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1. 发明授权

US5707376A Stent introducer and method of use 失效
标题翻译：支架导引器及使用方法
公开(公告)号：US5707376A
公开(公告)日：1998-01-13
申请号：US475117
申请日：1995-06-07
申请人： Zaza A. Kavteladze , Aleksandr P. Korshok , Scott E. Boatman
发明人： Zaza A. Kavteladze , Aleksandr P. Korshok , Scott E. Boatman
IPC分类号： A61F2/00 , A61F2/90 , A61B17/00
CPC分类号： A61F2/90 , A61F2/95 , A61F2002/9517 , A61F2210/0019 , A61F2250/0098
摘要： An introducer (10) method of percutaneously deploying a self-expanding stent (14) in a body vessel or duct (43). The stent introducer includes an outer elongated member tube (11) having a passage (12) extending longitudinally therein and operable in a first direction (13) for deploying the self-expanding stent in a collapsed condition from the outer member passage. An inner elongated member (15) is positioned in the outer member passage and is operable in a second direction (16) for deploying the stent from the outer member passage. An interconnection mechanism (17) is connected to the outer and inner members for operation thereof, whereby a stent in a collapsed condition is deployed from the outer member passage to an expanded condition. When deployed, the expanded portion of the stent remains fixedly positioned longitudinally in the body vessel or duct as the remaining portion is deployed from the outer member passage. The inner member operates a second operable distance (34) and includes at least one protuberance (19) for pushing the stent out of the outer member passage as the outer member is concomitantly withdrawn a first operable distance (33) from the collapsed, self-expanding stent. The first operable distance is the short length (36) of the stent in an expanded condition, whereas the second operable distance (34) is approximately the distance (37) in the long and short lengths of the stent. The interconnection mechanism of the introducer further includes a transfer assembly (23) coupled to the outer and inner members for controlling the travel distance and direction thereof.
摘要翻译：一种在身体容器或管道（43）中经皮展开自扩张支架（14）的导引器（10）方法。支架引导器包括外部细长构件管（11），其具有在其中纵向延伸的通道（12），并且可在第一方向（13）上操作，用于将展开状态的自扩张支架从外部构件通道展开。内部细长构件（15）定位在外部构件通道中并且可在第二方向（16）上操作以用于从外部构件通道展开支架。互连机构（17）连接到外部构件和内部构件用于操作，由此将处于折叠状态的支架从外部构件通道展开到展开状态。当部署时，随着剩余部分从外部构件通道展开，支架的扩张部分保持固定地纵向地定位在身体容器或管道中。内部构件操作第二可操作距离（34），并且包括至少一个用于将支架从外部构件通道推出的突起（19），因为外部构件被同时撤回与折叠的自对准的第一可操作距离（33）扩张支架第一可操作距离是扩张状态下支架的短长度（36），而第二可操作距离（34）大约是支架的长和短长度中的距离（37）。引导器的互连机构还包括联接到外部和内部构件的传送组件（23），用于控制行进距离和方向。

