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1. 发明申请

US20170120235A1 Pipette Comprising Imaging Device Element 审中-公开
公开(公告)号：US20170120235A1
公开(公告)日：2017-05-04
申请号：US15317481
申请日：2015-06-05
申请人： Thermo Fisher Scientific Oy
发明人： Juha Miettinen , Mikael Lind , Juha Telimaa
IPC分类号： B01L3/02 , H04N5/232 , H04N7/18 , G01N35/10
CPC分类号： B01L3/0237 , B01L3/0217 , B01L2200/143 , B01L2300/021 , B01L2300/027 , B01L2300/0654 , G01N35/1011 , G02B27/028 , H04N5/23293 , H04N7/18
摘要： A pipette comprising a cylinder with a piston movable inside the cylinder for aspiring and dispensing liquid, and a handle portion for gripping the pipette, wherein the pipette further comprises an imaging device element for obtaining images that assist the use of the pipette.

2. 发明授权

US11420820B2 Waste bin carrier and automated receptacle handling system 有权
公开(公告)号：US11420820B2
公开(公告)日：2022-08-23
申请号：US16612779
申请日：2018-05-08
申请人： Thermo Fisher Scientific Oy
发明人： Jarkko Panu , Ville Mäkelä , Sami Paavilainen
IPC分类号： B65F1/14 , B01L9/00 , B01L1/00 , B62B3/04 , B62B3/10
摘要： A novel waste bin carrier (100) is proposed for carrying at least one waste bin (200). The waste bin carrier (100) includes a frame (110) having a base (130) for receiving thereon one waste bin (200) or more. The waste bin carrier (100) also has a locking mechanism (120) movably attached to the frame (110) for releasably securing at least one waste bin (200) to the waste bin carrier (100). The locking mechanism (120) has a pusher guide (121) that extends in a first horizontal Cartesian dimension (X) for lateral engagement with the waste bin (200). The locking mechanism also has at least one articulated arm (122) that connects the pusher guide (121) to the frame (110) of the waste bin carrier (100) for allowing movement of the pusher guide (121) in respect to the frame (110) between the deployed state and the released state.

3. 发明申请

US20210268509A1 Sample vessel rack, method for locking sample vessels in a sample vessel rack and sample vessel rack system 有权
公开(公告)号：US20210268509A1
公开(公告)日：2021-09-02
申请号：US17140601
申请日：2021-01-04
申请人： THERMO FISHER SCIENTIFIC OY
发明人： Lauri PELTOSAARI
IPC分类号： B01L9/06 , B01L3/00 , G01N30/24 , G01N35/04
摘要： A sample vessel rack (1), which comprises a frame (2) with a plurality of openings (3) in the upper surface of the frame for sample vessels (9), and a locking plate member (5) movable in a plane parallel to the upper surface of the frame (2) of the rack from a releasing position to a locking position and back, wherein the removal of the sample vessels (9) from the rack is prevented when the locking plate member is in the locking position, the openings (3) of the upper surface of the frame (2) comprises slots (12) formed on their side, and in the locking position a part of the locking plate member (5) sets itself in the area of the slots. The invention also relates to such a method and a sample vessel rack system.

4. 发明授权

US10739321B2 Automated system for sample preparation and analysis 有权
公开(公告)号：US10739321B2
公开(公告)日：2020-08-11
申请号：US16118043
申请日：2018-08-30
申请人： Thermo Fisher Scientific Oy
发明人： Robert DeWitte , Juhani Siidorov , Vesa Nuotio , Raimo Salminen , Jarmo Vehkomaki , Jukka Saukkonen , Bill Ostman , Joseph M. Senteno , John Edward Brann, III , Joseph L. Herman , Jeffrey A. Zonderman , Terry N. Olney
IPC分类号： G01N30/72 , G01N30/06 , G01N30/86 , G01N35/00 , G01N35/08 , G01N35/02 , G01N27/62 , H01J49/04 , H01J49/00 , H01J49/10 , G01N30/88 , G01N30/16 , G06F19/00 , G01N30/02 , G01N30/62
摘要： A method of multiplexing the operation of a sample preparation and analysis system is disclosed. The system includes a sample preparation system capable of preparing a first sample in accordance with a first assay that is selected from a database containing a plurality of unique assays and preparing a second sample in accordance with a second, different assay. The method includes separately transporting the first and second prepared samples to an analysis station having first and second separation channels and an analyzer comprising a mass spectrometer. The method further includes simultaneously analyzing the first prepared sample with the analyzer in accordance with the first selected assay and separating the second prepared sample with the second separation channel in accordance with the second selected assay.

