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1. 发明授权

US09557217B2 Universal multidetection system for microplates 有权
标题翻译：微孔板通用多检测系统
公开(公告)号：US09557217B2
公开(公告)日：2017-01-31
申请号：US13485446
申请日：2012-05-31
申请人： Oleg Zimenkov , Xavier Amouretti , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan J. Venditti, Jr. , Christopher Many , Bill Anderson , Ben Knight , James Piette , Ross Piette , Joe Tobey , Brian Ferris
发明人： Oleg Zimenkov , Xavier Amouretti , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan J. Venditti, Jr. , Christopher Many , Bill Anderson , Ben Knight , James Piette , Ross Piette , Joe Tobey , Brian Ferris
IPC分类号： G01J3/42 , G01J3/02 , G01J3/443 , G01N21/64 , G01N21/76 , G01J3/10 , G01J3/44
CPC分类号： G01J3/42 , G01J3/0218 , G01J3/0224 , G01J3/0235 , G01J3/0264 , G01J3/027 , G01J3/0291 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/64 , G01N21/6447 , G01N21/6452 , G01N21/6456 , G01N21/76 , G01N2021/6463
摘要： An apparatus for optically analyzing a sample may include an imaging subsystem that images the sample, one or more analyzing subsystems that analyze the sample, a temperature control subsystem that controls a temperature of the atmosphere within the apparatus, a gas control subsystem that controls a composition of the atmosphere within the apparatus, and a control module that controls the various subsystems of the apparatus.
摘要翻译：用于光学分析样品的装置可以包括对样品进行成像的成像子系统，分析样品的一个或多个分析子系统，控制装置内的大气温度的温度控制子系统，控制组成的气体控制子系统的装置内的气氛，以及控制装置的各个子系统的控制模块。

2. 发明申请

US20120300194A1 UNIVERSAL MULTIDETECTION SYSTEM FOR MICROPLATES 审中-公开
标题翻译：通用多媒体多媒体系统
公开(公告)号：US20120300194A1
公开(公告)日：2012-11-29
申请号：US13485446
申请日：2012-05-31
申请人： Oleg ZIMENKOV , Xavier AMOURETTI , Michael KONTOROVICH , Ben NORRIS , Richard N. SEARS , Dan J. VENDITTI, JR. , Christopher MANY , Bill Anderson , Ben Knight , James Piette , Ross Piette , Joe Tobey , Brian Ferris
发明人： Oleg ZIMENKOV , Xavier AMOURETTI , Michael KONTOROVICH , Ben NORRIS , Richard N. SEARS , Dan J. VENDITTI, JR. , Christopher MANY , Bill Anderson , Ben Knight , James Piette , Ross Piette , Joe Tobey , Brian Ferris
IPC分类号： G01N21/64 , G01N21/59 , H01L27/146
CPC分类号： G01J3/42 , G01J3/0218 , G01J3/0224 , G01J3/0235 , G01J3/0264 , G01J3/027 , G01J3/0291 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/64 , G01N21/6447 , G01N21/6452 , G01N21/6456 , G01N21/76 , G01N2021/6463
摘要： An apparatus for optically analyzing a sample may include an imaging subsystem that images the sample, one or more analyzing subsystems that analyze the sample, a temperature control subsystem that controls a temperature of the atmosphere within the apparatus, a gas control subsystem that controls a composition of the atmosphere within the apparatus, and a control module that controls the various subsystems of the apparatus.
摘要翻译：用于光学分析样品的装置可以包括对样品进行成像的成像子系统，分析样品的一个或多个分析子系统，控制装置内的大气温度的温度控制子系统，控制组成的气体控制子系统的装置内的气氛，以及控制装置的各个子系统的控制模块。

