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1. 发明授权

US09006685B2 Device and method for determining the concentration of fluorophores in a sample 有权
标题翻译：用于测定样品中荧光团浓度的装置和方法
公开(公告)号：US09006685B2
公开(公告)日：2015-04-14
申请号：US13444027
申请日：2012-04-11
申请人： Rafael Egger , Jörg Zeiner
发明人： Rafael Egger , Jörg Zeiner
IPC分类号： G01J1/58 , G01N21/64 , G01N21/27
CPC分类号： G01N21/645 , G01N21/278 , G01N2201/06113 , G01N2201/062 , G01N2201/068
摘要： A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (λex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (λex1), have a first excitation efficiency and, given an immission of light of a second wavelength (λex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.
摘要翻译：用于分析含有荧光团的样品（16）的装置（10）和方法使用在样品（16）上发射光（λex）的光源（12）和荧光标准品（14）。给定发射第一波长（λex1）的光的样品（16）的荧光团具有第一激发效率，并且在给出第二波长（λex2）的光的情况下，具有第二激发效率。给予相同光量的荧光标准（14）具有第三激发效率和第四激发效率。布置在光源（12）和样品（16）和/或（12）荧光标准品（14）之间的光学元件（20）由于其光学特性而适应第一激发效率第二激励效率和第三励磁效率与第四励磁效率之间的第二差。

2. 发明申请

US20120261591A1 DEVICE AND METHOD FOR DETERMINING THE CONCENTRATION OF FLUOROPHORES IN A SAMPLE 有权
标题翻译：用于测定样品中荧光素浓度的装置和方法
公开(公告)号：US20120261591A1
公开(公告)日：2012-10-18
申请号：US13444027
申请日：2012-04-11
申请人： Rafael Egger , Jörg Zeiner
发明人： Rafael Egger , Jörg Zeiner
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01N21/278 , G01N2201/06113 , G01N2201/062 , G01N2201/068
摘要： A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (λex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (λex1), have a first excitation efficiency and, given an immission of light of a second wavelength (λex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.
摘要翻译：用于分析含有荧光团的样品（16）的装置（10）和方法使用在样品（16）上发射光（λex）的光源（12）和荧光标准品（14）。给定发射第一波长（λex1）的光的样品（16）的荧光团具有第一激发效率，并且在给出第二波长（λex2）的光的情况下，具有第二激发效率。给予相同光量的荧光标准（14）具有第三激发效率和第四激发效率。布置在光源（12）和样品（16）和/或（12）荧光标准品（14）之间的光学元件（20）由于其光学特性而适应第一激发效率第二激励效率和第三励磁效率与第四励磁效率之间的第二差。

3. 发明申请

US20090323070A1 METHOD AND APPARATUS FOR DETERMINING THE CONCENTRATION OF A SUBSTANCE IN A LIQUID 有权
标题翻译：用于测定液体中物质浓度的方法和装置
公开(公告)号：US20090323070A1
公开(公告)日：2009-12-31
申请号：US12487912
申请日：2009-06-19
申请人： Rafael Egger
发明人： Rafael Egger
IPC分类号： G01N21/55
CPC分类号： G01N21/8483 , G01N21/314
摘要： In a method for determining the concentration of at least one substance in a liquid the liquid is applied onto a test strip containing at least one test zone, wherein an optical sensor arrangement is moved step-by-step in a first direction over the surface of the test strip while the test trip is at the same time irradiated with light of a predetermined wave length and wherein in each step the radiation reflected from the surface of the test strip is measured, and wherein in each measurement step the test strip surface is irradiated alternately with light of at least two different wave lengths and the irradiation is measured at the same time and the difference between the measurement signals obtained in each measurement step using irradiation light of different wave lengths is analyzed.
摘要翻译：在用于确定液体中至少一种物质的浓度的方法中，将液体施加到含有至少一个测试区域的测试条上，其中光学传感器装置在第一方向上逐步移动到测试条同时用预定波长的光照射，并且其中在每个步骤中测量从测试条表面反射的辐射，并且其中在每个测量步骤中辐射测试条表面交替地具有至少两个不同波长的光，并且同时测量照射，并且分析使用不同波长的照射光在每个测量步骤中获得的测量信号之间的差。