5. 发明授权

US10350589B2 Pipette comprising imaging device element 有权
公开(公告)号：US10350589B2
公开(公告)日：2019-07-16
申请号：US16145380
申请日：2018-09-28
申请人： Thermo Fisher Scientific Oy
发明人： Juha Miettinen , Mikael Lind , Juha Telimaa
IPC分类号： B01L3/02 , G01N35/10 , G02B27/02 , H04N5/232 , H04N7/18
摘要： A pipette comprising a cylinder with a piston movable inside the cylinder for aspiring and dispensing liquid, and a handle portion for gripping the pipette, wherein the pipette further comprises an imaging device element for obtaining images that assist the use of the pipette.

6. 发明授权

US10088460B2 Automated system for sample preparation and analysis 有权
公开(公告)号：US10088460B2
公开(公告)日：2018-10-02
申请号：US13882393
申请日：2011-10-28
申请人： Robert DeWitte , Juhani Siidorov , Vesa Nuotio , Raimo Salminen , Jarmo Vehkomaki , Jukka Saukkonen , Bill Ostman , Joseph M. Senteno , John Edward Brann, III , Joseph L. Herman , Jeffrey A. Zonderman , Terry N. Olney
发明人： Robert DeWitte , Juhani Siidorov , Vesa Nuotio , Raimo Salminen , Jarmo Vehkomaki , Jukka Saukkonen , Bill Ostman , Joseph M. Senteno , John Edward Brann, III , Joseph L. Herman , Jeffrey A. Zonderman , Terry N. Olney
IPC分类号： G01N30/72 , G01N30/06 , G01N30/86 , G01N35/00 , G01N35/02 , G01N35/08 , G01N27/62 , H01J49/04 , H01J49/00 , H01J49/10 , G01N30/88 , G01N30/16 , G01N30/02 , G01N30/62
摘要： A sample preparation and analysis system. The system 10 includes a sample preparation system 12 and a sample analysis system 14. The sample preparation system 12 prepares samples in accordance with an assay that is selected from a database containing a plurality of unique assays. The sample analysis system 14 includes an analyzer 110 that is dynamically reconfigurable based on the selected assay so as to analyze the prepared sample in accordance with that selected assay. A data communication link 27 communicates data from the sample preparation system 12 to the sample analysis system 14 to reconfigure the analyzer 110 in accordance with the selected assay.

7. 发明申请

US20180128721A1 METHOD AND APPARATUS FOR AUTOMATED ANALYSIS 审中-公开
公开(公告)号：US20180128721A1
公开(公告)日：2018-05-10
申请号：US15681702
申请日：2017-08-21
申请人： THERMO FISHER SCIENTIFIC OY
发明人： Sari TIKANOJA , Annu SUONIEMI , Johan FINELL
IPC分类号： G01N1/40 , G01N35/02 , G01N35/04 , G01N35/10
CPC分类号： G01N1/405 , G01N35/025 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/1032
摘要： An apparatus for pretreatment of a desired sample in a discrete fluid analyzing instrument includes a frame rotatably mounted on or within the discrete fluid analyzing instrument with a column for immobilizing at least one substance or analyte from the sample. The substance or analyte is reversibly immobilized. A first fluid transport line is provided for aspirating the sample into the column and for ejecting the substance or analyte eluted from the column. A pump is provided for pumping the sample through the column with a second fluid transport line connecting the pump to the column. A member is providing to supply the eluted substance or analyte to the discrete fluid analyzing instrument for measurement of at least one property of the substance or analyte. A device is provided for simultaneously or consecutively directing any non-pretreated sample or any subsample directly to the discrete fluid analyzing instrument.