3. 发明授权

US08218141B2 Universal multidetection system for microplates 有权
标题翻译：微孔板通用多检测系统
公开(公告)号：US08218141B2
公开(公告)日：2012-07-10
申请号：US12838804
申请日：2010-07-19
申请人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
发明人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
IPC分类号： G01J3/18 , G01J3/42 , G01J3/44 , G01N21/64
CPC分类号： G01J3/42 , G01J3/0224 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/6452 , G01N21/76 , G01N2021/6463
摘要： An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.
摘要翻译：提供了用于光学分析样品的装置和方法。该装置包括发射窄波段光的第一光学装置，并具有为光的窄波段提供不同路径的第一滤光器和第一单色仪。该装置还可以包括产生作为宽带激发光的光的光源，在这种情况下，第一光学装置通过第一滤光器或第一单色器传输宽带激发光的窄波段。此外，该装置可以包括第二光学装置，其将宽带激发光的窄波段引导到样本上并接收来自样品的发射光，透射发射光的窄波段的第三光学装置，以及转换将发射光的窄波段变成电信号。

4. 发明授权

US07782454B2 Universal multidetection system for microplates 有权
标题翻译：微孔板通用多检测系统
公开(公告)号：US07782454B2
公开(公告)日：2010-08-24
申请号：US11802831
申请日：2007-05-25
申请人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
发明人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
IPC分类号： G01J3/44
CPC分类号： G01J3/42 , G01J3/0224 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/6452 , G01N21/76 , G01N2021/6463
摘要： An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.
摘要翻译：提供了用于光学分析样品的装置和方法。该装置包括发射窄波段光的第一光学装置，并具有为光的窄波段提供不同路径的第一滤光器和第一单色仪。该装置还可以包括产生作为宽带激发光的光的光源，在这种情况下，第一光学装置通过第一滤光器或第一单色器传输宽带激发光的窄波段。此外，该装置可以包括第二光学装置，其将宽带激发光的窄波段引导到样本上并接收来自样品的发射光，透射发射光的窄波段的第三光学装置，以及转换将发射光的窄波段变成电信号。

5. 发明申请

US20080191149A1 Universal multidetection system for microplates 有权
标题翻译：微孔板通用多检测系统
公开(公告)号：US20080191149A1
公开(公告)日：2008-08-14
申请号：US11802831
申请日：2007-05-25
申请人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
发明人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
IPC分类号： G01J3/30 , G21G5/00
CPC分类号： G01J3/42 , G01J3/0224 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/6452 , G01N21/76 , G01N2021/6463
摘要： An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.
摘要翻译：提供了用于光学分析样品的装置和方法。该装置包括发射窄波段光的第一光学装置，并具有为光的窄波段提供不同路径的第一滤光器和第一单色仪。该装置还可以包括产生作为宽带激发光的光的光源，在这种情况下，第一光学装置通过第一滤光器或第一单色器传输宽带激发光的窄波段。此外，该装置可以包括第二光学装置，其将宽带激发光的窄波段引导到样本上并接收来自样品的发射光，透射发射光的窄波段的第三光学装置，以及转换将发射光的窄波段变成电信号。

6. 发明授权

US6141572A Process and system for simultaneously simulating arterial and non-arterial blood oxygen values for pulse oximetry 有权
标题翻译：用于同时模拟脉搏血氧测定的动脉和非动脉血氧值的过程和系统
公开(公告)号：US6141572A
公开(公告)日：2000-10-31
申请号：US252013
申请日：1999-02-18
申请人： Peter Haas
发明人： Peter Haas
IPC分类号： A61B5/00
CPC分类号： A61B5/1495 , A61B2560/0233
摘要： A problem in pulse oximetry is discriminating between arterial and non-arterial oxygen. Non-arterial oxygen can become detectable by an oximeter when a patient moves, obscuring the oximeter's measurement of arterial oxygen at critical times. Recent advances in pulse oximetry have made it possible to make the discrimination between arterial and non-arterial blood oxygen values. To allow manufacturers, hospitals, and medical researchers to evaluate the new oximetry technology, and evaluate oximeters which use it, new simulation technology is presented which can simulate simultaneous arterial and non-arterial blood oxygen on demand, with precision as to oxygen value, waveform amplitude, and waveform frequency. This invention provides the required simulation by double amplitude modulating the red and infra-red oximeter pulses.
摘要翻译：脉搏血氧饱和度测定中的一个问题是区分动脉和非动脉氧。当患者移动时，血氧饱和度测量仪可以检测到非动脉氧，阻止血氧计在关键时刻对动脉氧的测量。脉搏血氧饱和度测量的最新进展使得有可能区分动脉和非动脉血氧值。为了使制造商，医院和医学研究人员能够评估新的血氧饱和度测定技术，并对使用它的血氧仪进行评估，提出了新的模拟技术，可以根据需要模拟同时动脉和非动脉血氧，氧气值，波形幅度和波形频率。本发明通过双幅度调制红外和红外线血氧仪脉冲提供所需的模拟。

