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1. 发明申请

US20230122509A1 METHOD FOR ANALYZING GLYCOSAMINOGLYCAN 有权
公开(公告)号：US20230122509A1
公开(公告)日：2023-04-20
申请号：US17501387
申请日：2021-10-14
申请人： SHIMADZU CORPORATION , NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
发明人： Takanari HATTORI , Jun WATANABE , Tetsuo IIDA , Misa TANAKA , Hironori KOBAYASHI , Shunji TOMATSU
IPC分类号： G01N33/50 , G01N30/72
摘要： Provided is a method by which the disaccharides derived from glycosaminoglycans can be analyzed in a stable and highly reproduceable manner. A method for analyzing a glycosaminoglycan according to the present invention includes: a first process for producing a plurality of kinds of disaccharides derived from a glycosaminoglycan in a biological sample by adding a plurality of kinds of glycosaminoglycan-specific enzymes to the biological sample: and a second process for separating and analyzing the plurality of kinds of disaccharides by a liquid chromatography-mass spectrometry method, where a column used for liquid chromatography in the liquid chromatography-mass spectrometry method is a column packed with a stationary-phase support to which an amide group as a functional group is bound, or a column packed with a stationary-phase support to which an adamantyl group as a functional group is bound.

2. 发明申请

US20210132074A1 DIAGNOSTIC DRUG, DIAGNOSTIC METHOD AND DIAGNOSTIC DEVICE FOR PERMEABILITY OF INTESTINAL MUCOSA 有权
公开(公告)号：US20210132074A1
公开(公告)日：2021-05-06
申请号：US16478421
申请日：2018-01-17
申请人： National University Corporation Shimane University , KOYO CHEMICAL CO., LTD.
发明人： Koichiro WADA , Haruki USUDA , Morihiko NAKAMURA , Yoshimori TAKAMORI , Seiji KUROZUMI
IPC分类号： G01N33/66 , A61K49/00 , A61K9/00 , G01N33/50
摘要： Provided is a diagnostic drug for evaluating permeability of intestinal mucosa, including chitin and/or chitosan as a main component. The chitin and/or chitosan to be used preferably has a weight average molecular weight prepared to a range of from 1,000 to 11,600.

3. 发明授权

US09266106B2 Micro-channel chip 有权
标题翻译：微通道芯片
公开(公告)号：US09266106B2
公开(公告)日：2016-02-23
申请号：US14380602
申请日：2013-02-25
申请人： National University Corporation Shimane University
发明人： Yasuhisa Fujita , Haruo Takeshita , Junko Fujihara , Yutaka Fukui , Mari Tabuchi
IPC分类号： G01N27/453 , B01L3/00 , G01N21/05 , G01N21/64 , G01N27/447 , G01N21/03
CPC分类号： B01L3/502715 , B01L3/5027 , B01L2400/0415 , G01N21/05 , G01N21/643 , G01N21/645 , G01N21/6486 , G01N27/44704 , G01N27/44791 , G01N2021/0346 , G01N2021/058 , G01N2021/6482 , G01N2201/061
摘要： A convenient technique allows detecting fluorescence emitted in the channel with a uniformly high detection sensitivity and a good reproducibility. On the front face side of a plate-like body 11, a groove-shaped introduction channel 12 and separation channel 14 are formed. In this micro-channel chip 10, on the inner faces of a groove constituting the separation channel 14 formed in a surface of the plate-like body 11, there is formed a fine particle layer 20 provided by sintering fine particles having an average particle diameter of 10 to 500 nm mainly composed of zinc oxide (ZnO) or titanium oxide (TiO2).
摘要翻译：方便的技术允许以均匀高的检测灵敏度和良好的再现性检测在通道中发射的荧光。在板状体11的正面侧，形成有槽状的导入槽12和分离槽14。在该微通道芯片10中，在形成在板状体11的表面上的构成分离通道14的槽的内表面上形成微粒层20，其通过烧结平均粒径主要由氧化锌（ZnO）或氧化钛（TiO2）组成的10〜500nm。

