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1. 发明授权

US06033357A Intravascular radiation delivery device 失效
公开(公告)号：US06033357A
公开(公告)日：2000-03-07
申请号：US827489
申请日：1997-03-28
申请人： Jay P. Ciezki , Eugene J. Jung, Jr.
发明人： Jay P. Ciezki , Eugene J. Jung, Jr.
IPC分类号： A61M25/00 , A61M25/01 , A61M36/04 , A61M36/12 , A61N5/10
CPC分类号： A61N5/1002 , A61N2005/1005
摘要： A delivery device and method for delivering a dosage of radiation from a radiation source to a treatment site of a vessel is provided herein. The delivery device includes a catheter and a delivery area. The catheter is suitable for being inserted into a vessel lumen of the vessel and includes a delivery lumen for receiving the radiation source. The delivery area also receives the radiation source. The delivery area includes an attenuator section for attenuating a portion of the radiation emitting from the radioactive area so that the delivery area emits an eccentric radiation profile. The delivery device can also include a catheter supporter which inhibits rotational deformation in the catheter between a catheter distal end and a catheter proximal end. This allows the delivery area to be precisely rotated to properly position the attenuator section within the vessel lumen.

2. 发明授权

US5645789A Distensible pet balloon and method of manufacture 失效
标题翻译：可扩张的宠物气球和制造方法
公开(公告)号：US5645789A
公开(公告)日：1997-07-08
申请号：US504537
申请日：1995-07-20
申请人： Leo R. Roucher, Jr.
发明人： Leo R. Roucher, Jr.
IPC分类号： A61F2/958 , A61L29/00 , A61M25/00 , B29C49/00 , B29C49/08 , B29C49/18
CPC分类号： A61M25/1029 , A61M25/10 , B29C49/0042 , B29C49/08 , B29C49/18 , B29C2049/0089 , B29K2067/00 , B29K2105/258 , Y10S264/905
摘要： A semi-compliant PET balloon and a method for manufacturing the balloon are disclosed. The method for manufacturing the semi-compliant PET balloon includes the steps of varying the temperature and inflation pressure on a tube of PET material in an ordered sequence to i) form the balloon, ii) thin the walls of the balloon, ii) size the balloon and then, iv) crystallize the PET material of the balloon. First, to form the balloon, the tube of PET material is preheated, and simultaneously pressurized and stretched. The pressure in the tube is then increased to conform the balloon to the shape of a mold. Next the balloon walls are thinned by decreasing pressure and providing additional stretch on the PET tube. A subsequent increase in pressure sizes the balloon. The sized balloon is next subjected to an increase in temperature and a decrease in pressure to crystallize the PET material. A cooling step completes the method for manufacture.
摘要翻译：公开了一种半顺应性PET球囊及其制造方法。用于制造半顺应性PET球囊的方法包括以有序的顺序改变PET材料管上的温度和充气压力的步骤，以便i）形成球囊，ii）使气球的壁变细，ii）气球，然后iv）使气囊的PET材料结晶。首先，为了形成气囊，将PET材料管预热，同时加压拉伸。然后增加管中的压力以使气囊符合模具的形状。接下来，气球壁通过减小压力而变薄，并在PET管上提供额外的拉伸。随后压力的增加使气球尺寸增大。接着，将尺寸的气囊经受温度升高和压力降低以使PET材料结晶。冷却步骤完成了制造方法。

