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1. 发明授权

US07584118B1 Methods and systems for electronic affiliate compensation 有权
标题翻译：电子会员赔偿的方法和系统
公开(公告)号：US07584118B1
公开(公告)日：2009-09-01
申请号：US09888850
申请日：2001-06-25
申请人： Kiran Bellare , Michele Monclova Father , Jean-Christophe Meriaux
发明人： Kiran Bellare , Michele Monclova Father , Jean-Christophe Meriaux
IPC分类号： G06Q30/00
CPC分类号： G06Q30/0603 , G06Q30/02 , G06Q30/0242 , G06Q30/0246 , G06Q30/0273
摘要： A method for determining the compensation due an affiliate from a merchant for traffic to a merchant Web site that originates from an affiliate Web site. The method may include steps of defining a plurality of compensation plans, exposing one or more of the plurality of compensation plans to the affiliate, the selected compensation plan(s) exposed to the affiliate being tailored to the affiliate and/or a product or service offered by the merchant; accepting a selection of compensation plans by the affiliate, and measuring traffic to the merchant Web site that originates from the affiliate Web site and applying the measured traffic to the compensation plan(s) selected by the affiliate to determine the compensation due to the affiliate.
摘要翻译：用于确定来自商家的会员从商业网站发送到商家网站的流量的补偿的方法。该方法可以包括以下步骤：定义多个补偿计划，将多个补偿计划中的一个或多个暴露给关联公司，暴露给关联公司的所选择的补偿计划被定制到关联公司和/或产品或服务由商家提供; 接受关联公司的选择的补偿计划，并测量从联属网站发起的商户网站的流量，并将测量的流量应用于由关联公司选择的补偿计划，以确定由该关联公司支付的赔偿。

2. 发明授权

US07575721B2 Method and apparatus for storing and dispensing reagent beads 有权
标题翻译：用于存储和分配试剂珠的方法和装置
公开(公告)号：US07575721B2
公开(公告)日：2009-08-18
申请号：US11146304
申请日：2005-06-06
申请人： Ronald Chang , Douglas B. Dority , Steven Michael Montgomery
发明人： Ronald Chang , Douglas B. Dority , Steven Michael Montgomery
IPC分类号： B01L3/00 , G01N31/00 , B01L3/02 , G01N21/03 , G01N1/00 , G01N33/543 , B23Q7/04 , G07F11/16 , B65H5/00 , B65H1/08 , B65H3/00
CPC分类号： B01L3/527 , B01J19/0046 , B01J2219/00468 , B01J2219/005 , B01J2219/00657 , B01L3/0289 , B01L2200/0647 , B01L2200/16 , G01N2035/00574 , Y10T436/25
摘要： Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In one embodiment, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.
摘要翻译：本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。在一个实施例中，提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置，其包括具有多个孔的珠粒载体; 设置在所述孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。该装置包括一个通道，在该通道中，珠子存放装置使胎圈承载件面向通道的支撑壁，盖带面向通道的剥离壁。剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙，以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上，以从胎圈载体上剥离覆盖带，以将通道内的胎圈载体的孔移动到分配开口，并单独暴露孔以分配试剂珠。

