专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20140348825A1 COMPOSITIONS AND METHODS TO MODULATE CELL ACTIVITY 有权
标题翻译：组合物和调节细胞活性的方法
公开(公告)号：US20140348825A1
公开(公告)日：2014-11-27
申请号：US14239427
申请日：2012-08-24
申请人： Jeffrey Friedman , Sarah Stanley
发明人： Jeffrey Friedman , Sarah Stanley
IPC分类号： A61K41/00 , A61K33/26
CPC分类号： A61K41/0052 , A61K9/16 , A61K9/1611 , A61K9/167 , A61K33/26 , A61K38/1709 , A61K38/1767 , A61K41/0028 , A61K47/6929 , A61N1/406 , B82Y5/00 , C07K14/47 , C07K14/705 , C07K16/18 , C07K2317/22 , C07K2317/92 , C07K2317/94 , C07K2319/00 , C07K2319/035 , C07K2319/21 , C07K2319/30 , C07K2319/60
摘要： The present invention provides methods and compositions for the remote control of cell function based on the use of radiofrequency waves to excite nanoparticles targeted to specific cell types. The nanoparticles may be applied to the target cell extracellularly and/or expressed intracellularly. The cell type of interest expresses a temperature sensitive channel wherein excitation of the nanoparticles results in a localized temperature increase that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject. Accordingly, the invention provides a generic approach for treatment of any disease associated with a protein deficiency.
摘要翻译：本发明提供了基于使用射频波激发靶向特定细胞类型的纳米颗粒来远程控制细胞功能的方法和组合物。可以在细胞外细胞外和/或细胞内表达纳米颗粒。感兴趣的细胞类型表达温度敏感通道，其中纳米颗粒的激发导致局限性温度升高，其被转导成细胞反应。这样的细胞应答可能包括例如导致产生一种或多种生理活性蛋白质的基因表达增加。这些蛋白质的表达可用于治疗受试者中各种不同的遗传或获得性疾病或病症。因此，本发明提供了治疗与蛋白质缺乏相关的任何疾病的通用方法。

82. 发明申请

US20140249351A1 MICROPARTICLES FOR SELECTIVELY TARGETED HYPERTHERMIA 审中-公开
标题翻译：用于选择性高血压的微量元素
公开(公告)号：US20140249351A1
公开(公告)日：2014-09-04
申请号：US14279045
申请日：2014-05-15
申请人： Sirtex Medical Limited
发明人： Stephen Keith Jones , Katrina Francis Rutherford , Andrew John Ruys , Bruce Nathaniel Gray
IPC分类号： A61K41/00 , A61N2/00 , A61K9/14
CPC分类号： A61K41/0052 , A61K9/14 , A61N1/406 , A61N2/004
摘要： A microparticle composition(s) comprising nanomagnetic particles and a matrix, wherein said microparticle composition(s) have a least one of the following properties: (a) a VAR of at least about 1 Watts/cm3 subject to appropriate field conditions; (b) a density of about 2.7 or less: or (c) a size of about 100 nm to about 200 microns.
摘要翻译：一种包含纳米磁性颗粒和基质的微粒组合物，其中所述微粒组合物具有以下特性中的至少一种：（a）在适当的场条件下，至少约1瓦/ cm 3的VAR; （b）约2.7或更小的密度：或（c）约100nm至约200微米的尺寸。

83. 发明申请

US20140243701A1 Temperature Measurement System and Method 审中-公开
标题翻译：温度测量系统及方法
公开(公告)号：US20140243701A1
公开(公告)日：2014-08-28
申请号：US14186465
申请日：2014-02-21
申请人： RESONANT CIRCUITS LTD
发明人： Paul Southern , Simon Hattersley
IPC分类号： A61B5/01
CPC分类号： A61B5/01 , A61N1/406 , G01K7/38 , G01K13/002
摘要： A method and apparatus for measuring the change in temperature of a material being heated. In one embodiment, the method includes introducing particles having magnetic susceptibility into the material; heating the material and particles; measuring, using a circuit having a resonant frequency, the change in the resonant frequency of the circuit as the temperature of the particles changes; and correlating the change in resonant frequency to a change in temperature. In one embodiment, the apparatus includes a collection of magnetic particles in contact with the material undergoing heating; a resonance circuit including a tank circuit including a coil and capacitance and having a resonant frequency; an alternating current variable frequency source capable of tracking changes in the resonant frequency of the tank circuit to maintain the frequency of the alternating current at the resonant frequency of the tank circuit; and a processor in communication with the alternating current source.
摘要翻译：一种用于测量被加热材料的温度变化的方法和装置。在一个实施方案中，该方法包括将具有磁化率的颗粒引入材料中; 加热材料和颗粒; 使用具有共振频率的电路，随着颗粒的温度改变，电路的谐振频率的变化; 并将谐振频率的变化与温度变化相关联。在一个实施例中，该装置包括与经历加热的材料接触的磁性颗粒的集合; 谐振电路，包括具有线圈和电容并具有谐振频率的振荡电路; 交流电可变频率源，其能够跟踪所述振荡电路的谐振频率的变化，以将所述交流电流的频率保持在所述振荡电路的谐振频率处; 以及与交流电源通信的处理器。

