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    • 81. 发明申请
    • Tissue Extraction and Collection Device
    • 组织提取和收集装置
    • US20080234715A1
    • 2008-09-25
    • US12056637
    • 2008-03-27
    • Robert S. PesceShelby CookKristian DiMatteoKevin RanucciRobert Boock
    • Robert S. PesceShelby CookKristian DiMatteoKevin RanucciRobert Boock
    • A61B17/32
    • A61B10/025A61B10/0096A61B10/0266A61B10/0283A61B17/1635A61B17/32002A61B2017/320064A61B2090/0807
    • Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges.
    • 公开了用于提取和收集组织的方法和装置,其可以用于组织工程和移植应用中。 在一个实施例中,装置可以包括外管。 旋转轴可以设置在外管内,可以具有形成在其远端上的组织收集尖端,组织收集尖端有效地在旋转时切除组织。可以包括组织收集装置以接收和收集切除的组织,并且 组织收集装置可以指示其中收集的组织的量。 例如,组织收集装置可以包括收集切除的组织的应变元件和用于评估收集的组织的量的指示器。 在一些实施例中,组织收集装置可以平移以指示收集的组织的量。 在许多情况下,本文公开的装置可以包括适于驱动组织收集尖端的驱动机构,使得尖端切除软组织,但是当接触骨骼时(或者在接触骨骼之后不久)停止。 在一些实施方案中,组织采集尖端可有效地切除活组织样品,使得样品可以显示出所需比例的活细胞。 此外,在一些实施例中,组织采集尖端可以用落在一定尺寸范围内的组织颗粒来切除组织样本。