2. 发明授权

US5683411A Medical article for implantation into the vascular system of a patient 失效
标题翻译：用于植入患者血管系统的医疗用品
公开(公告)号：US5683411A
公开(公告)日：1997-11-04
申请号：US464698
申请日：1995-06-07
申请人： Zaza A. Kavteladze , Aleksandr P. Korshok
发明人： Zaza A. Kavteladze , Aleksandr P. Korshok
IPC分类号： A61B17/00 , A61B17/12 , A61F2/01 , C09C1/00 , C09C1/40 , A61M29/00 , A61F2/04
CPC分类号： A61F2/01 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/0078 , A61F2230/008
摘要： A medical article for implantation into the vascular system of a patient comprises a self expanding body shaped substantially into the form of a body (1; 2) of revolution, at least part of the surface of which is defined by wire members (3) forming cells of a generally polygonal shape. The body of revolution has a diameter increasing continuously in an axial direction of the body from one end forming an apex (4) towards the opposite end forming a base (5). In a preferred embodiment, the body (1; 2) of revolution is defined by a generatrix forming n-th order curve. The article may comprise two bodies (1; 2) of revolution joined at their apices (4). The article may be used, in particular as an intravenous filter for the capture of thrombi or in combination with an elastic blood impermeable membrane flexibly linked to the apex of the body of revolution as an occlusion device for closing a vessel lumen or defects such as ASD or PDA in vascular walls.
摘要翻译： PCT No.PCT / DK95 / 00147 Sec。 371日期：1995年6月7日 102（e）日期1995年6月7日PCT提交1995年4月6日PCT公布。 WO95 / 27448 PCT公开号 1995年10月19日的日期用于植入患者血管系统的医疗制品包括基本上形成为旋转体（1,2）形式的自膨胀体，其表面的至少一部分由电线构件（3）形成大致多边形形状的单元。旋转体的直径从形成顶点（4）的一端向形成基部（5）的相对端的直径沿主体的轴向方向连续地增加。在优选实施例中，旋转体（1; 2）由形成n阶曲线的母线限定。物品可以包括在其顶点（4）处连接的两个旋转体（1; 2）。该物品可以特别用作静脉内过滤器，用于捕获血栓，或与弹性血液不可渗透膜组合使用，弹性血液不可渗透膜作为关闭血管腔的闭塞装置或诸如ASD的缺陷而灵活地连接到旋转体的顶点或PDA在血管壁。

3. 发明授权

US5643339A Prosthetic device for sustaining a blood-vessel or hollow organ lumen 失效
标题翻译：用于维持血管或中空器官腔的假体装置
公开(公告)号：US5643339A
公开(公告)日：1997-07-01
申请号：US379582
申请日：1995-02-01
申请人： Zaza A. Kavteladze , Aleksandr P. Korshok , Andrej A. Kadnikov
发明人： Zaza A. Kavteladze , Aleksandr P. Korshok , Andrej A. Kadnikov
IPC分类号： A61F2/00 , A61F2/90 , A61F2/95 , A61F2/06
CPC分类号： A61F2/90 , A61F2/95 , A61F2002/9511 , A61F2210/0019
摘要： A prosthetic device for sustaining a vessel or hollow organ lumen (a stent) has a tubular wire frame (1) with rows of elongate cells (2) having a larger axis and a smaller axis. The cells are arranged with the larger axis in the circumferential direction of the frame (2) and the smaller axis parallel to the axial direction thereof. Each cell is formed by two U-shaped wire sections, and in a plane perpendicular to the longitudinal axis one of the branches of the U-shaped wire sections in one row form together a closed ring-shape (4) which provides the frame (1) with large radial stiffness. In the axial direction the frame (1) has only low stiffness so that it easily conforms to the vascular wall even if this deforms due to external loads. The interconnection between the cells (2) may be flexible.
摘要翻译： PCT No.PCT / DK93 / 00256 Sec。 371日期：1995年2月1日 102（e）1995年2月1日PCT PCT 1993年8月6日PCT公布。公开号WO94 / 03127 日期1994年2月17日用于维持血管或中空器官腔（支架）的假体装置具有管状线框架（1），其具有具有较大轴线和较小轴线的细长细胞排（2）。电池在框架（2）的圆周方向上具有较大的轴线，并且平行于其轴向的较小的轴线布置。每个电池由两个U形电线部分形成，并且在垂直于纵向轴线的平面中，一行中的U形电线部分的一个分支形成一个提供框架的闭合环形（4） 1）径向刚度较大。在轴向方向上，框架（1）仅具有低刚度，使得其容易地符合血管壁，即使由于外部载荷而变形。单元（2）之间的互连可以是柔性的。