3. 发明授权

US5876419A Stent and method for making a stent 失效
标题翻译：支架和支架制作方法
公开(公告)号：US5876419A
公开(公告)日：1999-03-02
申请号：US950969
申请日：1997-10-15
申请人： Kenneth W. Carpenter , Leo R. Roucher, Jr. , Eugene J. Jung, Jr. , Erich H. Wolf , Thomas A. Steinke , Robert J. Duffy , Philip L. Baddour
发明人： Kenneth W. Carpenter , Leo R. Roucher, Jr. , Eugene J. Jung, Jr. , Erich H. Wolf , Thomas A. Steinke , Robert J. Duffy , Philip L. Baddour
IPC分类号： A61F2/92 , A61M29/00
CPC分类号： A61F2/915 , A61F2/93 , A61F2/958 , A61F2002/91591
摘要： The present invention is a stent for insertion into an artery or other vessel. The stent is formed from a series of tubular shaped bands each formed with a first end which overlaps a second end. The overlap between the first and second ends is variable and allows each band to move between a contracted configuration and a fully expanded configuration which are within the elastic limits of the band. Each band includes a plurality of receivers and a first tab on a first edge of the band to secure each band at or near the fully expanded configuration and allow the stent to conform to the contours of the vessel. The bands are distributed along a substantially common axis to form a tube interconnected by a pair of elongated strips. In use, the stent is placed over a balloon catheter and compressed to adopt the contracted configuration. The stent may be maintained in the contracted configuration by a retainer. The balloon catheter and stent are then advanced through a placement catheter to a target site where the balloon is partially inflated to free the stent for expansion to an equilibrium configuration. The balloon may then be more fully inflated to further expand any of the bands in the stent to suit the needs of the patient. The balloon is then deflated and removed, leaving the expanded stent to support that target site.
摘要翻译：本发明是用于插入动脉或其他血管的支架。支架由一系列管状带形成，每个管状带形成有与第二端重叠的第一端。第一和第二端之间的重叠是可变的，并且允许每个带在收缩构型和处于该带的弹性极限内的完全展开构型之间移动。每个带包括多个接收器和在带的第一边缘上的第一接头，以将每个带固定在完全展开的构型处或附近，并允许支架符合容器的轮廓。带沿着基本上共同的轴线分布以形成通过一对细长带相互连接的管。在使用中，将支架放置在气囊导管上并压缩以采用收缩构造。支架可以通过保持器保持在收缩构造中。气球导管和支架然后通过放置导管前进到目标部位，其中气囊被部分充气以释放支架用于扩张至平衡构型。然后，气球可以被更充分地充气以进一步扩张支架中的任何带以满足患者的需要。然后将气囊放气并除去，留下扩张的支架以支持该靶位点。

4. 发明授权

US5735872A Stent 失效
标题翻译：支架
公开(公告)号：US5735872A
公开(公告)日：1998-04-07
申请号：US720714
申请日：1996-10-02
申请人： Kenneth W. Carpenter , Leo R. Roucher, Jr. , Eugene J. Jung, Jr. , Erich H. Wolf , Thomas A. Steinke
发明人： Kenneth W. Carpenter , Leo R. Roucher, Jr. , Eugene J. Jung, Jr. , Erich H. Wolf , Thomas A. Steinke
IPC分类号： A61F2/82 , A61F2/92 , A61M29/00
CPC分类号： A61F2/93 , A61F2/958
摘要： The present invention is a stent for insertion into an artery or other vessel. The stent is formed from a series of tubular shaped bands each formed with a first end which overlaps a second end. The overlap between the first and second ends is variable and allows each band to move between a contracted configuration and a fully expanded configuration which are within the elastic limits of the band. Each band includes a plurality of receivers and a first tab on a first edge of the band to secure each band at or near the fully expanded configuration and allow the stent to conform to the contours of the vessel. The bands are distributed along a substantially common axis to form a tube interconnected by a pair of elongated strips. In use, the stent is placed over a balloon catheter and compressed to adopt the contracted configuration. The stent is maintained in the contracted configuration by a retainer. The balloon catheter and stent are then advanced through a placement catheter to a target site where the balloon is partially inflated to free the stent for expansion to an equilibrium configuration. The balloon may then be more fully inflated to further expand any of the bands in the stent to suit the needs of the patient. The balloon is then deflated and removed, leaving the expanded stent to support that target site.
摘要翻译：本发明是用于插入动脉或其他血管的支架。支架由一系列管状带形成，每个管状带形成有与第二端重叠的第一端。第一和第二端之间的重叠是可变的，并且允许每个带在收缩构型和处于该带的弹性极限内的完全展开构型之间移动。每个带包括多个接收器和在带的第一边缘上的第一接头，以将每个带固定在完全展开的构型处或附近，并允许支架符合容器的轮廓。带沿着基本上共同的轴线分布以形成通过一对细长带相互连接的管。在使用中，将支架放置在气囊导管上并压缩以采用收缩构造。支架通过保持器保持在收缩构型中。气球导管和支架然后通过放置导管前进到目标部位，其中气囊被部分充气以释放支架用于扩张至平衡构型。然后，气球可以被更充分地充气以进一步扩张支架中的任何带以满足患者的需要。然后将气囊放气并除去，留下扩张的支架以支持该靶位点。