84. 发明申请

US20140207109A1 SYSTEM FOR DEPLOYING AN INDUCTIVE SHAPE MEMORY CATHETERIZATION DEVICE AND METHODS FOR USE THEREWITH 有权
标题翻译：引入形状记忆体导入装置的系统及其使用方法
公开(公告)号：US20140207109A1
公开(公告)日：2014-07-24
申请号：US13956536
申请日：2013-08-01
申请人： Memory Effect Medical, LLC
发明人： Christine Laramy , Bruce Stuckman
IPC分类号： A61M25/01
CPC分类号： A61F2/95 , A61B17/12113 , A61B17/12145 , A61B2017/00115 , A61B2017/00411 , A61B2017/00867 , A61B2017/00871 , A61B2017/12077 , A61F2002/9505 , A61F2250/0001 , A61F2250/0067 , A61M25/0043 , A61M2025/0064 , A61N1/406
摘要： A system for deploying a shape memory catheterization device within a patient, includes a catheter for endovascular insertion of the shape memory catheterization device. A heat source heats the shape memory catheterization device above the transition temperature. A transformation data generator includes a circuit driver for driving a circuit that includes at least one inductive element of the shape memory catheterization device and a detection circuit for generating transformation data based on an inductance of the at least one inductive element, wherein the transformation data indicates a shape transformation of the shape memory catheterization device from a catheterization shape to a transformed shape.
摘要翻译：用于在患者体内部署形状记忆导管插入装置的系统包括用于形状记忆导管插入装置的血管内插入的导管。热源将形状记忆导管装置加热到转变温度以上。变换数据发生器包括用于驱动电路的电路驱动器，该电路包括形状记忆导管装置的至少一个感应元件和用于基于至少一个电感元件的电感产生变换数据的检测电路，其中变换数据指示形状记忆导管插入装置从导管插入形状到变形形状的形状变换。

85. 发明申请

US20140149092A1 COMPUTER-AIDED SIMULATION TOOL FOR PROVIDING ASSISTANCE IN THE PLANNING OF THERMOTHERAPY 有权
标题翻译：计算机辅助模拟工具，用于在热神规划中提供帮助
公开(公告)号：US20140149092A1
公开(公告)日：2014-05-29
申请号：US13989313
申请日：2012-03-08
申请人： Jacek Nadobny , Peng Liu , Jens-Thorsten Ollek , Heike C. Bender
发明人： Jacek Nadobny , Peng Liu , Jens-Thorsten Ollek , Heike C. Bender
IPC分类号： G06F19/00
CPC分类号： A61N2/004 , A61B34/10 , A61K9/5094 , A61K41/0052 , A61N1/406 , A61N2/00 , G06F19/00 , G16H50/50
摘要： The invention relates to a computer-aided simulation tool, in particular to computer-aided simulation methods, for providing assistance in the planning of thermotherapy, and to suitably configured computer equipment. The thermotherapy comprises hyperthermic treatment of a tumour volume within a volume of a human body. The hyperthermic treatment comprises the application of a magnetic field within a treatment volume by means of a magnetic field applicator. In at least one depot volume, thermal energy can be introduced by means of magnetic, paramagnetic and/or superparamagnetic nanoparticles deposited in the body, by power absorption in the applied magnetic field. Field strength values and optionally calculated temperature distributions are provided for assisting the user in the planning of the thermotherapy.
摘要翻译：本发明涉及一种计算机辅助模拟工具，特别是涉及计算机辅助模拟方法，用于在热疗计划中提供帮助，以及适当配置的计算机设备。热疗包括对体内体积肿瘤体积的高热治疗。高温处理包括通过磁场施加器在处理体积内施加磁场。在至少一个贮库体积中，通过在施加的磁场中的功率吸收，通过沉积在体内的磁性，顺磁性和/或超顺磁性纳米颗粒可引入热能。提供场强值和可选的计算温度分布，以帮助用户规划热疗。

