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81. 发明授权

US09092552B2 System monitor for monitoring functional modules of a system 有权
标题翻译：用于监控系统功能模块的系统监视器
公开(公告)号：US09092552B2
公开(公告)日：2015-07-28
申请号：US13872020
申请日：2013-04-26
申请人： CYBERONICS, INC.
发明人： Sujith V. Nair , Jamin L. Gingerich , Tushar R. Desai , Brian C. Tomayko
IPC分类号： G06F11/00 , G06F11/34 , G06F11/07 , G06F11/30 , A61B5/1495
CPC分类号： G06F11/34 , A61B5/0031 , A61B5/1495 , A61B2560/0271 , A61B2560/0276 , A61B2560/028 , A61N1/372 , A61N1/37211 , A61N1/37252 , G06F11/0757 , G06F11/0793 , G06F11/0796 , G06F11/3013 , G06F19/00 , G16H40/40
摘要： A method includes detecting a counter event at a system monitor of a system. The method also includes, in response to detecting the counter event, checking a state of each flag of a first set of flags. Each of the first set of flags is associated with a monitored module of the system, and the state of each of the first set of flags is indicated by a value at a memory location that is enabled. The method also includes, in response to determining that at least one flag of the first set of flags has a value indicating an error associated with a particular monitored module, causing an action to be performed at the system.
摘要翻译：一种方法包括在系统的系统监视器处检测计数器事件。该方法还包括响应于检测到计数器事件而检查第一组标志的每个标志的状态。第一组标志中的每一个与系统的监视模块相关联，并且第一组标志中的每一个的状态由启用的存储器位置处的值指示。该方法还包括响应于确定第一组标志的至少一个标志具有指示与特定监视模块相关联的错误的值，导致在系统处执行动作。

82. 发明申请

US20150202450A1 DIVERSITY ANTENNAS FOR NEUROSTIMULATOR PROGRAMMING DEVICES 有权
标题翻译：神经节细胞编程装置的多样性天线
公开(公告)号：US20150202450A1
公开(公告)日：2015-07-23
申请号：US14670539
申请日：2015-03-27
申请人： Greatbatch Ltd.
发明人： Stephen C. Trier , Raymond Lloyd Yoder
IPC分类号： A61N1/372
CPC分类号： A61N1/37223 , A61N1/36071 , A61N1/37211 , A61N1/37229 , A61N1/37235 , H01Q1/243 , H01Q1/273 , H01Q21/28 , H04B7/0686 , H04B7/0868 , H04B7/12
摘要： The present disclosure involves a method of communicating with an implantable medical device. A programmer is provided. The programmer has a plurality of diversity antennas. The diversity antennas are configured to send wireless signals to the implantable medical device. A subset of the diversity antennas is selected. A communications link is established between the programmer and the implantable medical device through the selected subset of the diversity antennas. A link quality of the communications link is measured. A different subset of the diversity antennas is selected to communicate with the implantable medical device if the link quality falls below a predetermined threshold.
摘要翻译：本公开涉及与可植入医疗装置通信的方法。提供程序员。编程器具有多个分集天线。分集天线被配置为向可植入医疗设备发送无线信号。选择分集天线的子集。通过所选择的分集天线的子集，在编程器和可植入医疗设备之间建立通信链路。测量通信链路的链路质量。如果链路质量低于预定阈值，则选择分集天线的不同子集以与可植入医疗装置进行通信。

83. 发明申请

US20150164481A1 ULTRASOUND DIAGNOSIS DEVICE AND OPERATING METHOD OF THE SAME 审中-公开
标题翻译：超声诊断装置及其操作方法
公开(公告)号：US20150164481A1
公开(公告)日：2015-06-18
申请号：US14572489
申请日：2014-12-16
申请人： SAMSUNG MEDISON CO., LTD.
发明人： Jin-yong LEE , Sung-wook PARK , Joo-hyun SONG , Bong-heon LEE , Hyuk-jae CHANG , Nam-sik CHUNG , Geu-ru HONG , Jong-hwa KIM , Sang-hoon SHIN
IPC分类号： A61B8/08 , G06T15/08 , A61B8/00
CPC分类号： A61B8/5253 , A61B8/0883 , A61B8/4405 , A61B8/4427 , A61B8/463 , A61B8/467 , A61B8/483 , A61B8/485 , A61B8/5207 , A61B8/5223 , A61B8/5246 , A61B8/565 , A61N1/37211 , G06T15/08
摘要： Disclosed are an ultrasound diagnosis device and an operating method of the same. The operating method of an ultrasound diagnosis device includes generating a first ultrasound image based on first ultrasound signals received from an object at a first point in time, calculating a value of at least one parameter of the object based on the first ultrasound image, generating a second ultrasound image based on second ultrasound signals received from the object at a second point in time, calculating a value of the at least one parameter of the object based on the second ultrasound image, and displaying a comparative image obtained by comparing the first and second ultrasound images and a comparative result obtained by comparing the calculated values of the at least one parameter.
摘要翻译：公开了一种超声诊断装置及其操作方法。超声诊断装置的操作方法包括基于从第一时间点从对象接收的第一超声信号生成第一超声图像，基于第一超声图像计算对象的至少一个参数的值，生成基于在第二时间点从对象接收的第二超声信号的第二超声图像，基于第二超声图像计算对象的至少一个参数的值，并且显示通过比较第一和第二超声图像获得的比较图像超声图像和通过比较所述至少一个参数的计算值而获得的比较结果。