4. 发明授权

US08388669B2 Hair growth modulating method and modulation device thereof 有权
标题翻译：毛发生长调节方法及其调制装置
公开(公告)号：US08388669B2
公开(公告)日：2013-03-05
申请号：US12593604
申请日：2007-12-25
申请人： Chosei Hamada , Masato Kinoshita , Takashi Matsuzaki , Toshitatsu Nogita
发明人： Chosei Hamada , Masato Kinoshita , Takashi Matsuzaki , Toshitatsu Nogita
IPC分类号： A61N5/06 , A61B19/00 , A61B18/18
CPC分类号： A61N5/0617 , A61B18/203 , A61B2018/00452 , A61B2018/00476 , A61N5/062
摘要： A modulating light having a wavelength of 400 nm to 600 nm is irradiated to a portion around hair roots at an energy of 0.01 J/cm2 to 1 J/cm2 over a time period of not more than 1 ms as a flash light such that a light absorptive component existing in a human body around the hair roots absorbs the light for modulating hair growth without causing substantial adverse effect.
摘要翻译：以0.01J / cm 2〜1J / cm 2的能量，以不大于1ms的时间作为闪光照射发光根部周围的部分的波长为400nm〜600nm的调制光，存在于发根周围的人体中的光吸收成分吸收光，用于调节毛发生长而不引起实质的不利影响。

5. 发明申请

US20190226941A1 MEASUREMENT METHOD, MEASUREMENT DEVICE, AND NON-TRANSITORY RECORDING MEDIUM 审中-公开
公开(公告)号：US20190226941A1
公开(公告)日：2019-07-25
申请号：US16329130
申请日：2017-05-01
申请人： FUJIKURA LTD. , NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
发明人： Ryo Maruyama , Nobuo Kuwaki , Fumihiko Ito
IPC分类号： G01M11/00
摘要： A measurement method for measuring an effective refractive index difference between two propagation modes of a multimode fiber is provided. The method includes: measuring a first Brillouin frequency shift v1 by specifying a frequency having a lowest-frequency peak out of peaks in a first frequency spectrum of scattered light in a first propagation mode; measuring a second Brillouin frequency shift v2 by specifying a frequency having a lowest-frequency peak out of peaks in a second frequency spectrum of scattered light in a second propagation mode; and calculating an effective refractive index difference Δneff in accordance with Δneff=(v1−v2)/(2kVL) with use of the first Brillouin frequency shift v1, the second Brillouin frequency shift v2, a predetermined wave number k of light in a vacuum, and a predetermined constant VL.

6. 发明申请

US20170131175A1 PIPE EVALUATION METHOD, MEASUREMENT DEVICE, AND PIPE EVALUATION SYSTEM 审中-公开
公开(公告)号：US20170131175A1
公开(公告)日：2017-05-11
申请号：US15414965
申请日：2017-01-25
申请人： NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY , NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
发明人： Masahiro Hyodo , Hidehiko Ogata , Naoki Kawamura , Tsuguhiro Nonaka , Masayuki Ishii
IPC分类号： G01M5/00 , G01N3/08
摘要： This internal pressure loading system includes an internal pressure loading device and an information processing device. The internal pressure loading device is set at an inner face of a pipe, and includes a load meter which detects the load applied to the inner face of the pipe and a displacement meter which detects the deformation amount of the pipe. When the internal pressure loading device is expanded so as to increase the load to be detected by the load meter, the width of the pipe at which the displacement meter is located is reduced. On the basis of the load detected by the load meter and the deformation amount detected by the displacement meter, the information processing device evaluates the remaining strength of the pipe.