7. 发明申请

US20100277725A1 UNIVERSAL MULTIDETECTION SYSTEM FOR MICROPLATES 有权
标题翻译：通用多媒体多媒体系统
公开(公告)号：US20100277725A1
公开(公告)日：2010-11-04
申请号：US12838804
申请日：2010-07-19
申请人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
发明人： Oleg Zimenkov , Xavier Amouretti , Robert M. Gifford , Mark R. Kennedy , Michael Kontorovich , Ben Norris , Richard N. Sears , Dan Venditti , Christopher Many
IPC分类号： G01J3/42
CPC分类号： G01J3/42 , G01J3/0224 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/6452 , G01N21/76 , G01N2021/6463
摘要： An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.
摘要翻译：提供了用于光学分析样品的装置和方法。该装置包括发射窄波段光的第一光学装置，并具有为光的窄波段提供不同路径的第一滤光器和第一单色仪。该装置还可以包括产生作为宽带激发光的光的光源，在这种情况下，第一光学装置通过第一滤光器或第一单色器传输宽带激发光的窄波段。此外，该装置可以包括第二光学装置，其将宽带激发光的窄波段引导到样本上并接收来自样品的发射光，透射发射光的窄波段的第三光学装置，以及转换将发射光的窄波段变成电信号。

8. 发明申请

US20090032064A1 PLATE WASHING SYSTEM WITH ULTRASONIC CLEANING OF PIPES AND A CONTROL METHOD THEREOF 有权
标题翻译：具有超声波清洗管道的板式洗涤系统及其控制方法
公开(公告)号：US20090032064A1
公开(公告)日：2009-02-05
申请号：US12243822
申请日：2008-10-01
申请人： Robert M. GIFFORD , Lenore Buehrer , Thomas A. Cleveland
发明人： Robert M. GIFFORD , Lenore Buehrer , Thomas A. Cleveland
IPC分类号： B08B3/12 , B08B7/04 , B08B9/00
CPC分类号： B08B3/044 , B01L99/00 , B01L2200/143 , B01L2300/0829 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , B08B3/12 , B08B9/00 , B08B2209/005 , G01N35/1004 , G01N2035/00554
摘要： An automated method of cleaning the pipes of a plate washing system is provided. The plate washing system includes at least one manifold having a plurality of pipes configured to be provided within wells of a plate in order to wash the wells, an ultrasonic transducer mounted to a tank, and a control system. The plate washing system also includes sensors to sense the position of the pipes relative to plate and the tank, and the fluid level within the wells of the plate. The method includes dispensing fluid to the tank, submerging the tips of the pipes within the fluid, activating the ultrasonic transducer in order to vibrate the fluid, and aspirating the fluid from the tank. The control system may initiate a cleaning operation at the request of the user, at a scheduled interval, or when the level sensing system detects a decrease in instrument function.
摘要翻译：提供了清洗洗板系统的管道的自动化方法。洗板系统包括至少一个歧管，其具有多个管，其配置成设置在板的井内以便清洗井，安装到罐的超声换能器和控制系统。洗板系统还包括用于感测管道相对于板和罐的位置的传感器以及板的孔内的液位。该方法包括将液体分配到罐中，将管道的顶端浸没在流体内，激活超声波换能器以振动流体，并从罐吸出流体。控制系统可以按照用户的请求，以预定的间隔，或当液位感测系统检测到仪器功能的降低时，开始清洁操作。

