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81. 发明授权

US09123449B2 Infusion system configurations 有权
标题翻译：输液系统配置
公开(公告)号：US09123449B2
公开(公告)日：2015-09-01
申请号：US12865924
申请日：2009-06-11
申请人： Charles R. Quirico , Ernest Balestracci , Rolf E. Swenson , Daniel D. Darst , Eric J. Krause , Vishal N. Lokhande , Jacob S. Childs
发明人： Charles R. Quirico , Ernest Balestracci , Rolf E. Swenson , Daniel D. Darst , Eric J. Krause , Vishal N. Lokhande , Jacob S. Childs
IPC分类号： A61M3/00 , G21G4/08 , A61M5/14 , G21F7/00 , G21G1/00 , A61B6/10 , A61B19/00 , A61M5/00 , A61M5/142 , G21F3/00 , A61K51/00 , A61B6/00 , A61B6/03
CPC分类号： A61M5/007 , A61B6/037 , A61B6/107 , A61B6/481 , A61B6/507 , A61B50/13 , A61B90/39 , A61B2050/105 , A61B2090/392 , A61K51/00 , A61M5/14 , A61M5/1409 , A61M5/142 , A61M5/1452 , A61M5/158 , A61M5/16854 , A61M5/16881 , A61M5/365 , A61M2005/1403 , A61M2205/18 , A61M2205/276 , A61M2205/3375 , A61M2205/50 , A61M2205/505 , A61M2205/52 , A61M2205/584 , A61M2205/587 , A61M2205/6009 , A61M2205/6054 , A61M2205/6072 , A61M2205/70 , A61M2205/75 , A61M2209/084 , A61N5/1001 , A61N5/1007 , A61N5/1075 , A61N2005/1021 , A61N2005/1022 , A61N2005/1074 , A61N2005/1094 , B62B3/005 , G06F19/00 , G06F19/3468 , G06F21/31 , G21F3/00 , G21F7/00 , G21G1/0005 , G21G1/001 , G21G4/08 , G21G2001/0031
摘要： Infusion system configurations and assemblies facilitate routing of infusion circuit tubing lines. Tubing lines are routed into and out from compartments of a shielding assembly for the infusion system, at locations which prevent kinking and/or crushing of the lines, and/or provide for ease in assembling the circuit. A plurality of the lines may be held together by a support frame to form a disposable infusion circuit subassembly, that can further facilitate routing of the lines.
摘要翻译：输液系统配置和组件便于输注电路管线的布线。在防止线路扭结和/或破碎的位置处和/或为组装电路提供便利的位置，将管道线路输入和输出用于输注系统的屏蔽组件的隔间。多个线可以由支撑框架保持在一起以形成一次性输注电路子组件，其可以进一步促进线路的布线。

82. 发明申请

US20150179290A1 System and method for generating molybdenum-99 and metastable technetium-99, and other isotopes 有权
标题翻译：用于生成钼-99和亚稳锝-99以及其他同位素的系统和方法
公开(公告)号：US20150179290A1
公开(公告)日：2015-06-25
申请号：US12928227
申请日：2010-12-07
申请人： James E. Clayton
发明人： James E. Clayton
IPC分类号： G21G1/00 , G21G1/02
CPC分类号： G21G1/0005 , G21G1/001 , G21G1/02 , G21G1/06 , G21G1/10 , G21G1/12 , G21G2001/0036 , G21G2001/0042
摘要： An accelerator based systems are disclosed for the generation of isotopes, such as molybdenum-98 (“99Mo”) and metastable technetium-99 (“99mTc”) from molybdenum-98 (“98Mo”). Multilayer targets are disclosed for use in the system and other systems to generate 99mTc and 98Mo, and other isotopes. In one example a multilayer target comprises a first, inner target of 98Mo surrounded, at least in part, by a separate, second outer layer of 98Mo. In another example, a first target layer of molybdenum-100 is surrounded, at least in part, by a second target layer of 98Mo. In another example, a first inner target comprises a Bremsstrahlung target material surrounded, at least in part, by a second target layer of molybdenum-100, surrounded, at least in part, by a third target layer of 98Mo.
摘要翻译：公开了一种用于产生钼-98（“99Mo”）和亚稳态锝-99（“99mTc”）的钼同位素（“98Mo”）的同位素的加速器系统。公开了多层目标用于系统和其他系统中以产生99mTc和98Mo以及其他同位素。在一个示例中，多层靶包括98Mo的第一内部目标，至少部分由98Mo的单独的第二外层包围。在另一个实例中，钼-100的第一目标层至少部分地被98Mo的第二目标层包围。在另一个示例中，第一内部目标包括至少部分地被第一靶标的钼-100包围的Bre致射线靶材料，至少部分由98Mo的第三目标层包围。