84. 发明授权

US09042991B2 Implantable head mounted neurostimulation system for head pain 有权
标题翻译：用于头痛的植入式头部神经刺激系统
公开(公告)号：US09042991B2
公开(公告)日：2015-05-26
申请号：US14460139
申请日：2014-08-14
申请人： Syntilla Medical LLC
发明人： Kenneth Lyle Reed , Robert Raymond Bulger
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/3787 , A61N1/0504 , A61N1/0526 , A61N1/0529 , A61N1/0551 , A61N1/36075 , A61N1/37211 , A61N1/37229 , A61N1/37247 , A61N1/375
摘要： An implantable head-mounted unibody peripheral neurostimulation system is provided for implantation in the head for the purpose of treating chronic head pain, including migraine. The system may include an implantable pulse generator (IPG) from which multiple stimulating leads may extend sufficient to allow for adequate stimulation over multiple regions of the head, preferably including the frontal, parietal and occipital regions. A lead may include an extended body, along which may be disposed a plurality of surface metal electrodes, which may be sub-divided into a plurality of electrode arrays. A plurality of internal metal wires may run a portion of its length and connect the IPG's internal circuit to the surface metal electrodes. The IPG may include a rechargeable battery, an antenna, and an application specific integrated circuit. The IPG may be capable of functional connection with an external radiofrequency unit for purposes that may include recharging, diagnostic evaluation, and programming.
摘要翻译：为了治疗慢性头痛，包括偏头痛，提供了一种植入式头戴式一体外周神经刺激系统，用于植入头部。该系统可以包括可植入脉冲发生器（IPG），多个刺激引线可以从该可植入脉冲发生器延伸足以允许对头部的多个区域进行充分刺激，优选地包括额叶，顶叶和枕叶区域。引线可以包括延伸体，沿着该延伸体可以设置多个表面金属电极，其可以被细分成多个电极阵列。多个内部金属线可以延伸其长度的一部分并且将IPG的内部电路连接到表面金属电极。 IPG可以包括可充电电池，天线和专用集成电路。为了包括充电，诊断评估和编程的目的，IPG可能能够与外部射频单元进行功能连接。

85. 发明授权

US09031669B2 System for transvascularly stimulating autonomic targets 有权
标题翻译：经血管刺激自主神经系统
公开(公告)号：US09031669B2
公开(公告)日：2015-05-12
申请号：US13964807
申请日：2013-08-12
申请人： Cardiac Pacemakers, Inc.
发明人： Yunlong Zhang , Haresh G. Sachanandani , Dan Li , Bin Mi
IPC分类号： A61N1/05 , A61B5/00 , A61N1/36 , A61N1/372 , A61N1/362
CPC分类号： A61N1/0587 , A61B5/4035 , A61B5/6862 , A61B5/6876 , A61N1/057 , A61N1/36114 , A61N1/36117 , A61N1/3627 , A61N1/37211 , A61N1/37288
摘要： Various implantable medical device embodiments stimulate an autonomic neural target from within a pulmonary artery, and comprise at least one electrode, a power supply, a neural stimulator connected to the power supply, and an anchor structure. The neural stimulator is configured to generate a neural stimulation signal for delivery to the neural stimulation target through the at least one electrode. The anchor structure is configured to chronically and securely implant the neural stimulator, the power supply and the at least one electrode within the pulmonary artery. The anchor structure, the neural stimulator, the power supply and the at least one electrode are configured to be implanted through a pulmonary valve into the pulmonary artery. In various embodiments, the neural stimulator is configured to be operational to implement a neural stimulation protocol when chronically implanted within the pulmonary artery without a wired connection through the pulmonary valve.
摘要翻译：各种可植入医疗装置实施例从肺动脉内刺激自主神经靶标，并且包括至少一个电极，电源，连接到电源的神经刺激器和锚结构。神经刺激器被配置为产生神经刺激信号，以通过至少一个电极传递到神经刺激靶。锚结构被配置为长期且牢固地植入神经刺激器，电源和至少一个电极在肺动脉内。锚结构，神经刺激器，电源和至少一个电极构造成通过肺动脉瓣植入肺动脉。在各种实施例中，神经刺激器被配置为在长期植入肺动脉内而不通过肺动脉瓣的有线连接的情况下实施神经刺激方案。