5. 发明授权

US6077213A Intravascular radiation delivery device 失效
公开(公告)号：US6077213A
公开(公告)日：2000-06-20
申请号：US114594
申请日：1998-07-13
申请人： Jay P. Ciezki , Eugene J. Jung, Jr.
发明人： Jay P. Ciezki , Eugene J. Jung, Jr.
IPC分类号： A61M25/00 , A61M25/01 , A61M36/04 , A61M36/12 , A61N5/10 , A61N5/00
CPC分类号： A61N5/1002 , A61N2005/1005
摘要： A delivery device and method for delivering a dosage of radiation from a radiation source to a treatment site of a vessel is provided herein. The delivery device includes a catheter and a delivery area. The catheter is suitable for being inserted into a vessel lumen of the vessel and includes a delivery lumen for receiving the radiation source. The delivery area also receives the radiation source. The delivery area includes an attenuator section for attenuating a portion of the radiation emitting from the radioactive area so that the delivery area emits an eccentric radiation profile. The delivery device can also include a catheter supporter which inhibits rotational deformation in the catheter between a catheter distal end and a catheter proximal end. This allows the delivery area to be precisely rotated to properly position the attenuator section within the vessel lumen.

6. 发明授权

US5643314A Self-expanding stent 失效
标题翻译：自扩张支架
公开(公告)号：US5643314A
公开(公告)日：1997-07-01
申请号：US557725
申请日：1995-11-13
申请人： Kenneth W. Carpenter , Leo R. Roucher, Jr. , Eugene J. Jung, Jr.
发明人： Kenneth W. Carpenter , Leo R. Roucher, Jr. , Eugene J. Jung, Jr.
IPC分类号： A61F2/82 , A61F2/92 , A61M29/00
CPC分类号： A61F2/82 , A61F2/92 , A61F2/958
摘要： The present invention provides a self-expanding stent for insertion into an artery or other internal vessel. The stent is formed from a series of radial bands each formed with overlapping first and second ends. The overlap between the first and second ends is variable, allowing each band to move between a contracted configuration and an expanded configuration. The first and second ends of each band are both formed to include a tab which is folded to hold the first and second end against the band. The bands are distributed along a common axis to form a cylinder and interconnected by a pair of elongated strips. In use, the stent is placed over a balloon catheter and compressed to adopt the contracted configuration. The balloon catheter and stent are then advanced through a placement catheter and to a target site where the balloon is partially inflated to free the stent for self-expansion. The balloon may then be more fully inflated to further expand any of the radial bands in the stent. The balloon is then deflated and removed, leaving the expanded stent to support that target site.
摘要翻译：本发明提供一种用于插入动脉或其他内部血管的自扩张支架。支架由一系列径向带形成，每个径向带形成有重叠的第一和第二端。第一和第二端之间的重叠是可变的，允许每个带在收缩配置和扩展配置之间移动。每个带的第一和第二端都形成为包括折叠片，以将第一和第二端保持抵靠带。带沿着公共轴线分布以形成圆柱体并且通过一对细长条带互连。在使用中，将支架放置在气囊导管上并压缩以采用收缩构造。气囊导管和支架然后通过放置导管前进到靶部位，其中气囊被部分充气以释放支架以进行自我扩张。然后可以使球囊充分充气以进一步扩张支架中的任何径向带。然后将气囊放气并除去，留下扩张的支架以支持该靶位点。

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