83. 发明授权

US09058908B2 Method for producing actinium-225 and isotopes of radium and target for implementing same 有权
标题翻译：镭225和镭同位素的制备方法及其目的
公开(公告)号：US09058908B2
公开(公告)日：2015-06-16
申请号：US13120186
申请日：2009-09-09
申请人： Boris Leonidovich Zhuikov , Stepan Nikolaevich Kalmykov , Ramiz Avtandilovich Aliev , Stanislav Viktorovich Ermolaev , Vladimir Mikhailovich Kokhanyuk , Nikolai Alexandrovich Konyakhin , Ivan Gundarovich Tananaev , Boris Fedorovich Myasoedov
发明人： Boris Leonidovich Zhuikov , Stepan Nikolaevich Kalmykov , Ramiz Avtandilovich Aliev , Stanislav Viktorovich Ermolaev , Vladimir Mikhailovich Kokhanyuk , Nikolai Alexandrovich Konyakhin , Ivan Gundarovich Tananaev , Boris Fedorovich Myasoedov
IPC分类号： G21G1/00 , G21G1/12
CPC分类号： G21G1/12 , G21G1/001 , G21G2001/0089
摘要： The invention relates to the field of nuclear technology and radiochemistry, more specifically to the production and isolation of radionuclides for medical purposes. The method for producing actinium-225 and isotopes of radium comprises irradiating a solid block of metallic thorium of a thickness of 2 to 30 mm, which is contained within a hermetically sealed casing made of a material which does not react with thorium, with a flow of accelerated charged particles with high intensity. The irradiated metallic thorium is removed from the casing and is either heated with the addition of lanthanum and the distillation of radium or is dissolved in nitric acid with the recovery of actinium-225 by extraction. A target for implementing this method consists of blocks of metallic thorium of a thickness of 2 to 30 mm, which are contained within a hermetically scaled casing made of different materials which do not react with thorium.
摘要翻译：本发明涉及核技术和放射化学领域，更具体地涉及用于医疗目的的放射性核素的生产和分离。制备镭225和镭的同位素的方法包括：将由包含在不与钍反应的材料制成的气密密封的外壳内的厚度为2至30mm的金属钍的固体块照射流的高强度加速带电粒子。被辐射的金属钍被从外壳中取出，加镧加热，蒸馏镭，或者通过萃取回收锕-225溶解在硝酸中。实施该方法的目标包括厚度为2至30mm的金属钍块，其包含在不与钍反应的不同材料制成的密封外壳内。

84. 发明授权

US09047997B2 Techniques for on-demand production of medical isotopes such as Mo-99/Tc-99m and radioactive iodine isotopes including I-131 有权
标题翻译：用于按需生产医用同位素如Mo-99 / Tc-99m和放射性碘同位素（包括I-131）的技术
公开(公告)号：US09047997B2
公开(公告)日：2015-06-02
申请号：US12944634
申请日：2010-11-11
申请人： Francis Yu-Hei Tsang
发明人： Francis Yu-Hei Tsang
IPC分类号： G21G1/00 , G21G1/06 , G21G1/08
CPC分类号： G21G1/08 , G21G1/001 , G21G1/06 , G21G4/02 , G21G2001/0036 , G21G2001/0042 , G21G2001/0063 , G21Y2002/201
摘要： A system for radioisotope production uses fast-neutron-caused fission of depleted or naturally occurring uranium targets in an irradiation chamber. Fast fission can be enhanced by having neutrons encountering the target undergo scattering or reflection to increase each neutron's probability of causing fission (n, f) reactions in U-238. The U-238 can be deployed as layers sandwiched between layers of neutron-reflecting material, or as rods surrounded by neutron-reflecting material.
摘要翻译：用于放射性同位素生产的系统在照射室中使用快中子引起的耗尽或天然存在的铀靶的裂变。通过使遇到目标的中子发生散射或反射以增加每个中子在U-238中引起裂变（n，f）反应的概率，可以提高快速裂变。 U-238可以部署为夹在中子反射材料层之间的层，或者被中子反射材料包围的杆。

85. 发明授权

US09023305B2 Strontium-82/rubidium-82 generator, method for producing a rubidium-82 comprising diagnostic agent, said diagnostic agent and its use in medicine 有权
标题翻译：锶-82 /铷-82发生器，用于制备包含诊断剂的铷-82的方法，所述诊断剂及其在药物中的用途
公开(公告)号：US09023305B2
公开(公告)日：2015-05-05
申请号：US13056103
申请日：2009-08-14
申请人： Roland Anthonius Maria Johannus Claessens
发明人： Roland Anthonius Maria Johannus Claessens
IPC分类号： C01D17/00 , C01F11/00 , G21G1/00 , A61K51/12
CPC分类号： G21G1/001 , A61K51/1282 , G21G1/0005 , G21G2001/0031
摘要： The invention relates to a strontium-82/rubidium-82 generator, comprising a column filled with a cationic exchanger loaded with strontium-82, and having an inlet and an outlet, and a liquid medium, wherein parts of the column, inlet and outlet coming into contact with the liquid medium are iron-free, preferably metal-free, to a method for producing rubidium-82, and to the obtained diagnostic agent.
摘要翻译：本发明涉及一种锶-82 /铷-82发生器，其包括填充有负载锶-82的阳离子交换剂，并具有入口和出口以及液体介质的柱，其中塔的一部分，入口和出口与液体介质接触是无铁，优选不含金属的，涉及生产铷-82的方法和所得诊断剂。