3. 发明授权

US07559479B2 Financial presentation instruments with integrated holder and methods for use 有权
标题翻译：具有综合持有人和使用方法的财务演示文书
公开(公告)号：US07559479B2
公开(公告)日：2009-07-14
申请号：US11849766
申请日：2007-09-04
申请人： Christopher McGee , Keith Newbrough , Kenneth Algiene
发明人： Christopher McGee , Keith Newbrough , Kenneth Algiene
IPC分类号： G06K7/00
CPC分类号： G06K19/04
摘要： The present invention provides improved apparatus, methods, and systems for displaying and packaging financial presentation instruments, particularly stored value, gift, or other pre-paid debit cards. In one embodiment of the present invention, a method for displaying a financial presentation instrument with an integrated holder is provided. The method comprises providing a data card having an information storage medium and an aperture therethrough. The data card is then suspended from a display hook through the at least one aperture. Hence, the present invention advantageously allows for convenient displaying and easy access to the data card for activation at the time the card is purchased by a consumer. Further, the integrated holder on the data card decreases the operating costs and increases the efficiency for selling such debit cards as no additional materials, packaging, or carriers other than the data card itself are needed for the presentation and display of such debit cards.
摘要翻译：本发明提供了用于显示和包装金融演示文书，特别是存储的价值，礼物或其他预付费借记卡的改进的装置，方法和系统。在本发明的一个实施例中，提供了一种用于显示具有集成保持器的财务呈现工具的方法。该方法包括提供具有信息存储介质和穿过其的孔径的数据卡。数据卡然后通过至少一个孔悬挂在显示钩上。因此，本发明有利地允许在消费者购买卡片时方便地显示和容易地访问数据卡以进行激活。此外，数据卡上的集成持有人降低了操作成本，并且提高了销售这种借记卡的效率，因为不需要除了数据卡本身之外的额外的材料，包装或载体来呈现和显示这样的借记卡。

4. 发明授权

US07431459B2 Slit lamp for ophthalmic use 有权
标题翻译：用于眼科用途的狭缝灯
公开(公告)号：US07431459B2
公开(公告)日：2008-10-07
申请号：US11969619
申请日：2008-01-04
申请人： Seema Somani
发明人： Seema Somani
IPC分类号： A61B3/10
CPC分类号： A61B3/135
摘要： A slit lamp for illuminating an eye comprises several LEDs electrically coupled to an LED driver. A user input accepts input for a length, a width and an intensity of a shaped beam of light. An LED driver selectively drives a set of LEDs of an LED array to form a shaped light beam having a desired size across a beam cross-section. In some embodiments, several optical fibers at a first end of a fiber optic manifold are optically coupled to LEDs of an LED array, and an optic is placed near a second end of a fiber optic manifold. Several ends of optical fibers of the fiber optic manifold are optically coupled to the set of selectively driven LEDs, and are arranged so as to form the shaped light beam having a desired size across the beam cross-section.
摘要翻译：用于照明眼睛的裂隙灯包括电耦合到LED驱动器的多个LED。用户输入接受成形光束的长度，宽度和强度的输入。 LED驱动器选择性地驱动LED阵列的一组LED以在束横截面上形成具有期望尺寸的成形光束。在一些实施例中，在光纤歧管的第一端处的若干光纤光学耦合到LED阵列的LED，并且光学元件放置在光纤歧管的第二端附近。光纤歧管的光纤的几个端部光耦合到一组选择性驱动的LED，并且被布置成在横截面上形成具有期望尺寸的成形光束。

5. 发明授权

US07430450B2 Device and method for treating obesity 有权
标题翻译：用于治疗肥胖症的装置和方法
公开(公告)号：US07430450B2
公开(公告)日：2008-09-30
申请号：US11281041
申请日：2005-11-16
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61N1/00
CPC分类号： A61N1/36007
摘要： A device and method are provided for treating obesity by implanting an electrode in the duodenum and stimulating the duodenum with a stimulator, causing the pylorus to contract.
摘要翻译：提供了通过将电极植入十二指肠并用刺激器刺激十二指肠来治疗肥胖的装置和方法，导致幽门收缩。