86. 发明申请

US20140031785A1 SYSTEM, DEVICE AND METHOD FOR ABLATION OF A VESSEL'S WALL FROM THE INSIDE 有权
标题翻译：用于从内部排出船舶壁的系统，装置和方法
公开(公告)号：US20140031785A1
公开(公告)日：2014-01-30
申请号：US14008922
申请日：2012-04-02
申请人： Bruno Schwagten , Glenn Van Langenhove
发明人： Bruno Schwagten , Glenn Van Langenhove
IPC分类号： A61B18/04
CPC分类号： A61B18/10 , A61B18/04 , A61B18/082 , A61B18/18 , A61B2018/00095 , A61B2018/00154 , A61B2018/00214 , A61B2018/00345 , A61B2018/00375 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00678 , A61B2018/00708 , A61B2018/00714 , A61B2018/0072 , A61B2018/00791 , A61B2018/00982 , A61B2090/3966 , A61F2/06 , A61F2/90 , A61F2210/0057 , A61F2220/0008 , A61F2250/0001 , A61M25/09 , A61N1/406 , A61N2/02
摘要： The current invention concerns systems, devices and methods for the ablation of a vessel's wall from the inside, more specifically to implant devices and to the ablation of the wall of one or more pulmonary veins (PV) from the inside, preferably transmural ablation and preferably at the level of the antrum. Hereby, one or more implant devices can be implanted in the vessels and can subsequently be heated by external energy-providing means.
摘要翻译：本发明涉及用于从内部消融容器壁的系统，装置和方法，更具体地涉及植入装置以及从内部消融一个或多个肺静脉（PV）的壁，优选地透壁消融在窦的水平。因此，可以将一个或多个植入装置植入容器中并且随后可以通过外部能量提供装置加热。

87. 发明申请

US20130261368A1 NON-INVASIVE AND MINIMALLY INVASIVE AND TIGHTLY TARGETED MINIMALLY INVASIVE THERAPY METHODS AND DEVICES FOR PARATHYROID TREATMENT 审中-公开
标题翻译：非入侵和最小的入侵和最小限度的最小的入侵治疗方法和用于PARATHYROID治疗的设备
公开(公告)号：US20130261368A1
公开(公告)日：2013-10-03
申请号：US13624841
申请日：2012-09-21
申请人： Alan N. Schwartz
发明人： Alan N. Schwartz
IPC分类号： A61N1/00 , A61N2/00 , A61N5/00
CPC分类号： A61B18/06 , A61B18/02 , A61B18/1477 , A61B2017/00743 , A61B2018/00017 , A61B2018/00196 , A61B2018/0022 , A61B2018/00279 , A61B2018/00428 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00708 , A61B2018/00791 , A61B2018/00839 , A61B2018/00863 , A61B2018/00875 , A61B2018/00994 , A61B2018/0262 , A61B2018/0293 , A61B2018/044 , A61B2018/1472 , A61B2090/378 , A61B2090/3908 , A61B2090/3966 , A61B2218/002 , A61M25/0068 , A61M2025/0046 , A61N1/00 , A61N1/406 , A61N2/004 , A61N5/00 , A61N5/1027 , A61N7/02 , A61N2007/025
摘要： Systems and method for treating organic tissue of a patient's body in precisely controlled regions of the body such as the parathyroid glands. The systems and methods include introducing an energy or substance into contact with target tissue to control functionality of the target tissue and preventing the energy or substance from contacting surrounding non-target tissues sufficiently that functionality of critical non-target tissues is substantially not affected.
摘要翻译：用于在身体的精确控制区域（例如甲状旁腺）中治疗患者身体的有机组织的系统和方法。系统和方法包括将能量或物质引入与靶组织接触以控制靶组织的功能，并防止能量或物质充分接触周围的非靶组织，使关键非靶组织的功能基本上不受影响。