86. 发明申请

US20140226775A1 Liquid Lithium Cooled Fission Reactor for Producing Radioactive Materials 审中-公开
标题翻译：液体锂冷裂变反应堆生产放射性物质
公开(公告)号：US20140226775A1
公开(公告)日：2014-08-14
申请号：US13815218
申请日：2013-02-11
申请人： Alexander Devolpi
发明人： Alexander Devolpi
IPC分类号： G21G1/00
CPC分类号： G21G1/001 , G21C1/03 , G21G1/08 , Y02E30/34 , Y02E30/35
摘要： A liquid lithium-cooled fission reactor optimized for producing radioactive materials. The reactor is designed to enhance the availability of rare radioactive materials that have significant value for national defense, industrial research, and medical care. This invention has tangible design attributes that can be tailored to create one or more scarce and valuable radioactive materials. In particular, the reactor design is optimized for low-cost production of large quantities of radioactive tritium needed in national-defense and fusion-breeder programs. There are four core designs applied to this invention, all of which produce tritium and surplus heat that can generate byproduct electricity, thereby reducing the cost of radioactive-material production. Three of the embodiments furnish radioactive fission products, such as molybdenum-99, that can be extracted with high efficiency and rapid processing, thus fulfilling a critical supply and price shortfall in radioisotopes used for medical diagnosis and treatment.
摘要翻译：用于生产放射性物质的液体锂冷裂变反应堆。反应堆旨在提高对国防，工业研究和医疗保健具有重要价值的稀有放射性物质的可利用性。本发明具有可定制的有形设计属性，以产生一种或多种稀有和有价值的放射性材料。特别地，反应堆设计是针对国防和融合育种计划所需的大量放射性氚的低成本生产进行了优化的。本发明有四种核心设计，它们都产生能够产生副产物电的氚和多余的热量，从而降低了放射性材料生产的成本。其中三个实施例提供可以以高效率和快速加工提取的放射性裂变产物，例如钼-99，从而实现用于医疗诊断和治疗的放射性同位素的关键供应和价格短缺。

87. 发明申请

US20140153684A1 Dry Phase Reactor for Generating Medical Isotopes 有权
标题翻译：用于产生医用同位素的干相反应器
公开(公告)号：US20140153684A1
公开(公告)日：2014-06-05
申请号：US13692212
申请日：2012-12-03
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION
发明人： Thomas Rockwell Mackie , Thad Alexander Heltemes
IPC分类号： G21G1/00
CPC分类号： G21G1/001 , G21G1/06 , G21G2001/0036
摘要： An apparatus for generating medical isotopes provides for the irradiation of dry-phase, granular uranium compounds which are then dissolved in a solvent for separation of the medical isotope from the irradiated compound. Once the medical isotope is removed, the dissolved compound may be reconstituted in dry granular form for repeated irradiation.
摘要翻译：用于生成医用同位素的装置提供了干相颗粒状铀化合物的照射，然后将其溶解在用于将医用同位素与被照射的化合物分离的溶剂中。一旦医用同位素被去除，溶解的化合物可以以干燥的颗粒形式重构用于反复照射。

88. 发明授权

US08715598B2 Method for the purification of radium from different sources 有权
标题翻译：从不同来源净化镭的方法
公开(公告)号：US08715598B2
公开(公告)日：2014-05-06
申请号：US13441803
申请日：2012-04-06
申请人： Eva Kabai , Josue M. Moreno Bermudez , Richard Henkelmann , Andreas Türler
发明人： Eva Kabai , Josue M. Moreno Bermudez , Richard Henkelmann , Andreas Türler
IPC分类号： C01F13/00
CPC分类号： C22B60/00 , C22B3/002 , C22B13/04 , C22B26/20 , G21G1/001 , G21G2001/0094 , Y02P10/234
摘要： The invention is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.
摘要翻译：本发明涉及一种用于纯化镭（特别是226Ra）的方法，用于使用提取色谱从化学上类似的元素如Ba，Sr和Pb分离用于从可用的放射源制备基本上纯的225Ac产物的目标制备从所需的Ra; 其中所述提取色谱法具有基于冠醚的萃取剂体系。本发明涉及一种用于回收226Ra的方法，用于在分离产生的225Ac之后，用加速质子（p，2n）照射的镭源进行225Ac生产的目标制备。在该方法中，使用上述提取色谱和阳离子交换层析的组合。得到的226Ra基本上不含由Ag，Al，As，Be，Bi，Ca，Cd，Co，Cr，Cu，Fe，Ga，K，Li，Mg，Mn，Na，Ni，Pb组成的以下化学污染物，Sr，V，Zn和Ba。

