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1. 发明公开

US20230338298A1 PLANT PROTEIN-BASED MICROCAPSULES 审中-公开
公开(公告)号：US20230338298A1
公开(公告)日：2023-10-26
申请号：US18025782
申请日：2021-09-09
申请人： XAMPLA LIMITED , CAMBRIDGE ENTERPRISE LIMITED
发明人： Marc Rodriguez Garcia , Tuomas Pertti Jonathan Knowles , Jack Henry Jeremy Cordrey , Ioana-Alina Dumitru
IPC分类号： A61K9/50 , A23L33/185 , A23L33/15 , A23D7/005 , A23J3/14 , A23D7/04 , A23P10/30 , A61K8/11 , A61Q19/00 , A61K8/06 , A61K8/67 , A61K31/675
CPC分类号： A61K9/5052 , A23L33/185 , A23L33/15 , A23D7/0053 , A23J3/14 , A23D7/04 , A23P10/30 , A61K9/5089 , A61K8/11 , A61Q19/00 , A61K8/064 , A61K8/673 , A61K31/675 , A61K2800/10 , A61K2800/412 , A61K2800/30
摘要： The present invention relates to plant-based microcapsules for the efficient encapsulation and retention of water-soluble ingredients, as well as the efficient co-encapsulation of water-soluble and water-insoluble ingredients. The present invention also relates to compositions comprising the microcapsules, a method of making the microcapsules and compositions, and to uses of the microcapsules and compositions.

2. 发明公开

US20240271145A1 METHODS OF EUKARYOTIC GENE EXPRESSION 审中-公开
公开(公告)号：US20240271145A1
公开(公告)日：2024-08-15
申请号：US18568457
申请日：2022-06-20
申请人： CAMBRIDGE ENTERPRISE LIMITED
发明人： Kärt TOMBERG , Allan BRADLEY
IPC分类号： C12N15/67 , C12N15/10 , C12N15/79
CPC分类号： C12N15/67 , C12N15/10 , C12N15/79
摘要： This invention related to methods of adapting or modifying a complementary DNA (cDNA) sequence for expression in a eukaryotic cell. A nucleic acid molecule is provided that comprises a cDNA sequence that includes two or more splicing consensus motifs that divide the cDNA sequence into exon regions of 50 to 1200 nucleotides. Heterologous introns are then inserted into the splicing consensus motifs of the cDNA sequence, wherein each heterologous intron comprises a 3′ region having a GC content that is equal to or lower than the GC content of a 5′ region of the immediately downstream exon region. This produces a nucleic acid molecule comprising a modified cDNA sequence for expression in a eukaryotic cell. Methods, recombinant nucleic acid comprising a cDNA sequence, expression vectors comprising the recombinant nucleic acid and eukaryotic cells comprising a recombinant nucleic acid or expression vector are provided.

3. 发明授权

US11983875B2 Method and apparatus for analysing intracoronary images 有权
公开(公告)号：US11983875B2
公开(公告)日：2024-05-14
申请号：US17606996
申请日：2020-04-30
申请人： CAMBRIDGE ENTERPRISE LIMITED
发明人： Adam Woolf , Martin Bennett
IPC分类号： G06V10/764 , A61B5/00 , G06T7/00 , G06V10/40 , G06V10/766 , G06V10/774 , G06V10/82 , G16H30/20
CPC分类号： G06T7/0016 , A61B5/0066 , G06V10/40 , G06V10/764 , G06V10/766 , G06V10/774 , G06V10/82 , G16H30/20 , A61B2576/00 , G06T2207/10101 , G06T2207/20081 , G06T2207/20084 , G06T2207/30048 , G06T2207/30101 , G06T2207/30168 , G06V2201/03
摘要： Embodiments of the present techniques provide apparatus and methods for analysing intracoronary images, for example to predict the likelihood of a disease, disease presentation or event, and/or to track performance of a drug or other treatment. The method may comprise: for each image in the set of images of a coronary artery: classifying the image, using a first neural network, for the presence or absence of diseased tissue; when the image is classified as having diseased tissue present, classifying the image, using a second neural network, for the presence or absence of an artefact; determining whether to analyse the image based on the classifying steps; when the image is to be analysed, analysing the image by identifying, using a third neural network, one or more features of interest in a coronary artery tissue; and measuring each identified feature of interest.