8. 发明授权

US09804182B2 Handling package of cuvettes 有权
公开(公告)号：US09804182B2
公开(公告)日：2017-10-31
申请号：US13522136
申请日：2011-02-22
申请人： Vesa Nuotio , Juhani Makunen
发明人： Vesa Nuotio , Juhani Makunen
IPC分类号： B65D85/00 , G01N35/02
CPC分类号： G01N35/026
摘要： Automatic analyzers, in which the liquids to be analyzed are in so-called reaction vessels, simultaneously acting as optically high-quality cuvettes (10), are used in laboratories for analyzing various liquids. Further described is a handling package for cuvettes (10). A removable bonding strip (100) is fastened on the rows of cuvettes (10), the strip (100) binding the rows of cuvettes (10) during transport, and being easily removable when the cuvettes (10) are loaded into the instrument. The cuvettes (10) are loaded into the instrument by supporting the package in its place from the brackets (24) located in the ends of the cuvettes (10), so that the strip (100) can be pulled off the supported package of cuvettes (10).

9. 发明授权

US09720007B2 Method and assembly for transporting single and multiple reaction vessels 有权
公开(公告)号：US09720007B2
公开(公告)日：2017-08-01
申请号：US13824167
申请日：2011-10-28
申请人： Vesa Nuotio
发明人： Vesa Nuotio
IPC分类号： B65G1/04 , B01L3/00 , G01N35/00 , B01L9/06 , B25J11/00 , B25J15/12 , B25J15/04
CPC分类号： G01N35/0099 , B01L9/06 , B25J11/00 , B25J15/04 , B25J15/12
摘要： A method and apparatus for transporting single and multiple reaction vessels. At least one reaction vessel is provided and at least one tray includes at least two seats for the at least one reaction vessel, and at least one gripper. One of the reaction vessel or the tray is engaged with the gripper at a first position. The gripped element is transported to a second position wherein the gripper is released. A gripping collar is provided both on the reaction vessel and the tray for the gripper to engage. At one transport stage one of the reaction vessel or the tray is engaged with the gripper at a first position by pushing the gripper from above to engage with the gripping collar and in a second stage the transported element is disengaged from the gripper by moving the gripper sideways in relation to the center axis of the gripping collar.

10. 发明授权

US09566580B2 Sealed pipette 有权
标题翻译：密封移液器
公开(公告)号：US09566580B2
公开(公告)日：2017-02-14
申请号：US13970722
申请日：2013-08-20
申请人： THERMO FISHER SCIENTIFIC OY
发明人： Ari Jaaskelainen , Mikael Lind , Juha Telimaa , Aaro Tuominen
IPC分类号： B01L3/02 , B01L3/00 , G01N35/10
CPC分类号： B01L3/0275 , B01L3/021 , B01L3/0217 , B01L2200/02 , B01L2200/025 , B01L2400/0478 , G01N35/1074 , Y10T29/49826
摘要： The invention relates to liquid dispensing and concerns a pipette comprising at least one aspiration channel with a piston. At the lower end of the aspiration channel there is an extension channel (3) and at its end a pipette tip mounting piece (4) onto which a pipette tip (5) is attached. On the pipette tip mounting piece there is a surrounding groove (17) and in the groove a sealing ring (18). The width of the groove in the axial direction is at least 1.1 times the thickness of the sealing ring in the axial direction. When the mounting piece is pushed into the pipette tip, the inner wall of the tip can move the sealing ring upwards in the groove. The construction can provide a reliable sealing despite of inherent dimension differences between different tips and mounting pieces.
摘要翻译：本发明涉及液体分配，涉及包括至少一个具有活塞的抽吸通道的移液管。在抽吸通道的下端具有延伸通道（3），并在其末端附接吸移管尖端（5），移液管尖端安装件（4）。在移液管末端安装件上有一个周围的凹槽（17），在凹槽中有一个密封圈（18）。槽的轴向宽度为密封环的轴向厚度的1.1倍以上。当安装件被推入吸头时，尖端的内壁可以将密封环向上移动到槽中。尽管不同的尖端和安装件之间存在固有的尺寸差异，但该结构可以提供可靠的密封。

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