4. 发明授权

US08334522B2 Method for the quantitative determination of the concentration of fluorophores of a substance in a sample and apparatus for carrying out the same 有权
标题翻译：用于定量测定样品中物质的荧光团的浓度的方法和用于进行该物质的装置的方法
公开(公告)号：US08334522B2
公开(公告)日：2012-12-18
申请号：US12616811
申请日：2009-11-12
申请人： Rafael Egger
发明人： Rafael Egger
IPC分类号： F21V9/16 , G01J1/58 , G01T1/10 , G21H3/02 , G21K5/00 , H01J65/06 , H01J65/08
CPC分类号： G01N21/278 , G01N21/6428
摘要： The invention concerns methods and apparatuses for quantitatively determining the concentration of fluorophores of a substance in a sample. A constant portion of the reference light of a reference light wave length (λr) emitted by a reference light source is coupled in by an optical element in the direction of a receiving element. A first value corresponding to the portion of the reference light coupled in which is incident on the receiving element is detected. The sample is irradiated with the excitation light of an excitation wave length (λex) emitted by an excitation light source. A second value corresponding to the portion of the fluorescent light of an emission wave length (λem) emitted by the sample which is incident on the receiving element. The ratio of the second value to the first value is determined. The number of fluorophores in the substance is determined based on the ratio.
摘要翻译：本发明涉及用于定量测定样品中物质的荧光团浓度的方法和装置。由参考光源发射的参考光波长（λr）的参考光的恒定部分通过光学元件沿接收元件的方向耦合。检测对应于其中入射在接收元件上的参考光的部分的第一值。用激发光源发射的激发波长（λex）的激发光照射样品。对应于由入射在接收元件上的样品发射的发射波长（λem）的荧光的部分的第二值。确定第二值与第一值的比率。该物质中荧光团的数量是根据比例来确定的。

5. 发明授权

US07507371B2 Method for disinfecting a cuvette cover 失效
标题翻译：消毒试管盖的方法
公开(公告)号：US07507371B2
公开(公告)日：2009-03-24
申请号：US11135872
申请日：2005-05-24
申请人： Klaus Deuter
发明人： Klaus Deuter
IPC分类号： A61L2/04
CPC分类号： A61L2/04
摘要： The invention concerns a method and an apparatus for disinfecting a cuvette cover. The opening of a cuvette (14) containing a test fluid is temporarily covered while the cuvette is at a processing station. The surface of the cover facing the cuvette opening in the lifted condition of the cover is heated to a temperature suitable for the killing of microorganisms on the cover.
摘要翻译：本发明涉及一种用于消毒比色杯盖的方法和装置。在比色皿处于加工站时，容纳测试流体的比色皿（14）的开口被暂时覆盖。在盖的提升状态下面向比色皿开口的盖的表面被加热到适于杀死盖上的微生物的温度。

6. 发明授权

US07431885B2 Measuring device for the amperometric measurement of test strips 有权
标题翻译：测试条的电流测量用测量装置
公开(公告)号：US07431885B2
公开(公告)日：2008-10-07
申请号：US11752347
申请日：2007-05-23
申请人： Norbert Pöllmann , Wolfgang Heider , Genrich Siris
发明人： Norbert Pöllmann , Wolfgang Heider , Genrich Siris
IPC分类号： G01N21/00
CPC分类号： G01N27/404 , Y10T436/144444
摘要： A measuring device for the amperometric measurement of test strips 12, each having a test field moistenable by a liquid to be investigated and having measuring electrodes associated with the test field. The device includes at least one test strip receiver 20 for the insertion of a test strip 12, first contact elements arranged in the region of the strip receiver 20 for contacting the measuring electrodes of a test strip 12 located in the strip receiver 20, and an evaluation and control circuit. The strip receiver 20 is formed with a separate unitary housing which on its external side has second external contact elements 50 electrically connected with the first internal contact elements. The external contact elements 50 are designed for contacting opposite contact elements 16 connected with the evaluation and control circuit.
摘要翻译：用于测试条12的电流测量的测量装置，每个测量装置具有可被待研究的液体润湿的测试区域，并且具有与测试场相关联的测量电极。该装置包括用于插入测试条12的至少一个测试条接收器20，布置在带状接收器20的区域中的第一接触元件用于接触位于带状接收器20中的测试条12的测量电极，以及评估和控制电路。带状接收器20形成有单独的单一外壳，其外侧具有与第一内部接触元件电连接的第二外部接触元件50。外部接触元件50被设计用于接触与评估和控制电路连接的相对的接触元件16。