4. 发明授权

US11959923B2 Fluidic separation and detection 有权
公开(公告)号：US11959923B2
公开(公告)日：2024-04-16
申请号：US17314254
申请日：2021-05-07
申请人： Cambridge Enterprise Limited
发明人： Emma Yates , Christopher Dobson , Therese Herling , Tuomas Pertti Jonathan Knowles
IPC分类号： G01N33/68 , B01L3/00 , G01N15/02 , G01N27/447 , G01N33/50 , G01N33/52 , G01N15/00
CPC分类号： G01N33/6845 , B01L3/502753 , G01N15/0266 , G01N27/447 , G01N33/50 , G01N33/52 , B01L2200/0631 , B01L2200/0636 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2400/0421 , G01N2015/0038 , G01N2015/0288
摘要： Flow apparatuses comprising a separation channel, a downstream flow separator, a detection zone, an observation zone, and a waste channel. The separation channel has first and second flows in contact and allows lateral movement of components between contacting first and second flows. The downstream flow separator is in communication with the separation channel and diverts a part of the first fluid flow, the second fluid flow, or both, from the separation channel. The detection zone comprises a detection channel downstream of and in communication with the flow separator and configured to receive a plurality of diverted flows from the flow separator and a label channel configured to label the diverted flows from the flow separator. The observation zone is configured to record an analytical signal indicative of the quantity and the electrical properties of the component. The waste channel is at the downstream end of the observation zone.

5. 发明授权

US11883228B2 Smart stethoscopes 有权
公开(公告)号：US11883228B2
公开(公告)日：2024-01-30
申请号：US16978932
申请日：2019-02-20
申请人： Cambridge Enterprise Limited
发明人： Anurag Agarwal , Edmund Kay , Andrew McDonald
IPC分类号： A61B7/04 , A61B5/00
CPC分类号： A61B7/04 , A61B5/7264
摘要： An electronic stethoscope system comprising a device to capture an acoustic heart signal from a patient and a neural network to classify the data into heart sound categories to provide time series sound category data comprising, for each of a succession of time intervals, category probability data representing a probability of the acoustic signal falling into each of the categories. The stethoscope also includes one or more heart state models each having a sequence of heart cardiac cycle states, a system to fit the time series sound category data to the models and determine timing data for the sequence of heart states and a confidence value for the model fit, and an output to output one or both of a model fit indication dependent upon the confidence value and an indication of the timing data.

6. 发明公开

US20230404777A1 A MICROFLUIDIC SENSOR 审中-公开
公开(公告)号：US20230404777A1
公开(公告)日：2023-12-21
申请号：US18043438
申请日：2021-08-27
申请人： CAMBRIDGE ENTERPRISE LIMITED
发明人： Sohini KAR-NARAYAN , Qingshen JING , Jehangir CAMA , Liam IVES , Vikas KHANDUJA
IPC分类号： A61F2/46 , G01L1/14 , G01L1/02 , B81B3/00 , B81B7/00 , B81C1/00
CPC分类号： A61F2/468 , G01L1/142 , G01L1/02 , B81B3/0075 , B81B7/0025 , B81C1/00674 , B81C2203/032 , B81B2203/0338 , B81B2203/04 , B81B2207/115 , B81C2201/0185 , B81C2201/034 , B81B2201/05
摘要： A microfluidic sensor comprising: a first substrate; a second substrate; a cavity formed between the first substrate and the second substrate, the cavity comprising a reservoir portion and a channel portion extending from the reservoir portion; a capacitive element disposed between the first substrate and the second substrate, the capacitive element being at least partially disposed in the channel portion of the cavity; and a dielectric sensing liquid provided in the reservoir portion. Upon application of a force to the first substrate adjacent the reservoir portion, the reservoir portion is configured to deform and displace the sensing liquid along the channel portion, so as to change the capacitance of the capacitive element within the channel portion.