7. 发明申请

US20150318659A1 AMPLIFYING OPTICAL FIBER AND OPTICAL AMPLIFIER 有权
标题翻译：放大光纤和光放大器
公开(公告)号：US20150318659A1
公开(公告)日：2015-11-05
申请号：US14440984
申请日：2013-10-31
申请人： FUJIKURA LTD. , NIPPON TELEGRAPH AND TELEPHONE CORPORATION , OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION , National University Corporation Shimane University
发明人： Shoichiro Matsuo , Katsuhiro Takenaga , Kentaro Ichii , Hirotaka Ono , Kyouzou Tsujikawa , Makoto Yamada , Hiroji Masuda
IPC分类号： H01S3/067 , G02B6/02 , G02B6/036
CPC分类号： H01S3/06737 , G02B6/02042 , G02B6/036 , G02B6/03633 , G02B6/04 , H01S3/06733 , H01S3/06754 , H01S3/094007 , H01S3/2383
摘要： A plurality of cores 51 is disposed around the center axis of a first cladding 52 in a state in which an inter-core distance Λ of cores adjacent to each other is equal, a refractive index n1 of the core 51 is provided higher than a refractive index n2 of the first cladding 52, and the refractive index n2 of the first cladding 52 is provided higher than a refractive index n3 of a second cladding 53. Moreover, 5.8≦Λ/MFD(2λc/(λc+λop))≦8 is satisfied, where the inter-core distance is defined as Λ, a mode field diameter of the core is defined as MFD, a cutoff wavelength is defined as λc, and a wavelength of communication light incident on the core 51 is defined as λop.
摘要翻译：在彼此相邻的芯的芯间距离Λ相等的状态下，多个芯51围绕第一包层52的中心轴设置，芯51的折射率n1被设置为高于折射率第一包层52的折射率n2和第一包层52的折射率n2被设置为高于第二包层53的折射率n3。此外，5.8＆nlE;Λ/ MFD（2λc/（λc+λop））＆nlE 8，其中芯间距离被定义为Λ，芯的模场直径被定义为MFD，截止波长被定义为λc，并且入射在芯51上的通信光的波长被定义为 λop。

8. 发明申请

US20150070942A1 DC-DC CONVERTER 审中-公开
标题翻译： DC-DC转换器
公开(公告)号：US20150070942A1
公开(公告)日：2015-03-12
申请号：US14385322
申请日：2013-01-24
申请人： Sanken Electric Co., Ltd. , National University Corporation Shimane University
发明人： Hiromitsu Terui , Hideki Asuke , Hideharu Takano , Masayoshi Yamamoto , Jun Imaoka
IPC分类号： H02M3/335
摘要： A DC-DC converter includes a coupling transformer that has windings 11 and 12, switches (Tr1, Tr2) that are connected through the windings to both ends of a DC power source Vi, a series circuit that is connected to both ends of each of the switches and includes a diode and a smoothing capacitor, and a controller 100 that alternately turns on the switches Tr1 and Tr2 and simultaneously turns on the switches Tr1 and Tr2 for a predetermined overlapping period on every half cycle. The coupling transformer 1 includes an I-shaped core 4, two E-shaped cores 2 and 3 holding the I-shaped core 4 between them, and a gap 5 formed between each of center legs 2a and 3a of the E-shaped cores 2 and 3 and the I-shaped core 4. The windings 11 and 12 are wound around the I-shaped core 4.
摘要翻译： DC-DC转换器包括具有绕组11和12的耦合变压器，通过绕组连接到直流电源Vi两端的开关（Tr1，Tr2），连接到每个的两端的串联电路开关并包括二极管和平滑电容器，以及控制器100，其交替地接通开关Tr1和Tr2，并且在每半个周期同时使开关Tr1和Tr2导通预定的重叠周期。耦合变压器1包括I形磁芯4，在它们之间保持I形磁芯4的两个E形磁芯2和3以及在E形磁芯2的每个中心支腿2a和3a之间形成的间隙5 绕组11和12缠绕在I形芯4上。