89. 发明授权

US08647595B2 Method for separating radioactive copper using chelating-ion exchange resin 失效
标题翻译：使用螯合离子交换树脂分离放射性铜的方法
公开(公告)号：US08647595B2
公开(公告)日：2014-02-11
申请号：US13001861
申请日：2009-06-17
申请人： Shigeki Watanabe , Noriko Ishioka
发明人： Shigeki Watanabe , Noriko Ishioka
IPC分类号： C01F13/00
CPC分类号： G21G1/001 , B01J45/00 , C22B3/165 , C22B3/42 , C22B7/007 , C22B15/0089 , C22B23/0461 , C22B23/0484 , G21G2001/0094 , Y02P10/234 , Y02P10/236
摘要： Disclosed is a method for rapidly separating radioactive copper from nickel that contains radioactive copper and radioactive cobalt, which comprises dissolving nickel that contains radioactive copper and radioactive cobalt in an acid solution and leading it to pass through a chelating-ion exchange resin-filled column to thereby make nickel, radioactive copper and radioactive cobalt held by the chelating-ion exchange resin, and then leading an acid solution to pass through the chelating-ion exchange resin-filled column to elute nickel and radioactive cobalt, and thereafter leading an acid solution having a higher concentration than that of the previous acid solution to pass through the chelating-ion exchange resin-filled column after nickel and radioactive elution therefrom to thereby elute radioactive copper.
摘要翻译：公开了一种快速分离含有放射性铜和放射性钴的镍的放射性铜的方法，其包括将含有放射性铜和放射性钴的镍溶解在酸性溶液中，并使其通过螯合离子交换树脂填充柱从而使镍，放射性铜和由螯合离子交换树脂保持的放射性钴，然后引导酸溶液通过螯合离子交换树脂填充柱以洗脱镍和放射性钴，然后引入具有比以前的酸溶液的浓度高，在镍之后通过螯合离子交换树脂填充的柱，并从其中进行放射性洗脱，从而洗脱放射性铜。

90. 发明申请

US20130336870A1 Advanced Tritium System for Separation of Tritium from Radioactive Wastes and Reactor Water in Light Water Systems 审中-公开
标题翻译：用于在轻水系统中分离氚与放射性废物和反应堆水的高级氚系统
公开(公告)号：US20130336870A1
公开(公告)日：2013-12-19
申请号：US13863206
申请日：2013-04-15
申请人： Kurion, Inc.
发明人： Mark S. Denton , Walter T. Shmayda
IPC分类号： B01D59/30
CPC分类号： B01D59/30 , B01D59/32 , C01B4/00 , C01B5/00 , C02F1/42 , C02F1/461 , C02F1/725 , C02F2101/006 , C02F2103/18 , G21F9/06 , G21G1/001 , G21G4/00 , G21G2001/0094
摘要： Systems, methods, and processes for a high throughput, low concentration processing of low activity tritiated light water include the electrolysis of at least some of the tritiated water to produce hydrogen and tritium gas. The hydrogen and tritium gas produced by electrolysis in some cases are combined with heated water vapor to increase throughput and passed through a liquid phase catalytic exchange column, which generally includes a catalyst that includes palladium coated with a hydrophobic polymer. As the hydrogen and tritium gas, along with heated water vapor, rise through the LPCE column, the tritium is retained on the catalyst. Deionized wash water passes down the column (i.e., in the opposite direction of the flow of the hydrogen gas and heated water vapor) and carries the retained tritium out of the LPCE column. Useful in separating tritium from radioactive waste materials and from the water from nuclear reactors.
摘要翻译：低活性氚化轻水的高通量，低浓度处理的系统，方法和方法包括至少一些氚化水的电解以产生氢和氚气。通过电解产生的氢气和氚气在一些情况下与加热的水蒸汽结合以增加生产量并通过液相催化交换柱，其通常包括包含用疏水性聚合物涂覆的钯的催化剂。由于氢气和氚气体以及加热的水蒸汽通过LPCE柱上升，氚保留在催化剂上。去离子的洗涤水通过柱（即，在与氢气和加热的水蒸汽的流动的相反方向）下运送并将保留的氚输出LPCE柱。可用于将氚与放射性废物和核反应堆的水分离。

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