6. 发明授权

US07414144B2 Preparation of 2S,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride and other derivatives of 2-hydroxy-1,3-diamines 有权
标题翻译：制备2S，3S-N-异丁基-N-（2-羟基-3-氨基-4-苯基丁基） - 对硝基苯磺酰胺盐酸盐和2-羟基-1,3-二胺的其它衍生物
公开(公告)号：US07414144B2
公开(公告)日：2008-08-19
申请号：US11052934
申请日：2005-02-07
申请人： Aslam A. Malik , Hasan Palandoken , Joy A. Stringer , Roland P. Carlson , John Leach , Thomas G. Archibald , Robert G. Miotke
发明人： Aslam A. Malik , Hasan Palandoken , Joy A. Stringer , Roland P. Carlson , John Leach , Thomas G. Archibald , Robert G. Miotke
IPC分类号： C07C303/00
CPC分类号： C07C269/06 , C07C303/40 , C07C311/18 , C07C271/20
摘要： The present invention provides a new process for the preparation of 2S,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride, wherein this compound is prepared directly from the chloromethylalcohol. Importantly, the process of the present invention results in higher yields of 2S,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride without sacrificing its purity. The processes of the present invention can be used to prepare not only the 2S,3S-derivative, but also the 2R,3S-, 2S,2R- and the 2R,3R-derivatives.
摘要翻译：本发明提供了制备2S，3S-N-异丁基-N-（2-羟基-3-氨基-4-苯基丁基） - 对硝基苯磺酰胺盐酸盐的新方法，其中该化合物直接由氯甲基醇制备。重要的是，本发明的方法导致2S，3S-N-异丁基-N-（2-羟基-3-氨基-4-苯基丁基） - 对硝基苯磺酰胺盐酸盐的产率较高，而不牺牲其纯度。本发明的方法不仅可用于制备2S，3S-衍生物，还可制备2R，3S-，2S，2R-和2R，3R-衍生物。

7. 发明授权

US07377648B2 Volumetric point spread function for eye diagnosis and treatment 有权
标题翻译：眼睛诊断和治疗的体积点扩散功能
公开(公告)号：US07377648B2
公开(公告)日：2008-05-27
申请号：US11064876
申请日：2005-02-22
申请人： Erik Gross , Guangming Dai , Charles Campbell
发明人： Erik Gross , Guangming Dai , Charles Campbell
IPC分类号： A61B3/00
CPC分类号： A61B3/0025 , A61F2009/00872
摘要： Systems and methods analyze, diagnose, and/or treat a patient's eye using modified forms of the point spread function (“PSF”) tailored to the vision system. Factors that alter perception of visual aberrations can be included and/or volumetric point spread functions calculated, often using point spread function calculations throughout a range of optical distances to more fully indicate the variation in visual perception of optics at different distances. A variety of visual affects of the human optical system can be simulated, analyzed, and modeled, including: single versus multiple wavelength sources, chromatic aberrations, retinal resolution, wavelength-dependent visual response, Stiles-Crawford effects, and/or non-linearity of retinal response. The perceived point spread function can offer objective confirmation of the patient's visual perception, allow a treating physician to see a closer approximation of what the patient sees, indicate the scale and significance of wavefront aberrations, and/or show which aberrations affect vision and which do not.
摘要翻译：系统和方法使用针对视觉系统定制的点扩散功能（“PSF”）的修改形式来分析，诊断和/或治疗患者的眼睛。可以包括改变视觉异常感知的因素和/或体积点扩散函数，通常在光学距离范围内使用点扩散函数计算，以更完全地指示不同距离的光学器件的视觉感知的变化。可以模拟，分析和建模人类光学系统的各种视觉影响，包括：单波长与多波长源，色差，视网膜分辨率，波长依赖视觉反应，Stiles-Crawford效应和/或非线性的视网膜反应。感知点扩散功能可以提供患者视觉感知的客观确认，允许治疗医师看到患者看到的更接近的近似值，指示波前像差的尺度和显着性，和/或显示哪些像差影响视力，哪些不。