4. 发明授权

US5562697A Self-expanding stent assembly and methods for the manufacture thereof 失效
标题翻译：自扩张支架组件及其制造方法
公开(公告)号：US5562697A
公开(公告)日：1996-10-08
申请号：US529474
申请日：1995-09-18
申请人： Frank K. Christiansen
发明人： Frank K. Christiansen
IPC分类号： A61F2/86 , A61M29/00 , A61F2/04 , A61F2/06
CPC分类号： A61F2/86 , A61F2/07 , A61F2002/072 , A61F2002/075 , A61F2220/005 , A61F2220/0075
摘要： A self-expanding stent assembly and methods for the manufacture thereof and for introduction of such a stent assembly into a body passage or duct of a patient. A self-expanding endovascular stent assembly comprises at least one stent segment (7, 8) formed by a single piece of wire arranged in a closed zig-zag configuration with struts (10) joining each other joints (11) and a covering sleeve (9). The stent segment (7, 8) is compressible from an expanded condition with a first radius (R) into an introduction condition with second radius (r). The struts (10) are retained solely by the sleeve (9), which is relatively inelastic and has a thickness of not more than 1 percent of the first radius (R).
摘要翻译：一种自扩张支架组件及其制造方法以及用于将这种支架组件引入患者的身体通道或管道中的方法。自扩张型血管内支架组件包括至少一个支架段（7,8），该支架段由以一个闭合的之字形配置布置的单片导线形成，支柱（10）将彼此接合（11）和覆盖套 9）。支架段（7,8）从具有第一半径（R）的扩张状态可压缩成具有第二半径（r）的引入条件。支柱（10）仅由相对非弹性的套筒（9）保持，并且具有不大于第一半径（R）的1％的厚度。

5. 发明授权

US07892254B2 Embolization method for endovascular occlusion 有权
标题翻译：栓塞栓塞方法
公开(公告)号：US07892254B2
公开(公告)日：2011-02-22
申请号：US10813783
申请日：2004-03-30
申请人： Henrik S. Klint , Arne Molgaard-Nielsen , Erik E. Rasmussen
发明人： Henrik S. Klint , Arne Molgaard-Nielsen , Erik E. Rasmussen
IPC分类号： A61B17/08 , A61M29/00 , A61F2/02
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B17/12172 , A61B2017/12095
摘要： An embolization device for positioning in a blood vessel comprises an elongated wire body (1) which in its unloaded condition has a predetermined shape and has an elongated shape with a substantially straight center line during its insertion through a catheter (18) to a placement site in the blood vessel and after its release from the catheter assumes a complexly curved shape which depends on the predetermined shape and on the blood vessel impact on the wire body. In its predetermined shape the wire body has at least one section (4) located between its front and back ends in which the center line has substantially no curvature or such a small curvature that along a length of at least 20 mm it follows a helix-free path. The front end section (2, 2″, 2′″) of the wire body is adapted to be frictionally locked to the vessel wall when discharged from the catheter, before said helix-free section (4) has been discharged from the catheter. When the helix-free section (4) is discharged it will bend sideways and seek towards the middle of the vessel lumen and continue towards the opposite vessel wall where it is frictionally locked. At continued pushing out many such vessel-crossing wire portions (20) occur, which provides efficient occlusion of the vessel. One advantage of the embolization device is that it may be used to occlude blood vessel areas. Accordingly, a method is described for occluding a blood vessel area using the wire body (1).
摘要翻译：用于定位在血管中的栓塞装置包括细长线体（1），其在其卸载状态下具有预定形状并且具有细长形状，在其通过导管（18）插入到放置位置时具有基本上直的中心线在血管中并且在其从导管释放之后呈现出取决于预定形状和血管对线体的冲击的复杂曲线形状。在其预定形状中，线体具有位于其前端和后端之间的至少一个部分（4），其中中心线基本上没有曲率或沿着至少20mm的长度的曲率，自由之路线体的前端部分（2,2'，2“）适于在从导管排出之前，在从导管排出所述无螺旋部分（4）之前摩擦地锁定到血管壁。当无螺旋部分（4）被排出时，它将侧向弯曲并且朝着血管腔的中间寻求并且继续朝向相对的血管壁，在那里被摩擦锁定。继续推出许多这样的容器交叉电线部分（20），这提供了容器的有效闭塞。栓塞装置的一个优点是可用于阻塞血管区域。因此，描述了使用线体（1）闭塞血管区域的方法。

