a deflectable distal portion adapted to assume a specific predetermined or predefined shape when deployed. The predetermined shape allows for the creation of a desired uniform energy emission pattern with respect to a target tissue, such that energy may be directed toward the target tissue independent of an approach orientation of the ablation system. The energy pattern results in the creation of a desired tissue ablation. The ablation system may further comprise a steering system which aides in directing the distal portion toward a target tissue site. The steering system may alternatively be incorporated into a separate guiding catheter as part of the ablation system.
摘要翻译：提供了包括增强的可偏转远端部分的消融系统。该系统包括细长的管状构件，其具有适于在展开时呈现特定的预定或预定形状的可偏转远端部分。预定形状允许相对于目标组织产生期望的均匀能量发射图案，使得能量可以独立于消融系统的进近取向指向靶组织。能量模式导致产生期望的组织消融。消融系统还可以包括转向系统，其将远端部分引导朝向目标组织部位。作为消融系统的一部分，转向系统可以可选地并入到单独的引导导管中。

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