88. 发明申请

US20120041291A1 Temporal control of a lumen traveling device in a body tube tree 有权
标题翻译：体管管中管腔行走装置的时间控制
公开(公告)号：US20120041291A1
公开(公告)日：2012-02-16
申请号：US13136679
申请日：2011-08-05
申请人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61B5/145 , A61B6/00 , A61B5/00 , A61B10/00 , A61M25/098 , A61M5/00 , B82Y5/00
CPC分类号： A61B1/041 , A61B1/00156 , A61B5/0022 , A61B5/0031 , A61B5/0071 , A61B5/01 , A61B5/02007 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B5/062 , A61B5/07 , A61B5/073 , A61B5/076 , A61B5/082 , A61B5/14539 , A61B5/14546 , A61B5/4064 , A61B5/411 , A61B5/418 , A61B5/4839 , A61B5/6852 , A61B7/00 , A61B10/0045 , A61B10/04 , A61B17/22 , A61B17/22012 , A61B18/20 , A61B34/73 , A61B2010/0077 , A61B2010/0225 , A61B2017/00022 , A61B2017/00345 , A61F2/82 , A61N1/406 , A61N7/00 , G06F19/00 , G16H40/67
摘要： Methods of controlling the operation of a device traveling in a body tube tree, including determining a time based on a signal from a timing device and performing an action based on the determined time, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described.
摘要翻译：控制在体管树中行进的装置的操作的方法，包括基于来自定时装置的信号确定时间并基于所确定的时间执行动作，该控制系统部分地或完全地位于流明行进设备。可以通过该设备执行各种动作，例如医疗或治疗目的。还描述了包括用于执行方法的指令的机器可读介质。

89. 发明申请

US20120035439A1 Map-based navigation of a body tube tree by a lumen traveling device 审中-公开
标题翻译：通过流明旅行装置的体管树的地图导航
公开(公告)号：US20120035439A1
公开(公告)日：2012-02-09
申请号：US13136678
申请日：2011-08-05
申请人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Bran Ferren , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61B5/07
CPC分类号： A61B1/041 , A61B1/00156 , A61B5/0022 , A61B5/0031 , A61B5/0071 , A61B5/01 , A61B5/02007 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B5/062 , A61B5/07 , A61B5/073 , A61B5/076 , A61B5/082 , A61B5/14539 , A61B5/14546 , A61B5/4064 , A61B5/411 , A61B5/418 , A61B5/4839 , A61B5/6852 , A61B7/00 , A61B10/0045 , A61B10/04 , A61B17/22 , A61B17/22012 , A61B18/20 , A61B34/73 , A61B2010/0077 , A61B2010/0225 , A61B2017/00022 , A61B2017/00345 , A61F2/82 , A61N1/406 , A61N7/00 , G16H40/67
摘要： Method of controlling the operation of a device traveling in a body tube tree, including, determining the location of the device on a map of the body tube tree and planning a path of travel for the device toward a target location. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described.
摘要翻译：控制在体管树中行进的装置的操作的方法，包括：在体管树的地图上确定装置的位置并规划装置朝向目标位置的行进路径。可以通过该设备执行各种动作，例如医疗或治疗目的。还描述了包括用于执行方法的指令的机器可读介质。

90. 发明申请

US20120035438A1 Path selection by a lumen traveling device in a body tub tree based on previous path 审中-公开
标题翻译：基于前一路径的体槽树中的流明行进装置的路径选择
公开(公告)号：US20120035438A1
公开(公告)日：2012-02-09
申请号：US13136676
申请日：2011-08-05
申请人： Bran Ferren , W. Daniel Hillis , Roderic A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
发明人： Bran Ferren , W. Daniel Hillis , Roderic A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Thomas J. Nugent, JR. , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y. H. Wood
IPC分类号： A61B5/07
CPC分类号： A61B1/041 , A61B1/00156 , A61B5/0022 , A61B5/0031 , A61B5/0071 , A61B5/01 , A61B5/02007 , A61B5/0215 , A61B5/026 , A61B5/03 , A61B5/062 , A61B5/07 , A61B5/073 , A61B5/076 , A61B5/082 , A61B5/14539 , A61B5/14546 , A61B5/4064 , A61B5/411 , A61B5/418 , A61B5/4839 , A61B5/6852 , A61B7/00 , A61B10/0045 , A61B10/04 , A61B17/22 , A61B17/22012 , A61B18/20 , A61B34/73 , A61B2010/0077 , A61B2010/0225 , A61B2017/00022 , A61B2017/00345 , A61F2/82 , A61N1/406 , A61N7/00 , G16H40/67
摘要： Methods of controlling the operation of a device traveling in a body tube tree, including selecting a direction of travel of the device through the body tube tree based upon whether or not the device has previous travelled in a particular direction, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described.
摘要翻译：控制在体管树中行进的装置的操作的方法，包括基于所述装置是否具有在特定方向上行进的装置选择所述装置通过所述主体管树的行进方向，所述方法由位于部分地或完全地在流明行进装置上。可以通过该设备执行各种动作，例如医疗或治疗目的。还描述了包括用于执行方法的指令的机器可读介质。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式