6. 发明授权

US5133733A Collapsible filter for introduction in a blood vessel of a patient 失效
标题翻译：用于介绍患者血管的可抽吸过滤器
公开(公告)号：US5133733A
公开(公告)日：1992-07-28
申请号：US606588
申请日：1990-10-31
申请人： Erik Rasmussen , Rolf W. Gunther
发明人： Erik Rasmussen , Rolf W. Gunther
IPC分类号： A61B17/00 , A61F2/01 , A61F2/02 , A61M1/16
CPC分类号： A61F2/01 , A61F2002/016 , A61F2230/005 , A61F2230/008
摘要： In a collapsible filter for introduction into a blood vessel of a patient and of the kind comprising a number of legs (1-4) diverging from an apical hub (5) and each having a reversely turned hook (1b-4b) at its distal end with respect to said hub (5), each leg comprises a central element (1a-4a), bent into a smooth quasi-half sinusoidal form, and two substantially symmetrical curved side elements (1c-4c, 1d-4d) extending on either side of the central element (1a-4a). The filter may as whole may be unfolded from a collapsed insertion condition in which the central and side elements of all legs (1-4) forms a narrow bundle for arrangement in a catheter like insertion instrument into a tulip like filter configuration with the side elements (1c-4c, 1d-4d) interposed between the central elements (1a-4a) of the legs.

7. 发明授权

US5630823A Apparatus for fragmentation of a lung or heart embolus 失效
标题翻译：用于肺或心脏栓塞破裂的装置
公开(公告)号：US5630823A
公开(公告)日：1997-05-20
申请号：US459272
申请日：1995-06-02
申请人： Thomas Schmitz-Rode , Rolf W. Gunther
发明人： Thomas Schmitz-Rode , Rolf W. Gunther
IPC分类号： A61B17/22 , A61M25/00
CPC分类号： A61M25/0041 , A61B17/221 , A61B17/320725 , A61B17/320758 , A61B2017/320733
摘要： Method and apparatus for fragmentation of a lung embolus. The apparatus includes a catheter that is introduced over a guide wire to the site of the lung embolism in the vascular system of a patient. When the guide wire is withdrawn from the distal end segment of the catheter, the distal end segment bends back proximally. An opening in the bend of the catheter is in line with the central axis of the catheter when the distal end segment is in a curved configuration. The guide wire is then advanced to extend distally from the catheter opening past the embolism and stabilize the longitudinal position of the catheter in the blood vessel. The apparatus also includes a thread for pulling the bent distal end segment into a generally oval-shaped loop condition and stabilizing the loop about the embolism. The looped catheter is then rotated and moved longitudinally back and forth for mechanically destroying the embolism. To return the catheter to a straight condition, the rigid guide wire is withdrawn from the catheter, and a guide wire with a resilient J-tip is advanced to the distal end segment of the catheter. The J-tip guide wire follows the catheter past the catheter opening, thereby straightening the catheter for removal from the body. The apparatus optionally includes a handle or motor positioned at the proximal end of the apparatus.
摘要翻译：肺栓塞破裂的方法和装置。该装置包括导管，导管穿过患者血管系统中的肺栓塞部位。当引导线从导管的远端部分撤出时，远端部分向近侧弯曲。当远端段处于弯曲形状时，导管弯曲处的开口与导管的中心轴线一致。导丝然后前进以从导管开口向远侧延伸穿过栓塞，并将导管的纵向位置稳定在血管中。该装置还包括用于将弯曲的远端段拉伸成大致椭圆形的环状并且围绕栓塞稳定环的螺纹。然后将环形导管旋转并纵向前后移动以机械地破坏栓塞。为了将导管返回到直线状态，刚性导丝从导管中取出，并且具有弹性J型尖端的引导线前进到导管的远端段。 J型引导线沿着导管穿过导管开口，从而矫正导管以从体内移除。该设备可选地包括位于设备近端的手柄或马达。

