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    • 83. 发明授权
    • Cross-linked hydroxypropylcellulose microcapsules and process for making
    • 交联羟丙基纤维素微胶囊及其制备方法
    • US4025455A
    • 1977-05-24
    • US673003
    • 1976-04-02
    • Dale Richard Shackle
    • Dale Richard Shackle
    • B01J13/08B01J13/16B41M5/165B01J13/02
    • B41M5/165B01J13/08B01J13/16Y10S428/914Y10T428/249963Y10T428/2985
    • This invention relates to a process for forming microcapsules comprising the steps of preparing an aqueous solution containing a hydroxypropylcellulose wall forming compound, the hydroxypropylcellulose wall forming compound containing reactive hydroxyl groups and being characterized by having decreasing solubility with increasing temperature in aqueous solution. An oil solution is prepared containing an oil soluble cross-linking agent for the hydroxypropylcellulose wall forming compound in an oil to be encapsulated, the oil soluble cross-linking agent being a polyfunctional isocyanate containing more than one group capable of reacting with hydroxyl groups to provide cross-linkage with the hydroxypropylcellulose wall forming compound. The aqueous solution containing hydroxypropylcellulose is mixed with the oil solution containing the cross-linking agent in a manner such that an emulsion is formed having droplets of the oil solution dispersed in the aqueous solution. The mixture is heated to a temperature of from about 45.degree. C to about 52.degree. C to cause the formation of a precipitate of the hydroxypropylcellulose wall forming compound on the droplets of the oil solution, the precipitate resulting from the interaction of the hydroxypropylcellulose wall forming compound and the polyfunctional isocyanate cross-linking agent to form microcapsule walls. The temperature of the heated mixture is maintained at a temperature and for a time sufficient to permit the microcapsule walls to become substantially oil and water impermeable. This invention also relates to the microcapsules produced by the process of this invention.
    • 本发明涉及一种形成微胶囊的方法,其包括以下步骤:制备含有羟丙基纤维素壁形成化合物的水溶液,所述羟丙基纤维素壁形成化合物含有反应性羟基,并且其特征在于在水溶液中随温度升高而降低溶解度。 制备的油溶液含有待包封的油中的羟丙基纤维素壁形成化合物的油溶性交联剂,该油溶性交联剂是含有多于一个能够与羟基反应的基团的多官能异氰酸酯,以提供 与羟丙基纤维素壁形成化合物交联。 将含有羟丙基纤维素的水溶液与含有交联剂的油溶液以形成具有分散在水溶液中的油溶液的液滴的方式混合。 将混合物加热至约45℃至约52℃的温度,以使形成羟丙基纤维素壁的化合物的沉淀物形成在油溶液的液滴上,由于形成羟丙基纤维素壁的相互作用而产生的沉淀 化合物和多官能异氰酸酯交联剂形成微胶囊壁。 加热的混合物的温度保持在足以允许微胶囊壁变得基本上油和水不渗透的温度和一段时间。 本发明还涉及通过本发明的方法生产的微胶囊。