7. 发明申请

US20070274866A1 MEASURING DEVICE FOR THE AMPEROMETRIC MEASUREMENT OF TEST STRIPS 有权
标题翻译：测试仪测量装置的测量装置
公开(公告)号：US20070274866A1
公开(公告)日：2007-11-29
申请号：US11752347
申请日：2007-05-23
申请人： Norbert Pollmann , Wolfgang Heider , Genrich Siris
发明人： Norbert Pollmann , Wolfgang Heider , Genrich Siris
IPC分类号： G01N33/48
CPC分类号： G01N27/404 , Y10T436/144444
摘要： A measuring device for the amperometric measurement of test strips 12, each having a test field moistenable by a liquid to be investigated and having measuring electrodes associated with the test field. The device includes at least one test strip receiver 20 for the insertion of a test strip 12, first contact elements arranged in the region of the strip receiver 20 for contacting the measuring electrodes of a test strip 12 located in the strip receiver 20, and an evaluation and control circuit. The strip receiver 20 is formed with a separate unitary housing which on its external side has second external contact elements 50 electrically connected with the first internal contact elements. The external contact elements 50 are designed for contacting opposite contact elements 16 connected with the evaluation and control circuit.
摘要翻译：用于测试条12的电流测量的测量装置，每个测量装置具有可被待研究的液体润湿的测试区域，并且具有与测试场相关联的测量电极。该装置包括用于插入测试条12的至少一个测试条接收器20，布置在带状接收器20的区域中的第一接触元件用于接触位于带状接收器20中的测试条12的测量电极，以及评估和控制电路。带状接收器20形成有单独的单一外壳，其外侧具有与第一内部接触元件电连接的第二外部接触元件50。外部接触元件50被设计用于接触与评估和控制电路连接的相对的接触元件16。

8. 发明申请

US20050265891A1 Method and apparatus for disinfecting a cuvette cover 失效
标题翻译：消毒试管盖的方法和设备
公开(公告)号：US20050265891A1
公开(公告)日：2005-12-01
申请号：US11135872
申请日：2005-05-24
申请人： Klaus Deuter
发明人： Klaus Deuter
IPC分类号： A61L2/00 , A61L2/04 , C12M1/00 , C12M1/12 , C12M1/34
CPC分类号： A61L2/04
摘要： The invention concerns a method and an apparatus for disinfecting a cuvette cover. The opening of a cuvette (14) containing a test fluid is temporarily covered while the cuvette is at a processing station. The surface of the cover facing the cuvette opening in the lifted condition of the cover is heated to a temperature suitable for the killing of microorganisms on the cover.
摘要翻译：本发明涉及一种用于消毒比色杯盖的方法和装置。在比色皿处于加工站时，容纳测试流体的比色皿（14）的开口被暂时覆盖。在盖的提升状态下面向比色皿开口的盖的表面被加热到适于杀死盖上的微生物的温度。

9. 发明授权

US09335268B2 Device and method for determining the concentration of fluorophores in a sample 有权
公开(公告)号：US09335268B2
公开(公告)日：2016-05-10
申请号：US14607274
申请日：2015-01-28
申请人： LRE Medical GmbH
发明人： Rafael Egger , Jörg Zeiner
IPC分类号： G01N21/64 , G01N21/27
CPC分类号： G01N21/645 , G01N21/278 , G01N2201/06113 , G01N2201/062 , G01N2201/068
摘要： A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (λex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (λex1), have a first excitation efficiency and, given an immission of light of a second wavelength (λex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.

10. 发明授权

US08045172B2 Method and apparatus for determining the concentration of a substance in a liquid 有权
标题翻译：用于确定液体中物质浓度的方法和装置
公开(公告)号：US08045172B2
公开(公告)日：2011-10-25
申请号：US12487912
申请日：2009-06-19
申请人： Rafael Egger
发明人： Rafael Egger
IPC分类号： G01N21/55
CPC分类号： G01N21/8483 , G01N21/314
摘要： In a method for determining the concentration of at least one substance in a liquid the liquid is applied onto a test strip containing at least one test zone, wherein an optical sensor arrangement is moved step-by-step in a first direction over the surface of the test strip while the test trip is at the same time irradiated with light of a predetermined wave length and wherein in each step the radiation reflected from the surface of the test strip is measured, and wherein in each measurement step the test strip surface is irradiated alternately with light of at least two different wave lengths and the irradiation is measured at the same time and the difference between the measurement signals obtained in each measurement step using irradiation light of different wave lengths is analyzed.
摘要翻译：在用于确定液体中至少一种物质的浓度的方法中，将液体施加到含有至少一个测试区域的测试条上，其中光学传感器装置在第一方向上逐步移动到测试条同时用预定波长的光照射，并且其中在每个步骤中测量从测试条表面反射的辐射，并且其中在每个测量步骤中辐射测试条表面交替地具有至少两个不同波长的光，并且同时测量照射，并且分析使用不同波长的照射光在每个测量步骤中获得的测量信号之间的差。

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