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    • 4. 发明申请
    • POLYMER-BASED STENT ASSEMBLY
    • 基于聚合物的固定装置
    • US20100204778A1
    • 2010-08-12
    • US12764447
    • 2010-04-21
    • Antoine LaFontSerge Piranda Statice SantePatrick SabariaTahmer SharkawiMichel Vert
    • Antoine LaFontSerge Piranda Statice SantePatrick SabariaTahmer SharkawiMichel Vert
    • A61F2/82
    • A61F2/82A61F2/958A61F2002/9522A61F2210/0004A61L31/06C08L67/04
    • Methods for preparing a polymer-based stent assembly comprising an inflatable balloon catheter and a polymer-based stent resistant to relaxation-related negative recoil are provided. The methods comprise heating a polymeric cylindrical device which is at a final predetermined shape and diameter to a temperature sufficiently above the glass transition temperature (Tg) of the polymer and for a time sufficient to erase any memory of previous processing of the polymeric cylindrical device and then quenching the polymeric cylindrical device to provide an educated polymeric cylindrical device having a memory of the final predetermined diameter and shape, mounting the educated cylindrical device on an inflatable balloon catheter, reducing the diameter of the educated cylindrical device by heating to a temperature at or slightly above the Tg of the polymer while evenly applying pressure on the exterior surface of the wall of the cylindrical device, and then cooling the cylindrical device below the Tg of the polymer to provide a stent assembly comprising an inflatable balloon catheter and an expandable, educated, polymeric stent snugly and stably disposed thereon. Assemblies comprising an inflatable balloon and a polymer based stent that is substantially resistant to relaxation related recoil mounted snugly on the balloon are also provided.
    • 提供了一种制备基于聚合物的支架组件的方法,其包括可膨胀的气囊导管和抗放松相关的负反冲的基于聚合物的支架。 该方法包括将最终预定形状和直径的聚合物圆柱形装置加热到足够高于聚合物的玻璃化转变温度(Tg)的温度,并且足以消除聚合物圆柱形装置的先前处理的任何记忆的时间,以及 然后淬灭聚合物圆柱形装置,以提供具有最终预定直径和形状的记忆的受过教育的聚合物圆柱形装置,将受过教育的圆柱形装置安装在可充气气囊导管上,通过加热至或在其上的温度减小受过教育的圆柱形装置的直径, 稍微高于聚合物的Tg,同时在圆柱形装置的壁的外表面上均匀地施加压力,然后将圆柱形装置冷却到聚合物的Tg以下,以提供包括可充气气囊导管和可扩展的受过教育的 ,聚合物支架紧贴且稳定地设置在其上。 还提供了包括充气气囊和基于聚合物的支架的组件,其基本上抵抗紧贴在气囊上的松弛相关反冲。
    • 5. 发明授权
    • Polymer-based stent assembly
    • 基于聚合物的支架组件
    • US07731740B2
    • 2010-06-08
    • US10508739
    • 2004-04-02
    • Antoine LaFontSerge Piranda Statice SantePatrick SabariaTahmer SharkawiMichel Vert
    • Antoine LaFontSerge Piranda Statice SantePatrick SabariaTahmer SharkawiMichel Vert
    • A61F2/06
    • A61F2/82A61F2/958A61F2002/9522A61F2210/0004A61L31/06C08L67/04
    • Methods for preparing a polymer-based stent assembly comprising an inflatable balloon catheter and a polymer-based stent resistant to relaxation-related negative recoil are provided. The methods comprise heating a polymeric cylindrical device which is at a final predetermined shape and diameter to a temperature sufficiently above the glass transition temperature (Tg) of the polymer and for a time sufficient to erase any memory of previous processing of the polymeric cylindrical device and then quenching the polymeric cylindrical device to provide an educated polymeric cylindrical device having a memory of the final predetermined diameter and shape, mounting the educated cylindrical device on an inflatable balloon catheter, reducing the diameter of the educated cylindrical device by heating to a temperature at or slightly above the Tg of the polymer while evenly applying pressure on the exterior surface of the wall of the cylindrical device, and then cooling the cylindrical device below the Tg of the polymer to provide a stent assembly comprising an inflatable balloon catheter and an expandable, educated, polymeric stent snugly and stably disposed thereon. Assemblies comprising an inflatable balloon and a polymer based stent that is substantially resistant to relaxation related recoil mounted snugly on the balloon are also provided.
    • 提供了一种制备基于聚合物的支架组件的方法,其包括可膨胀的气囊导管和抗放松相关的负反冲的基于聚合物的支架。 该方法包括将最终预定形状和直径的聚合物圆柱形装置加热到足够高于聚合物的玻璃化转变温度(Tg)的温度,并且足以消除聚合物圆柱形装置的先前处理的任何记忆的时间,以及 然后淬灭聚合物圆柱形装置,以提供具有最终预定直径和形状的记忆的受过教育的聚合物圆柱形装置,将受过教育的圆柱形装置安装在可充气气囊导管上,通过加热至或在其上的温度减小受过教育的圆柱形装置的直径, 稍微高于聚合物的Tg,同时在圆柱形装置的壁的外表面上均匀地施加压力,然后将圆柱形装置冷却到聚合物的Tg以下,以提供包括可充气气囊导管和可扩展的受过教育的 ,聚合物支架紧贴且稳定地设置在其上。 还提供了包括充气气囊和基于聚合物的支架的组件,其基本上抵抗紧贴在气囊上的松弛相关反冲。