9. 发明申请

US20170108438A1 UNIVERSAL MULTIDETECTION SYSTEM FOR MICROPLATES 审中-公开
公开(公告)号：US20170108438A1
公开(公告)日：2017-04-20
申请号：US15390128
申请日：2016-12-23
申请人： BTI HOLDINGS, INC.
发明人： Oleg ZIMENKOV , Xavier AMOURETTI , Michael KONTOROVICH , Ben NORRIS , Richard N. SEARS , Dan J. VENDITTI, JR. , Christopher MANY , Bill ANDERSON , Ben KNIGHT , James PIETTE , Ross PIETTE , Joe TOBEY , Brian FERRIS
IPC分类号： G01N21/64 , G01N21/76
CPC分类号： G01J3/42 , G01J3/0218 , G01J3/0224 , G01J3/0235 , G01J3/0264 , G01J3/027 , G01J3/0291 , G01J3/0294 , G01J3/10 , G01J3/4406 , G01J3/443 , G01N21/64 , G01N21/6447 , G01N21/6452 , G01N21/6456 , G01N21/76 , G01N2021/6463
摘要： An apparatus for optically analyzing a sample may include an imaging subsystem that images the sample, one or more analyzing subsystems that analyze the sample, a temperature control subsystem that controls a temperature of the atmosphere within the apparatus, a gas control subsystem that controls a composition of the atmosphere within the apparatus, and a control module that controls the various subsystems of the apparatus.

10. 发明授权

US08858718B2 Plate washing system with ultrasonic cleaning of pipes and a control method thereof 有权
标题翻译：具有超声波清洗管道的洗板系统及其控制方法
公开(公告)号：US08858718B2
公开(公告)日：2014-10-14
申请号：US12243822
申请日：2008-10-01
申请人： Robert M. Gifford , Lenore Buehrer , Thomas A. Cleveland
发明人： Robert M. Gifford , Lenore Buehrer , Thomas A. Cleveland
IPC分类号： B08B7/00 , B08B7/04 , B01L99/00 , B08B3/12 , B08B3/04 , G01N35/10 , B08B9/00 , G01N35/00
CPC分类号： B08B3/044 , B01L99/00 , B01L2200/143 , B01L2300/0829 , B01L2300/0864 , B01L2400/0439 , B01L2400/0487 , B08B3/12 , B08B9/00 , B08B2209/005 , G01N35/1004 , G01N2035/00554
摘要： An automated method of cleaning the pipes of a plate washing system is provided. The plate washing system includes at least one manifold having a plurality of pipes configured to be provided within wells of a plate in order to wash the wells, an ultrasonic transducer mounted to a tank, and a control system. The plate washing system also includes sensors to sense the position of the pipes relative to plate and the tank, and the fluid level within the wells of the plate. The method includes dispensing fluid to the tank, submerging the tips of the pipes within the fluid, activating the ultrasonic transducer in order to vibrate the fluid, and aspirating the fluid from the tank. The control system may initiate a cleaning operation at the request of the user, at a scheduled interval, or when the level sensing system detects a decrease in instrument function.
摘要翻译：提供了清洗洗板系统的管道的自动化方法。洗板系统包括至少一个歧管，其具有多个管，其配置成设置在板的井内以便清洗井，安装到罐的超声换能器和控制系统。洗板系统还包括用于感测管道相对于板和罐的位置的传感器以及板的孔内的液位。该方法包括将液体分配到罐中，将管道的顶端浸没在流体内，激活超声波换能器以振动流体，并从罐吸出流体。控制系统可以按照用户的请求，以预定的间隔，或当液位感测系统检测到仪器功能的降低时，开始清洁操作。

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