9. 发明授权

US08368364B2 DC-DC converter with snubber circuit 有权
标题翻译：具有缓冲电路的DC-DC转换器
公开(公告)号：US08368364B2
公开(公告)日：2013-02-05
申请号：US12999932
申请日：2009-06-15
申请人： Hideki Asuke , Hideharu Takano , Mamoru Tsuruya , Masayoshi Yamamoto , Takahiro Kawashima , Shigeyuki Funabiki
发明人： Hideki Asuke , Hideharu Takano , Mamoru Tsuruya , Masayoshi Yamamoto , Takahiro Kawashima , Shigeyuki Funabiki
IPC分类号： G05F1/613 , G05F1/24
CPC分类号： H02M3/1584 , H02M1/34 , H02M2001/348
摘要： In order to achieve an object to reduce a surge voltage and suppress noise generation, the present invention provides a DC-DC converter with a snubber circuit, which boosts a voltage Vi of a DC power supply. The snubber circuit includes: a series circuit connected to both ends of a smoothing capacitor Co and including a snubber capacitor Cs and a snubber resistor Rs; a snubber diode Ds1 connected to a node at which the snubber capacitor Cs and the snubber resistor Rs are connected, and to a node at which a reactor Lr1 and an additional winding 1b of a transformer T1 are connected; and a snubber diode Ds2 connected to the node at which the snubber capacitor Cs and the snubber resistor Rs are connected, and to a node at which a reactor Lr2 and an additional winding 2b of a transformer T2 are connected.
摘要翻译：为了实现降低浪涌电压并抑制噪声产生的目的，本发明提供一种具有缓冲电路的DC-DC转换器，其提高DC电源的电压Vi。缓冲电路包括：连接到平滑电容器Co的两端并包括缓冲电容器Cs和缓冲电阻器Rs的串联电路; 连接到缓冲电容器Cs和缓冲电阻器Rs连接的节点的缓冲二极管Ds1以及与变压器T1的电抗器Lr1和附加绕组1b连接的节点; 以及连接到缓冲电容器Cs和缓冲电阻器Rs所连接的节点的缓冲二极管Ds2以及与变压器T2的电抗器Lr2和附加绕组2b连接的节点。

10. 发明申请

US20110051474A1 RESONANT POWER CONVERSION APPARATUS 有权
标题翻译：谐振电源转换装置
公开(公告)号：US20110051474A1
公开(公告)日：2011-03-03
申请号：US12861327
申请日：2010-08-23
申请人： Hiromitsu TERUI , Hideki Asuke , Hideharu Takano , Masayoshi Yamamoto
发明人： Hiromitsu TERUI , Hideki Asuke , Hideharu Takano , Masayoshi Yamamoto
IPC分类号： H02M5/45
CPC分类号： H02M1/34 , H02M7/4826 , H02M2007/4811
摘要： A resonant power conversion apparatus includes a transformer T1 having a primary winding n1, a secondary winding n2, a tertiary winding n3, and a reset winding nR, a series circuit of switches S1 and S2, a capacitor Cr1 and diode D1 to the switch S1, a capacitor Cr2 and diode D2 to the switch S2, a series circuit of the winding n1 and a diode Dn1, a series circuit of the winding nR and a diode DR, a reactor Lr connected between a connection point of the switches S1 and S2 and a connection point of the windings n2 and n3, a switch S10 connected between the DC power source and the winding n2, a switch S20 connected between the DC power source and the winding n3, and a controller 10 configured to perform a zero-voltage switching operation of the switches S1 and S2.
摘要翻译：谐振功率转换装置包括具有初级绕组n1，次级绕组n2，第三绕组n3和复位绕组nR的变压器T1，开关S1和S2的串联电路，电容器Cr1和二极管D1到开关S1 ，开关S2的电容器Cr2和二极管D2，绕组n1和二极管Dn1的串联电路，绕组nR和二极管DR的串联电路，连接在开关S1和S2的连接点之间的电抗器Lr 和绕组n2和n3的连接点，连接在直流电源和绕组n2之间的开关S10，连接在直流电源和绕组n3之间的开关S20，以及被配置为执行零电压开关S1和S2的切换操作。

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