86. 发明申请

US20150119958A1 SYSTEM AND METHOD TO AUTOMATICALLY INCORPORATE LEAD INFORMATION FROM MEDICAL IMAGE INTO PROGRAMMABLE USER INTERFACE 有权
标题翻译：系统和方法自动将铅信息从医学图像纳入可编程用户界面
公开(公告)号：US20150119958A1
公开(公告)日：2015-04-30
申请号：US14528461
申请日：2014-10-30
申请人： Boston Scientific Neuromodulation Corporation
发明人： Yue Li , Dennis Zottola
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61B6/12 , A61B5/4887 , A61B6/506 , A61N1/3606 , A61N1/36071 , A61N1/36128 , A61N1/36182 , A61N1/36185 , A61N1/37211 , A61N1/37247
摘要： An external control system for use with a neurostimulation device and at least one neurostimulation lead implanted within the tissue of a patient is provided. The external control system comprises a user interface configured for receiving input from a user, output circuitry configured for communicating with the neurostimulation device, and control/processing circuitry configured for receiving a medical image of the neurostimulation lead(s) relative to an anatomical structure, processing the medical image to detect the location of the neurostimulation lead(s) relative to the anatomical structure, generating a set of stimulation parameters based on the user input and the detected location of the neurostimulation lead(s) relative to the anatomical structure, and directing the output circuitry to transmit instructions to the neurostimulation device to convey electrical stimulation energy in accordance with the stimulation parameter set.
摘要翻译：提供了一种与神经刺激装置一起使用的外部控制系统和植入患者组织内的至少一种神经刺激引线。外部控制系统包括被配置为从用户接收输入的用户界面，被配置为与神经刺激装置进行通信的输出电路以及被配置为接收相对于解剖结构的神经刺激引线的医学图像的控制/处理电路，处理医学图像以检测神经刺激引线相对于解剖结构的位置，基于用户输入和神经刺激引线相对于解剖结构的检测位置产生一组刺激参数，以及引导输出电路将指令发送到神经刺激装置以根据刺激参数集传送电刺激能量。

87. 发明授权

US09020599B2 Combination therapy including peripheral nerve field stimulation 有权
标题翻译：组合疗法包括周围神经域刺激
公开(公告)号：US09020599B2
公开(公告)日：2015-04-28
申请号：US14109049
申请日：2013-12-17
申请人： Medtronic, Inc.
发明人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Kenneth T. Heruth , Paul W. Wacnik , Jeffrey S. Evanson
IPC分类号： A61N1/34 , A61M5/142 , A61N1/05 , A61N1/372 , A61N1/36 , A61N1/375
CPC分类号： A61N1/36021 , A61M5/14 , A61M5/142 , A61M2205/054 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/0558 , A61N1/36017 , A61N1/36071 , A61N1/37211 , A61N1/375
摘要： Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
摘要翻译：描述了外周神经区域刺激（PNFS）与一种或多种其他疗法的结合。与PNFS组合递送的另一疗法可以是例如不同类型的神经刺激，例如脊髓刺激（SCS）或药物。 PNFS和其他治疗可以根据时间表以交替方式同时递送，和/或选择性地，例如响应于从患者或临床医生接收到的请求。包括PNFS的联合治疗可能能够更全面地解决复杂或多焦点疼痛，而不仅仅是通过传送PNFS或其他疗法来实现。此外，PNFS与一种或多种其它疗法的组合可以降低神经调节可能损害所感知的有效性PNFS或其他疗法的可能性。