7. 发明公开

US20230393387A1 GHOST IMAGE FREE PROJECTION AT ARBITRARY DISTANCE 审中-公开
公开(公告)号：US20230393387A1
公开(公告)日：2023-12-07
申请号：US18033225
申请日：2021-10-21
申请人： CAMBRIDGE ENTERPRISE LIMITED
发明人： Daping Chu , Yuanbo Deng
IPC分类号： G02B27/00 , G02B27/01 , G02B5/02
CPC分类号： G02B27/0018 , G02B5/0252 , G02B27/0103
摘要： An image generation system for providing a ghost image free head-up display, the system comprising a display screen having a front surface and a back surface, a picture generation unit for projecting an image towards the display screen for reflection towards an eye box, a field lens, and an anisotropic optical component having a first optical power along a first axis and second optical power along a second axis, wherein the first and second axis are perpendicular, wherein the picture generation unit is configured to project light through the field lens such that light is incident on the front surface of the display screen forming a first virtual image, wherein a portion of the light is transmitted through the display screen and is incident on the back surface of the display screen forming a second virtual image, wherein the first and second virtual images are offset along the first axis, wherein the field lens is configured to project the first virtual image at a first projection distance and the second virtual image at a second projection distance such that the offset is below a threshold magnitude and the first and second virtual images are substantially overlaid as viewed from the eye box, and wherein the anisotropic optical component is configured to magnify the first and second virtual image along the second axis only.

8. 发明公开

US20230290556A1 MAGNETIC PARTICLE AND METHOD 审中-公开
公开(公告)号：US20230290556A1
公开(公告)日：2023-09-14
申请号：US18122307
申请日：2023-03-16
申请人： Cambridge Enterprise Limited
发明人： Jeroen Verheyen , Tarun Vemulkar , Russell Cowburn
IPC分类号： H01F10/26 , G01N33/543
CPC分类号： H01F10/265 , G01N33/54326
摘要： A magnetic particle (30, 70) has a layered structure (6, 56) between a top surface of the particle and an opposed bottom surface of the particle. Layers of the structure include one or more non- magnetic layer(s) and one or more magnetized layer(s). The ratio of a lateral dimension of the one or more magnetized layers to the aggregate thickness of the magnetized layer or layers is greater than 500. A plurality of such magnetic particles (30, 70) can be functionalised and marked with readable codes (16, 66) corresponding to the functionalisation, for use for performing assays such as bioassays.

9. 发明公开

US20230242714A1 SILOXANE-BASED LIQUID CRYSTALLINE ELASTOMERS WITH DYNAMIC COVALENT BONDS 审中-公开
公开(公告)号：US20230242714A1
公开(公告)日：2023-08-03
申请号：US17781976
申请日：2020-12-02
申请人： CAMBRIDGE ENTERPRISE LIMITED
发明人： Eugene Terentjev , Mohand Saed
IPC分类号： C08G77/52
CPC分类号： C08G77/52
摘要： The present invention relates to a siloxane-based liquid crystalline elastomer, preferably an exchangeable siloxane-based liquid crystalline elastomer, derived from monomers (A1), (B1) and (C1), wherein (C1) is an acyclic or cyclic vinyl siloxane, and (A1) and (B1) have the following formulae:

wherein is a mesogen, and

Rx and Ry are independently selected from hydrogen or substituted or unsubstituted C1-12 alkyl;

wherein is an organic group.

10. 发明公开

US20230235427A1 DESULFURISATION OF LEAD-CONTAINING WASTE 审中-公开
公开(公告)号：US20230235427A1
公开(公告)日：2023-07-27
申请号：US18190899
申请日：2023-03-27
申请人： EVER RESOURCE LTD , CAMBRIDGE ENTERPRISE LIMITED
发明人： Vimalnath SELVARAJ , Stephen Charles ANDREW , Athan FOX , Ramachandran Vasant KUMAR , Spencer David LOWE , Marcel YIAO
IPC分类号： C22B3/00 , C01G21/06 , C22B1/00 , C22B7/00 , C22B7/02 , H01M10/54
CPC分类号： C22B13/045 , C01G21/06 , C22B1/005 , C22B7/006 , C22B7/02 , H01M10/54
摘要： The present invention relates to the desulfurisation of lead-containing waste. In particular, the present invention relates to a method in which lead-containing waste is desulfurised to form a desulfurised lead-containing waste material which is suitable for recycling into lead or leady oxide. The method is particularly suitable for desulfurising lead-acid battery paste.

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