8. 发明授权

US07358040B2 MRE 11: modulation of cellular proliferation 失效
标题翻译： MRE 11：调节细胞增殖
公开(公告)号：US07358040B2
公开(公告)日：2008-04-15
申请号：US10026331
申请日：2001-12-21
申请人： Yasumichi Hitoshi , Susan Demo , Yonchu Jenkins
发明人： Yasumichi Hitoshi , Susan Demo , Yonchu Jenkins
IPC分类号： C12Q1/00
CPC分类号： C12Q1/34 , G01N33/5011 , G01N33/573 , G01N2333/922 , G01N2500/02
摘要： The present invention relates to regulation of cellular proliferation. More particularly, the present invention is directed to nucleic acids encoding MRE11, which is a protein involved in modulation of cellular proliferation. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions, antibodies, peptides, cyclic peptides, nucleic acids, antisense nucleic acids, and ribozymes, that modulate cellular proliferation via modulation of MRE11; as well as to the use of expression profiles and compositions in diagnosis and therapy related to modulation of cellular proliferation.
摘要翻译：本发明涉及细胞增殖的调控。更具体地，本发明涉及编码MRE11的核酸，其是涉及细胞增殖调节的蛋白质。本发明还涉及用于鉴定和使用通过调节MRE11来调节细胞增殖的试剂，包括小分子化学组合物，抗体，肽，环肽，核酸，反义核酸和核酶的方法; 以及在与调节细胞增殖相关的诊断和治疗中使用表达谱和组合物。

9. 发明授权

US07309803B2 Clean, High-yield preparation of S,S and R,S amino acid isosteres 有权
标题翻译：清洁，高产量的S，S和R，S氨基酸等体积的制备
公开(公告)号：US07309803B2
公开(公告)日：2007-12-18
申请号：US11081106
申请日：2005-03-14
申请人： Aslam A. Malik , Todd E. Clement , Hasan Palandoken , James Robinson, III , Joy A. Stringer
发明人： Aslam A. Malik , Todd E. Clement , Hasan Palandoken , James Robinson, III , Joy A. Stringer
IPC分类号： C07C205/02
CPC分类号： C07C271/22 , C07B2200/09 , C07C213/00 , C07D263/20 , C07D303/36 , C07C215/08
摘要： The present invention provides compounds and methods that can be used to convert the intermmediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
摘要翻译：本发明提供可用于将中间卤代甲基酮（HMK）如氯甲基酮转化成相应的S，S-和R，S-非对映异构体的化合物和方法。更具体地说，本发明提供：（1）还原方法; （2）反演方法; 和（3）涉及烯烃环氧化的方法。使用本发明的各种方法，可以高产率和高纯度可靠地制备R，S-环氧化物和中间体化合物。

10. 发明授权

US07298873B2 Multimodal biometric platform 有权
标题翻译：多式联运生物识别平台
公开(公告)号：US07298873B2
公开(公告)日：2007-11-20
申请号：US10991352
申请日：2004-11-16
申请人： S. James Miller, Jr. , William Frederic Willis , Johann Herbert Lau , Daniel Dlab
发明人： S. James Miller, Jr. , William Frederic Willis , Johann Herbert Lau , Daniel Dlab
IPC分类号： G06K9/00 , G05B19/00
CPC分类号： G06K9/00885 , G06K9/00979
摘要： A multimodal biometric identification or authentication system includes a plurality of biometric clients. Each of the biometric clients may include devices for capturing biometric images of a plurality of types. The system includes a router in communication with the biometric clients. The router receives biometric images from, and returns biometric scores or results to, the biometric clients. The system includes a plurality of biometric matching engines in communication with the router. Each biometric matching engine includes multiple biometric processors. Each biometric processor is adapted to process biometric data of a particular type. The biometric matching engines transmit and receive biometric data to and from the router.
摘要翻译：多模态生物识别或认证系统包括多个生物特征客户端。每个生物测定客户端可以包括用于捕获多种类型的生物统计图像的设备。该系统包括与生物特征客户端通信的路由器。路由器从生物识别客户端接收生物特征图像，并将生物特征分数或结果返回给生物识别客户端。该系统包括与路由器通信的多个生物特征匹配引擎。每个生物特征匹配引擎包括多个生物识别处理器。每个生物测定处理器适于处理特定类型的生物特征数据。生物特征匹配引擎向路由器发送和接收生物特征数据。

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