88. 发明授权

US08934963B1 Method and apparatus for monitoring arrythmogenic effects of medications using an implantable device 有权
标题翻译：用于使用可植入装置监测药物的致汗作用的方法和装置
公开(公告)号：US08934963B1
公开(公告)日：2015-01-13
申请号：US11623613
申请日：2007-01-16
申请人： Taraneh Ghaffari Farazi
发明人： Taraneh Ghaffari Farazi
IPC分类号： A61B5/0452 , A61B5/00
CPC分类号： A61B5/0452 , A61B5/04525 , A61B5/4839 , A61B5/4848 , A61N1/0563 , A61N1/3622 , A61N1/36507 , A61N1/36592 , A61N1/3684 , A61N1/37211
摘要： An implantable device and method for monitoring changes in the risk of arrhythmia induced by medications. The implantable device monitors risk of arrhythmia by analyzing an aspect of T-wave morphology to generate a metric of transmural dispersion of repolarization (“TDR”) as a proxy for the risk of arrhythmia. The implantable device generates an index of change in the risk of arrhythmia by comparing values of the metric of TDR obtained for different time periods. The implantable device generates a warning if the change in risk of arrhythmia is outside acceptable limits. The implantable device can also communicate with other devices to correlate changes in risk of arrhythmia with medications taken by the patient.
摘要翻译：用于监测由药物引起的心律失常风险变化的可植入装置和方法。可植入装置通过分析T波形态的一个方面来监测心律不齐的风险，以产生一种度量的复极化的透壁性分散（“TDR”）作为心律失常风险的代表。通过比较不同时间段获得的TDR的度量值，可植入装置产生心律失常风险的变化指标。如果心律失常风险的变化超出了可接受的限度，植入式装置会产生警告。可植入装置还可以与其他装置通信，以将心律不齐的风险变化与患者所采取的药物相关联。

89. 发明申请

US20140316478A1 SYSTEMS FOR REGULATION OF BLOOD PRESSURE AND HEART RATE 有权
标题翻译：用于调节血压和心率的系统
公开(公告)号：US20140316478A1
公开(公告)日：2014-10-23
申请号：US14319529
申请日：2014-06-30
申请人： EnteroMedics Inc.
发明人： Katherine S. Tweden , Richard R. Wilson , Mark B. Knudson , Dennis Dong-Won Kim , Deepak Bhole
IPC分类号： A61N1/36 , A61N1/378 , A61N1/372
CPC分类号： A61N1/36117 , A61N1/36053 , A61N1/36114 , A61N1/36139 , A61N1/37211 , A61N1/3787
摘要： A method and apparatus for treating a condition associated with impaired blood pressure and/or heart rate in a subject comprising applying an electrical treatment signal, wherein the electrical treatment signal is selected to at least partially block nerve impulses, or in some embodiments, to augment nerve impulses.
摘要翻译：一种用于治疗与受试者中受损的血压和/或心率相关的病症的方法和装置，包括施加电治疗信号，其中所述电治疗信号被选择为至少部分阻断神经冲动，或在一些实施例中增加神经冲动

90. 发明授权

US08868198B2 Heuristic safety net for transitioning configurations in a neural stimulation system 有权
标题翻译：用于神经刺激系统中过渡配置的启发式安全网
公开(公告)号：US08868198B2
公开(公告)日：2014-10-21
申请号：US13849375
申请日：2013-03-22
申请人： Boston Scientific Neuromodulation Corporation
发明人： Dongchul Lee , Changfang Zhu
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36185 , A61N1/0551 , A61N1/36142 , A61N1/37211 , A61N1/37247 , A61N1/37264
摘要： A system and method using a plurality of electrodes. An immediate virtual multipole is defined, an immediate electrode configuration emulating the immediate virtual multipole is defined, electrical energy is conveyed to the electrodes in accordance with the immediate electrode configuration, a new virtual multipole is defined by changing a parameter of the immediate virtual multipole by a step size, a new electrode configuration that emulates the new virtual multipole is defined, a difference value as a function of the immediate virtual multipole and the new virtual multipole is computed, the different value is compared to a limit value, electrical energy is conveyed to the electrodes in accordance with the new electrode configuration if the difference value does not exceed the limit value, and the absolute value of the step size is decreased to create a new step size if the difference value does exceed the limit value.
摘要翻译：一种使用多个电极的系统和方法。定义立即虚拟多极，定义仿真立即虚拟多极的立即电极配置，根据直接电极配置将电能传送到电极，新的虚拟多极通过将立即虚拟多极的参数改变定义步长，模拟新的虚拟多极的新电极配置，计算作为立即虚拟多极和新虚拟多极的函数的差值，将不同值与极限值进行比较，传送电能如果差值不超过极限值，则根据新电极配置到电极，并且如果差值超过极限值，则步长的绝对值减小以产生新的步长。

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