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    • 3. 发明授权
    • Cell fragility testing method and appliance therefor
    • 细胞脆性检测方法及其设备
    • US4178152A
    • 1979-12-11
    • US880159
    • 1978-02-22
    • Yoshiaki Nunogaki
    • Yoshiaki Nunogaki
    • G01N33/50G01N33/16
    • G01N33/50Y10T436/25375
    • A method of and an appliance for use in testing the osmotic fragility of blood cells by the use of the CPC method involving a coil column containing an aqueous solution of a salt mixed with one or both of a viscosity modifier and a hemolysis promotor. This coil column, after the blood to be tested has been injected, is centrifuged while undergoing a planetary motion to cause the blood cells to undergo hemolysis. After this hemolysis, a hematological pattern is developed in the coil column, the position of the coil column at which such hematological pattern has been developed being indicative of the osmotic fragility of the subject blood.
    • 一种用于通过使用包含与粘度调节剂和溶血促进剂中的一种或两者混合的盐的水溶液的线圈柱的CPC法来测试血细胞的渗透脆性的方法和器具。 待测血液注射后,将该血管柱离心分离,同时进行行星运动,使血细胞发生溶血。 在这种溶血之后,在线圈柱中形成血液图案,已经开发了这种血液图案的线圈柱的位置指示了主体血液的渗透脆性。
    • 4. 发明授权
    • Centrifugal counter-current distribution chromatography
    • 离心逆流分布色谱法
    • US4968428A
    • 1990-11-06
    • US400054
    • 1989-08-29
    • Yoshiaki Nunogaki
    • Yoshiaki Nunogaki
    • G01N30/42
    • G01N30/42B01D15/1892
    • A cassette for use in a centrifugal counter-current distribution chromatographic apparatus which comprises a motor-driven rotor supported for rotation about a shaft having at least one pocket defined therein, and at least one cassette having a tortuous separation passage defined therein with the opposite ends adapted to be connected respectively to a source of fluid samples and the outside, the fluid samples being continuously supplied to the separation passage while the rotor is driven in one direction at high speed to effect the counter-current distribution. The cassette comprises at least one flat plate member having defined therein a plurality of slots and a corresponding number of narrow grooves alternating with the slots, each of the narrow grooves being continued at one end to one slot and at the other end to the next adjacent slot, sealing plates disposed on respective side faces of the flat plate member, and metallic side plates clamped together with the flat plate member and the sealing plates disposed therebetween. The slots and narrow grooves are so defined in the flat plate member that, when the cassette is mounted on the rotor, they can be oriented radially of the rotor.
    • 一种用于离心逆流分布色谱装置的盒子,包括一个电机驱动的转子,该转子被支承为围绕一轴转动,该转轴具有限定在其中的至少一个凹槽,以及至少一个具有曲折分离通道的盒, 适于分别连接到流体样品源和外部,流体样品被连续地供给到分离通道,同时转子以高速一个方向驱动以实现逆流分布。 盒包括至少一个平板部件,其中限定有多个槽和相应数量的与槽交替的窄槽,每个窄槽在一端连续到一个槽,另一端连续到下一个相邻 狭槽,设置在平板构件的相应侧面上的密封板以及与平板构件夹持在一起的金属侧板和设置在其间的密封板。 狭槽和窄槽在平板构件中被限定,当盒安装在转子上时,它们可以被定向在转子的径向上。
    • 6. 发明授权
    • Centrifugal counter-current distribution chromatography
    • 离心逆流分布色谱法
    • US4877523A
    • 1989-10-31
    • US326498
    • 1989-03-20
    • Yoshiaki Nunogaki
    • Yoshiaki Nunogaki
    • G01N30/42
    • G01N30/42
    • A cassette for use in a centrifugal counter-current distribution chromatographic apparatus which comprises a motor-driven rotor supported for rotation about a shaft having at least one pocket defined therein, and at least one cassette having a tortuous separation passage defined therein with the opposite ends adapted to be connected respectively to a source of fluid samples and the outside, the fluid samles being continuously supplied to the separation passage while the rotor is driven in one direction at high speed to effect the counter-current distribution. The cassette comprises at least one flat plate member having defined therein a plurality of slots and a corresponding number of narrow grooves alternating with the slots, each of the narrow grooves being continued at one end to one slot and at the other end to the next adjacent slot, sealing plates disposed on respective side faces of the flat plate member, and metallic side plates clamped together with the flat plate member and the sealing plates disposed therebetween. The slots and narrow grooves are so defined in the flat plate member that, when the cassette is mounted on the rotor, they can be oriented radially of the rotor.
    • 一种用于离心逆流分布色谱装置的盒子,包括一个电机驱动的转子,该转子被支承为围绕一轴转动,该转轴具有限定在其中的至少一个凹槽,以及至少一个具有曲折分离通道的盒, 适于分别连接到流体样品源和外部,流体样品被连续地供给到分离通道,同时转子以高速一个方向驱动以实现逆流分布。 盒包括至少一个平板部件,其中限定有多个槽和相应数量的与槽交替的窄槽,每个窄槽在一端连续到一个槽,另一端连续到下一个相邻 狭槽,设置在平板构件的相应侧面上的密封板以及与平板构件夹持在一起的金属侧板和设置在其间的密封板。 狭槽和窄槽在平板构件中被限定,当盒安装在转子上时,它们可以被定向在转子的径向上。