8. 发明授权

US5324304A Introduction catheter set for a collapsible self-expandable implant 失效
标题翻译：介绍用于可折叠自扩张植入物的导管
公开(公告)号：US5324304A
公开(公告)日：1994-06-28
申请号：US900978
申请日：1992-06-18
申请人： Erik E. Rasmussen
发明人： Erik E. Rasmussen
IPC分类号： A61F2/01 , A61B17/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/005 , A61F2230/0076 , A61F2230/008
摘要： An introduction catheter set for a collapsible, self-expandable implant of the type comprising a number of spring-biased anchoring legs, e.g. a filter for entrapping thrombi or emboli into a blood vessel of a patient comprises a flexible external guide sheath and a flexible internal catheter slidably displaceable inside the guide sheath and having at its distal end a tubular end member, in which a retaining member is slidably arranged for releasably retaining the anchoring legs of the implant in defined angular positions in respect of each other. The retaining member is connected with a flexible displacement member extending throughout the internal catheter with the proximal ends of the displacement member and the internal catheter connected with a first and a second operating member, respectively. By operation of the operating members the retaining member may be displaced in the tubular end member from a retaining position, in which the anchoring legs of the implant are inside the tubular end member which protrudes from the distal end of the external sheath, to a release position, in which the retaining member protrudes from the tubular end member to release the anchoring legs of the implant.
摘要翻译：一种用于可折叠的，可膨胀的植入物的引入导管，其包括多个弹簧偏置的锚定腿，例如，用于将血栓或栓塞截留到患者的血管中的过滤器包括柔性外部引导护套和可在引导护套内部可滑动地移位的柔性内部导管，并且在其远端处具有管状端部构件，其中保持构件可滑动地布置在其中用于将植入物的锚固腿可释放地保持在相对于彼此的限定的角位置。保持构件连接有贯穿整个内部导管延伸的柔性位移构件，移位构件的近端和内部导管分别与第一和第二操作构件连接。通过操作构件的操作，保持构件可以在管状端构件中从保持位置移位，其中植入物的锚定腿在从外护套的远端突出的管状端构件内部到释放位置位置，其中保持构件从管状端构件突出以释放植入物的锚定腿。

9. 外观设计

USD300060S Biopsy cannula 失效
公开(公告)号：USD300060S
公开(公告)日：1989-02-28
申请号：US763609
申请日：1985-08-08
申请人： Arne Molgaard-Nielsen
设计人： Arne Molgaard-Nielsen

10. 发明申请

US20040186491A1 Embolization method for endovascular occlusion 有权
标题翻译：栓塞栓塞方法
公开(公告)号：US20040186491A1
公开(公告)日：2004-09-23
申请号：US10813783
申请日：2004-03-30
申请人： William Cook, Europe A/S
发明人： Henrik S. Klint , Arne Molgaard-Nielsen , Erik E. Rasmussen
IPC分类号： A61B017/08
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B17/12172 , A61B2017/12095
摘要： An embolization device for positioning in a blood vessel comprises an elongated wire body (1) which in its unloaded condition has a predetermined shape and has an elongated shape with a substantially straight center line during its insertion through a catheter (18) to a placement site in the blood vessel and after its release from the catheter assumes a complexly curved shape which depends on the predetermined shape and on the blood vessel impact on the wire body. In its predetermined shape the wire body has at least one section (4) located between its front and back ends in which the center line has substantially no curvature or such a small curvature that along a length of at least 20 mm it follows a helix-free path. The front end section (2, 2null, 2nullnull) of the wire body is adapted to be frictionally locked to the vessel wall when discharged from the catheter, before said helix-free section (4) has been discharged from the catheter. When the helix-free section (4) is discharged it will bend sideways and seek towards the middle of the vessel lumen and continue towards the opposite vessel wall where it is frictionally locked. At continued pushing out many such vessel-crossing wire portions (20) occur, which provides efficient occlusion of the vessel.
摘要翻译：用于定位在血管中的栓塞装置包括细长线体（1），其在其卸载状态下具有预定形状并且具有细长形状，在其通过导管（18）插入到放置位置时具有基本上直的中心线在血管中并且在其从导管释放之后呈现出取决于预定形状和血管对线体的冲击的复杂曲线形状。在其预定形状中，线体具有位于其前端和后端之间的至少一个部分（4），其中中心线基本上没有曲率或沿着至少20mm的长度的曲率，自由之路线体的前端部分（2,2“，2”）适于在从导管排出之前摩擦地锁定到容器壁上，在所述无螺旋部分（4）从导管。当无螺旋部分（4）被排出时，它将侧向弯曲并且朝着血管腔的中间寻求并且继续朝向相对的血管壁，在那里被摩擦锁定。继续推出许多这样的容器交叉电线部分（20），这提供了容器的有效闭塞。

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